The role of Eph/ephrin molecules in stromal–hematopoietic interactions

scientific article published on 16 October 2015

The role of Eph/ephrin molecules in stromal–hematopoietic interactions is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1029321863
P356DOI10.1007/S12185-015-1886-X
P698PubMed publication ID26475284
P5875ResearchGate publication ID282945169

P50authorStan GronthosQ61478070
P2093author name stringThao M Nguyen
Agnieszka Arthur
P2860cites workMutations of the ephrin-B1 gene cause craniofrontonasal syndromeQ24533993
Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurredQ24534800
Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndromeQ24564244
Eph/ephrin molecules--a hub for signaling and endocytosisQ24611588
Non-SH2/PDZ reverse signaling by ephrinsQ24629619
A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytesQ28141013
Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular developmentQ28145776
'Eph'ective signaling: forward, reverse and crosstalkQ28179338
Ephrin stimulation modulates T cell chemotaxisQ28202034
Mechanisms and functions of Eph and ephrin signallingQ28208291
The Eph family of receptorsQ28251298
A novel putative tyrosine kinase receptor encoded by the eph geneQ28280591
Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesisQ28510537
EphrinB1 is essential in T-cell-T-cell co-operation during T-cell activationQ28584835
Eph-ephrin bidirectional signaling in physiology and diseaseQ29617975
Eph receptor signalling casts a wide net on cell behaviourQ29619988
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironmentQ29620053
Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.Q33555818
Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells.Q33558170
The impact of CFNS-causing EFNB1 mutations on ephrin-B1 functionQ33610885
Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1.Q33613966
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.Q33895889
Eph receptors and ephrins in cancer: bidirectional signalling and beyondQ34021365
Multiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsQ34038854
Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries.Q34127484
A stem cell molecular signatureQ34149366
Nice neighborhood: emerging concepts of the stem cell nicheQ34165273
The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cellsQ34704081
EphB6 crosslinking results in costimulation of T cellsQ34785859
EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblastsQ34796085
Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cellsQ67898011
Osteogenesis in transplants of bone marrow cellsQ71202383
Mobilization of CD34+ haematopoietic stem cells is associated with a functional inactivation of the integrin very late antigen 4Q74129075
Thymic alterations in EphA4-deficient miceQ79834573
Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptorsQ81411101
Prospective isolation of mesenchymal stem cells from mouse compact boneQ83001056
A high affinity recombinant antibody to the human EphA3 receptor with enhanced ADCC activityQ35441094
Bone cell interactions through Eph/ephrin: bone modeling, remodeling and associated diseasesQ36402724
Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow nichesQ36691868
Cell-cell signaling via Eph receptors and ephrinsQ36967529
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitorsQ37078786
The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growthQ37334601
Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients.Q37481237
EPHA3 as a novel therapeutic target in the hematological malignanciesQ38025161
Eph/Ephrin signaling in injury and inflammationQ38047589
Therapeutic targeting of EPH receptors and their ligandsQ38174793
EphA3 biology and cancer.Q38267753
Stromal cells modulate ephrinB2 expression and transmigration of hematopoietic cellsQ38314937
Targeting EphA3 inhibits cancer growth by disrupting the tumor stromal microenvironmentQ38965799
EphB/ephrin-B interactions mediate human MSC attachment, migration and osteochondral differentiation.Q39634908
Activation of ephrin A proteins influences hematopoietic stem cell adhesion and trafficking patternsQ39676355
Ephrin-B1 reverse signaling controls a posttranscriptional feedback mechanism via miR-124.Q40338388
A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesisQ40727092
Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cellsQ40740770
EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.Q40879915
Single adult human CD34(+)/Lin-/CD38(-) progenitors give rise to natural killer cells, B-lineage cells, dendritic cells, and myeloid cellsQ40986235
Hematopoietic stem cells: Inferences from in vivo assaysQ41642017
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assemblyQ42168707
EphB and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells.Q42962199
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenanceQ43226905
Ephrin B2 induces T cell costimulationQ44484553
Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediatorsQ44796947
Ephrin-A1 binding to CD4+ T lymphocytes stimulates migration and induces tyrosine phosphorylation of PYK2.Q45178519
Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.Q45859658
Circulating N-cadherin levels are a negative prognostic indicator in patients with multiple myeloma.Q46263392
Eph/ephrinB mediate dental pulp stem cell mobilization and functionQ46274342
Greater bone formation of Y2 knockout mice is associated with increased osteoprogenitor numbers and altered Y1 receptor expressionQ46279970
Eph-ephrin promiscuity is now crystal clearQ47683124
Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood.Q51239401
Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulpQ52107163
Smad3 contributes to positioning of proliferating cells in colonic crypts by inducing EphB receptor protein expressionQ53271592
Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissuesQ53745526
Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivoQ54011232
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritisQ54494658
Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenanceQ54540120
EphB/ephrin-B interaction mediates adult stem cell attachment, spreading, and migration: implications for dental tissue repair.Q54564139
EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repairQ57265491
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasisQ57675131
Human mulipotential mesenchymal/stromal stem cells are derived from a discrete subpopulation of STRO-1bright/CD34 /CD45 /glycophorin-A-bone marrow cellsQ59696069
P433issue2
P304page(s)145-154
P577publication date2016-02-01
P1433published inInternational Journal of HematologyQ6051416
P1476titleThe role of Eph/ephrin molecules in stromal–hematopoietic interactions
P478volume103

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cites work (P2860)
Q38840851Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair
Q39356254Ephrin ligands and Eph receptors contribution to hematopoiesis
Q86964654Guest editorial: Human mesenchymal stromal/stem cell (MSC)
Q39534918Stimulatory Effects of Mesenchymal Stem Cells on cKit+ Cardiac Stem Cells Are Mediated by SDF1/CXCR4 and SCF/cKit Signaling Pathways
Q38743958Truncated EphA2 likely potentiates cell adhesion via integrins as well as infiltration and/or lodgment of a monocyte/macrophage cell line in the red pulp and marginal zone of the mouse spleen, where ephrin-A1 is prominently expressed in the vasculat

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