| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2016NatCo...711792N |
| P356 | DOI | 10.1038/NCOMMS11792 |
| P932 | PMC publication ID | 4899630 |
| P698 | PubMed publication ID | 27273569 |
| P50 | author | Ted M. Dawson | Q56046960 |
| Christopher A Ross | Q84166596 | ||
| Darren J Moore | Q87693446 | ||
| P2093 | author name string | Dong Wei | |
| Akira Sawa | |||
| Juan C Troncoso | |||
| Xiao-Fang Wang | |||
| Nicolas Arbez | |||
| Frederick C Nucifora | |||
| Leslie G Nucifora | |||
| Olga Pletnikova | |||
| Chee-Hoe Ng | |||
| Simone Engelender | |||
| Vered Shani | |||
| Kah-Leong Lim | |||
| Tianxia Li | |||
| Yajuan Guo | |||
| Wanli Smith | |||
| Elaine Roby | |||
| P2860 | cites work | A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations | Q57623830 |
| Analysis of 14 LRRK2 mutations in Parkinson's plus syndromes and late-onset Parkinson's disease | Q83121503 | ||
| Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 | ||
| Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity | Q24290192 | ||
| Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1 | Q24290518 | ||
| The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 | ||
| A huntingtin-associated protein enriched in brain with implications for pathology | Q24303499 | ||
| Kinase activity of mutant LRRK2 mediates neuronal toxicity | Q24303603 | ||
| Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1 | Q24304257 | ||
| Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation | Q24312713 | ||
| Origin and function of ubiquitin-like proteins | Q24651141 | ||
| The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate | Q24669733 | ||
| Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface | Q27670574 | ||
| A Strategy for Modulation of Enzymes in the Ubiquitin System | Q27675727 | ||
| The ubiquitin system | Q27860803 | ||
| Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology | Q28131833 | ||
| The leucine-rich repeat as a protein recognition motif | Q28212461 | ||
| The importance of LRRK2 mutations in Parkinson disease | Q28263075 | ||
| Clinical and pathologic features of families with LRRK2-associated Parkinson's disease | Q28266674 | ||
| Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun | Q28283776 | ||
| Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death | Q28287762 | ||
| Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease | Q28292932 | ||
| Parkinson's disease: mechanisms and models | Q29547424 | ||
| An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family. | Q30350674 | ||
| Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease | Q33841155 | ||
| NF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activation | Q33915312 | ||
| Ubiquitin in chains | Q33925675 | ||
| Recent advances in the genetics of Parkinson's disease | Q34189660 | ||
| Roc, a Ras/GTPase domain in complex proteins | Q34280792 | ||
| Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease | Q34331409 | ||
| Identification of Novel Potentially Toxic Oligomers Formed in Vitro from Mammalian-derived Expanded huntingtin Exon-1 Protein | Q35939753 | ||
| Molecular pathophysiology of Parkinson's disease | Q36196507 | ||
| The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease | Q36325701 | ||
| Parkinsonism genes: culprits and clues | Q36534256 | ||
| α-Synuclein oligomers and clinical implications for Parkinson disease | Q36718306 | ||
| CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity | Q37115256 | ||
| Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila. | Q37408628 | ||
| A critical evaluation of the ubiquitin-proteasome system in Parkinson's disease | Q37472304 | ||
| LRRK2 and Parkinson disease | Q37748314 | ||
| Ubiquitin pathways in neurodegenerative disease | Q38234883 | ||
| Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown | Q38583853 | ||
| Leucine-rich repeat kinase 2 is associated with the endoplasmic reticulum in dopaminergic neurons and accumulates in the core of Lewy bodies in Parkinson disease | Q39665853 | ||
| Biochemical and pathological characterization of Lrrk2. | Q40324969 | ||
| Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease | Q42675021 | ||
| Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation. | Q42813788 | ||
| Proteasome inhibition causes nigral degeneration with inclusion bodies in rats | Q44094584 | ||
| TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains. | Q48125960 | ||
| Frequency of LRRK2 mutations in early- and late-onset Parkinson disease | Q48392751 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 11792 | |
| P577 | publication date | 2016-06-07 | |
| P1433 | published in | Nature Communications | Q573880 |
| P1476 | title | Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. | |
| P478 | volume | 7 |
| Q41653839 | A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation |
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| Q92240507 | Emerging drug development technologies targeting ubiquitination for cancer therapeutics |
| Q90375075 | GTP-binding inhibitors increase LRRK2-linked ubiquitination and Lewy body-like inclusions |
| Q92058815 | LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function |
| Q96953324 | LRRK2 Phosphorylation, More Than an Epiphenomenon |
| Q64969037 | Mechanisms of protein toxicity in neurodegenerative diseases. |
| Q91707618 | Nonproteolytic K29-Linked Ubiquitination of the PB2 Replication Protein of Influenza A Viruses by Proviral Cullin 4-Based E3 Ligases |
| Q89700542 | Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP |
| Q54979954 | TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis. |
| Q91013930 | Targeted protein degradation: expanding the toolbox |
| Q64811522 | The role of posttranslational modifications of α-synuclein and LRRK2 in Parkinson's disease: Potential contributions of environmental factors |
| Q98946924 | Ubiquitination status does not affect Vps34 degradation |
| Q26740274 | WSB1: from homeostasis to hypoxia |
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