Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer.

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Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-08-0553
P932PMC publication ID2599903
P698PubMed publication ID19010927

P50authorSara GandiniQ51845664
Aliana Guerrieri GonzagaQ73008383
P MagniQ73056695
Massimiliano RuscicaQ39688513
P2093author name stringBernardo Bonanni
Franca Formelli
Andrea Decensi
Simona Iodice
Harriet Johansson
Marcella Gulisano
P2860cites workElevated retinol-binding protein 4 levels are associated with metabolic syndrome in Chinese people.Q51463161
Insulin resistance and breast-cancer riskQ54259823
Energy balance, insulin resistance biomarkers, and breast cancer risk.Q55474697
Increased prevalence of prior breast cancer in women with newly diagnosed diabetesQ60595426
Long-term tolerability of fenretinide (4-HPR) in breast cancer patientsQ67904678
The effect of the anti-estrogen tamoxifen on cardiovascular risk factors in normal postmenopausal womenQ71825679
Pilot trial of the safety, tolerability, and retinoid levels of N-(4-hydroxyphenyl) retinamide in combination with tamoxifen in patients at high risk for developing invasive breast cancerQ73358697
Delayed severe hypertriglyceridemia from tamoxifenQ73524655
Retinol binding protein as a surrogate measure for serum retinol: studies in vitamin A-deficient children from the Republic of the Marshall IslandsQ73585715
Severe hypertriglyceridemia caused by tamoxifen-treatment after breast cancer surgeryQ74184152
Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal womenQ79182457
Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjectsQ79759732
Tolerability of the synthetic retinoid Fenretinide (HPR)Q93512087
Plasma retinol level reduction by the synthetic retinoid fenretinide: a one year follow-up study of breast cancer patientsQ93521069
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetesQ24309211
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in manQ26776977
Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancerQ28238331
Five-year administration of fenretinide: pharmacokinetics and effects on plasma retinol concentrationsQ28264846
Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 StudyQ28283241
Tamoxifen for the prevention of breast cancer: late results of the Italian Randomized Tamoxifen Prevention Trial among women with hysterectomyQ28300092
Western nutrition and the insulin resistance syndrome: a link to breast cancerQ33547366
Weighing the risks and benefits of tamoxifen treatment for preventing breast cancerQ33765709
Incidence and risk factors for non-alcoholic steatohepatitis: prospective study of 5408 women enrolled in Italian tamoxifen chemoprevention trialQ33937093
Tamoxifen-induced severe hypertriglyceridemia and pancreatitis.Q34064360
Effect of tamoxifen on venous thromboembolic events in a breast cancer prevention trial.Q34392166
Molecular links between obesity and breast cancerQ34530905
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjectsQ34538317
Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progressionQ36885845
Adiposity, type 2 diabetes and the metabolic syndrome in breast cancerQ36918192
Leptin receptor-deficient MMTV-TGF-alpha/Lepr(db)Lepr(db) female mice do not develop oncogene-induced mammary tumorsQ38345749
Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumorsQ38357353
Leptin--a growth factor in normal and malignant breast cells and for normal mammary gland developmentQ38360743
Distribution of fenretinide in the mammary gland of breast cancer patientsQ38534184
Tamoxifen therapy for breast cancer and endometrial cancer risk.Q41694508
Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cellsQ42440477
Stimulation of endometrial cancer cell growth by tamoxifen is associated with increased insulin-like growth factor (IGF)-I induced tyrosine phosphorylation and reduction in IGF binding proteinsQ42516031
High insulin levels in newly diagnosed breast cancer patients reflect underlying insulin resistance and are associated with components of the insulin resistance syndromeQ43815284
Inhibition of glucose-induced electrical activity by 4-hydroxytamoxifen in rat pancreatic beta-cellsQ43826569
A randomized trial of low-dose tamoxifen on breast cancer proliferation and blood estrogenic biomarkersQ44463946
Effects of tamoxifen treatment on plasma lipids and lipoprotein lipid compositionQ44541096
Differential effects of leptin on cancer in vitroQ44895551
Endogenous sex hormones and subsequent breast cancer in premenopausal womenQ45047695
Insulin resistance and clinical aspects of non-alcoholic steatohepatitis (NASH).Q46428394
Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).Q46495873
Functional role of RXRs and PPARgamma in mature adipocytes.Q46528965
Influence of age on the association of retinol-binding protein 4 with metabolic syndromeQ46779329
Preliminary results on safety and activity of a randomized, double-blind, 2 x 2 trial of low-dose tamoxifen and fenretinide for breast cancer prevention in premenopausal women.Q46871181
Metabolic syndrome as a prognostic factor for breast cancer recurrencesQ46922126
Prevalence of insulin resistance in metabolic disorders: the Bruneck Study.Q50864806
P433issue22
P407language of work or nameEnglishQ1860
P921main subjecttamoxifenQ412178
preproinsulinQ7240673
P304page(s)9512-9518
P577publication date2008-11-01
P1433published inCancer ResearchQ326097
P1476titleEffect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer
P478volume68

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cites work (P2860)
Q92091998A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors
Q35558983Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study
Q28534795Association of serum retinol binding protein 4 with atherogenic dyslipidemia in morbid obese patients
Q93152835Cardiometabolic Effects of Endocrine Treatment of Estrogen Receptor-Positive Early Breast Cancer
Q34334262Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial.
Q47246053Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD).
Q33923490Estradiol Binds to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro
Q36006997Fenretinide prevents lipid-induced insulin resistance by blocking ceramide biosynthesis
Q51005071Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen signaling.
Q36635330Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus.
Q36547331GPER1-mediated IGFBP-1 induction modulates IGF-1-dependent signaling in tamoxifen-treated breast cancer cells
Q57287654Immune cells in the tumor: new roads of retinoids for chemoprevention and chemotherapeutics
Q37180380Impact of obesity on cancer survivorship and the potential relevance of race and ethnicity
Q34557490Intervening on the side effects of hormone-dependent cancer treatment: the role of strength training.
Q39671678Isolated and combined action of tamoxifen and metformin in wild-type, tamoxifen-resistant, and estrogen-deprived MCF-7 cells
Q37474455Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis
Q39986644Metformin, insulin, breast cancer and more...
Q26861403Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells
Q37845832Oxidative stress and therapeutic opportunities: focus on the Ewing's sarcoma family of tumors
Q64074583Potential therapeutic targets for atherosclerosis in sphingolipid metabolism
Q35665099Prognostic effect of circulating adiponectin in a randomized 2 x 2 trial of low-dose tamoxifen and fenretinide in premenopausal women at risk for breast cancer.
Q35762679Quantitative measurement of full-length and C-terminal proteolyzed RBP4 in serum of normal and insulin-resistant humans using a novel mass spectrometry immunoassay
Q90293197RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women
Q36570962Retinol as a cofactor for PKCδ-mediated impairment of insulin sensitivity in a mouse model of diet-induced obesity
Q26767191Retinol as electron carrier in redox signaling, a new frontier in vitamin A research
Q35478457Signaling by vitamin A and retinol-binding protein in regulation of insulin responses and lipid homeostasis
Q39129668The effect of selective estrogen receptor modulators on type 2 diabetes onset in women: Basic and clinical insights.
Q35532291Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice
Q36117484Two protein kinase C isoforms, δ and ε, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex
Q39199843Vitamin A as PKC Co-factor and Regulator of Mitochondrial Energetics

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