Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen signaling.

scientific article published on 14 July 2015

Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen signaling. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/OBY.21164
P698PubMed publication ID26179846

P50authorNimesh ModyQ57321366
Mirela DelibegovicQ84021168
P2093author name stringClaire Henderson
George D Mcilroy
Peter J McCaffery
Kirsty D Shearer
Nicola Morrice
Jenny Reekie
P2860cites workEstrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistanceQ36560629
Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus.Q36635330
Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer.Q37008398
Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob miceQ37264601
Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosisQ37474455
Minireview: Putting physiology back into estrogens' mechanism of actionQ37939510
Maternal adiposity--a determinant of perinatal and offspring outcomes?Q38046084
Impact of parity on obesity: a cross-sectional study in Iranian womenQ40235385
Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: results from the Women's Health Initiative Hormone Trial.Q40496635
Retinoic acid receptor beta expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamideQ41049278
Adipose tissue overexpression of vascular endothelial growth factor protects against diet-induced obesity and insulin resistance.Q42103747
Glycemic effects of postmenopausal hormone therapy: the Heart and Estrogen/progestin Replacement Study. A randomized, double-blind, placebo-controlled trialQ44269768
4-Hydroxyphenyl retinamide is a highly selective activator of retinoid receptorsQ46690362
Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancerQ24295934
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetesQ24309211
Modification of the oestrous cycle of the mouse by external stimuli associated with the maleQ28213059
Maternal obesity and risk of gestational diabetes mellitusQ28297113
Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female miceQ28590055
Serum immunoreactive-leptin concentrations in normal-weight and obese humansQ29617230
Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgammaQ33347137
Childbearing is associated with higher incidence of the metabolic syndrome among women of reproductive age controlling for measurements before pregnancy: the CARDIA studyQ33595899
Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERalpha-deficient miceQ33655519
Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice.Q33926507
Estrogen receptor-{beta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in miceQ34181302
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjectsQ34538317
The emergence of the metabolic syndrome with menopauseQ35146342
Multiparity leads to obesity and inflammation in mothers and obesity in male offspringQ35780719
Increased adipose tissue in male and female estrogen receptor-alpha knockout miceQ35823619
Aromatase-deficient (ArKO) mice have a phenotype of increased adiposityQ35823766
Recent female mouse models displaying advanced reproductive agingQ36341058
Clinical trials with retinoids for breast cancer chemopreventionQ36443030
P433issue8
P921main subjectobesityQ12174
P304page(s)1655-1662
P577publication date2015-07-14
P1433published inObesityQ15763232
P1476titleFenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen signaling
P478volume23

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cites work (P2860)
Q39399025Alterations in vitamin A/retinoic acid homeostasis in diet-induced obesity and insulin resistance.
Q47246053Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD).
Q37678960Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice.
Q39076546Gene expression modulation of lipid and central energetic metabolism related genes by high-fat diet intake in the main homeostatic tissues
Q47555468Modest Decreases in Endogenous All-Trans-Retinoic Acid Produced by a Mouse Rdh10 Heterozygote Provoke Major Abnormalities in Adipogenesis and Lipid Metabolism.