Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice

scientific article published on 19 February 2008

Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00521.2007
P932PMC publication ID2711779
P698PubMed publication ID18285525
P5875ResearchGate publication ID5565589

P50authorBarbara KahnQ60572402
P2093author name stringNimesh Mody
Qin Yang
Timothy E Graham
Yuki Tsuji
P2860cites workSerum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetesQ24309211
Structure of a complex of two plasma proteins: transthyretin and retinol-binding proteinQ27730236
Inflammation and metabolic disordersQ27860923
The Ile-84-->Ser amino acid substitution in transthyretin interferes with the interaction with plasma retinol-binding proteinQ28248404
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Disruption of the transthyretin gene results in mice with depressed levels of plasma retinol and thyroid hormoneQ28609142
Weight-reducing effects of the plasma protein encoded by the obese geneQ29617934
Adipocytes as regulators of energy balance and glucose homeostasisQ29619448
A novel compound heterozygote (FAP ATTR Arg104His/ATTR Val30Met) with high serum transthyretin (TTR) and retinol binding protein (RBP) levels.Q30797179
Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosisQ30968181
Biochemical basis for depressed serum retinol levels in transthyretin-deficient miceQ31470358
Distinct positive and negative elements control the limited hepatocyte and choroid plexus expression of transthyretin in transgenic miceQ33918459
Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion couplingQ34144525
Transthyretin mutations in hyperthyroxinemia and amyloid diseasesQ34269382
The role of the leptin in reproductionQ34532160
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjectsQ34538317
Obesity, insulin resistance, and cardiovascular diseaseQ35641849
Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjectsQ79759732
Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetesQ79771152
Circulating retinol-binding protein-4, insulin sensitivity, insulin secretion, and insulin disposition index in obese and nonobese subjectsQ80117549
Retinol binding protein-4 levels and clinical features of type 2 diabetes patientsQ80171630
Raised serum, adipocyte, and adipose tissue retinol-binding protein 4 in overweight women with polycystic ovary syndrome: effects of gonadal and adrenal steroidsQ80210509
Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat massQ80586267
Leptin and renal diseaseQ82306235
Plasma retinol level reduction by the synthetic retinoid fenretinide: a one year follow-up study of breast cancer patientsQ93521069
Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer regionQ35774807
Leptin, obesity and cardiovascular diseaseQ35808519
Retinol binding protein 4 as a candidate gene for type 2 diabetes and prediabetic intermediate traitsQ35944715
Novel roles for acylation stimulating protein/C3adesArg: a review of recent in vitro and in vivo evidenceQ36053046
Convergence between bone and energy homeostases: leptin regulation of bone massQ36644728
Role of leptin in immunityQ36755953
Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genesQ36763447
Transcriptional control of the mouse prealbumin (transthyretin) gene: both promoter sequences and a distinct enhancer are cell specificQ36902562
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular diseaseQ37742798
Identification of a regulatory SNP in the retinol binding protein 4 gene associated with type 2 diabetes in MongoliaQ40226584
Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammationQ40236661
Insulin resistance in liver cirrhosis is not associated with circulating retinol-binding protein 4.Q40237198
Role of VLDL/chylomicron in amyloid formation in familial amyloidotic polyneuropathyQ44638577
Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?Q45042253
Post-translational modification of transthyretin in plasmaQ47680557
Chylomicron-specific enhancement of acylation stimulating protein and precursor protein C3 production in differentiated human adipocytesQ47724554
Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients.Q50775960
Elevated serum RBP4 is associated with insulin resistance in women with polycystic ovary syndrome.Q51470772
Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents.Q51478598
Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes.Q51486811
Analysis of the factors contributing to serum retinol binding protein and transthyretin levels in Japanese adults.Q51492326
Retinol, alpha-tocopherol and carotenoids in diabetes.Q51561255
Association of serum retinol-binding protein 4 and visceral adiposity in Chinese subjects with and without type 2 diabetes.Q51751063
Thyroid hormone metabolism in a transthyretin-null mouse strain.Q52510809
Retinoids and retinoid-binding protein expression in rat adipocytesQ53850083
Investigation into thiol conjugation of transthyretin in hereditary transthyretin amyloidosisQ57259480
Plasma Levels and Adipose Tissue Messenger Ribonucleic Acid Expression of Retinol-Binding Protein 4 Are Reduced during Calorie Restriction in Obese Subjects but Are Not Related to Diet-Induced Changes in Insulin SensitivityQ57420151
Ethnicity, Insulin Resistance, and Inflammatory Adipokines in Women at High and Low Risk for Vascular DiseaseQ57711788
Tabulation of human transthyretin (TTR) variants, 2003Q58011075
Changes in urinary retinol binding protein excretion and other indices of renal tubular damage in patients with non-insulin dependent diabetesQ67472592
In vitro interaction of fenretinide with plasma retinol-binding protein and its functional consequencesQ67546270
Blood volume of obese (ob-ob) and diabetic (db-db) miceQ71412826
Comparison of urinary excretion of albumin, alpha 1-microglobulin and retinol-binding protein in diabetic patientsQ71736364
Retinopathy in type II diabetes mellitus associated with above-normal urinary excretion of RBPQ72576914
Evidence of oxidant injury and tubular damage in early diabetic nephropathyQ72874748
Urinary protein excretion in Type 2 diabetes with complicationsQ73290100
P433issue4
P921main subjectinsulin resistanceQ1053470
preproinsulinQ7240673
P304page(s)E785-93
P577publication date2008-02-19
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleDecreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice
P478volume294

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