| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Tony Hunter | |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| protein ubiquitination | Q3547638 | ||
| P304 | page(s) | 730-738 | |
| P577 | publication date | 2007-12-01 | |
| P1433 | published in | Molecular Cell | Q3319468 |
| P1476 | title | The age of crosstalk: phosphorylation, ubiquitination, and beyond | |
| P478 | volume | 28 |
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| Q35214900 | A Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin |
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| Q38805774 | A Generic Platform for Cellular Screening Against Ubiquitin Ligases |
| Q33787483 | A bird's-eye view of post-translational modifications in the spliceosome and their roles in spliceosome dynamics |
| Q35148553 | A chemical proteomics approach for global analysis of lysine monomethylome profiling. |
| Q33605445 | A coming-of-age story: activation-induced cytidine deaminase turns 10. |
| Q37431862 | A conserved phosphorylation site within the forkhead domain of FoxM1B is required for its activation by cyclin-CDK1. |
| Q41643207 | A critical appraisal of quantitative studies of protein degradation in the framework of cellular proteostasis |
| Q33999494 | A cytoplasmic negative regulator isoform of ATF7 impairs ATF7 and ATF2 phosphorylation and transcriptional activity |
| Q27939281 | A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis |
| Q48514111 | A mutational analysis of the cytosolic domain of the tomato Cf-9 disease-resistance protein shows that membrane-proximal residues are important for Avr9-dependent necrosis. |
| Q40568045 | A novel method for predicting post-translational modifications on serine and threonine sites by using site-modification network profiles |
| Q51556120 | A novel network-based computational method to predict protein phosphorylation on tyrosine sites. |
| Q90134320 | A phyB-PIF1-SPA1 kinase regulatory complex promotes photomorphogenesis in Arabidopsis |
| Q50881680 | A simple toolset to identify endogenous post-translational modifications for a target protein: a snapshot of the EGFR signaling pathway. |
| Q47098359 | A validated antibody panel for the characterization of tau post-translational modifications |
| Q52430975 | AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension. |
| Q27312743 | ATM functions at the peroxisome to induce pexophagy in response to ROS. |
| Q35351912 | ATP6AP2/(pro)renin receptor contributes to glucose metabolism via stabilizing the pyruvate dehydrogenase E1 β subunit |
| Q36579585 | Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases |
| Q42947662 | Abscisic Acid Increases Arabidopsis ABI5 Transcription Factor Levels by Promoting KEG E3 Ligase Self-Ubiquitination and Proteasomal Degradation |
| Q24301131 | Acetylation negatively regulates glycogen phosphorylase by recruiting protein phosphatase 1 |
| Q34283583 | Agnoprotein of mammalian polyomaviruses |
| Q49311835 | Akt regulates neurite growth by phosphorylation-dependent inhibition of radixin proteasomal degradation |
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| Q91859979 | An Advanced Strategy for Comprehensive Profiling of ADP-ribosylation Sites Using Mass Spectrometry-based Proteomics |
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| Q33859813 | An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes |
| Q39502343 | An acetylation switch regulates SUMO-dependent protein interaction networks. |
| Q28478315 | An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes |
| Q47407025 | An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1. |
| Q30157382 | An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment. |
| Q36506592 | An unusual two-step control of CPEB destruction by Pin1. |
| Q87317607 | Application guide for omics approaches to cell signaling |
| Q58055618 | Applications of Quantitative Proteomics in Plant Research |
| Q35111105 | Arabidopsis protein phosphatase DBP1 nucleates a protein network with a role in regulating plant defense |
| Q36583286 | Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models |
| Q47163267 | Automated visualization of rule-based models |
| Q50645188 | B-cell subsets, signaling and their roles in secretion of autoantibodies. |
| Q37686453 | BMI1, a new target of CK2α |
| Q26766507 | Bacteria-host relationship: ubiquitin ligases as weapons of invasion |
| Q26863733 | Bacterial effectors and their functions in the ubiquitin-proteasome system: insight from the modes of substrate recognition |
| Q38840787 | Baricitinib for the treatment of rheumatoid arthritis |
| Q24315023 | Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2 |
| Q47361697 | Beyond Deubiquitylation: USP30-Mediated Regulation of Mitochondrial Homeostasis |
| Q34099075 | Bioinformatic analysis and post-translational modification crosstalk prediction of lysine acetylation |
| Q42734421 | Bioinformatic and proteomic analysis of bulk histones reveals PTM crosstalk and chromatin features |
| Q46424417 | Bioinformatics Analysis of Functional Associations of PTMs. |
| Q38256377 | Border control: selectivity of chloroplast protein import and regulation at the TOC-complex. |
| Q33670087 | Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway |
| Q28131738 | Breaking the chains: structure and function of the deubiquitinases |
| Q57112840 | Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis |
| Q28116037 | CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome |
| Q24336920 | CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response |
| Q39076762 | CK2-An Emerging Target for Neurological and Psychiatric Disorders |
| Q42511084 | COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation |
| Q35627570 | CREB and leukemogenesis |
| Q41279491 | Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway. |
| Q92998218 | Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli |
| Q38022489 | Cell biology of vasopressin-regulated aquaporin-2 trafficking. |
| Q38380126 | Cell regulation by phosphotyrosine-targeted ubiquitin ligases |
| Q24598357 | Cell signaling by receptor tyrosine kinases |
| Q43243372 | Cells, shared memory and breaking the PTM code |
| Q33953067 | Cellular senescence and protein degradation: breaking down cancer |
| Q30313353 | Changes in PUB22 Ubiquitination Modes Triggered by MITOGEN-ACTIVATED PROTEIN KINASE3 Dampen the Immune Response. |
| Q38270797 | Characterization of human neural differentiation from pluripotent stem cells using proteomics/PTMomics--current state-of-the-art and challenges |
| Q30418482 | Characterizing ubiquitination sites by peptide-based immunoaffinity enrichment. |
| Q54172510 | Chemical JAK inhibitors for the treatment of rheumatoid arthritis. |
| Q35051327 | Circles within circles: crosstalk between protein Ser/Thr/Tyr-phosphorylation and Met oxidation |
| Q37611791 | Comparative Phosphoproteomic Analysis under High-Nitrogen Fertilizer Reveals Central Phosphoproteins Promoting Wheat Grain Starch and Protein Synthesis. |
| Q42735782 | Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions |
| Q90396755 | Comprehensive Phosphoproteomic Analysis of Pepper Fruit Development Provides Insight into Plant Signaling Transduction |
| Q37155474 | Control of alternative splicing by signal-dependent degradation of splicing-regulatory proteins |
| Q37864394 | Control of nuclear receptor activities in metabolism by post-translational modifications |
| Q39437743 | Conventional protein kinase C-α (PKC-α) and PKC-β negatively regulate RIG-I antiviral signal transduction |
| Q47159672 | Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins. |
| Q35971460 | Coordinate to guard: crosstalk of phosphorylation, sumoylation, and ubiquitylation in DNA damage response. |
| Q37171416 | Cracking the coregulator codes |
| Q37619779 | Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells |
| Q42265191 | Crosstalk and competition in signaling networks |
| Q104581362 | Crosstalk between Ubiquitination and Other Post-translational Protein Modifications in Plant Immunity |
| Q38496444 | Current status of the plant phosphorylation site database PhosPhAt and its use as a resource for molecular plant physiology |
| Q28085402 | Current strategies and findings in clinically relevant post-translational modification-specific proteomics |
| Q58696022 | Cyclin-dependent kinase modulates budding yeast Rad5 stability during cell cycle |
| Q42687789 | Cysteine S-linked N-acetylglucosamine (S-GlcNAcylation), A New Post-translational Modification in Mammals |
| Q35570971 | DHA reduces the atrophy-associated Fn14 protein in differentiated myotubes during coculture with macrophages. |
| Q36588889 | DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. |
| Q34326683 | DOK3 negatively regulates LPS responses and endotoxin tolerance |
| Q35788640 | DYRK2 Negatively Regulates Type I Interferon Induction by Promoting TBK1 Degradation via Ser527 Phosphorylation |
| Q55092857 | Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates. |
| Q36171164 | Deciphering a global network of functionally associated post-translational modifications |
| Q64989029 | Deciphering the SUMO code in the kidney. |
| Q37749492 | Decoding signalling networks by mass spectrometry-based proteomics |
| Q37690608 | Defining an Embedded Code for Protein Ubiquitination |
| Q30009269 | Defying c-Abl signaling circuits through small allosteric compounds |
| Q37419861 | Degradation of activated protein kinases by ubiquitination |
| Q33489621 | Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex |
| Q28748325 | Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons |
| Q47261894 | Degradation of the stress-responsive enzyme formate dehydrogenase by the RING-type E3 ligase Keep on Going and the ubiquitin 26S proteasome system |
| Q34979900 | Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression |
| Q36189503 | Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation |
| Q38724758 | Design Principles Involving Protein Disorder Facilitate Specific Substrate Selection and Degradation by the Ubiquitin-Proteasome System. |
| Q30872503 | Deubiquitinase activities required for hepatocyte growth factor-induced scattering of epithelial cells |
| Q58774942 | Deubiquitinase inhibitor PR-619 reduces Smad4 expression and suppresses renal fibrosis in mice with unilateral ureteral obstruction |
| Q38125278 | Deubiquitylases from genes to organism |
| Q38727716 | Direct Monitoring of Protein O-GlcNAcylation by High-Resolution Native Mass Spectrometry |
| Q39252412 | Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15. |
| Q24607508 | Discovery of cellular regulation by protein degradation |
| Q55218904 | Dissecting Structure-Encoded Determinants of Allosteric Cross-Talk between Post-Translational Modification Sites in the Hsp90 Chaperones. |
| Q54116010 | Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. |
| Q36666948 | ERα Mediates Estrogen-Induced Expression of the Breast Cancer Metastasis Suppressor Gene BRMS1. |
| Q89744258 | Effect of Phosphorylation and O-GlcNAcylation on Proline-Rich Domains of Tau |
| Q38219824 | Emerging mechanisms of mRNP remodeling regulation |
| Q99593495 | Endocytosis of BRASSINOSTEROID INSENSITIVE1 is Partly Driven by a Canonical Tyrosine-based Motif |
| Q33676492 | Engram formation in psychiatric disorders |
| Q37827073 | Enigmatic MYC Conducts an Unfolding Systems Biology Symphony. |
| Q34119706 | Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D |
| Q57578354 | Evolutionary Divergent Suppressor Mutations in Conformational Diseases |
| Q98893655 | Examining the role of phosphorylation of p19INK4d in its stability and ubiquitination using chemical protein synthesis |
| Q26798369 | Expanding the ubiquitin code through post-translational modification |
| Q27319675 | Expression Atlas of the Deubiquitinating Enzymes in the Adult Mouse Retina, Their Evolutionary Diversification and Phenotypic Roles |
| Q49887971 | Expression, regulation and targeting of receptor tyrosine kinases in esophageal squamous cell carcinoma. |
| Q34281873 | Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling |
| Q33985330 | F-box only protein 31 (FBXO31) negatively regulates p38 mitogen-activated protein kinase (MAPK) signaling by mediating lysine 48-linked ubiquitination and degradation of mitogen-activated protein kinase kinase 6 (MKK6) |
| Q35801606 | FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway |
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| Q46089793 | Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma |
| Q24656983 | Fed-state clamp stimulates cellular mechanisms of muscle protein anabolism and modulates glucose disposal in normal men |
| Q42812712 | Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1. |
| Q38832210 | First Comprehensive Proteome Analyses of Lysine Acetylation and Succinylation in Seedling Leaves of Brachypodium distachyon L. |
| Q28117202 | Foxp3 protein stability is regulated by cyclin-dependent kinase 2 |
| Q36895438 | Frequent mutations in acetylation and ubiquitination sites suggest novel driver mechanisms of cancer |
| Q37065962 | Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18. |
| Q34361027 | Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttling |
| Q37770069 | Functional analysis of proteins and protein species using shotgun proteomics and linear mathematics |
| Q33804324 | GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation. |
| Q64108794 | GSK3β-SCFFBXW7α mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover |
| Q34479638 | Gains of ubiquitylation sites in highly conserved proteins in the human lineage. |
| Q88230574 | Getting the Message? Native Reactive Electrophiles Pass Two Out of Three Thresholds to be Bona Fide Signaling Mediators |
| Q28540007 | Global analysis of lysine acetylation suggests the involvement of protein acetylation in diverse biological processes in rice (Oryza sativa) |
| Q37404493 | Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation |
| Q28594444 | Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse |
| Q39920489 | Global protein stability profiling in mammalian cells |
| Q47548136 | Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores |
| Q36994922 | Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles. |
| Q54978761 | Glycogen synthase kinase-3 (Gsk-3) activity regulates mRNA methylation in mouse embryonic stem cells. |
| Q49538387 | Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination |
| Q24297641 | HAUSP, a novel deubiquitinase for Rb - MDM2 the critical regulator |
| Q92483766 | HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma |
| Q50281812 | Hakai overexpression effectively induces tumour progression and metastasis in vivo. |
| Q33931136 | High mobility group nucleosomal binding domain 2 (HMGN2) SUMOylation by the SUMO E3 ligase PIAS1 decreases the binding affinity to nucleosome core particles. |
| Q42051422 | Highly homologous eEF1A1 and eEF1A2 exhibit differential post-translational modification with significant enrichment around localised sites of sequence variation |
| Q38156859 | Human T-lymphotropic virus proteins and post-translational modification pathways |
| Q38701042 | Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line |
| Q37302745 | IAP-targeted therapies for cancer |
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| Q28475942 | Identification and characterization of a leucine-rich repeat kinase 2 (LRRK2) consensus phosphorylation motif |
| Q40748186 | Identification and functional characterization of polo-like kinase 2 autoregulatory sites |
| Q92192870 | Identification of Posttranslational Modifications (PTMs) of Proteins by Mass Spectrometry |
| Q91594882 | Identification of a novel EphB4 phosphodegron regulated by the autocrine IGFII/IRA axis in malignant mesothelioma |
| Q51836189 | Identification of a protein network interacting with TdRF1, a wheat RING ubiquitin ligase with a protective role against cellular dehydration. |
| Q47150016 | Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry |
| Q45387444 | Identification of the immediate-early genes of white spot syndrome virus |
| Q42542433 | Immune receptor signaling: from ubiquitination to NF-κB activation |
| Q33529063 | Immunohistochemistry in diagnostic surgical pathology: contributions of protein life-cycle, use of evidence-based methods and data normalization on interpretation of immunohistochemical stains. |
| Q39147209 | Import of Soluble Proteins into Chloroplasts and Potential Regulatory Mechanisms |
| Q33997488 | In silico analysis of protein Lys-N(𝜀)-acetylation in plants |
| Q45073732 | Inhibition of O-GlcNAcase sensitizes apoptosis and reverses bortezomib resistance in mantle cell lymphoma through modification of truncated Bid. |
| Q38420727 | Inhibition of protein-tyrosine phosphatase 1B (PTP1B) mediates ubiquitination and degradation of Bcr-Abl protein. |
| Q37618636 | Integrated proteomic analysis of post-translational modifications by serial enrichment. |
| Q38598015 | Integrating multiple signals into cell decisions by networks of protein modification cycles |
| Q34377093 | Integrating phosphoproteomics in systems biology |
| Q53163730 | Interacting factors and cellular localization of SR protein-specific kinase Dsk1. |
| Q40381336 | Interaction of Mal de Río Cuarto virus (Fijivirus genus) proteins and identification of putative factors determining viroplasm formation and decay. |
| Q55419599 | JNK-mediated microglial DICER degradation potentiates inflammatory responses to induce dopaminergic neuron loss. |
| Q26865446 | Janus kinase inhibitors in autoimmune diseases |
| Q34472177 | L-carnitine is an endogenous HDAC inhibitor selectively inhibiting cancer cell growth in vivo and in vitro |
| Q41785779 | LRRK2 dephosphorylation increases its ubiquitination |
| Q90093315 | Label-free quantitative identification of abnormally ubiquitinated proteins as useful biomarkers for human lung squamous cell carcinomas |
| Q33850670 | Large scale analysis of co-existing post-translational modifications in histone tails reveals global fine structure of cross-talk |
| Q48606333 | Large-scale analysis of posttranslational modifications in the hippocampus of patients with Alzheimer's disease using pI shift and label-free quantification without enrichment |
| Q62662741 | Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase |
| Q37286921 | Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis |
| Q33752644 | Light-induced phosphorylation of crystallins in the retinal pigment epithelium |
| Q38604840 | Lighting Up T Lymphocyte Signaling with Quantitative Phosphoproteomics. |
| Q33940384 | Lysine methylation promotes VEGFR-2 activation and angiogenesis |
| Q37447667 | MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch |
| Q35668729 | Makorin ring zinc finger protein 1 (MKRN1), a novel poly(A)-binding protein-interacting protein, stimulates translation in nerve cells |
| Q34298055 | Mapping the stabilome: a novel computational method for classifying metabolic protein stability |
| Q38222148 | Mass spectrometric analysis of post-translational modifications (PTMs) and protein-protein interactions (PPIs). |
| Q27001576 | Mass spectrometry-based detection and assignment of protein posttranslational modifications |
| Q38217990 | Mass spectrometry-driven phosphoproteomics: patterning the systems biology mosaic |
| Q36135254 | Mechanistic insights into the regulation of metabolic enzymes by acetylation |
| Q35879654 | Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen |
| Q41352354 | Methionine residues around phosphorylation sites are preferentially oxidized in vivo under stress conditions |
| Q34624932 | Microbial signature-triggered plant defense responses and early signaling mechanisms |
| Q37346842 | Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility |
| Q39103838 | Mitotic phosphotyrosine network analysis reveals that tyrosine phosphorylation regulates Polo-like kinase 1 (PLK1). |
| Q52651882 | Modeling evolution of crosstalk in noisy signal transduction networks. |
| Q36153880 | Modular evolution of phosphorylation-based signalling systems |
| Q51112320 | Molecular Biology of Aquaporins. |
| Q38167994 | Molecular mechanisms of SH2- and PTB-domain-containing proteins in receptor tyrosine kinase signaling |
| Q38315883 | Multifaceted role of the ubiquitin ligase Itch in immune regulation |
| Q38773802 | Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking |
| Q44129459 | Multisite light-induced phosphorylation of the transcription factor PIF3 is necessary for both its rapid degradation and concomitant negative feedback modulation of photoreceptor phyB levels in Arabidopsis |
| Q33778197 | Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation |
| Q41717221 | Mutation of the highly conserved Ser-40 of the HIV-1 p6 gag protein to Phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of Gag. |
| Q24304067 | Mutations in SOX17 are associated with congenital anomalies of the kidney and the urinary tract |
| Q28513218 | Nek1 and TAZ interact to maintain normal levels of polycystin 2 |
| Q92731864 | Nitration-induced ubiquitination and degradation control quality of ERK1 |
| Q55262573 | Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. |
| Q39710300 | Nitrogen Starvation-induced Phosphorylation of Ras1 Protein and Its Potential Role in Nutrient Signaling and Stress Response. |
| Q37556159 | Noncanonical K27-linked polyubiquitination of TIEG1 regulates Foxp3 expression and tumor growth. |
| Q36162600 | Nonsynonymous Single-Nucleotide Variations on Some Posttranslational Modifications of Human Proteins and the Association with Diseases |
| Q54980192 | Nuclear Signaling of Plant MAPKs. |
| Q35096609 | Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation |
| Q64446520 | Orchestrating the proteome with post-translational modifications |
| Q83171482 | Origins of regulated cell-to-cell variability |
| Q36362827 | Oxidative stress responses involve oxidation of a conserved ubiquitin pathway enzyme |
| Q42321011 | PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival. |
| Q24652618 | PKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitination |
| Q24651948 | PKCdelta regulates cortical radial migration by stabilizing the Cdk5 activator p35 |
| Q90703886 | PTEN-GSK3β-MOB1 axis controls neurite outgrowth in vitro and in vivo |
| Q43214954 | PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins |
| Q36491375 | PTMcode: a database of known and predicted functional associations between post-translational modifications in proteins |
| Q37863593 | PTMs in conversation: activity and function of deubiquitinating enzymes regulated via post-translational modifications |
| Q89017100 | PTMscape: an open source tool to predict generic post-translational modifications and map modification crosstalk in protein domains and biological processes |
| Q37728924 | Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance |
| Q35107334 | Phosphatase specificity and pathway insulation in signaling networks |
| Q39434337 | Phosphoproteomic studies of receptor tyrosine kinases: future perspectives |
| Q38747840 | Phosphorylation Impacts N-end Rule Degradation of the Proteolytically Activated Form of BMX Kinase |
| Q92800172 | Phosphorylation Status of Tyrosine 78 Residue Regulates the Nuclear Export and Ubiquitination of Influenza A Virus Nucleoprotein |
| Q24310482 | Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate |
| Q34355799 | Phosphorylation by casein kinase 2 facilitates Psh1 protein-assisted degradation of Cse4 protein |
| Q37483222 | Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile |
| Q35970651 | Phosphorylation of intrinsically disordered regions in remorin proteins |
| Q33966907 | Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry |
| Q47322523 | Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase |
| Q28588118 | Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination |
| Q33800071 | Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding |
| Q38216962 | Phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins. |
| Q48000481 | Phosphorylation-dependent signaling controls degradation of DNA mismatch repair protein PMS2. |
| Q39609052 | Phosphorylation-mediated negative regulation of RIG-I antiviral activity |
| Q35865778 | Polyubiquitination of Transforming Growth Factor β-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4-mediated JNK and p38 MAPK Activation |
| Q39458884 | Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation |
| Q52668677 | Porcine MKRN1 modulates the replication and pathogenesis of PCV2 by inducing capsid protein ubiquitination and degradation. |
| Q95272429 | Post-translational Modification Crosstalk and Hotspots in Sirtuin Interactors Implicated in Cardiovascular Diseases |
| Q57116377 | Post-translational modifications of transporters |
| Q39458855 | Post-translational regulation of antiviral innate signaling. |
| Q37559665 | Post-translational regulation of inflammasomes |
| Q38074944 | Posttranslational modification and quality control. |
| Q37377433 | Posttranslational modifications of PPAR-gamma: fine-tuning the metabolic master regulator |
| Q88487488 | Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way |
| Q33381458 | Predicting protein post-translational modifications using meta-analysis of proteome scale data sets |
| Q26781745 | Progress in epigenetic histone modification analysis by mass spectrometry for clinical investigations |
| Q38851433 | Progress in understanding the safety and efficacy of Janus kinase inhibitors for treatment of rheumatoid arthritis |
| Q46295832 | Proteasome-independent polyubiquitin linkage regulates synapse scaffolding, efficacy, and plasticity. |
| Q38777113 | Protein kinase CK2 modulates HSJ1 function through phosphorylation of the UIM2 domain |
| Q24321736 | Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase |
| Q24632495 | Protein phosphatases and Alzheimer's disease |
| Q30390999 | Proteome-wide survey of phosphorylation patterns affected by nuclear DNA polymorphisms in Arabidopsis thaliana |
| Q24337180 | Proteomic identification of Hsp70 as a new Plk1 substrate in arsenic trioxide-induced mitotically arrested cells |
| Q34627238 | Proteomic snapshot of the EGF-induced ubiquitin network |
| Q38761409 | Proteomic studies associated with Parkinson's disease. |
| Q37676851 | Proteomics insights into DNA damage response and translating this knowledge to clinical strategies |
| Q42092143 | Pulling a Ligase out of a "HAT": pCAF Mediates Ubiquitination of the Class II Transactivator. |
| Q35747225 | Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications |
| Q26823466 | Quantifying ubiquitin signaling |
| Q90071388 | Quantitation of Single and Combinatorial Histone Modifications by Integrated Chromatography of Bottom-up Peptides and Middle-down Polypeptide Tails |
| Q43055809 | Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks. |
| Q30375585 | Quantitative proteomic analysis of histone modifications |
| Q34622632 | Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. |
| Q39907130 | Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression |
| Q33891413 | Quantitative, high-resolution proteomics for data-driven systems biology |
| Q38062297 | RNA metabolism and ubiquitin/ubiquitin-like modifications collide. |
| Q24299327 | RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling |
| Q52347159 | RSK2 is required for TRAF6 phosphorylation-mediated colon inflammation. |
| Q44802504 | RUBI: rapid proteomic-scale prediction of lysine ubiquitination and factors influencing predictor performance. |
| Q38941577 | Recent Progress in JAK Inhibitors for the Treatment of Rheumatoid Arthritis |
| Q47672478 | Recent advances in phosphoproteomics and application to neurological diseases |
| Q61796566 | Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors |
| Q26781752 | Recent findings and technological advances in phosphoproteomics for cells and tissues |
| Q64970839 | Reciprocal action of Casein Kinase Iε on core planar polarity proteins regulates clustering and asymmetric localisation. |
| Q37410758 | Regulating the activity of class II transactivator by posttranslational modifications: exploring the possibilities |
| Q39621322 | Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination. |
| Q49025789 | Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination |
| Q33521907 | Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation. |
| Q26830449 | Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination |
| Q38193259 | Regulation of Wnt/β-catenin signaling by posttranslational modifications |
| Q91950690 | Regulation of inner nuclear membrane associated protein degradation |
| Q37039478 | Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway |
| Q38119185 | Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination |
| Q91970788 | Regulation of reactive oxygen species during plant immunity through phosphorylation and ubiquitination of RBOHD |
| Q30492045 | Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II. |
| Q34627384 | Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications. |
| Q37249768 | Rewiring MAP kinases in Saccharomyces cerevisiae to regulate novel targets through ubiquitination |
| Q37608589 | Role of extracellular signal-regulated kinase 5 in adipocyte signaling |
| Q35107707 | Role of ubiquitination in Na,K-ATPase regulation during lung injury |
| Q39446383 | Roles of four Arabidopsis U-box E3 ubiquitin ligases in negative regulation of abscisic acid-mediated drought stress responses |
| Q37713589 | S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development |
| Q37765014 | SAMPyling proteins in archaea |
| Q34683293 | SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1) |
| Q36504487 | SCG10 is a JNK target in the axonal degeneration pathway. |
| Q64389473 | SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair |
| Q30355064 | Serine 421 regulates mutant huntingtin toxicity and clearance in mice. |
| Q36002714 | Single-step inline hydroxyapatite enrichment facilitates identification and quantitation of phosphopeptides from mass-limited proteomes with MudPIT |
| Q38760408 | Site-specific Disruption of the Oct4/Sox2 Protein Interaction Reveals Coordinated Mesendodermal Differentiation and the Epithelial-Mesenchymal Transition |
| Q37392596 | Small ubiquitin-like modifiers in cellular malignancy and metastasis |
| Q50350473 | Src Acts as an Effector for Ku70-dependent Suppression of Apoptosis through Phosphorylation of Ku70 at Tyr-530. |
| Q53516540 | Src inhibitors modulate frataxin protein levels. |
| Q99571780 | Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases |
| Q47619828 | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. |
| Q35232590 | Suberoylanilide hydroxamic acid treatment reveals crosstalks among proteome, ubiquitylome and acetylome in non-small cell lung cancer A549 cell line |
| Q57284404 | Substrate priming enhances phosphorylation by the budding yeast kinases Kin1 and Kin2 |
| Q34968474 | Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase |
| Q34055928 | Sumoylation of bZIP transcription factor NRL modulates target gene expression during photoreceptor differentiation. |
| Q39090269 | Suppression of Arabidopsis AtPUB30 resulted in increased tolerance to salt stress during germination |
| Q36265479 | Systematic Analysis and Prediction of In Situ Cross Talk of O-GlcNAcylation and Phosphorylation. |
| Q35148418 | Systematic characterization and prediction of post-translational modification cross-talk. |
| Q27936051 | Systematic functional prioritization of protein posttranslational modifications |
| Q39682740 | Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation |
| Q37461017 | Systems biology and heart failure: concepts, methods, and potential research applications |
| Q83202651 | T-cell signaling and immunopathologies |
| Q90083267 | TGF-β signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity |
| Q39949585 | TRAF6 and the three C-terminal lysine sites on IRF7 are required for its ubiquitination-mediated activation by the tumor necrosis factor receptor family member latent membrane protein 1 |
| Q97643137 | TRIB3-EGFR interaction promotes lung cancer progression and defines a therapeutic target |
| Q80895558 | TRIM-ing down Tolls |
| Q37618680 | TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η. |
| Q37350145 | Talking to chromatin: post-translational modulation of polycomb group function. |
| Q30424053 | Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets |
| Q38090668 | Targeting the unactivated conformations of protein kinases for small molecule drug discovery |
| Q38493634 | Temporal phases of long-term potentiation (LTP): myth or fact? |
| Q39416205 | The Arabidopsis C3H2C3-Type RING E3 Ubiquitin Ligase AtAIRP1 Is a Positive Regulator of an Abscisic Acid-Dependent Response to Drought Stress |
| Q38945356 | The Arabidopsis RING E3 ubiquitin ligase AtAIRP2 plays combinatory roles with AtAIRP1 in abscisic acid-mediated drought stress responses |
| Q36449307 | The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance. |
| Q40497616 | The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover |
| Q24294452 | The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt |
| Q90662134 | The E3 ubiquitin ligase Pib1 regulates effective gluconeogenic shutdown upon glucose availability |
| Q24314976 | The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation |
| Q35400332 | The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling |
| Q53570311 | The F-box protein Fbp1 functions in the invasive growth and cell wall integrity mitogen-activated protein kinase (MAPK) pathways in Fusarium oxysporum. |
| Q39268583 | The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97. |
| Q37742922 | The Kinase Activity of Calcineurin B-like Interacting Protein Kinase 26 (CIPK26) Influences Its Own Stability and that of the ABA-regulated Ubiquitin Ligase, Keep on Going (KEG). |
| Q92192864 | The Methods Employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein-Protein Interactions (PPIs) |
| Q47739019 | The RING-Type E3 Ligase XBAT35.2 Is Involved in Cell Death Induction and Pathogen Response. |
| Q47095192 | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. |
| Q102054019 | The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response |
| Q45373236 | The Ubiquitin-Proteasome System Regulates the Accumulation ofTurnip yellow mosaic virusRNA-Dependent RNA Polymerase during Viral Infection |
| Q26767879 | The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord Injury |
| Q41472998 | The awakening of the CDK10/Cyclin M protein kinase |
| Q35376123 | The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor α protein |
| Q41880378 | The class II transactivator (CIITA) is regulated by post-translational modification cross-talk between ERK1/2 phosphorylation, mono-ubiquitination and Lys63 ubiquitination |
| Q30666963 | The coming of age of phosphoproteomics--from large data sets to inference of protein functions |
| Q37661538 | The crosstalk between physiology and circadian clock proteins |
| Q39401616 | The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review). |
| Q39443049 | The death effector domain-containing DEDD forms a complex with Akt and Hsp90, and supports their stability. |
| Q40116005 | The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3. |
| Q30356852 | The next level of complexity: crosstalk of posttranslational modifications. |
| Q42288809 | The non-canonical Wnt receptor Ryk regulates hematopoietic stem cell repopulation in part by controlling proliferation and apoptosis |
| Q33965955 | The origin and early evolution of eukaryotes in the light of phylogenomics |
| Q43242860 | The p38 mitogen-activated protein kinase augments nucleotide excision repair by mediating DDB2 degradation and chromatin relaxation. |
| Q52577156 | The phosphorylated redox proteome of Chlamydomonas reinhardtii: Revealing novel means for regulation of protein structure and function. |
| Q37600107 | The rational parameterization theorem for multisite post-translational modification systems |
| Q33857612 | The regulation of TGF-β/SMAD signaling by protein deubiquitination |
| Q41961959 | The role of SUMO-1 in cardiac oxidative stress and hypertrophy. |
| Q37117060 | The role of protein phosphatase 4 in regulating microtubule severing in the Caenorhabditis elegans embryo |
| Q37381217 | The role of the ubiquitin proteasome system in ischemia and ischemic tolerance |
| Q90093670 | The role of ubiquitination in tumorigenesis and targeted drug discovery |
| Q28543485 | The roles of post-translational modifications in the context of protein interaction networks |
| Q44549934 | The switches.ELM resource: a compendium of conditional regulatory interaction interfaces |
| Q41911751 | The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation |
| Q24322642 | The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling |
| Q37143739 | The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X |
| Q37425595 | The ubiquitin landscape at DNA double-strand breaks |
| Q38905767 | Top-down Proteomics: Technology Advancements and Applications to Heart Diseases. |
| Q30394774 | Towards understanding the crosstalk between protein post-translational modifications: Homo- and heterotypic PTM pair distances on protein surfaces are not random |
| Q26741924 | Transcriptional regulation by complex interplay between post-translational modifications |
| Q34546438 | Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease |
| Q43065281 | Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system. |
| Q36832181 | Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation |
| Q38743981 | Tyrosine phosphorylation modulates mitochondrial chaperonin Hsp60 and delays rotavirus NSP4-mediated apoptotic signaling in host cells |
| Q39791635 | Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin-proteasome pathway |
| Q47935968 | ULK1 ubiquitylation is regulated by phosphorylation on its carboxy terminus |
| Q30010083 | Ubiquitin and its binding domains. |
| Q92128904 | Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells |
| Q34539820 | Ubiquitin makes its mark on immune regulation |
| Q37302762 | Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction |
| Q30497896 | Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility. |
| Q42033458 | Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1 |
| Q36228675 | Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family |
| Q35674976 | Ubiquitin-specific proteases are differentially expressed throughout the Schistosoma mansoni life cycle. |
| Q34284293 | Ubiquitination of pattern recognition receptors in plant innate immunity |
| Q34439487 | Understanding the acetylome: translating targeted proteomics into meaningful physiology |
| Q40204933 | Unlimited multistability in multisite phosphorylation systems |
| Q38047273 | Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomics. |
| Q49826920 | Utilizing a Comprehensive Immunoprecipitation Enrichment System to Identify an Endogenous Post-translational Modification Profile for Target Proteins |
| Q34360923 | When ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling |
| Q38073986 | Why nature really chose phosphate |
| Q37683401 | Yeast Pah1p phosphatidate phosphatase is regulated by proteasome-mediated degradation. |
| Q33403403 | Zyxin is a novel interacting partner for SIRT1 |
| Q28306984 | betaTrCP- and Rsk1/2-mediated degradation of BimEL inhibits apoptosis |
| Q28251047 | mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR |
| Q39660793 | p300-Mediated Acetylation Stabilizes the Th-Inducing POK Factor |
| Q64069886 | p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity |
| Q35604861 | γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. |
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