LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis

scientific article published on 17 June 2013

LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.00105-13
P932PMC publication ID3753919
P698PubMed publication ID23775124

P50authorMustapha Si-TaharQ40037871
Catherine WertsQ92157279
P2093author name stringFany Blanc
Yann Nouët
Stefano Cairo
Ju Chen
Minou Adib-Conquy
Yu Wei
Grégory Jouvion
Ali Tebbi
Thierry Tordjmann
Jennifer Dahan
Marie-Annick Buendia
Florence Levillayer
Anne-Marie Cassard-Doulcier
Lauriane Remy
P2860cites workFHL2 (SLIM3) is not essential for cardiac development and functionQ39455832
The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation.Q39996662
Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-cateninQ40486121
Depressed liver regeneration after partial hepatectomy of germ-free, athymic and lipopolysaccharide-resistant miceQ41204512
Hypothalamic vasopressin release and hepatocyte Ca 2+ signaling during liver regeneration: an interplay stimulating liver growth and bile flowQ44602920
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesisQ46576855
Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivoQ48000638
The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis.Q53267726
Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular CarcinomaQ58619568
A rat fatty liver transplant modelQ70665158
Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammationQ71832696
Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4Q74261317
Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitisQ83679148
SKI activates Wnt/beta-catenin signaling in human melanomaQ24298640
FHL2, a novel tissue-specific coactivator of the androgen receptorQ24601620
Tumor necrosis factor receptor-associated factor 6 is an intranuclear transcriptional coactivator in osteoclastsQ24651323
NF-κB, the first quarter-century: remarkable progress and outstanding questionsQ26822516
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chainQ28142613
Identification of the LIM protein FHL2 as a coactivator of beta-cateninQ28216665
Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κBQ28508403
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 productionQ29614596
NF-kappaB functions as a tumour promoter in inflammation-associated cancerQ29614598
Ubiquitin signalling in the NF-kappaB pathwayQ29616322
The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblastsQ31113643
FHL2, UBC9, and PIAS1 are novel estrogen receptor alpha-interacting proteinsQ33211123
TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation.Q33292102
Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activationQ33737707
The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complexQ33748985
Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant miceQ33815903
FHL2 inhibits the activated osteoclast in a TRAF6-dependent mannerQ34014506
The LIM-only protein FHL2 is a serum-inducible transcriptional coactivator of AP-1.Q34184539
Liver regeneration: from myth to mechanismQ34354926
Liver regeneration. 2. Role of growth factors and cytokines in hepatic regenerationQ34368036
The multifunctional roles of the four-and-a-half-LIM only protein FHL2.Q34481193
NF-κB and STAT3 - key players in liver inflammation and cancerQ35347976
Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1Q35838885
IKK biologyQ35848596
The four and a half LIM-only protein 2 (FHL2) activates transforming growth factor β (TGF-β) signaling by regulating ubiquitination of the E3 ligase Arkadia.Q36543763
Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway.Q37073709
NF-kappaB signaling, liver disease and hepatoprotective agentsQ37302741
Hierarchies of NF-κB target-gene regulationQ37902866
Inhibition of PP1 phosphatase activity by HBx: a mechanism for the activation of hepatitis B virus transcriptionQ38329033
The LIM-only protein FHL2 controls mesenchymal cell osteogenic differentiation and bone formation through Wnt5a and Wnt10bQ39234696
The LIM-only protein FHL2 regulates interleukin-6 expression through p38 MAPK mediated NF-κB pathway in muscle cellsQ39341942
P4510describes a project that usesImageJQ1659584
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)3299-3308
P577publication date2013-06-17
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleLIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis
P478volume33

Reverse relations

cites work (P2860)
Q41182528Autophagy Induced FHL2 Upregulation Promotes IL-6 Production by Activating the NF-κB Pathway in Mouse Aortic Endothelial Cells after Exposure to PM2.5.
Q51608667Deficiency of FHL2 attenuates airway inflammation in mice and genetic variation associates with human bronchial hyper-responsiveness.
Q36429362Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress
Q33991611Differences in the expression of chromosome 1 genes between lung telocytes and other cells: mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells and lymphocytes
Q55457293Differential Effects of Estrogen Receptor β Isoforms on Glioblastoma Progression.
Q37637908FHL2 Regulates Natural Killer Cell Development and Activation during Streptococcus pneumoniae Infection
Q47871595FHL2 interacts with EGFR to promote glioblastoma growth
Q35137904FHL2 regulates hematopoietic stem cell functions under stress conditions
Q92814967Four-And-A-Half LIM-Domain Protein 2 (FHL2) Deficiency Aggravates Cholestatic Liver Injury
Q34411166Identification of gene regulation patterns underlying both oestrogen- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells.
Q40324906LIM-Only Protein FHL2 Is a Negative Regulator of Transforming Growth Factor β1 Expression
Q92185461LIM-only protein FHL2 attenuates inflammation in vascular smooth muscle cells through inhibition of the NFκB pathway
Q40614757LIM-only protein FHL2 regulates experimental pulmonary Schistosoma mansoni egg granuloma formation
Q41684152Molecular Analysis of a Short-term Model of β-Glucans-Trained Immunity Highlights the Accessory Contribution of GM-CSF in Priming Mouse Macrophages Response.
Q58699735PARP12 (ARTD12) suppresses hepatocellular carcinoma metastasis through interacting with FHL2 and regulating its stability
Q37225511Small ubiquitin-related modifier 1 is involved in hepatocellular carcinoma progression via mediating p65 nuclear translocation
Q33870920The Enterococcus faecalis virulence factor ElrA interacts with the human Four-and-a-Half LIM Domains Protein 2
Q27301282The LIM-only protein FHL2 attenuates lung inflammation during bleomycin-induced fibrosis
Q21132015Transcriptional regulation of the tumor suppressor FHL2 by p53 in human kidney and liver cells

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