PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1-Xbp1s pathway expedites liver injury.

scientific article published on 12 May 2015

PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1-Xbp1s pathway expedites liver injury. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/GUTJNL-2014-308506
P932PMC publication ID4975835
P698PubMed publication ID25966993
P5875ResearchGate publication ID276295863

P50authorJa Hyun KooQ83804100
P2093author name stringWon Kim
Sang Geon Kim
Sang Woo Lim
Chang Yeob Han
P2860cites workRegulation of apoptosis by endoplasmic reticulum pathways.Q35591699
Endoplasmic reticulum stress in liver diseaseQ36031838
Clinical use of albumin in hepatologyQ37655017
Modulating stress responses by the UPRosome: a matter of life and deathQ37863862
Role of endoplasmic reticulum stress in metabolic disease and other disorders.Q37976132
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.Q39299575
The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survivalQ39467135
Serum-withdrawal-dependent apoptosis of hippocampal neuroblasts involves Ca++ release by endoplasmic reticulum and caspase-12 activationQ40151515
LPA rescues ER stress-associated apoptosis in hypoxia and serum deprivation-stimulated mesenchymal stem cellsQ43038790
Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injuryQ43823642
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C.Q44332232
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-IIQ81144490
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factorQ24292102
The unfolded protein response: integrating stress signals through the stress sensor IRE1αQ24293771
Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53Q24300781
PH domain-only protein PHLDA3 is a p53-regulated repressor of AktQ24309413
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosisQ24554008
AKT/PKB signaling: navigating downstreamQ24657857
Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein responseQ28139950
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein ResponseQ28585314
The unfolded protein response: controlling cell fate decisions under ER stress and beyondQ29615499
IRE1 signaling affects cell fate during the unfolded protein responseQ29615502
ER stress triggers apoptosis by activating BH3-only protein BimQ29617730
BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosisQ29620466
Physiological regulation of Akt activity and stability.Q33680673
PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumorsQ33767655
Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatinQ34501203
Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53Q34812489
The contribution of endoplasmic reticulum stress to liver diseasesQ34860549
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alphaQ34992544
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
overexpressionQ61643320
P1104number of pages12
P304page(s)1377-1388
P577publication date2015-05-12
P1433published inGutQ5621669
P1476titlePHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1-Xbp1s pathway expedites liver injury
P478volume65

Reverse relations

cites work (P2860)
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Q41207747β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis

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