Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity

scientific article published on December 2008

Destabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2008.10.014
P932PMC publication ID2671083
P698PubMed publication ID19081375
P5875ResearchGate publication ID23662201

P50authorRobert MalenkaQ16731868
Brian L CzervionkeQ125252025
Bernardo L. SabatiniQ29169188
P2093author name stringWeifeng Xu
Pascal Steiner
Michael J Higley
P2860cites workEnhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 proteinQ22008543
Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactinQ22010466
Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complexQ24306062
Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor numberQ24536358
Optical induction of plasticity at single synapses reveals input-specific accumulation of alphaCaMKIIQ24646556
Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spinesQ24677936
GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering moleculesQ24681609
Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent mannerQ24683943
Rapid redistribution of synaptic PSD-95 in the neocortex in vivoQ27335045
Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic densityQ28140303
The Shank family of scaffold proteinsQ28144084
The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42Q28181795
Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrinQ28213213
Identification of novel phosphorylation sites on postsynaptic density proteinsQ28281343
Transmitting on actin: synaptic control of dendritic architectureQ36704180
Spine expansion and stabilization associated with long-term potentiationQ36923761
Regulation of DLG localization at synapses by CaMKII-dependent phosphorylationQ42080193
Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression.Q42170154
Locally dynamic synaptic learning rules in pyramidal neuron dendritesQ42287800
Alternative N-terminal domains of PSD-95 and SAP97 govern activity-dependent regulation of synaptic AMPA receptor functionQ43506207
PSD-95 regulates synaptic transmission and plasticity in rat cerebral cortexQ44300300
Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons.Q44746561
Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity.Q44746570
The number of glutamate receptors opened by synaptic stimulation in single hippocampal spines.Q44777547
Persistent accumulation of calcium/calmodulin-dependent protein kinase II in dendritic spines after induction of NMDA receptor-dependent chemical long-term potentiation.Q45117194
Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactionsQ45123828
Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins.Q46305019
Quantitative ultrastructural analysis of hippocampal excitatory synapses.Q46681133
Neuronal activity regulates diffusion across the neck of dendritic spines.Q46792224
Homer1a regulates the activity-induced remodeling of synaptic structures in cultured hippocampal neuronsQ46898095
Postsynaptic protein mobility in dendritic spines: long-term regulation by synaptic NMDA receptor activationQ46965848
Continual remodeling of postsynaptic density and its regulation by synaptic activityQ48128407
Different modes of expression of AMPA and NMDA receptors in hippocampal synapsesQ48160411
Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization.Q48274256
Calcium-calmodulin-dependent protein kinase II phosphorylation modulates PSD-95 binding to NMDA receptorsQ48344083
Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampusQ48377872
Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II.Q52024852
Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristicsQ69702481
Investigation of protein substrates of Ca(2+)/calmodulin-dependent protein kinase II translocated to the postsynaptic densityQ72989273
SynGAP regulates spine formationQ28286604
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95Q28290055
An architectural framework that may lie at the core of the postsynaptic densityQ28293971
Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neuronsQ28363018
Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAPQ28565555
Selective regulation of neurite extension and synapse formation by the beta but not the alpha isoform of CaMKIIQ28571729
Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroliginQ28572335
Identification of protein substrates of Ca(2+)/calmodulin-dependent protein kinase II in the postsynaptic density by protein sequencing and mass spectrometryQ28574603
Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulationQ28575500
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2Q28578379
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesisQ28578820
Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank familyQ28579721
SPIN90/WISH interacts with PSD-95 and regulates dendritic spinogenesis via an N-WASP-independent mechanismQ28581312
cAMP-dependent protein kinase postsynaptic localization regulated by NMDA receptor activation through translocation of an A-kinase anchoring protein scaffold proteinQ28584074
Structural basis of long-term potentiation in single dendritic spinesQ29547598
A simple method for organotypic cultures of nervous tissueQ29614375
Shrinkage of dendritic spines associated with long-term depression of hippocampal synapsesQ29615872
PSD-95 involvement in maturation of excitatory synapsesQ29616167
PDZ domain proteins of synapsesQ29616399
Transient and persistent dendritic spines in the neocortex in vivoQ29618402
A photoactivatable GFP for selective photolabeling of proteins and cellsQ29620329
Regulation of dendritic spine morphology and synaptic function by Shank and HomerQ30014842
Analysis of calcium channels in single spines using optical fluctuation analysisQ30634619
Local sharing as a predominant determinant of synaptic matrix molecular dynamicsQ33253664
Developmental presence and disappearance of postsynaptically silent synapses on dendritic spines of rat layer 2/3 pyramidal neuronsQ33315224
Mass of the postsynaptic density and enumeration of three key moleculesQ33910509
Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusionQ33915353
Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines.Q34446029
Molecular dissociation of the role of PSD-95 in regulating synaptic strength and LTDQ35138226
PSD-95 is required for activity-driven synapse stabilizationQ35676844
The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structureQ35748629
Regulation of spine morphology and spine density by NMDA receptor signaling in vivoQ36288712
Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clusteringQ36301632
The postsynaptic densityQ36545830
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
synaptic plasticityQ1551556
P304page(s)788-802
P577publication date2008-12-01
P1433published inNeuronQ3338676
P1476titleDestabilization of the postsynaptic density by PSD-95 serine 73 phosphorylation inhibits spine growth and synaptic plasticity
P478volume60

Reverse relations

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