Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites

scientific article published on October 2013

Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/BJ20130378
P932PMC publication ID3778707
P698PubMed publication ID23863084
P5875ResearchGate publication ID249996248

P2093author name stringMichael Aregger
Victoria H Cowling
P2860cites workWhat messenger RNA capping tells us about eukaryotic evolution.Q55036001
5′-Terminal structure and mRNA stabilityQ59054157
Inhibitors of transcription such as 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole and isoquinoline sulfonamide derivatives (H-8 and H-7) promote dephosphorylation of the carboxyl-terminal domain of RNA polymerase II largest subunitQ71622259
RAM/Fam103a1 is required for mRNA cap methylationQ24297879
Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexesQ24323361
Human mRNA cap methyltransferase: alternative nuclear localization signal motifs ensure nuclear localization required for viabilityQ24519081
Regulation of mRNA cap methylationQ24644921
A function of yeast mRNA cap methyltransferase, Abd1, in transcription by RNA polymerase II.Q27931111
Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymesQ28144800
5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase IIQ28623635
Dynamic association of capping enzymes with transcribing RNA polymerase IIQ29614771
Progression through the RNA polymerase II CTD cycleQ29614782
Pre-mRNA processing reaches back to transcription and ahead to translationQ29615045
Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzymeQ33858428
RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes.Q34009055
Viral and cellular mRNA capping: past and prospectsQ34070118
Tat stimulates cotranscriptional capping of HIV mRNA.Q34156984
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stabilityQ36291314
TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeastQ37218934
Cap and cap-binding proteins in the control of gene expressionQ37940415
Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformationQ39774238
Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line.Q40758214
E2F1-dependent methyl cap formation requires RNA pol II phosphorylationQ42185668
Functional coupling of capping and transcription of mRNA.Q44199580
Capping of eucaryotic mRNAsQ44537736
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P1104number of pages7
P304page(s)67-73
P577publication date2013-10-01
P1433published inBiochemical JournalQ864221
P1476titleHuman cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites
P478volume455

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cites work (P2860)
Q38824694CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription.
Q111442247CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells
Q60541514DHX15 regulates CMTR1-dependent gene expression and cell proliferation
Q111442246Identification and Characterization of the Interaction Between the Methyl-7-Guanosine Cap Maturation Enzyme RNMT and the Cap-Binding Protein eIF4E
Q92435462Interplay of mRNA capping and transcription machineries
Q50327954MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-Catenin Signaling Transcripts By Recruiting CDK7 and RNA Methyltransferase
Q92075235Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: insights from accelerated molecular dynamics simulations
Q27719999Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Q38200434Myc and mRNA capping.
Q64106179Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells
Q39066290RAM function is dependent on Kapβ2-mediated nuclear entry
Q47102236RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs
Q43071071Regulation of mRNA capping in the cell cycle.
Q31131588Using RNA-Seq SNP data to reveal potential causal mutations related to pig production traits and RNA editing
Q42316813c-Myc deregulation induces mRNA capping enzyme dependency.
Q41786413mRNA Cap Methylation in Pluripotency and Differentiation
Q52714681mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription.
Q57479681mRNA cap regulation in mammalian cell function and fate
Q27469050mRNA capping: biological functions and applications

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