| scholarly article | Q13442814 |
| P2093 | author name string | Christopher M Cabello | |
| Georg T Wondrak | |||
| Sarah D Lamore | |||
| Shuxi Qiao | |||
| Jessica L Lesson | |||
| P2860 | cites work | The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis | Q22061955 |
| Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism | Q22251223 | ||
| Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53 | Q24300781 | ||
| Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib | Q24594790 | ||
| The topical antimicrobial zinc pyrithione is a heat shock response inducer that causes DNA damage and PARP-dependent energy crisis in human skin cells | Q24623981 | ||
| Redox-directed cancer therapeutics: molecular mechanisms and opportunities | Q24645584 | ||
| The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth | Q24646381 | ||
| Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1 | Q24655984 | ||
| Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum | Q24673769 | ||
| DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma | Q28297100 | ||
| N-Terminal dipeptides of D(-)-penicillamine as sequestration agents for acetaldehyde | Q28373125 | ||
| Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state | Q28572472 | ||
| The unfolded protein response: controlling cell fate decisions under ER stress and beyond | Q29615499 | ||
| Principles of cancer therapy: oncogene and non-oncogene addiction | Q29616779 | ||
| Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? | Q29616804 | ||
| ER stress triggers apoptosis by activating BH3-only protein Bim | Q29617730 | ||
| Angiostatin generating capacity and anti-tumour effects of D-penicillamine and plasminogen activators | Q33245745 | ||
| Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response | Q34236755 | ||
| Redox platforms in cancer drug discovery and development | Q34777711 | ||
| Mechanisms of resistance to RAF inhibitors in melanoma | Q35166950 | ||
| Ras, ROS and proteotoxic stress: a delicate balance | Q35230130 | ||
| Systematic review of medical treatment in melanoma: current status and future prospects. | Q35584299 | ||
| Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma | Q35800509 | ||
| Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes | Q35823218 | ||
| The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines | Q37130026 | ||
| Yeast flavin-containing monooxygenase is induced by the unfolded protein response | Q37143530 | ||
| Penicillamine therapy for pediatric cystinuria: experience from a cohort of American children. | Q37388421 | ||
| Targeting the endoplasmic reticulum-stress response as an anticancer strategy | Q37616303 | ||
| Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. | Q39676203 | ||
| Intracellular delivery of the reactive oxygen species generating agent D-penicillamine upon conjugation to poly-L-glutamic acid | Q39721523 | ||
| Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA. | Q39722836 | ||
| The protease inhibitor, elafin, induces p53-dependent apoptosis in human melanoma cells | Q39761600 | ||
| Bax inhibitor 1 regulates ER-stress-induced ROS accumulation through the regulation of cytochrome P450 2E1. | Q39865292 | ||
| NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis | Q40113045 | ||
| Penicillamine: Review and cutaneous manifestations | Q40114686 | ||
| An investigation into copper catalyzed D-penicillamine oxidation and subsequent hydrogen peroxide generation | Q40175338 | ||
| Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA. | Q40224015 | ||
| The metabolism and pharmacology of D-penicillamine in man. | Q40305924 | ||
| Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells | Q40310345 | ||
| Antimelanoma activity of apoptogenic carbonyl scavengers | Q40364786 | ||
| Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells | Q40396792 | ||
| Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine. | Q40745318 | ||
| Endogenous Noxa Determines the Strong Proapoptotic Synergism of the BH3-Mimetic ABT-737 with Chemotherapeutic Agents in Human Melanoma Cells. | Q42100332 | ||
| N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway | Q43282690 | ||
| Mechanisms for the cytotoxicity of cysteamine | Q43710220 | ||
| Single intratumoral injection of long-acting benzyl ester of D-penicillamine inhibits the growth of melanoma tumor in mice | Q44726214 | ||
| Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress | Q45712472 | ||
| Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress. | Q46431069 | ||
| Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. | Q46604669 | ||
| Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells | Q46983702 | ||
| Inhibition of the mitochondrial cyclosporin A-sensitive permeability transition pore by the arginine reagent phenylglyoxal. | Q53967923 | ||
| Wilson's disease | Q55880550 | ||
| Determination of the superoxide dismutating activity of D-penicillamine copper | Q67355056 | ||
| Microsomal mixed-function oxidase-dependent renaturation of reduced ribonuclease | Q67707927 | ||
| Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide | Q78195055 | ||
| P433 | issue | 10 | |
| P921 | main subject | D-penicillamine | Q421239 |
| metastatic melanoma | Q18975855 | ||
| P304 | page(s) | 1079-1094 | |
| P577 | publication date | 2012-10-01 | |
| P1433 | published in | Apoptosis | Q15749546 |
| P1476 | title | D-Penicillamine targets metastatic melanoma cells with induction of the unfolded protein response (UPR) and Noxa (PMAIP1)-dependent mitochondrial apoptosis | |
| P478 | volume | 17 |
| Q26778533 | Cancer Microenvironment and Endoplasmic Reticulum Stress Response |
| Q46387857 | D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H2O2-mediated oxidative stress. |
| Q51040011 | Hyperhomocysteinemia induces cardiac injury by up-regulation of p53-dependent Noxa and Bax expression through the p53 DNA methylation in ApoE(-/-) mice. |
| Q26765426 | Melanoma and the Unfolded Protein Response |
| Q38100669 | Penicillamine revisited: historic overview and review of the clinical uses and cutaneous adverse effects |
| Q36405689 | Protective Effects of D-Penicillamine on Catecholamine-Induced Myocardial Injury |
| Q40288832 | Reduction of Thrombosis and Bacterial Infection via Controlled Nitric Oxide (NO) Release from S-Nitroso-N-acetylpenicillamine (SNAP) Impregnated CarboSil Intravascular Catheters |
| Q35013756 | The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death |
| Q35121301 | The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells |
| Q36917366 | The role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: a double-edged sword of adaptation and apoptosis |
Search more.