| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/J.YJMCC.2009.02.001 |
| P8608 | Fatcat ID | release_sboxc2kdjza3vi4leqnpi6lkie |
| P932 | PMC publication ID | 2683201 |
| P698 | PubMed publication ID | 19217910 |
| P5875 | ResearchGate publication ID | 24011159 |
| P2093 | author name string | Michael N Sack | |
| P2860 | cites work | Estrogen-related receptor alpha directs peroxisome proliferator-activated receptor alpha signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle | Q24561461 |
| A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport | Q24603087 | ||
| Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes | Q24645537 | ||
| PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis | Q24798075 | ||
| Regulation of muscle fiber type and running endurance by PPARdelta | Q24799428 | ||
| Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
| Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification | Q27887261 | ||
| Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1 | Q28131760 | ||
| The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus | Q28190307 | ||
| The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity | Q28252642 | ||
| Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance | Q28253498 | ||
| Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha | Q28274682 | ||
| The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus | Q28344691 | ||
| Peroxisome proliferator-activated receptor delta (PPARdelta) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis | Q28572042 | ||
| Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose | Q28573520 | ||
| Therapeutic potential of resveratrol: the in vivo evidence | Q29547413 | ||
| Sirtuin activators mimic caloric restriction and delay ageing in metazoans | Q29547766 | ||
| Mitochondrial dysfunction and type 2 diabetes | Q29617913 | ||
| Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction | Q29618673 | ||
| A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis | Q29620243 | ||
| AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha | Q29620443 | ||
| Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway. | Q30359509 | ||
| Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35 years. | Q33545914 | ||
| Respiratory uncoupling induces delta-aminolevulinate synthase expression through a nuclear respiratory factor-1-dependent mechanism in HeLa cells. | Q33864490 | ||
| Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells | Q34122975 | ||
| New type of cardiomyopathy associated with diabetic glomerulosclerosis | Q34205051 | ||
| A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. | Q34330003 | ||
| An unexpected inverse relationship between HbA1c levels and mortality in patients with diabetes and advanced systolic heart failure | Q34478368 | ||
| Mitochondrial matrix phosphoproteome: effect of extra mitochondrial calcium | Q34483436 | ||
| Captopril normalizes insulin signaling and insulin-regulated substrate metabolism in obese (ob/ob) mouse hearts. | Q34591369 | ||
| Obesity and diabetes in the developing world--a growing challenge | Q34603178 | ||
| beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo independent of changes in malonyl-CoA content | Q44582169 | ||
| Impact of diabetes mellitus on long-term survival in patients with congestive heart failure. | Q44844669 | ||
| Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes | Q44865527 | ||
| Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts. | Q45032380 | ||
| Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation | Q46220928 | ||
| The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study | Q46576373 | ||
| The natural course of beta-cell function in nondiabetic and diabetic individuals: the Insulin Resistance Atherosclerosis Study | Q46605990 | ||
| Myocardial infarction and heart failure in the db/db diabetic mouse | Q46661270 | ||
| Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver | Q46670089 | ||
| Rosiglitazone treatment improves cardiac efficiency in hearts from diabetic mice. | Q46833709 | ||
| Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin | Q46835029 | ||
| Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. | Q46917083 | ||
| Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. | Q47286039 | ||
| Uncoupling proteins 2 and 3 function in concert to augment tolerance to cardiac ischemia | Q47752894 | ||
| Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle | Q47755014 | ||
| Tissue heterogeneity of the mammalian mitochondrial proteome | Q48439191 | ||
| The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms. | Q50714394 | ||
| Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse. | Q51775769 | ||
| Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. | Q53541654 | ||
| Abnormal function and glucose metabolism in the type-2 diabetic db/db mouse heart. | Q53566583 | ||
| CD36 Deficiency Rescues Lipotoxic Cardiomyopathy | Q57374829 | ||
| Echocardiographic evidence for the existence of a distinct diabetic cardiomyopathy (The Framingham Heart Study) | Q57604699 | ||
| Diastolic Stiffness of the Failing Diabetic Heart | Q58087772 | ||
| Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice | Q73127304 | ||
| Alteration in left ventricular diastolic filling and accumulation of myocardial collagen at insulin-resistant prediabetic stage of a type II diabetic rat model | Q73492545 | ||
| Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes | Q78060401 | ||
| Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy | Q79871363 | ||
| Statins for diabetic cardiovascular complications | Q79909755 | ||
| Calcium induces increases in peroxisome proliferator-activated receptor gamma coactivator-1alpha and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation | Q80292775 | ||
| Cardiac steatosis in diabetes mellitus: a 1H-magnetic resonance spectroscopy study | Q80795946 | ||
| Overexpression of mitochondrial transcription factor a ameliorates mitochondrial deficiencies and cardiac failure after myocardial infarction | Q80932637 | ||
| Cardiac hypertrophy caused by peroxisome proliferator- activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling | Q81152659 | ||
| Aging is associated with myocardial insulin resistance and mitochondrial dysfunction | Q81303058 | ||
| Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction | Q83861827 | ||
| Cardiovascular risk of rosiglitazone: another perspective | Q37322689 | ||
| Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. | Q37335886 | ||
| Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions | Q37486465 | ||
| Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis | Q37526796 | ||
| Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone | Q37591975 | ||
| Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals | Q37692490 | ||
| Leptin signalling reduces the severity of cardiac dysfunction and remodelling after chronic ischaemic injury. | Q38296419 | ||
| Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity | Q38319554 | ||
| Cardiac lipid accumulation associated with diastolic dysfunction in obese mice. | Q38352512 | ||
| Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. | Q38357891 | ||
| Why does diabetes increase atherosclerosis? I don't know! | Q39951404 | ||
| Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance | Q40028148 | ||
| Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells | Q40649634 | ||
| Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells | Q40879108 | ||
| Ketone bodies disturb fatty acid handling in isolated cardiomyocytes derived from control and diabetic rats | Q41817988 | ||
| Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart | Q42159479 | ||
| Increasing cardiovascular disease burden due to diabetes mellitus: the Framingham Heart Study | Q42165604 | ||
| Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man | Q42455774 | ||
| Sequential serum-dependent activation of CREB and NRF-1 leads to enhanced mitochondrial respiration through the induction of cytochrome c. | Q42802810 | ||
| Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues | Q43224134 | ||
| Effect of non-insulin-dependent diabetes mellitus on myocardial insulin responsiveness in patients with ischemic heart disease | Q43562630 | ||
| Hypoxia in vivo decreases peroxisome proliferator-activated receptor alpha-regulated gene expression in rat heart | Q43732000 | ||
| Diabetes mellitus prevents ischemic preconditioning in patients with a first acute anterior wall myocardial infarction | Q43754689 | ||
| The effect of diabetes mellitus on prognosis and serial left ventricular function after acute myocardial infarction: contribution of both coronary disease and diastolic left ventricular dysfunction to the adverse prognosis. The MILIS Study Group | Q43924876 | ||
| Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker Fatty rat heart. | Q43935460 | ||
| Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts | Q44071888 | ||
| Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice | Q44103922 | ||
| Proteome analysis reveals phosphorylation of ATP synthase beta -subunit in human skeletal muscle and proteins with potential roles in type 2 diabetes. | Q44280967 | ||
| Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice | Q44286385 | ||
| The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction | Q44472847 | ||
| Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes | Q44480693 | ||
| Ventricular remodeling does not accompany the development of heart failure in diabetic patients after myocardial infarction | Q44510886 | ||
| Rosiglitazone evaluated for cardiovascular outcomes--an interim analysis | Q34634794 | ||
| Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men. | Q34715022 | ||
| Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy | Q34829428 | ||
| Metabolic plasticity and the promotion of cardiac protection in ischemia and ischemic preconditioning | Q34977067 | ||
| High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets. | Q35012934 | ||
| Regulation of mitochondrial biogenesis by thyroid hormone | Q35054535 | ||
| Mitochondrial biogenesis as a cellular signaling framework. | Q35604970 | ||
| Resveratrol stimulates AMP kinase activity in neurons | Q35758555 | ||
| Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat | Q35762325 | ||
| The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression | Q35890670 | ||
| Nuclear receptor signaling and cardiac energetics | Q35890852 | ||
| The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome | Q35901803 | ||
| Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice | Q35970883 | ||
| A novel mouse model of lipotoxic cardiomyopathy | Q36016938 | ||
| The mitochondrial biogenesis regulatory program in cardiac adaptation to ischemia--a putative target for therapeutic intervention | Q36205354 | ||
| Nitric oxide and mitochondrial biogenesis: a key to long-term regulation of cellular metabolism | Q36223962 | ||
| Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer | Q36229684 | ||
| Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice | Q36330856 | ||
| Diabetic cardiomyopathy: the search for a unifying hypothesis | Q36423632 | ||
| Mitochondrial depolarization and the role of uncoupling proteins in ischemia tolerance | Q36567886 | ||
| Targeting the mitochondria to augment myocardial protection | Q36613672 | ||
| Diastolic dysfunction and diabetic cardiomyopathy: evaluation by Doppler echocardiography. | Q36625623 | ||
| PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle | Q36825520 | ||
| The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial | Q36825706 | ||
| Diabetic cardiomyopathy revisited | Q36860318 | ||
| Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells | Q36957828 | ||
| Functions and dysfunctions of mitochondrial dynamics | Q36967747 | ||
| Alterations in mitochondrial function and cytosolic calcium induced by hyperglycemia are restored by mitochondrial transcription factor A in cardiomyocytes | Q37016716 | ||
| Dramatic reversal of derangements in muscle metabolism and left ventricular function after bariatric surgery | Q37018348 | ||
| Muscular mitochondrial dysfunction and type 2 diabetes mellitus | Q37035872 | ||
| Heart failure with preserved ejection fraction: hypertension, diabetes, obesity/sleep apnea, and hypertrophic and infiltrative cardiomyopathy | Q37099735 | ||
| Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view | Q37179623 | ||
| Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy | Q37278004 | ||
| P433 | issue | 6 | |
| P921 | main subject | type 2 diabetes | Q3025883 |
| mitochondrion | Q39572 | ||
| P304 | page(s) | 842-849 | |
| P577 | publication date | 2009-02-13 | |
| P1433 | published in | Journal of Molecular and Cellular Cardiology | Q2061932 |
| P1476 | title | Type 2 diabetes, mitochondrial biology and the heart | |
| P478 | volume | 46 |
| Q39418943 | Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of a 3-Part Series |
| Q35028393 | Caloric excess or restriction mediated modulation of metabolic enzyme acetylation-proposed effects on cardiac growth and function |
| Q34334665 | Carbonylation of myosin heavy chains in rat heart during diabetes |
| Q33357265 | Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria |
| Q35767510 | Effects of N-acetylcysteine on nicotinamide dinucleotide phosphate oxidase activation and antioxidant status in heart, lung, liver and kidney in streptozotocin-induced diabetic rats |
| Q35601369 | Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart |
| Q35054122 | Estrogen and mitochondria function in cardiorenal metabolic syndrome |
| Q33892587 | Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside |
| Q51761073 | Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities. |
| Q38683468 | Ischemia reperfusion injury, ischemic conditioning and diabetes mellitus |
| Q39232678 | Ischemic postconditioning: mechanisms, comorbidities, and clinical application |
| Q37514855 | Long term liver specific glucokinase gene defect induced diabetic cardiomyopathy by up regulating NADPH oxidase and down regulating insulin receptor and p-AMPK. |
| Q35185255 | Longitudinal analysis of arterial blood pressure and heart rate response to acute behavioral stress in rats with type 1 diabetes mellitus and in age-matched controls |
| Q29871002 | MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism |
| Q41980324 | Mitochondria: from basic biology to cardiovascular disease |
| Q37158641 | Obesity and Cardiac Function - The Role of Caloric Excess and its Reversal |
| Q37731341 | Oxidative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase |
| Q38046547 | Oxidative stress and myocardial injury in the diabetic heart |
| Q35571792 | Phosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy |
| Q33616987 | Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats. |
| Q35003024 | Prolonged fasting identifies heat shock protein 10 as a Sirtuin 3 substrate: elucidating a new mechanism linking mitochondrial protein acetylation to fatty acid oxidation enzyme folding and function |
| Q42376949 | Rab4a signaling unmasks a pivotal link between myocardial homeostasis and metabolic remodeling in the diabetic heart |
| Q24313709 | SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress |
| Q26798052 | The Role of Cardiolipin in Cardiovascular Health |
| Q37398734 | The emerging characterization of lysine residue deacetylation on the modulation of mitochondrial function and cardiovascular biology |
| Q37961433 | The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging |
| Q36099360 | The role of comorbidities in cardioprotection |
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