scholarly article | Q13442814 |
P50 | author | E. Dale Abel | Q59100279 |
Bart C. Weimer | Q42290934 | ||
Brian T O'Neill | Q57755381 | ||
P2093 | author name string | Oleh Khalimonchuk | |
Sheldon E Litwin | |||
Dong Chen | |||
Sihem Boudina | |||
Kenneth J Rodnick | |||
Sandra Sena | |||
Xiaoming Sheng | |||
Heiko Bugger | |||
Jordan J Wright | |||
Olesya Ilkun | |||
Benjamin Wayment | |||
Vlad G Zaha | |||
Ryan Centini | |||
Timothy J Tidwell | |||
Eric Palfreyman | |||
Heather Theobald | |||
Pradip K Mazumder | |||
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Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat | Q72364841 | ||
Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload | Q73372293 | ||
Cardiac hypertrophy caused by peroxisome proliferator- activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling | Q81152659 | ||
Quantitative proteomic analysis by accurate mass retention time pairs | Q81598631 | ||
Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification | Q27887261 | ||
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Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat | Q28581995 | ||
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Cardiac remodeling in obesity. | Q34043589 | ||
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Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression | Q34789045 | ||
Glucose transport in the heart | Q35650780 | ||
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Diabetic cardiomyopathy revisited | Q36860318 | ||
Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. | Q36943690 | ||
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Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart | Q42455921 | ||
Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats | Q42477638 | ||
Overexpression of metallothionein reduces diabetic cardiomyopathy. | Q43833575 | ||
Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production | Q44328981 | ||
Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes | Q44480693 | ||
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Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice | Q46818652 | ||
Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy | Q46966545 | ||
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Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. | Q53541654 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mitochondrion | Q39572 |
oxidative stress | Q898814 | ||
preproinsulin | Q7240673 | ||
P304 | page(s) | 1272-1283 | |
P577 | publication date | 2009-02-23 | |
P1433 | published in | Circulation | Q578091 |
P1476 | title | Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart | |
P478 | volume | 119 |
Q94521883 | A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis |
Q54525101 | Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart. |
Q39361013 | Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart |
Q34424919 | Activation of mitochondrial energy metabolism protects against cardiac failure |
Q37212200 | Adrenergic receptors and metabolism: role in development of cardiovascular disease |
Q39897078 | Alterations in sarcoplasmic reticulum and mitochondrial functions in diabetic cardiomyopathy |
Q27931313 | Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. |
Q93048487 | Antioxidant and Adaptative Response Mediated by Nrf2 during Physical Exercise |
Q35931589 | Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome |
Q58803769 | Association of serum concentrations of irisin and the adipokines adiponectin and leptin with epicardial fat in cardiovascular surgery patients |
Q42709939 | Augmented oxidative stress and preserved vasoconstriction induced by hydrogen peroxide in coronary arteries in obesity: role of COX-2. |
Q36111734 | Autophagic adaptations in diabetic cardiomyopathy differ between type 1 and type 2 diabetes |
Q36929763 | Autophagy during cardiac stress: joys and frustrations of autophagy |
Q53690274 | CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy via PGC-1 α Activation. |
Q28236866 | Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy |
Q50290643 | Cardiac Development and Transcription Factors: Insulin Signalling, Insulin Resistance, and Intrauterine Nutritional Programming of Cardiovascular Disease |
Q92081950 | Cardiac Insulin Resistance in Heart Failure: The Role of Mitochondrial Dynamics |
Q90258679 | Cardiac adaptation to exercise training in health and disease |
Q37442678 | Cardiac aging and insulin resistance: could insulin/insulin-like growth factor (IGF) signaling be used as a therapeutic target? |
Q34570704 | Cardiac contractile function and mitochondrial respiration in diabetes-related mouse models |
Q27002459 | Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies |
Q36911630 | Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice |
Q34404106 | Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling. |
Q35731767 | Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice |
Q26751133 | Cardiovascular Action of Insulin in Health and Disease: Endothelial L-Arginine Transport and Cardiac Voltage-Dependent Potassium Channels |
Q92852811 | Contribution of Impaired Insulin Signaling to the Pathogenesis of Diabetic Cardiomyopathy |
Q33357265 | Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria |
Q36225147 | Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy |
Q28383474 | Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart |
Q34038623 | Diabetic cardiomyopathy, causes and effects |
Q51433129 | Dietary phytoestrogen supplementation induces sex differences in the myocardial protein pattern of mice: a comparative proteomics study. |
Q88773056 | EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter |
Q42800104 | EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice. |
Q35986147 | Early mitochondrial adaptations in skeletal muscle to diet-induced obesity are strain dependent and determine oxidative stress and energy expenditure but not insulin sensitivity |
Q57182869 | Effect of high-fat diet on rat myometrium during pregnancy-isolated myometrial mitochondria are not affected |
Q37746834 | Energetics and metabolism in the failing heart: important but poorly understood |
Q38069198 | Examining the role of insulin in the regulation of cardiovascular health. |
Q48634281 | Exercise Amaliorates Metabolic Disturbances and Oxidative Stress in Diabetic Cardiomyopathy: Possible Underlying Mechanisms. |
Q36632902 | Exercise Training Attenuates Upregulation of p47(phox) and p67(phox) in Hearts of Diabetic Rats |
Q98513881 | Exercise and cardiac health: physiological and molecular insights |
Q37586770 | Exercise mediated protection of diabetic heart through modulation of microRNA mediated molecular pathways |
Q37085587 | Extracorporeal membrane oxygenation promotes long chain fatty acid oxidation in the immature swine heart in vivo. |
Q52694977 | Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart. |
Q46265232 | Folic acid prevents cardiac dysfunction and reduces myocardial fibrosis in a mouse model of high-fat diet-induced obesity |
Q36814087 | Free fatty acid oxidation in insulin resistance and obesity |
Q35041039 | G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia. |
Q92172438 | GLUT4 expression and glucose transport in human induced pluripotent stem cell-derived cardiomyocytes |
Q35892530 | Genetic loss of insulin receptors worsens cardiac efficiency in diabetes. |
Q50958782 | Glucagon-like peptide-1 receptor activation reverses cardiac remodeling via normalizing cardiac steatosis and oxidative stress in type 2 diabetes. |
Q34369276 | HSPB2 is dispensable for the cardiac hypertrophic response but reduces mitochondrial energetics following pressure overload in mice |
Q36168834 | Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile Dysfunction in the Aging Myocardium |
Q33584533 | High-fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance |
Q90646232 | Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart |
Q36868348 | Human leukocyte/endothelial cell interactions and mitochondrial dysfunction in type 2 diabetic patients and their association with silent myocardial ischemia. |
Q37195069 | Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction |
Q89180789 | Increased Protein Tyrosine Phosphatase 1B (PTP1B) Activity and Cardiac Insulin Resistance Precede Mitochondrial and Contractile Dysfunction in Pressure-Overloaded Hearts |
Q34981029 | Increased systemic Th17 cytokines are associated with diastolic dysfunction in children and adolescents with diabetic ketoacidosis |
Q36976652 | Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury |
Q30377910 | Insulin Signaling and Heart Failure. |
Q46019226 | Insulin prevents aberrant mitochondrial phenotype in sensory neurons of type 1 diabetic rats. |
Q42818693 | Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. |
Q34056611 | Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training. |
Q38261284 | Insulin regulation of myocardial autophagy. |
Q38045550 | Insulin resistance and heart failure: molecular mechanisms |
Q36821424 | Insulin resistance: metabolic mechanisms and consequences in the heart. |
Q30945275 | Insulin signaling regulates mitochondrial function in pancreatic beta-cells |
Q37575998 | Is diabetic cardiomyopathy a specific entity? |
Q34162518 | Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice |
Q34502029 | Knockout of insulin receptors in cardiomyocytes attenuates coronary arterial dysfunction induced by pressure overload |
Q51280740 | Left ventricular vascular and metabolic adaptations to high-intensity interval and moderate intensity continuous training: a randomized trial in healthy middle-aged men. |
Q58781043 | Links Between Obesity-Induced Brain Insulin Resistance, Brain Mitochondrial Dysfunction, and Dementia |
Q37908843 | Lipotoxicity in type 2 diabetic cardiomyopathy |
Q63131766 | Mechanisms of physiological and pathological cardiac hypertrophy |
Q33635345 | Mir30c Is Involved in Diabetic Cardiomyopathy through Regulation of Cardiac Autophagy via BECN1 |
Q28391449 | Mitochondria and oxidative stress in heart aging |
Q24633336 | Mitochondria in the diabetic heart |
Q89878208 | Mitochondrial Mechanisms in Diabetic Cardiomyopathy |
Q46270660 | Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induces Post-Translational Modifications of AKAP121, DRP1 and OPA1 That Promote Mitochondrial Fission. |
Q35045900 | Mitochondrial adaptations to physiological vs. pathological cardiac hypertrophy |
Q28390863 | Mitochondrial dysfunction in diabetic cardiomyopathy |
Q35015797 | Mitochondrial dysfunction in patients with primary congenital insulin resistance |
Q39280722 | Mitochondrial miRNAs in diabetes: just the tip of the iceberg |
Q36049068 | Mitochondrial oxidative phosphorylation is impaired in patients with congenital lipodystrophy |
Q38198449 | Mitochondrial reactive oxygen species production and elimination |
Q53670749 | Mitofilin: Key factor in diabetic cardiomyopathy? |
Q64111781 | Molecular Mechanisms Responsible for Diastolic Dysfunction in Diabetes Mellitus Patients |
Q39280811 | Molecular Mechanisms Underlying Cardiac Adaptation to Exercise |
Q27006868 | Molecular basis of physiological heart growth: fundamental concepts and new players |
Q37672583 | Molecular mechanisms of diabetic cardiomyopathy. |
Q42477228 | Myocardial infarction in rats causes partial impairment in insulin response associated with reduced fatty acid oxidation and mitochondrial gene expression |
Q26752678 | New Molecular Insights of Insulin in Diabetic Cardiomyopathy |
Q35243945 | New insights into insulin resistance in the diabetic heart |
Q35543449 | Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance |
Q33958722 | Nonalcoholic fatty liver disease and the heart in children and adolescents |
Q59800367 | Of mice and men: models and mechanisms of diabetic cardiomyopathy |
Q38046547 | Oxidative stress and myocardial injury in the diabetic heart |
Q41016642 | Partial deletion of ROCK2 protects mice from high-fat diet-induced cardiac insulin resistance and contractile dysfunction |
Q37497833 | Pharmacological approaches to restore mitochondrial function |
Q38854987 | Physiological and pathological cardiac hypertrophy. |
Q37709197 | Protein kinase B (PKB/AKT1) formed signaling complexes with mitochondrial proteins and prevented glycolytic energy dysfunction in cultured cardiomyocytes during ischemia-reperfusion injury |
Q51615648 | Proteomics and metabolomics in biomarker discovery for cardiovascular diseases: progress and potential. |
Q42376949 | Rab4a signaling unmasks a pivotal link between myocardial homeostasis and metabolic remodeling in the diabetic heart |
Q51504003 | Role of the estrogen/estrogen-receptor-beta axis in the genomic response to pressure overload-induced hypertrophy. |
Q42853592 | Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axis |
Q40860092 | Sensitivity of Interfibrillar and Subsarcolemmal Mitochondria to Cobalt Chloride-induced Oxidative Stress and Hydrogen Sulfide Treatment. |
Q37734628 | Streptozotocin-induced diabetes prolongs twitch duration without affecting the energetics of isolated ventricular trabeculae. |
Q33676633 | Stress-triggered activation of the metalloprotease Oma1 involves its C-terminal region and is important for mitochondrial stress protection in yeast |
Q33566045 | Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart |
Q36415798 | Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner. |
Q55306046 | Sweet Mitochondria: A Shortcut to Alzheimer's Disease. |
Q37033248 | Telomeres and mitochondria in the aging heart |
Q38256368 | The "Goldilocks Zone" from a redox perspective-Adaptive vs. deleterious responses to oxidative stress in striated muscle |
Q37771129 | The SR-mitochondria interaction: a new player in cardiac pathophysiology. |
Q43084517 | The absence of cardiomyopathy is accompanied by increased activities of CAT, MnSOD and GST in long-term diabetes in rats |
Q37629260 | The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization |
Q37564467 | The afterload-dependent peak efficiency of the isolated working rat heart is unaffected by streptozotocin-induced diabetes. |
Q35803717 | The transcriptional coactivators, PGC-1α and β, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance |
Q38045769 | The unravelling of metabolic dysfunctions linked to metal-associated diseases by blue native polyacrylamide gel electrophoresis |
Q38034926 | Tissue-specific insulin signaling, metabolic syndrome, and cardiovascular disease |
Q37317428 | Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice. |
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Q36410680 | UCP3 regulates cardiac efficiency and mitochondrial coupling in high fat-fed mice but not in leptin-deficient mice. |
Q35667361 | Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathy |
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