| scholarly article | Q13442814 |
| P50 | author | E. Dale Abel | Q59100279 |
| P2093 | author name string | Christian Riehle | |
| P2860 | cites work | Growth hormone (GH)-induced insulin resistance is rapidly reversible: an experimental study in GH-deficient adults | Q84196702 |
| Impact of body mass index on mortality in heart failure patients | Q85832093 | ||
| Heart Disease and Stroke Statistics--2013 Update: A Report From the American Heart Association | Q22306356 | ||
| Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 | ||
| mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
| ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF | Q24304344 | ||
| Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart | Q24562618 | ||
| Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism | Q24603034 | ||
| Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study | Q24652963 | ||
| Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β-Cell Dysfunction | Q26800081 | ||
| Pathway-selective insulin resistance and metabolic disease: the importance of nutrient flux | Q26820876 | ||
| Insulin receptor signaling in normal and insulin-resistant states | Q26823171 | ||
| Cardiac energy metabolic alterations in pressure overload-induced left and right heart failure (2013 Grover Conference Series) | Q26825047 | ||
| Signaling effectors underlying pathologic growth and remodeling of the heart | Q26825154 | ||
| Adipokines - removing road blocks to obesity and diabetes therapy | Q26995825 | ||
| G protein-coupled receptor kinase 2: a link between myocardial contractile function and cardiac metabolism | Q27014769 | ||
| Modulation of glucose metabolism by the renin-angiotensin-aldosterone system | Q27026157 | ||
| Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth | Q27320013 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| TOR, a central controller of cell growth | Q27933354 | ||
| Obesity and the risk of heart failure | Q28216583 | ||
| Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes | Q28275582 | ||
| Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus | Q28297680 | ||
| The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress | Q28506886 | ||
| Role for Akt3/protein kinase Bgamma in attainment of normal brain size | Q28509294 | ||
| Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo | Q28511213 | ||
| Leptin signaling and obesity: cardiovascular consequences | Q36943073 | ||
| Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. | Q36943690 | ||
| Animal models of insulin resistance and heart failure | Q36944915 | ||
| Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy | Q36971848 | ||
| A short duration of high-fat diet induces insulin resistance and predisposes to adverse left ventricular remodeling after pressure overload | Q37038725 | ||
| Small G proteins in insulin action: Rab and Rho families at the crossroads of signal transduction and GLUT4 vesicle traffic | Q37048818 | ||
| Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome | Q37053844 | ||
| Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α | Q37054943 | ||
| Prolonged exposure to GH impairs insulin signaling in the heart. | Q37102358 | ||
| Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding | Q37176185 | ||
| Novel measurements of periaortic adipose tissue in comparison to anthropometric measures of obesity, and abdominal adipose tissue | Q37189942 | ||
| Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction | Q37195069 | ||
| Adipose tissue dysfunction in obesity, diabetes, and vascular diseases | Q37262617 | ||
| The role of epicardial and perivascular adipose tissue in the pathophysiology of cardiovascular disease | Q37293913 | ||
| Akt2 regulates cardiac metabolism and cardiomyocyte survival | Q37297743 | ||
| Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction. | Q37328748 | ||
| Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms. | Q37330288 | ||
| Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart. | Q37335886 | ||
| Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway | Q37403315 | ||
| Crosstalk between growth hormone and insulin signaling | Q37403955 | ||
| Induction of vascular insulin resistance and endothelin-1 expression and acceleration of atherosclerosis by the overexpression of protein kinase C-β isoform in the endothelium | Q37486289 | ||
| Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss | Q37491629 | ||
| Role of PI3K/AKT, cPLA2 and ERK1/2 signaling pathways in insulin regulation of vascular smooth muscle cells proliferation. | Q37522544 | ||
| Role of lipid-derived mediators in skeletal muscle insulin resistance. | Q37551374 | ||
| Molecular mechanisms of diabetic cardiomyopathy. | Q37672583 | ||
| Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease | Q37677929 | ||
| Mechanisms of obesity-induced hypertension. | Q37742440 | ||
| Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review | Q37813161 | ||
| Insulin signaling to hepatic lipid metabolism in health and disease. | Q37877710 | ||
| Selective insulin and leptin resistance in metabolic disorders | Q38033748 | ||
| FOXOs: signalling integrators for homeostasis maintenance | Q38074598 | ||
| Comparative safety and effectiveness of metformin in patients with diabetes mellitus and heart failure: systematic review of observational studies involving 34,000 patients. | Q38091002 | ||
| Heart failure-specific changes in protein kinase signalling. | Q38186583 | ||
| Insulin regulation of myocardial autophagy. | Q38261284 | ||
| Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns | Q38304071 | ||
| Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity | Q38319554 | ||
| Insulin resistance and impaired adipogenesis | Q38363838 | ||
| PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA. | Q54686097 | ||
| Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. | Q55067141 | ||
| PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects | Q57006372 | ||
| Myocardial Triglyceride Content and Epicardial Fat Mass in Human Obesity: Relationship to Left Ventricular Function and Serum Free Fatty Acid Levels | Q57623044 | ||
| Body composition and prognosis in chronic systolic heart failure: the obesity paradox | Q57652957 | ||
| The Obesity Paradox | Q59383543 | ||
| Survivin: A novel player in insulin cardioprotection against myocardial ischemia/reperfusion injury | Q64374834 | ||
| Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload | Q73372293 | ||
| Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study | Q73782355 | ||
| Elevated plasma fatty acid concentrations stimulate the cardiac autonomic nervous system in healthy subjects | Q74247579 | ||
| Elevated serum levels of leptin and soluble leptin receptor in patients with advanced chronic heart failure | Q78860332 | ||
| Immune activation is associated with reduced skeletal muscle mass and physical function in chronic heart failure | Q80384354 | ||
| The incidence of congestive heart failure in type 2 diabetes: an update | Q80384667 | ||
| Akt1 is required for physiological cardiac growth | Q83195147 | ||
| SnapShot: physiology of insulin signaling | Q83461706 | ||
| Hyperinsulinemia: effect on cardiac mass/function, angiotensin II receptor expression, and insulin signaling pathways | Q28565051 | ||
| PDK1 coordinates survival pathways and beta-adrenergic response in the heart | Q28585494 | ||
| Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells | Q28593272 | ||
| Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants | Q28771379 | ||
| Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta) | Q29615537 | ||
| Avoiding 40% of the premature deaths in each country, 2010-30: review of national mortality trends to help quantify the UN sustainable development goal for health | Q30062180 | ||
| Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association | Q30080021 | ||
| Prognostic impact of diabetes mellitus in patients with heart failure according to the etiology of left ventricular systolic dysfunction | Q33182324 | ||
| Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heart | Q33566045 | ||
| Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction | Q33568098 | ||
| Nutrient sensing and inflammation in metabolic diseases | Q33623354 | ||
| Lipotoxicity in the heart | Q33665107 | ||
| Risk factors for heart failure in the elderly: a prospective community-based study | Q33667197 | ||
| GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failure. | Q33680469 | ||
| Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats | Q33857313 | ||
| Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function. | Q33913178 | ||
| Insulin inhibits cardiac contractility by inducing a Gi-biased β2-adrenergic signaling in hearts. | Q33959744 | ||
| MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice | Q34028756 | ||
| Cardiac remodeling in obesity. | Q34043589 | ||
| Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training. | Q34056611 | ||
| Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy | Q34097448 | ||
| Lipotoxicity contributes to endothelial dysfunction: a focus on the contribution from ceramide. | Q34269858 | ||
| Akt/protein kinase B promotes organ growth in transgenic mice | Q34276940 | ||
| Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance | Q34380219 | ||
| Wasting as independent risk factor for mortality in chronic heart failure | Q34421966 | ||
| Myocardial insulin resistance induced by high fat feeding in heart failure is associated with preserved contractile function. | Q34426167 | ||
| Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways | Q34528355 | ||
| Ventricular assist device implantation improves skeletal muscle function, oxidative capacity, and growth hormone/insulin-like growth factor-1 axis signaling in patients with advanced heart failure | Q34590981 | ||
| Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis | Q34629081 | ||
| Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development. | Q34662451 | ||
| Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes | Q34673134 | ||
| Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression | Q34789045 | ||
| Glucose metabolism and cardiac hypertrophy | Q34808553 | ||
| Lipoapoptosis: its mechanism and its diseases | Q35047180 | ||
| Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes. | Q35069561 | ||
| Cardiac resynchronization therapy improves minute ventilation/carbon dioxide production slope and skeletal muscle capillary density without reversal of skeletal muscle pathology or inflammation | Q38457532 | ||
| Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy | Q38502148 | ||
| Impaired insulin action in the human brain: causes and metabolic consequences | Q38605675 | ||
| Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents | Q40238333 | ||
| Diabetes and cardiovascular disease. The Framingham study | Q41509493 | ||
| Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function | Q41817667 | ||
| Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity. | Q41969432 | ||
| Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure | Q42132463 | ||
| Phosphoinositide 3-kinase gamma-deficient mice are protected from isoproterenol-induced heart failure. | Q42447268 | ||
| Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density. | Q42485120 | ||
| Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial | Q42684584 | ||
| Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy | Q42750103 | ||
| Insulin receptor substrate signaling suppresses neonatal autophagy in the heart. | Q42818693 | ||
| PDK1 plays a critical role in regulating cardiac function in mice and human | Q42842800 | ||
| Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure | Q42928039 | ||
| Targeted GLUT-4 deficiency in the heart induces cardiomyocyte hypertrophy and impaired contractility linked with Ca(2+) and proton flux dysregulation | Q43229407 | ||
| Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice | Q43263000 | ||
| Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis | Q43645320 | ||
| Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice | Q43726502 | ||
| Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart | Q43954443 | ||
| Insulin resistance in moderate chronic heart failure is related to hyperleptinaemia, but not to norepinephrine or TNF-alpha | Q43963236 | ||
| Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy | Q44110224 | ||
| Rapamycin attenuates load-induced cardiac hypertrophy in mice | Q44385669 | ||
| Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy. | Q44686075 | ||
| Role of diabetes in congestive heart failure: the Framingham study | Q44758886 | ||
| Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women | Q44880994 | ||
| Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm | Q44912770 | ||
| Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload | Q44927100 | ||
| Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts. | Q45032380 | ||
| Uncoupling proteins in human heart | Q45149110 | ||
| Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy | Q45255903 | ||
| Autophagy maintains cardiac function in the starved adult. | Q45934984 | ||
| Coronary circulatory dysfunction in insulin resistance, impaired glucose tolerance, and type 2 diabetes mellitus. | Q46455337 | ||
| Functional and metabolic remodelling in GLUT4-deficient hearts confers hyper-responsiveness to substrate intervention | Q46811377 | ||
| Inhibition of glycogen synthase kinase 3beta during heart failure is protective | Q46977284 | ||
| The paradox of obesity in patients with heart failure | Q47299455 | ||
| Leptin receptor missense mutation in the fatty Zucker rat. | Q48064469 | ||
| Activation of Foxo1 by insulin resistance promotes cardiac dysfunction and β-myosin heavy chain gene expression. | Q48158054 | ||
| Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group. | Q50897068 | ||
| Acquired growth hormone resistance in patients with chronic heart failure: implications for therapy with growth hormone. | Q51547717 | ||
| Epicardial adipose tissue, hepatic steatosis and obesity. | Q51909922 | ||
| Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling. | Q52174749 | ||
| Insulin receptor substrate 3 is not essential for growth or glucose homeostasis. | Q52535322 | ||
| Mice lacking insulin receptor substrate 4 exhibit mild defects in growth, reproduction, and glucose homeostasis. | Q52537778 | ||
| Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. | Q53541654 | ||
| Reduction of insulin-like growth factor-I expression in the skeletal muscle of noncachectic patients with chronic heart failure. | Q53975324 | ||
| SnapShot: Insulin signaling pathways. | Q54532111 | ||
| S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt. | Q54561835 | ||
| Chronic Akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy. | Q54562272 | ||
| Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. | Q54609364 | ||
| Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity | Q35120903 | ||
| Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy | Q35126646 | ||
| PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy | Q35218804 | ||
| Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density | Q35543463 | ||
| Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy | Q35578778 | ||
| Glucose-lowering drugs or strategies and cardiovascular outcomes in patients with or at risk for type 2 diabetes: a meta-analysis of randomised controlled trials | Q35581749 | ||
| Glucose transport in the heart | Q35650780 | ||
| GLUT4 exocytosis. | Q35672106 | ||
| Cytosolic, but not mitochondrial, oxidative stress is a likely contributor to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice | Q35700338 | ||
| How free fatty acids inhibit glucose utilization in human skeletal muscle | Q35773111 | ||
| Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice | Q35780290 | ||
| Genetic loss of insulin receptors worsens cardiac efficiency in diabetes. | Q35892530 | ||
| Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome | Q35931589 | ||
| Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation | Q35965821 | ||
| The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. | Q35967120 | ||
| Ceramide mediates vascular dysfunction in diet-induced obesity by PP2A-mediated dephosphorylation of the eNOS-Akt complex | Q36047487 | ||
| Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2. | Q36100307 | ||
| A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy. | Q36156412 | ||
| Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo. | Q36186252 | ||
| Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia | Q36246003 | ||
| The conserved phosphoinositide 3-kinase pathway determines heart size in mice | Q36246110 | ||
| Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure | Q36298248 | ||
| Diaphragm dysfunction in heart failure is accompanied by increases in neutral sphingomyelinase activity and ceramide content | Q36306227 | ||
| Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy | Q36350066 | ||
| Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations | Q36399742 | ||
| Deletion of IGF-1 Receptors in Cardiomyocytes Attenuates Cardiac Aging in Male Mice | Q36431795 | ||
| Cardiovascular biology of the incretin system | Q36484283 | ||
| Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation. | Q36533391 | ||
| Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function | Q36646353 | ||
| Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes | Q36688361 | ||
| Insulin resistance: metabolic mechanisms and consequences in the heart. | Q36821424 | ||
| Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy | Q36824838 | ||
| Cardiovascular actions of insulin | Q36831533 | ||
| Diabetic cardiomyopathy revisited | Q36860318 | ||
| P433 | issue | 7 | |
| P921 | main subject | heart failure | Q181754 |
| preproinsulin | Q7240673 | ||
| P304 | page(s) | 1151-1169 | |
| P577 | publication date | 2016-04-01 | |
| P1433 | published in | Circulation Research | Q2599020 |
| P1476 | title | Insulin Signaling and Heart Failure | |
| P478 | volume | 118 |
| Q94521883 | A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis |
| Q91975494 | A risk prediction model for heart failure hospitalization in type 2 diabetes mellitus |
| Q51194041 | ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance. |
| Q48270121 | Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure. |
| Q64120834 | An adiponectin-S1P axis protects against lipid induced insulin resistance and cardiomyocyte cell death via reduction of oxidative stress |
| Q90722266 | Angiotensin II Influences Pre-mRNA Splicing Regulation by Enhancing RBM20 Transcription Through Activation of the MAPK/ELK1 Signaling Pathway |
| Q64105470 | Association between HOMA-IR and Frailty among U.S. Middle-aged and Elderly Population |
| Q53690274 | CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy via PGC-1 α Activation. |
| Q102053976 | Cardioprotective effects of short-term empagliflozin treatment in db/db mice |
| Q52560349 | Cardiovascular Metabolomics. |
| Q91669767 | Characterising an Alternative Murine Model of Diabetic Cardiomyopathy |
| Q90069130 | Chronic Pressure Overload Results in Deficiency of Mitochondrial Membrane Transporter ABCB7 Which Contributes to Iron Overload, Mitochondrial Dysfunction, Metabolic Shift and Worsens Cardiac Function |
| Q64066189 | Comparative outcomes of heart failure among existent classes of anti-diabetic agents: a network meta-analysis of 171,253 participants from 91 randomized controlled trials |
| Q39193265 | Cross-Talk Between Insulin Signaling and G Protein-Coupled Receptors |
| Q42315084 | Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum |
| Q59813541 | Direct Cardiac Actions of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure in Diabetic Patients |
| Q47098884 | Distinct impacts of sleep-disordered breathing on glycemic variability in patients with and without diabetes mellitus. |
| Q42800104 | EET intervention on Wnt1, NOV, and HO-1 signaling prevents obesity-induced cardiomyopathy in obese mice. |
| Q64936166 | Effects of Exercise to Improve Cardiovascular Health. |
| Q64076354 | Endothelial Insulin Resistance of Freshly Isolated Arterial Endothelial Cells From Radial Sheaths in Patients With Suspected Coronary Artery Disease |
| Q58795873 | Free fatty acid can induce cardiac dysfunction and alter insulin signaling pathways in the heart |
| Q64229774 | G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases |
| Q38665748 | Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart |
| Q64111852 | Glial Growth Factor 2 Regulates Glucose Transport in Healthy Cardiac Myocytes and During Myocardial Infarction via an Akt-Dependent Pathway |
| Q57255373 | Illuminating cell signaling with genetically encoded FRET biosensors in adult mouse cardiomyocytes |
| Q90730968 | Improvement of insulin signalling rescues inflammatory cardiac dysfunction |
| Q39232024 | Inflammation and metabolic cardiomyopathy |
| Q47649685 | Inhibition of galectin-3 ameliorates the consequences of cardiac lipotoxicity in a rat model of diet-induced obesity. |
| Q39159635 | Insulin and β Adrenergic Receptor Signaling: Crosstalk in Heart |
| Q90661468 | Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling |
| Q42257917 | Insulin supplementation attenuates cancer-induced cardiomyopathy and slows tumor disease progression |
| Q64284662 | Key inflammatory mechanisms underlying heart failure |
| Q92637716 | LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells |
| Q59138235 | Metabolic Effects of Metformin in the Failing Heart |
| Q41700538 | Metabolic Origins of Heart Failure. |
| Q55363508 | Metabolic and Cardiac Adaptation to Chronic Pharmacologic Blockade of Facilitative Glucose Transport in Murine Dilated Cardiomyopathy and Myocardial Ischemia. |
| Q93192737 | Metabolic remodeling induced by mitokines in heart failure |
| Q88779937 | Metabolic remodeling of substrate utilization during heart failure progression |
| Q93031892 | Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes |
| Q90842209 | Microvascular disease and heart failure with reduced and preserved ejection fraction in type 2 diabetes |
| Q53360179 | Multiphasic Regulation of Systemic and Peripheral Organ Metabolic Responses to Cardiac Hypertrophy. |
| Q60912597 | Nanotubular TiO regulates macrophage M2 polarization and increases macrophage secretion of VEGF to accelerate endothelialization via the ERK1/2 and PI3K/AKT pathways |
| Q90739975 | Novel Screening Method Identifies PI3Kα, mTOR, and IGF1R as Key Kinases Regulating Cardiomyocyte Survival |
| Q39198039 | Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels. |
| Q59800367 | Of mice and men: models and mechanisms of diabetic cardiomyopathy |
| Q39418956 | Oxidative Stress and Cardiovascular Risk: Obesity, Diabetes, Smoking, and Pollution: Part 3 of a 3-Part Series |
| Q51740466 | Pioglitazone Improved Insulin Sensitivity and First Phase Insulin Secretion Among Obese and Lean People with Diabetes: A Multicenter Clamp Study. |
| Q36353539 | Possible increase in insulin resistance and concealed glucose-coupled potassium-lowering mechanisms during acute coronary syndrome documented by covariance structure analysis |
| Q91805098 | Postprandial Insulin Response and Clearance Among Black and White Women: The Federal Women's Study |
| Q93030243 | Prescription patterns of diabetes medications influencing clinical outcomes of heart failure patients with reduced ejection fraction |
| Q57807757 | Revisiting the Diabetes-Heart Failure Connection |
| Q92956148 | Role and mechanism of cardiac insulin resistance in occurrence of heart failure caused by myocardial hypertrophy |
| Q38757077 | Role of melatonin in glucose uptake by cardiomyocytes from insulin-resistant Wistar rats. |
| Q38981243 | Role of microRNA in metabolic shift during heart failure |
| Q99631245 | Sex-Specific Programming of Cardiac DNA Methylation by Developmental Phthalate Exposure |
| Q93054062 | Small animal models of heart failure |
| Q90730113 | Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure |
| Q97067059 | The Histone Demethylase JMJD1C Regulates CAMKK2-AMPK Signaling to Participate in Cardiac Hypertrophy |
| Q102144602 | The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure |
| Q93147070 | Therapeutic Mechanisms of Herbal Medicines Against Insulin Resistance: A Review |
| Q90138898 | Upregulated hepatokine fetuin B aggravates myocardial ischemia/reperfusion injury through inhibiting insulin signaling in diabetic mice |
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