Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair

scientific article published on 28 May 2009

Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1091/MBC.E09-01-0085
P932PMC publication ID2710824
P698PubMed publication ID19477925

P50authorEva K. LeeQ75682803
P2093author name stringAli Pedram
Ellis R Levin
Mahnaz Razandi
Albert J Evinger
P2860cites workProximal events in signaling by plasma membrane estrogen receptorsQ38361235
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Membrane-associated binding sites for estrogen contribute to growth regulation of human breast cancer cellsQ43747232
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancerQ43864580
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p53 Induction: phosphorylation sites cooperate in regulatingQ44216801
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Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1.Q45967119
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Estradiol regulates tumor growth by influencing p53 and bcl-2 expression in human endometrial adenocarcinomas grown in nude miceQ71611608
Role of AKT1 in 17beta-estradiol- and insulin-like growth factor I (IGF-I)-dependent proliferation and prevention of apoptosis in MCF-7 breast carcinoma cellsQ78054808
Regulation of TopBP1 oligomerization by Akt/PKB for cell survivalQ24305051
Integration of the extranuclear and nuclear actions of estrogenQ24533536
Cloning of a novel receptor expressed in rat prostate and ovaryQ24607949
Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activationQ24670580
A transforming mutation in the pleckstrin homology domain of AKT1 in cancerQ27646556
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociationQ28206029
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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25Q28247761
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpointsQ28266170
Cell-cycle checkpoints and cancerQ28293996
Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI ratsQ28572162
Molecular origin of cancer: catechol estrogen-3,4-quinones as endogenous tumor initiatorsQ28645872
TopBP1 activates the ATR-ATRIP complexQ29614214
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesionsQ29614216
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisQ29614217
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 productionQ29614596
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGFQ29615227
Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.Q33925127
Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 functionQ33967106
Changes in regulatory phosphorylation of Cdc25C Ser287 and Wee1 Ser549 during normal cell cycle progression and checkpoint arrestsQ34148207
Knockout mouse models and mammary tumorigenesisQ34372852
Replication checkpoint enforced by kinases Cds1 and Chk1.Q34466698
Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer preventionQ34521885
Functional estrogen receptors in the mitochondria of breast cancer cellsQ34559531
ErbB receptors: new insights on mechanisms and biologyQ34579265
Site-specific phosphorylation of a checkpoint mediator protein controls its responses to different DNA structuresQ34649104
Antibodies to estrogen receptor: Immunochemical similarity of estrophilin from various mammalian speciesQ35048365
A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancerQ35052559
Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cellsQ35147106
Many fingers on the mitotic trigger: post-translational regulation of the Cdc25C phosphatase.Q35601099
Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasionQ35810732
Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and AktQ35918889
Pure oestrogen antagonists for the treatment of advanced breast cancerQ36586152
Steroid receptors and their role in the biology and control of breast cancer growthQ36673307
Estrogen receptors outside the nucleus in breast cancer.Q36860729
P433issue14
P921main subjectestrogenQ277954
P304page(s)3374-3389
P577publication date2009-05-28
P1433published inMolecular Biology of the CellQ2338259
P1476titleEstrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair
P478volume20

Reverse relations

cites work (P2860)
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