Cardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver.

scientific article published on 07 August 2013

Cardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/DMM.010470
P932PMC publication ID3820269
P698PubMed publication ID23929940

P50authorNadia RosenthalQ6957721
P2093author name stringPadmini Sarathchandra
Maria Paola Santini
Tommaso Poggioli
Jonas Lexow
P2860cites workCre recombinase resources for conditional mouse mutagenesis.Q53161346
Optimization of spatiotemporal gene inactivation in mouse heart by oral application of tamoxifen citrateQ60606964
Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and functionQ24657715
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stressQ28506886
A robust and high-throughput Cre reporting and characterization system for the whole mouse brainQ29616609
Tamoxifen-independent recombination in the RIP-CreER mouseQ33743071
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cellsQ33930407
Elimination of background recombination: somatic induction of Cre by combined transcriptional regulation and hormone binding affinity.Q34332650
Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injuryQ34657173
Systolic dysfunction in cardiac-specific ligand-inducible MerCreMer transgenic miceQ35087050
Cryptic loxP sites in mammalian genomes: genome-wide distribution and relevance for the efficiency of BAC/PAC recombineering techniques.Q35781787
Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction.Q36051055
Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death.Q37287468
Inducible site-directed recombination in mouse embryonic stem cellsQ39715564
Kinetics of tamoxifen-regulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeletonQ40300014
Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) miceQ42923082
A practical summary of site-specific recombination, conditional mutagenesis, and tamoxifen induction of CreERT2.Q42941347
Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytesQ43216744
Tamoxifen administration routes and dosage for inducible Cre-mediated gene disruption in mouse heartsQ43247329
Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre proteinQ43664631
Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 geneQ46071152
Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase.Q48505009
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P433issue6
P304page(s)1470-1476
P577publication date2013-08-07
P1433published inDisease Models & MechanismsQ1524006
P1476titleCardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver
P478volume6

Reverse relations

cites work (P2860)
Q27302178A Murine Myh6MerCreMer Knock-In Allele Specifically Mediates Temporal Genetic Deletion in Cardiomyocytes after Tamoxifen Induction
Q88698353Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload
Q35246035Activation of Cre recombinase alone can induce complete tumor regression
Q48435084Brain natriuretic peptide is able to stimulate cardiac progenitor cell proliferation and differentiation in murine hearts after birth.
Q36329482CAP2 in cardiac conduction, sudden cardiac death and eye development
Q35619146Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation
Q90918144Cardiac-specific knockout of Lmod2 results in a severe reduction in myofilament force production and rapid cardiac failure
Q39777742Chromosomal mapping of the αMHC-MerCreMer transgene in mice reveals a large genomic deletion
Q39157887Cre-loxP-Mediated Recombination: General Principles and Experimental Considerations
Q58577478Current Genetic Techniques in Neural Circuit Control of Feeding and Energy Metabolism
Q92225677Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging
Q92132803Dystrophin and calcium current are decreased in cardiomyocytes expressing Cre enzyme driven by αMHC but not TNT promoter
Q35779565Generation of a tamoxifen inducible Tnnt2MerCreMer knock-in mouse model for cardiac studies
Q28392538Genetic tools for identifying and manipulating fibroblasts in the mouse
Q30363420Gfi1Cre mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells.
Q42550103Giving credence to controls: Avoiding the false phenotype
Q52687182HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses.
Q64077215Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
Q92355881METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
Q39612063Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo
Q37287468Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death.
Q36770507New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism
Q35646064Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase
Q51308924PI3Kα is essential for the recovery from Cre/tamoxifen cardiotoxicity and in myocardial insulin signalling but is not required for normal myocardial contractility in the adult heart.
Q36021728Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic
Q30488138Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study
Q36875437STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart
Q64066322Targeting MRTF/SRF in CAP2-dependent dilated cardiomyopathy delays disease onset
Q42162747Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy.
Q92819797The Cre/lox system: Cre-ating unintended damage
Q42599011Using the mouse to model human disease: increasing validity and reproducibility
Q64051780iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications

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