scholarly article | Q13442814 |
P50 | author | Douglas Mashek | Q42873871 |
P2093 | author name string | Douglas G Mashek | |
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Dietary sugars stimulate fatty acid synthesis in adults | Q36898127 | ||
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Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease | Q37405640 | ||
Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity | Q37431796 | ||
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states | Q37445714 | ||
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition | Q37459831 | ||
Hepatic lipidosis in cats. | Q37518694 | ||
Role of hepatic desaturases in obesity-related metabolic disorders | Q37786185 | ||
Production, purification and characterization of adeno-associated vectors. | Q37807439 | ||
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis | Q37834857 | ||
The emerging roles of fatty acid translocase/CD36 and the aryl hydrocarbon receptor in fatty liver disease | Q37925317 | ||
The role of mitochondria in insulin resistance and type 2 diabetes mellitus | Q37930956 | ||
The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease | Q37963122 | ||
Increased risk of cardiovascular disease and chronic kidney disease in NAFLD. | Q38008136 | ||
Fatty acid-binding protein expression in the liver: its regulation and relationship to the zonation of fatty acid metabolism | Q38016357 | ||
Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease | Q38072666 | ||
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis | Q38090905 | ||
Sirtuins' modulation of autophagy | Q38108575 | ||
Regulation of autophagy by stress-responsive transcription factors | Q38111103 | ||
Gene expression in human NAFLD. | Q38292078 | ||
Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance | Q28583146 | ||
Impaired-inactivation of FoxO1 contributes to glucose-mediated increases in serum very low-density lipoprotein | Q28583188 | ||
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver | Q28583240 | ||
Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis | Q28585179 | ||
Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice | Q28589371 | ||
The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice | Q28593453 | ||
Mammalian mitochondrial glycerol-3-phosphate acyltransferase | Q28609581 | ||
Genetic basis of mitochondrial HMG-CoA synthase deficiency | Q28624003 | ||
Autophagy regulates lipid metabolism | Q29547421 | ||
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease | Q29614897 | ||
Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults | Q29614911 | ||
Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity | Q29614932 | ||
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease | Q29619334 | ||
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha | Q29620443 | ||
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase | Q30032295 | ||
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway | Q30425628 | ||
Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling | Q30425815 | ||
Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity | Q30433606 | ||
Altered lipid droplet dynamics in hepatocytes lacking triacylglycerol hydrolase expression | Q30494849 | ||
Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets. | Q30541918 | ||
Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation | Q33235063 | ||
Apolipoprotein B in the rough endoplasmic reticulum: translation, translocation and the initiation of lipoprotein assembly | Q33537983 | ||
Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism. | Q33613991 | ||
Role of acylCoA binding protein in acylCoA transport, metabolism and cell signaling | Q33637219 | ||
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis | Q33673834 | ||
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c | Q33785270 | ||
Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice | Q33852162 | ||
Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species | Q33901997 | ||
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP. | Q33953637 | ||
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis | Q34021724 | ||
Uptake of individual free fatty acids by skeletal muscle and liver in man | Q34074225 | ||
Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia | Q34094336 | ||
Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease | Q34101705 | ||
Liver fatty acid-binding protein and obesity | Q34120131 | ||
Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver | Q34125393 | ||
FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase | Q34149531 | ||
Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states | Q46921367 | ||
Overproduction of large VLDL particles is driven by increased liver fat content in man. | Q46931621 | ||
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression | Q46955933 | ||
Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. | Q47919939 | ||
ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver | Q50336015 | ||
Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study. | Q50665949 | ||
A role for seipin in lipid droplet dynamics and inheritance in yeast. | Q50669487 | ||
Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia. | Q51353898 | ||
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis. | Q51375339 | ||
Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation. | Q51379331 | ||
Ultrasonographic and biochemical evaluation of visceral obesity in obese women with non-alcoholic fatty liver disease. | Q51475558 | ||
Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease. | Q51495818 | ||
Temporal pattern of de novo lipogenesis in the postprandial state in healthy men. | Q51523783 | ||
Fasting hypoketotic coma in a child with deficiency of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase. | Q51573455 | ||
Factors affecting liver uptake of serum free stearic acid-1-C14. | Q51692999 | ||
Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass. | Q51838864 | ||
Evaluation of the affinity and turnover number of both hepatic mitochondrial and microsomal carnitine acyltransferases: relevance to intracellular partitioning of acyl-CoAs. | Q52083229 | ||
Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways. | Q53224130 | ||
Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning. | Q53485669 | ||
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. | Q53555710 | ||
Insulin regulation of triacylglycerol-rich lipoprotein synthesis and secretion. | Q54191086 | ||
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. | Q54495638 | ||
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver | Q57016669 | ||
Nonalcoholic Fatty Liver Disease in Severely Obese Subjects | Q58816508 | ||
Spillover of Dietary Fatty Acids and Use of Serum Nonesterified Fatty Acids for the Synthesis of VLDL-Triacylglycerol Under Two Different Feeding Regimens | Q59487259 | ||
Increased hepatic CD36 expression contributes to dyslipidemia associated with diet-induced obesity | Q64377000 | ||
The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion | Q66950215 | ||
Characteristics of oleate binding to liver plasma membranes and its uptake by isolated hepatocytes | Q67993662 | ||
Location and function of three sites phosphorylated on rat acetyl-CoA carboxylase by the AMP-activated protein kinase | Q68082700 | ||
Compartmentation of hepatic fatty-acid-binding protein in liver cells and its effect on microsomal phosphatidic acid biosynthesis | Q69499133 | ||
A Substrate- and Position-specific Acylation of sn-Glycerol 3-Phosphate by Rat Liver Mitochondria | Q70504237 | ||
Significance of Adipose Tissue and Liver as Sites of Fatty Acid Synthesis in the Pig and the Efficiency of Utilization of Various Substrates for Lipogenesis | Q71235790 | ||
Inhibition of liver microsomal carnitine acyltransferases by sulphonylurea drugs | Q72052203 | ||
Origin of triacylglycerol moiety of plasma very low density lipoproteins in the rat: structural studies | Q72133666 | ||
Lipogenesis in the pigeon: in vivo studies | Q72227352 | ||
Proteolysis and lipid-facilitated translocation are distinct but competitive processes that regulate secretion of apolipoprotein B in Hep G2 cells | Q72571322 | ||
Contribution of de novo fatty acid synthesis to very low density lipoprotein triacylglycerols: evidence from mass isotopomer distribution analysis of fatty acids synthesized from [2H6]ethanol | Q73053122 | ||
Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A | Q73064677 | ||
Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice | Q74061464 | ||
UPTAKE OF PLASMA FREE FATTY ACIDS BY THE ISOLATED RAT LIVER: EFFECT OF GLUCAGON | Q76554494 | ||
Use of cytosolic triacylglycerol hydrolysis products and of exogenous fatty acid for the synthesis of triacylglycerol secreted by cultured rat hepatocytes | Q77313684 | ||
Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking | Q80685047 | ||
Anthropometric and clinical factors associated with mortality in subjects with nonalcoholic fatty liver disease | Q85410881 | ||
Substrate inhibition of carnitine palmitoyltransferase by palmitoyl-CoA and activation by phospholipids and proteins | Q93629800 | ||
Comparative aspects of lipogenesis in mammalian tissues | Q93814281 | ||
Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways | Q34188050 | ||
CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance | Q34188075 | ||
Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? | Q34215212 | ||
Peroxisomal lipid degradation via beta- and alpha-oxidation in mammals | Q34236856 | ||
Splanchnic lipolysis in human obesity | Q34328357 | ||
Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents | Q34355263 | ||
Disordered lipid metabolism and the pathogenesis of insulin resistance | Q34370965 | ||
Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. | Q34451430 | ||
Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome | Q34503398 | ||
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning | Q34511046 | ||
Coactivation of Foxa2 through Pgc-1beta promotes liver fatty acid oxidation and triglyceride/VLDL secretion | Q34651716 | ||
Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy | Q34742779 | ||
Hepatic Hepatocyte Nuclear Factor 4α Is Essential for Maintaining Triglyceride and Cholesterol Homeostasis | Q34812700 | ||
Triglyceride accumulation protects against fatty acid-induced lipotoxicity | Q34866329 | ||
Biochemical and physiological function of stearoyl-CoA desaturase | Q34898764 | ||
Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. | Q34935273 | ||
Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids | Q34989773 | ||
Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance. | Q35186665 | ||
Obesity, insulin resistance and free fatty acids | Q35204838 | ||
Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling | Q35235426 | ||
New concepts of cellular fatty acid uptake: role of fatty acid transport proteins and of caveolae. | Q35855938 | ||
Invited review: pathology, etiology, prevention, and treatment of fatty liver in dairy cows | Q35891776 | ||
Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. | Q35897072 | ||
Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. | Q35913725 | ||
Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene | Q35922205 | ||
Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver | Q35958436 | ||
The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 | Q35958448 | ||
FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c | Q36016844 | ||
Opposing roles of cell death-inducing DFF45-like effector B and perilipin 2 in controlling hepatic VLDL lipidation | Q36145221 | ||
Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly | Q36339529 | ||
Nonalcoholic fatty liver disease (NAFLD): is it really a serious condition? | Q36438823 | ||
Cellular fatty acid uptake: the contribution of metabolism | Q36470872 | ||
Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice | Q36479005 | ||
Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis. | Q38309701 | ||
Reciprocal regulation of hepatic and adipose lipogenesis by liver X receptors in obesity and insulin resistance | Q38314419 | ||
Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice | Q38323956 | ||
PPARgamma2 regulates lipogenesis and lipid accumulation in steatotic hepatocytes. | Q38332175 | ||
Influence of Dietary Lipid on Lipogenic Enzyme Activities in Coho Salmon, Oncorhynchus kisutch (Walbaum) | Q39145371 | ||
Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism | Q39193322 | ||
Diacylglycerol acyltransferase 2 acts upstream of diacylglycerol acyltransferase 1 and utilizes nascent diglycerides and de novo synthesized fatty acids in HepG2 cells | Q39322543 | ||
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. | Q39616865 | ||
Caloric Homeostasis and Disorders of Fuel Transport | Q39919368 | ||
Gluconeogenesis and lipogenesis in tissue from ruminant and nonruminant animals | Q39977411 | ||
Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice | Q40041201 | ||
Membrane binding proteins are the major determinants for the hepatocellular transmembrane flux of long-chain fatty acids bound to albumin | Q40386781 | ||
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. | Q40477651 | ||
Triacylglycerol hydrolase is localized to the endoplasmic reticulum by an unusual retrieval sequence where it participates in VLDL assembly without utilizing VLDL lipids as substrates. | Q40480335 | ||
A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis | Q40691066 | ||
The late addition of core lipids to nascent apolipoprotein B100, resulting in the assembly and secretion of triglyceride-rich lipoproteins, is independent of both microsomal triglyceride transfer protein activity and new triglyceride synthesis | Q40769306 | ||
Lipoprotein metabolism and fattening in poultry | Q41481264 | ||
Intracellular degradation of newly synthesized apolipoprotein B. | Q41646693 | ||
Autophagy-lysosomal pathway is involved in lipid degradation in rat liver. | Q41929863 | ||
FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes | Q42131271 | ||
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. | Q42462295 | ||
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. | Q42468549 | ||
Liver specific inactivation of carboxylesterase 3/triacylglycerol hydrolase decreases blood lipids without causing severe steatosis in mice | Q42508123 | ||
Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter | Q42835179 | ||
Fatty acid metabolism in the liver, measured by positron emission tomography, is increased in obese individuals | Q42946610 | ||
Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes | Q42982648 | ||
Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities | Q43552270 | ||
The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways | Q43564087 | ||
Fatty acid biosynthesis in liver and adipose tissue from dogs | Q43987761 | ||
A species comparison of liver slice synthesis and secretion of triacylglycerol from nonesterified fatty acids in media | Q44089541 | ||
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome | Q44385945 | ||
Long-term follow-up of patients with nonalcoholic fatty liver | Q44431564 | ||
Short communication: Net uptake of nonesterified long chain fatty acids by the perfused caudate lobe of the caprine liver | Q44437158 | ||
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. | Q44477314 | ||
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease | Q44664390 | ||
Liver fatty acid binding protein is required for high rates of hepatic fatty acid oxidation but not for the action of PPARalpha in fasting mice | Q44680979 | ||
Increase in long-chain polyunsaturated fatty acid n - 6/n - 3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease | Q44726439 | ||
Real-time assessment of postprandial fat storage in liver and skeletal muscle in health and type 2 diabetes | Q45168907 | ||
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms | Q45300618 | ||
LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. | Q45982093 | ||
Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets | Q46121875 | ||
Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease | Q46215726 | ||
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. | Q46442905 | ||
Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans | Q46579067 | ||
Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis | Q46660978 | ||
Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus | Q46667867 | ||
Relationship of hepatic steatosis to adipose tissue distribution in pediatric nonalcoholic fatty liver disease | Q46872820 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | fatty acid | Q61476 |
P304 | page(s) | 697-710 | |
P577 | publication date | 2013-11-06 | |
P1433 | published in | Advances in Nutrition | Q20821073 |
P1476 | title | Hepatic fatty acid trafficking: multiple forks in the road | |
P478 | volume | 4 |
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Q55443852 | Direct effects of thyroid hormones on hepatic lipid metabolism. |
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Q47642289 | High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine. |
Q41991541 | Host-derived fatty acids activate type VII secretion in Staphylococcus aureus |
Q38839502 | Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids |
Q39253589 | Lipid droplets and liver disease: from basic biology to clinical implications. |
Q59340375 | Liver-specific Repin1 deficiency impairs transient hepatic steatosis in liver regeneration |
Q96953670 | Long Non-coding RNA and mRNA Profile of Liver Tissue During Four Developmental Stages in the Chicken |
Q38672086 | Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance |
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