scholarly article | Q13442814 |
P50 | author | Antonino Belfiore | Q57028878 |
P2093 | author name string | Haim Werner | |
Rive Sarfstein | |||
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pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167 | Q24533505 | ||
Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene | Q28118453 | ||
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Insulin-like growth factor-i regulates Kruppel-like factor-6 gene expression in a p53-dependent manner. | Q52584374 | ||
Circulating concentrations of insulin-like growth factor I and risk of breast cancer | Q57751183 | ||
Enhancement of Insulin-Like Growth Factor Signaling in Human Breast Cancer: Estrogen Regulation of Insulin Receptor Substrate-1 Expressionin Vitroandin Vivo | Q62267728 | ||
Regulation of Insulin-Like Growth Factor-Binding Protein (IGFBP) Expression by Breast Cancer Cells: Use of IGFBP-1 as as Inhibitor of Insulin-like Growth Factor Action | Q62267755 | ||
Analysis of the human type I insulin-like growth factor receptor promoter region | Q67693079 | ||
Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer | Q69656778 | ||
Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer | Q72526379 | ||
Down-regulation of insulin-like growth factor-I receptor and insulin receptor substrate-1 expression in advanced human breast cancer | Q73259722 | ||
A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I | Q73274526 | ||
The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue | Q74295881 | ||
The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma | Q80282025 | ||
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase | Q29617567 | ||
Improving large-scale proteomics by clustering of mass spectrometry data. | Q30917029 | ||
Function of the IGF-I receptor in breast cancer | Q33904112 | ||
FAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cells | Q33986318 | ||
Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein: potential interactions between KLF6 and p53. | Q34319231 | ||
Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice | Q34578428 | ||
Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway. | Q34632213 | ||
The IGFI receptor gene: a molecular target for disrupted transcription factors | Q35036870 | ||
Type 1 IGF receptor in human breast diseases | Q35465137 | ||
Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product | Q36378010 | ||
Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts | Q36653985 | ||
Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor | Q36696132 | ||
Implications of applied research for prognosis and therapy of breast cancer | Q37074906 | ||
Affinity purification of sequence-specific DNA binding proteins | Q37394403 | ||
Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site | Q38308828 | ||
Structural and functional analysis of the insulin-like growth factor I receptor gene promoter | Q38325320 | ||
Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations | Q40086113 | ||
A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo | Q40099249 | ||
Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1. | Q40196099 | ||
The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells | Q40369437 | ||
The WT1 Wilms' tumor suppressor gene product interacts with estrogen receptor-alpha and regulates IGF-I receptor gene transcription in breast cancer cells | Q40387187 | ||
The insulin-like growth factor system as a target in breast cancer | Q40396511 | ||
In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors | Q40433669 | ||
Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1. | Q40519472 | ||
WT1-p53 interactions in insulin-like growth factor-I receptor gene regulation | Q40688483 | ||
Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth | Q40789384 | ||
The role of the insulin-like growth factor system in human cancer | Q41035980 | ||
The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein | Q41175804 | ||
Estradiol Down-Regulates the Mannose-6-Phosphate/Insulin-Like Growth Factor-II Receptor Gene and Induces Cathepsin-D in Breast Cancer Cells: A Receptor Saturation Mechanism to Increase the Secretion of Lysosomal Proenzymes | Q41682889 | ||
Role of estrogen-induced insulin-like growth factors in the proliferation of human breast cancer cells | Q41710584 | ||
Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells | Q41711044 | ||
Type I insulin-like growth factor receptor function in breast cancer. | Q41727242 | ||
IGF system components as prognostic markers in breast cancer. | Q41727250 | ||
Insulin-like growth factor receptor expression and function in human breast cancer | Q41753631 | ||
Insulin receptor substrate 1 is a target for the pure antiestrogen ICI 182,780 in breast cancer cells | Q42470095 | ||
Regulation of insulin-like growth factor I receptor gene expression by Sp1: physical and functional interactions of Sp1 at GC boxes and at a CT element | Q42474843 | ||
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation | Q42798205 | ||
ATM is a target for positive regulation by E2F-1. | Q42806424 | ||
An intact and functional soluble form of the insulin receptor is secreted by cultured cells. | Q42806584 | ||
Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway | Q43516376 | ||
BRCA1–Sp1 interactions in transcriptional regulation of the IGF‐IR gene | Q44411062 | ||
Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor | Q44490891 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | estrogen | Q277954 |
preproinsulin | Q7240673 | ||
P304 | page(s) | 233-261 | |
P577 | publication date | 2010-03-25 | |
P1433 | published in | Cancers | Q27722963 |
P1476 | title | Identification of Insulin-Like Growth Factor-I Receptor (IGF-IR) Gene Promoter-Binding Proteins in Estrogen Receptor (ER)-Positive and ER-Depleted Breast Cancer Cells | |
P478 | volume | 2 |
Q38641329 | Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies |
Q26742114 | Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways |
Q36074111 | Insulin-like growth factor-1 signaling in renal cell carcinoma |
Q35710097 | Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells |
Q28486318 | Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners |
Q92296751 | Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors |
Q39043458 | Prognostic value of cross-omics screening for kidney clear cell renal cancer survival |
Q35535296 | Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation |
Q42409060 | TMPRSS2-ERG fusion protein regulates insulin-like growth factor-1 receptor (IGF1R) gene expression in prostate cancer: involvement of transcription factor Sp1. |
Q93104633 | The Influence of Curcumin on the Downregulation of MYC, Insulin and IGF-1 Receptors: A possible Mechanism Underlying the Anti-Growth and Anti-Migration in Chemoresistant Colorectal Cancer Cells |
Q37551261 | The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells |
Q35105295 | The role of the insulin-like growth factor-1 system in breast cancer |
Q97421864 | Tumor suppressor p53 regulates insulin receptor (INSR) gene expression via direct binding to the INSR promoter |
Q37941372 | Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer |
Q46894191 | Werner et al. Identification of Insulin-Like Growth Factor-I Receptor (IGF-IR) Gene Promoter-Binding Proteins in Estrogen Receptor (ER)-Positive and ER-Depleted Breast Cancer Cells |
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