Diabetes and atherosclerosis: is there a role for hyperglycemia?

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Diabetes and atherosclerosis: is there a role for hyperglycemia? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1194/JLR.R800059-JLR200
P932PMC publication ID2674740
P698PubMed publication ID19029122

P50authorKarin E. BornfeldtQ87887672
P2093author name stringAlan Chait
P2860cites workIntensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 DiabetesQ22250887
Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic miceQ24530027
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) GroupQ27860882
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetesQ29547541
Effects of intensive glucose lowering in type 2 diabetesQ29547736
The pathobiology of diabetic complications: a unifying mechanismQ29617766
Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: United Kingdom Prospective Diabetes Study (UKPDS: 23)Q33764951
Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathwayQ34229420
Efficacy of lipid lowering drug treatment for diabetic and non-diabetic patients: meta-analysis of randomised controlled trialsQ34601330
Scavenger receptors that recognize advanced glycation end productsQ34871996
Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: a new crossroad of AGE to cholesterol metabolismQ35079451
The metabolic syndrome: more than the sum of its parts?Q35546619
The effect of alloxan diabetes on experimental cholesterol atherosclerosis in the rabbit. III. The mechanism of the inhibition of experimental cholesterol atherosclerosis in alloxan-diabetic rabbitsQ36261543
Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?Q36775094
Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.Q36883079
Changes in glycaemic control and risk of coronary artery disease in type 1 diabetes mellitus: findings from the Pittsburgh Epidemiology of Diabetes Complications Study (EDC).Q36928042
Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studiesQ37172727
High glucose induces IL-1beta expression in human monocytes: mechanistic insightsQ37176774
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins.Q38309468
Atherosclerosis and insulin in primates with diabetes mellitusQ39835559
Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alphaQ40701120
Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproductsQ41009444
Upregulation of glucose metabolism during intimal lesion formation is coupled to the inhibition of vascular smooth muscle cell apoptosis. Role of GSK3betaQ43596041
Elevated ambient glucose induces acute inflammatory events in the microvasculature: effects of insulinQ43606088
Diabetes-induced accelerated atherosclerosis in swineQ43651836
Human arterial smooth muscle cells rapidly deplete cell culture media of glucoseQ43694766
Increased atherosclerosis in diabetic dyslipidemic swine: protection by atorvastatin involves decreased VLDL triglycerides but minimal effects on the lipoprotein profileQ44168286
NCEP-Defined Metabolic Syndrome, Diabetes, and Prevalence of Coronary Heart Disease Among NHANES III Participants Age 50 Years and OlderQ44418730
Diabetes and Glucose Tolerance as Risk Factors for Cardiovascular Disease: The Framingham StudyQ44680472
Effect of streptozotocin-induced hyperglycemia on lipid profiles, formation of advanced glycation endproducts in lesions, and extent of atherosclerosis in LDL receptor-deficient miceQ45120387
The Pittsburgh insulin-dependent diabetes mellitus (IDDM) morbidity and mortality study. Mortality results.Q50587712
Long-term follow-up after tight control of blood pressure in type 2 diabetes.Q51122414
Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?Q51615482
Effect of intensive diabetes management on macrovascular events and risk factors in the Diabetes Control and Complications TrialQ72198055
Short-term high glucose exposure induces monocyte-endothelial cells adhesion and transmigration by increasing VCAM-1 and MCP-1 expression in human aortic endothelial cellsQ79348211
P921main subjectatherosclerosisQ12252367
hyperglycemiaQ271993
P304page(s)S335-9
P577publication date2008-11-23
P1433published inJournal of Lipid ResearchQ6295449
P1476titleDiabetes and atherosclerosis: is there a role for hyperglycemia?
P478volume50 Suppl

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cites work (P2860)
Q361536901H-NMR-based metabolomic analysis of cerebrospinal fluid from adult bilateral moyamoya disease: comparison with unilateral moyamoya disease and atherosclerotic stenosis
Q35415550Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process.
Q35852679Amelioration of Hyperglycemia with a Sodium-Glucose Cotransporter 2 Inhibitor Prevents Macrophage-Driven Atherosclerosis through Macrophage Foam Cell Formation Suppression in Type 1 and Type 2 Diabetic Mice
Q35903298Animal models of atherosclerosis
Q46568863Antihyperglycemia and Antihyperlipidemia Effect of Protoberberine Alkaloids From Rhizoma Coptidis in HepG2 Cell and Diabetic KK-Ay Mice
Q38785900Antioxidant effects of curcuminoids in patients with type 2 diabetes mellitus: a randomized controlled trial
Q38005031Cardiovascular disease risk in young people with type 1 diabetes.
Q37845224Cardiovascular function/dysfunction in adolescents with type 1 diabetes.
Q34523776Comparison of carotid and lower limb atherosclerotic lesions in both previously known and newly diagnosed type 2 diabetes mellitus
Q36658372Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation
Q34399952Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice
Q89030137Endothelial Glycocalyx as a Shield Against Diabetic Vascular Complications: Involvement of Hyaluronan and Hyaluronidases
Q36760787Endovascular versus medical therapy for atherosclerotic renovascular disease
Q36942187Fasting glucose level and the risk of incident atherosclerotic cardiovascular diseases.
Q34501763Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors
Q60044940GLP-1RAs in type 2 diabetes: mechanisms that underlie cardiovascular effects and overview of cardiovascular outcome data
Q37338605Genotypic and phenotypic heterogeneity in Streptococcus mutans isolated from diabetic patients in Rome, Italy
Q91559781Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
Q30845405Glucose regulation, cognition, and brain MRI in type 2 diabetes: a systematic review
Q27024469Glycemic control and cardiovascular disease: what's a doctor to do?
Q58122681Increased Expression of Resistin in MicroRNA-155-Deficient White Adipose Tissues May Be a Possible Driver of Metabolically Healthy Obesity Transition to Classical Obesity
Q91795685Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes
Q36955142Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway
Q99578648Inhibition of Notch Signaling Alleviated Diabetic Macrovasculopathy in an In Vitro Model
Q35603190Intermittent high glucose implements stress-induced senescence in human vascular endothelial cells: role of superoxide production by NADPH oxidase
Q45398280Isolated post-challenge hyperglycaemia and risk of cardiovascular events: Tehran Lipid and Glucose Study
Q35750322LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2.
Q37432907Long-term effects intensive medical therapy on the development and progression of subclinical atherosclerosis and the metabolic syndrome in Chinese patients with type 2 diabetes mellitus.
Q40050071Longitudinal Change in Fasting Blood Glucose and Myocardial Infarction Risk in a Population Without Diabetes
Q38834990Medical Therapy in Peripheral Artery Disease and Critical Limb Ischemia
Q92664771Metabolic influence on macrophage polarization and pathogenesis
Q93011588Metformin Attenuates Early-Stage Atherosclerosis in Mildly Hyperglycemic Oikawa-Nagao Mice
Q26782445Molecular Pathways Regulating Macrovascular Pathology and Vascular Smooth Muscle Cells Phenotype in Type 2 Diabetes
Q89967822Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes
Q90416246Nonalcoholic Fatty Liver Disease
Q42835376Pharmacological effects of the water fraction of key components in the traditional Chinese prescription Mai Tong Fang on 3T3-L1 adipocytes and ob/ob diabetic mice
Q38628797Potential therapeutic effects of mTOR inhibition in atherosclerosis.
Q40684687Relation between anti-atherosclerotic effects of IRAK4 and modulation of vascular smooth muscle cell phenotype in diabetic rats
Q35757573Repetitive Glucose Spikes Accelerate Atherosclerotic Lesion Formation in C57BL/6 Mice.
Q46305214Resveratrol attenuates high glucose-induced endothelial cell apoptosis via mediation of store-operated calcium entry
Q38181177Retinoid X receptor ligands: a patent review (2007 - 2013).
Q46267252Role of protein carbonylation in diabetes
Q44926429Stimulation of phagocyte adhesion to endothelial cells by modified VLDL and HDL requires scavenger receptor BI.
Q33872769The Predictive Role of Tooth Extractions, Oral Infections, and hs-C-Reactive Protein for Mortality in Individuals with and without Diabetes: A Prospective Cohort Study of a 12 1/2-Year Follow-Up
Q55416114The Role of Advanced Glycation End Products in Diabetic Vascular Complications.
Q35119269The flavonols quercetin and 3',4'-dihydroxyflavonol reduce platelet function and delay thrombus formation in a model of type 1 diabetes
Q37106132The relationship between HbA₁c and ultrasound plaque textures in atherosclerotic patients
Q37954396Toll-like receptors and diabetes: a therapeutic perspective
Q54968435Vitamin D3 Induces Gene Expression of Ox-LDL Scavenger Receptors in Streptozotocin-Induced Diabetic Rat Aortas: New Insight into the Role of Vitamin D in Diabetic Atherosclerosis.

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