Karin E. Bornfeldt

researcher 0000-0001-9208-6523

Karin E. Bornfeldt is …
instance of (P31):
humanQ5

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P496ORCID iD0000-0001-9208-6523

P1416affiliationUniversity of Washington Department of Laboratory Medicine and PathologyQ99264783
P166award receivedFellow of the American Heart AssociationQ105670306
Special Recognition Award in Vascular BiologyQ124980531
P185doctoral studentValerie Z. WallQ118213492
P108employerUniversity of WashingtonQ219563
P735given nameKarinQ1814118
KarinQ1814118
P106occupationresearcherQ1650915
P5008on focus list of Wikimedia projectWikiProject PCC Wikidata Pilot/University of WashingtonQ98970039
P21sex or genderfemaleQ6581072

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author (P50)
Q376666712013 Russell Ross memorial lecture in vascular biology: cellular and molecular mechanisms of diabetes mellitus-accelerated atherosclerosis
Q50904472A Long Road Ahead for Discovering New HDL Metrics That Reflect Cardiovascular Disease Risk.
Q99593566A New Treatment Strategy for Diabetic Dyslipidemia?
Q52684469A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.
Q46350486A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis
Q89606407A Role of the Heme Degradation Pathway in Shaping Prostate Inflammatory Responses and Lipid Metabolism
Q79234273A single second messenger: several possible cellular responses depending on distinct subcellular pools
Q36742281Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages
Q39454322Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages
Q33724394Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity
Q35088381Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficien
Q92045246Albuminuria, the High-Density Lipoprotein Proteome, and Coronary Artery Calcification in Type 1 Diabetes Mellitus
Q33332589An inducible and reversible mouse genetic rescue system
Q90439211Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques
Q91116797Apolipoprotein A1 Forms 5/5 and 5/4 Antiparallel Dimers in Human High-density Lipoprotein
Q104134617Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes
Q34342384Arterial smooth muscle
Q103799098Association of apolipoprotein C3 with insulin resistance and coronary artery calcium in patients with type 1 diabetes
Q36602802Atherosclerosis: Successes, Surprises, and Future Challenges
Q55265082Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.
Q112736789Conformational flexibility of apolipoprotein A-I amino- and carboxy-termini is necessary for lipid binding but not cholesterol efflux
Q27334219Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships
Q91717118Correction: Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity
Q43850804Cyclic AMP-specific phosphodiesterase 4 inhibitors promote ABCA1 expression and cholesterol efflux
Q35204728Cyclic GMP phosphodiesterases and regulation of smooth muscle function
Q34113265Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation
Q38349580Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.
Q98579723Diabetes Impairs Cellular Cholesterol Efflux from ABCA1 to Small HDL Particles
Q37333371Diabetes and atherosclerosis: is there a role for hyperglycemia?
Q37486465Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions
Q35849515Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Q33901965Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys
Q42964142Diabetes-accelerated atherosclerosis and inflammation
Q36199128Diabetic vascular disease and the potential role of macrophage glucose metabolism
Q35672692Direct effects of long-chain non-esterified fatty acids on vascular cells and their relevance to macrovascular complications of diabetes
Q36775094Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques?
Q37083092Does Elevated Glucose Promote Atherosclerosis? Pros and Cons
Q35653968Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice
Q95317816Emerging Targets for Cardiovascular Disease Prevention in Diabetes
Q36558881Endothelial acyl-CoA synthetase 1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment
Q42867693Evidence stacks up that endothelial insulin resistance is a culprit in atherosclerosis.
Q43152176GPIHBP1: two get tangled
Q30277854Genetic association of long-chain acyl-CoA synthetase 1 variants with fasting glucose, diabetes, and subclinical atherosclerosis
Q35860833Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion
Q91584914Growing evidence for a role for acyl-CoA synthetase 1 in immunometabolism
Q93034636Hematopoietic Cell-Expressed Endothelial Nitric Oxide Protects the Liver From Insulin Resistance
Q90615969High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes
Q49789890High-Density Lipoprotein Function in Cardiovascular Disease and Diabetes Mellitus.
Q90757084Highlighting Residual Atherosclerotic Cardiovascular Disease Risk
Q93177836How Far We Have Come, How Far We Have Yet to Go in Atherosclerosis Research
Q35212858How does diabetes accelerate atherosclerotic plaque rupture and arterial occlusion?
Q45161321Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL.
Q98735051Hypertriglyceridemia and Atherosclerosis: Using Human Research to Guide Mechanistic Studies in Animal Models
Q81164457IGF-I/insulin hybrid receptors in human endothelial cells
Q37149768Impact of Diabetes Mellitus
Q91795685Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes
Q38059912Inflammation and diabetes-accelerated atherosclerosis: myeloid cell mediators.
Q46381890Inflammatory stimuli induce acyl-CoA thioesterase 7 and remodeling of phospholipids containing unsaturated long (≥C20)-acyl chains in macrophages.
Q42854565Integrin alpha(7)beta(1) COMPels smooth muscle cells to maintain their quiescence
Q93177849Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis
Q26860086Lipids and the endothelium: bidirectional interactions
Q35140825Lipids versus glucose in inflammation and the pathogenesis of macrovascular disease in diabetes
Q50061471Liver Kinase B1 Links Macrophage Metabolism Sensing and Atherosclerosis
Q24337408Long-chain acyl-CoA synthetase 4 modulates prostaglandin E₂ release from human arterial smooth muscle cells
Q55001106Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics.
Q36602809Macrophage Phenotype and Function in Different Stages of Atherosclerosis
Q34068374Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase
Q26796679Metabolic Flexibility and Dysfunction in Cardiovascular Cells
Q36371123Microvascular management of systemic insulin sensitivity
Q27332357Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice
Q89967822Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes
Q36766171Mouse models for studies of cardiovascular complications of type 1 diabetes
Q36063184Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes
Q89068457Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation
Q50102325Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor
Q38033682Novel insights into the role of S100A8/A9 in skin biology
Q83018858Nuclear signaling in smooth muscle cells: cyclic nucleotide phosphodiesterase 1A moves in
Q44077331Oleate and linoleate enhance the growth-promoting effects of insulin-like growth factor-I through a phospholipase D-dependent pathway in arterial smooth muscle cells
Q33747946Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways
Q90539112Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease
Q92849110Response by Fotakis et al to Letter Regarding Article, "Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques"
Q28275533Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family
Q28573871Role of protein kinase C on the expression of platelet-derived growth factor and endothelin-1 in the retina of diabetic rats and cultured retinal capillary pericytes
Q33642252Rosiglitazone inhibits acyl-CoA synthetase activity and fatty acid partitioning to diacylglycerol and triacylglycerol via a peroxisome proliferator-activated receptor-gamma-independent mechanism in human arterial smooth muscle cells and macrophages.
Q34769986S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation
Q37281416SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP.
Q89013999Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome
Q91271562TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells
Q33612986Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis
Q113757260The Remnant Lipoprotein Hypothesis of Diabetes-Associated Cardiovascular Disease
Q73094488The cyclin-dependent kinase pathway moves forward
Q33789390The p75 neurotrophin receptor is required for the major loss of sympathetic nerves from islets under autoimmune attack
Q36883079Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.
Q35881759Uncomplicating the Macrovascular Complications of Diabetes: The 2014 Edwin Bierman Award Lecture
Q34200732Unique proteomic signatures distinguish macrophages and dendritic cells
Q36867436VASP increases hepatic fatty acid oxidation by activating AMPK in mice.

Q118213492Valerie Z. Walldoctoral advisorP184
Q118213614A Cell-Type Specific Approach to Assess the Contribution of Dysregulated Nutrient Handling to Atherosclerosisthesis committee memberP9161

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