A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis

scientific article published on 15 November 2017

A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2017.10.012
P932PMC publication ID5785558
P698PubMed publication ID29154962

P50authorPeter TontonozQ62569518
Karin E. BornfeldtQ87887672
Farah KramerQ125299327
P2093author name stringCharles E Alpers
Kelly L Hudkins
Jenny E Kanter
Jinkuk Choi
Anna Batorsky
P2860cites workLXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptorQ24656186
Molecular mechanisms of diabetic kidney diseaseQ27003963
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene deliveryQ29615235
The effect of CCR2 inhibitor CCX140-B on residual albuminuria in patients with type 2 diabetes and nephropathy: a randomised trial.Q50867968
Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease.Q51140451
Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.Q51552683
Mouse models of diabetic nephropathyQ83665875
Macrophage accumulation in human progressive diabetic nephropathyQ83935710
The pathobiology of diabetic complications: a unifying mechanismQ29617766
Leukocyte recruitment and vascular injury in diabetic nephropathyQ30439127
In vitro and in vivo gene therapy vector evolution via multispecies interbreeding and retargeting of adeno-associated virusesQ33327474
Effects of lowering LDL cholesterol on progression of kidney diseaseQ33974663
Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in miceQ33992107
Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative miceQ34142722
BTBR Ob/Ob mutant mice model progressive diabetic nephropathyQ34455365
The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trialQ34630074
The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteinsQ35233650
BTBR ob/ob mice as a novel diabetic neuropathy model: Neurological characterization and gene expression analysesQ35558662
FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptorsQ35647668
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.Q35849515
Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 DiabetesQ36063184
The phenotypes of podocytes and parietal epithelial cells may overlap in diabetic nephropathyQ36299942
Kidney disease and increased mortality risk in type 2 diabetesQ36574770
Lipid changes and statins in chronic renal insufficiencyQ36665911
Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterolQ36702427
Reversibility of structural and functional damage in a model of advanced diabetic nephropathyQ36977327
Temporal trends in the prevalence of diabetic kidney disease in the United StatesQ37064114
Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysisQ37166321
Diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: advances and contributionsQ37333543
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
Noninvasive imaging of retinal morphology and microvasculature in obese mice using optical coherence tomography and optical microangiographyQ37596809
Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathyQ37603244
Estimating podocyte number and density using a single histologic sectionQ37733611
Targeting inflammation in diabetic kidney disease: early clinical trialsQ38857166
Executive Summary: Heart Disease and Stroke Statistics--2016 Update: A Report From the American Heart AssociationQ40061255
Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis developmentQ41088301
Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial diseaseQ41533607
Induction of atherosclerosis in mice and hamsters without germline genetic engineering.Q42228460
Effect of lipid reduction on the progression of renal disease: a meta-analysisQ43514434
Atherosclerosis susceptibility differences among progenitors of recombinant inbred strains of mice.Q44059065
Macrophages in mouse type 2 diabetic nephropathy: correlation with diabetic state and progressive renal injuryQ44692955
Increase in serum amyloid a evoked by dietary cholesterol is associated with increased atherosclerosis in miceQ44995472
Macrophages in streptozotocin-induced diabetic nephropathy: potential role in renal fibrosisQ45170289
Blockade of CCL2/CCR2 signalling ameliorates diabetic nephropathy in db/db miceQ45232179
Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated miceQ46865455
Plasma Triglycerides and HDL-C Levels Predict the Development of Diabetic Kidney Disease in Subjects With Type 2 Diabetes: The AMD Annals Initiative.Q50227786
P407language of work or nameEnglishQ1860
P921main subjecttype 2 diabetesQ3025883
atherosclerosisQ12252367
P577publication date2017-11-15
P1433published inThe American Journal of PathologyQ4744259
P1476titleA Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis

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cites work (P2860)
Q89967822Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes
Q50102325Novel Reversible Model of Atherosclerosis and Regression Using Oligonucleotide Regulation of the LDL Receptor
Q92620845To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway

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