| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2016PLoSO..1158316V |
| P356 | DOI | 10.1371/JOURNAL.PONE.0158316 |
| P932 | PMC publication ID | 4924840 |
| P698 | PubMed publication ID | 27351842 |
| P50 | author | Jenny E Kanter | Q52684544 |
| Karin E. Bornfeldt | Q87887672 | ||
| Farah Kramer | Q125299327 | ||
| P2093 | author name string | Richard M Breyer | |
| Shelley Barnhart | |||
| Katrin I Andreasson | |||
| Sara N Vallerie | |||
| P2860 | cites work | Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation | Q24313175 |
| Regulation of immune responses by prostaglandin E2 | Q26849305 | ||
| Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes | Q28299458 | ||
| Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse | Q28361862 | ||
| CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs | Q28594485 | ||
| Elevated glucose and diabetes promote interleukin-12 cytokine gene expression in mouse macrophages | Q30439419 | ||
| PGE2 induces IL-6 in orbital fibroblasts through EP2 receptors and increased gene promoter activity: implications to thyroid-associated ophthalmopathy | Q30994732 | ||
| Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages | Q33564601 | ||
| Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice | Q33607097 | ||
| Testing the role of myeloid cell glucose flux in inflammation and atherosclerosis | Q33612986 | ||
| miR33 inhibition overcomes deleterious effects of diabetes mellitus on atherosclerosis plaque regression in mice. | Q34324735 | ||
| Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions | Q34410269 | ||
| Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors | Q34429724 | ||
| Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway | Q34503208 | ||
| Deletion of EP4 on Bone Marrow–Derived Cells Enhances Inflammation and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation | Q34514569 | ||
| S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation | Q34769986 | ||
| Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis. | Q35029268 | ||
| Diabetes adversely affects macrophages during atherosclerotic plaque regression in mice | Q35043471 | ||
| Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficien | Q35088381 | ||
| COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes | Q35199315 | ||
| Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages | Q35612957 | ||
| EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis | Q35800476 | ||
| Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. | Q35849515 | ||
| PTGS-2-PTGER2/4 signaling pathway partially protects from diabetogenic toxicity of streptozotocin in mice | Q36047526 | ||
| Differential stem- and progenitor-cell trafficking by prostaglandin E2. | Q36711496 | ||
| Prostaglandin E receptors | Q36747756 | ||
| Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion | Q36867528 | ||
| Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia | Q36916418 | ||
| Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis | Q37039326 | ||
| Relationship of glycated albumin to blood glucose and HbA1c values and to retinopathy, nephropathy, and cardiovascular outcomes in the DCCT/EDIC study | Q37403310 | ||
| Monocytes from patients with type 1 diabetes spontaneously secrete proinflammatory cytokines inducing Th17 cells | Q37405753 | ||
| Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions | Q37486465 | ||
| Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis | Q37711215 | ||
| Inflammation and diabetes-accelerated atherosclerosis: myeloid cell mediators. | Q38059912 | ||
| Th17 cells in type 1 diabetes | Q38068028 | ||
| The prostanoid EP4 receptor and its signaling pathway. | Q38115283 | ||
| CCR7-specific migration to CCL19 and CCL21 is induced by PGE(2) stimulation in human monocytes: Involvement of EP(2)/EP(4) receptors activation | Q39834801 | ||
| Dual ligand stimulation of RAW 264.7 cells uncovers feedback mechanisms that regulate TLR-mediated gene expression | Q40230374 | ||
| Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis. | Q40791385 | ||
| Renal excretion of prostaglandin E2 and plasma renin activity in type I diabetes mellitus: relationship to normoglycemia achieved with artificial pancreas | Q41430491 | ||
| Plasma prostaglandins: 6-keto-PGF1 alpha, TXB2 and PGE2 in juvenile-onset diabetes determined by high-pressure liquid chromatography and radio-immunoassay | Q41444770 | ||
| Chronic administration of EP4-selective agonist exacerbates albuminuria and fibrosis of the kidney in streptozotocin-induced diabetic mice through IL-6. | Q41987509 | ||
| Early growth response factor-1 mediates prostaglandin E2-dependent transcriptional suppression of cytokine-induced tumor necrosis factor-alpha gene expression in human macrophages and rheumatoid arthritis-affected synovial fibroblasts | Q42819510 | ||
| Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor | Q44127968 | ||
| Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases | Q44302127 | ||
| Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. | Q44436559 | ||
| Prostaglandin E2 receptors EP2 and EP4 are up-regulated in peritoneal macrophages and joints of pristane-treated mice and modulate TNF-alpha and IL-6 production | Q44838313 | ||
| Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL. | Q45161321 | ||
| Elevated plasma prostaglandins and acetylated histone in monocytes in Type 1 diabetes patients. | Q46112558 | ||
| Up-regulation of interleukin-6 induced by prostaglandin E from invading macrophages following nerve injury: an in vivo and in vitro study | Q46442465 | ||
| A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. | Q46662600 | ||
| Prostaglandin E(2) regulates murine hematopoietic stem/progenitor cells directly via EP4 receptor and indirectly through mesenchymal progenitor cells. | Q50765181 | ||
| PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis. | Q51486884 | ||
| Plasma level of 13,14-dihydro-15-keto-PGE2 in patients with diabetic ketoacidosis and in normal fasting subjects. | Q51632917 | ||
| Generation of a conditional allele of the mouse prostaglandin EP4 receptor. | Q52559913 | ||
| PGE2 differentially regulates monocyte-derived dendritic cell cytokine responses depending on receptor usage (EP2/EP4). | Q54455253 | ||
| NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis | Q56991358 | ||
| Role of bone-marrow- and non-bone-marrow-derived receptor for advanced glycation end-products (RAGE) in a mouse model of diabetes-associated atherosclerosis | Q61514318 | ||
| Increased prostaglandin synthesis in childhood diabetes mellitus | Q67469715 | ||
| Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages | Q72571733 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | type-1 diabetes | Q124407 |
| prostaglandin E2 | Q416554 | ||
| P304 | page(s) | e0158316 | |
| P577 | publication date | 2016-06-28 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes | |
| P478 | volume | 11 |
| Q46350486 | A Novel Type 2 Diabetes Mouse Model of Combined Diabetic Kidney Disease and Atherosclerosis |
| Q89769324 | Eicosanoids: Atherosclerosis and cardiometabolic health |
| Q89967822 | Monocytes and Macrophages as Protagonists in Vascular Complications of Diabetes |
| Q46357619 | Prostaglandin E receptor-4 receptor mediates endothelial barrier-enhancing and anti-inflammatory effects of oxidized phospholipids |
| Q50130514 | Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice |
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