Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficien

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Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficien is …
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scholarly articleQ13442814

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P356DOI10.2353/AJPATH.2006.051009
P932PMC publication ID1606621
P698PubMed publication ID16723719
P5875ResearchGate publication ID7058617

P50authorKarin E. BornfeldtQ87887672
Farah KramerQ125299327
P2093author name stringKazuhiro Oka
Stephen M Schwartz
Lawrence Chan
Shelley Barnhart
Fredrik Johansson
Michael E Rosenfeld
Bardia Askari
Patti Polinsky
Erin D MacDougall
Rebecca Varon
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Diet-induced atherosclerosis and experimental hypertension in stumptail Macaques (Macaca Arctoides) Effects of antihypertensive drugs and a non-atherogenic diet in the evolution of lesionsQ39605272
Overview of studies on regression of atherosclerosis.Q40309023
Overexpression of IL-18 decreases intimal collagen content and promotes a vulnerable plaque phenotype in apolipoprotein-E-deficient miceQ40506477
In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regressionQ41724329
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The development of calcium deposits in atherosclerotic lesions and their persistence after lipid regressionQ43688410
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Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE.Q43843334
Characteristics of intact and ruptured atherosclerotic plaques in brachiocephalic arteries of apolipoprotein E knockout miceQ43989979
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Relation Between Progression and Regression of Atherosclerotic Left Main Coronary Artery Disease and Serum Cholesterol Levels as Assessed With Serial Long-Term (≥12 Months) Follow-Up Intravascular UltrasoundQ44659628
Intraplaque hemorrhage and progression of coronary atheromaQ44688413
Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trialQ44783935
Serial studies of mouse atherosclerosis by in vivo magnetic resonance imaging detect lesion regression after correction of dyslipidemia.Q44980739
Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemiaQ44990101
Apolipoprotein E promotes the regression of atherosclerosis independently of lowering plasma cholesterol levelsQ45182834
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Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.Q47924135
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Plaque Neovascularization Is Increased in Ruptured Atherosclerotic Lesions of Human AortaQ56986958
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Increased vulnerability of pre-existing atherosclerosis in ApoE-deficient mice following adenovirus-mediated Fas ligand gene transferQ64378618
Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in miceQ64381202
Rapid regression of atherosclerosis induced by liver-directed gene transfer of ApoE in ApoE-deficient miceQ64381279
A study of atherosclerosis regression in Macaca mulatta. IV. Changes in coronary arteries from animals with atherosclerosis induced for 19 months and then regressed for 24 or 48 months at plasma cholesterol concentrations of 300 or 200 mg/dlQ70793807
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Long-term induction and regression of diet-induced atherosclerotic lesions in rhesus monkeys. II. Morphometric evaluation of lesions by light microscopy in coronary and carotid arteriesQ72858565
Intimal deposition of functional von Willebrand factor in atherogenesisQ73083067
Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouseQ73295343
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P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)2064-2073
P577publication date2006-06-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleAggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficien
P478volume168

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