S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation

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S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCULATIONAHA.110.985523
P932PMC publication ID3072335
P698PubMed publication ID21382888
P5875ResearchGate publication ID50304033

P50authorKarin E. BornfeldtQ87887672
P2093author name stringXin Li
Clemens Sorg
Jay W Heinecke
Claus Kerkhoff
Jessica A Hamerman
Lev Becker
Michelle M Averill
Renee C Leboeuf
Shelley Barnhart
P2860cites workLoss of S100A9 (MRP14) results in reduced interleukin-8-induced CD11b surface expression, a polarized microfilament system, and diminished responsiveness to chemoattractants in vitroQ24540945
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceQ24617743
Myeloid-related protein-8/14 is critical for the biological response to vascular injuryQ24627504
Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 proteinQ24641894
Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI ...Q24650933
Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular eventsQ28238975
Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shockQ28244377
S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end productsQ28276090
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feedingQ33337750
Calprotectin--a novel marker of obesityQ33510158
Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligandsQ33556567
A macrophage sterol-responsive network linked to atherogenesisQ33945439
MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death programQ34580601
The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritisQ34897380
Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed miceQ37465299
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
Inflammation-associated S100 proteins: new mechanisms that regulate function.Q37705110
The arachidonic acid-binding protein S100A8/A9 promotes NADPH oxidase activation by interaction with p67phox and Rac-2.Q38332208
S100A9 is not essential for disease expression in an acute (K/BxN) or chronic (CIA) model of inflammatory arthritisQ40425404
Regulation of S100A8 by glucocorticoids.Q40460702
Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice.Q41528800
Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end productsQ42414162
GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesionsQ42577780
Dietary cholesterol worsens adipose tissue macrophage accumulation and atherosclerosis in obese LDL receptor-deficient miceQ42592049
Il-10 up-regulates macrophage expression of the S100 protein S100A8.Q43600962
Upregulation of S100 calcium-binding protein A9 is required for induction of smooth muscle cell proliferation by a periodontal pathogenQ44928454
The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell-cell contactsQ45731734
Interleukin-10 influences the expression of MRP8 and MRP14 in human dendritic cellsQ47446130
Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins of the S100 family, are secreted by activated monocytes via a novel, tubulin-dependent pathwayQ57189369
Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental SepsisQ63359105
Mouse MRP8 and MRP14, two intracellular calcium-binding proteins associated with the development of the myeloid lineageQ67895960
Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritisQ73401314
Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuliQ73923353
Myeloid-related protein 8/14 complex is released by monocytes and granulocytes at the site of coronary occlusion: a novel, early, and sensitive marker of acute coronary syndromesQ80043875
An increased MRP8/14 expression and adhesion, but a decreased migration towards proinflammatory chemokines of type 1 diabetes monocytesQ80938458
High levels of myeloid-related protein 14 in human atherosclerotic plaques correlate with the characteristics of rupture-prone lesionsQ84060206
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
atherosclerosisQ12252367
P304page(s)1216-1226
P577publication date2011-03-07
P1433published inCirculationQ578091
P1476titleS100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation
P478volume123

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cites work (P2860)
Q52684469A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome.
Q89810882Ablation of Myeloid Cell MRP8 Ameliorates Nephrotoxic Serum-induced Glomerulonephritis by Affecting Macrophage Characterization through Intraglomerular Crosstalk
Q45023594Association of calprotectin with leukocyte chemotactic and inflammatory mediators following acute aerobic exercise.
Q59360003BVDV Npro protein mediates the BVDV induced immunosuppression through interaction with cellular S100A9 protein
Q45720028Biomarkers in COPD: is mortality the Holy Grail?
Q55342042Blocking the interaction between S100A9 protein and RAGE V domain using S100A12 protein.
Q39022858Calprotectin in rheumatic diseases
Q90179667Calprotectin protects against experimental colonic inflammation in mice
Q35102753Changes of dendritic cells and fractalkine in type 2 diabetic patients with unstable angina pectoris: a preliminary report
Q53010078Chronic liver inflammation and hepatocellular carcinogenesis are independent of S100A9.
Q35849515Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Q47176170Differential association of S100A9, an inflammatory marker, and p53, a cell cycle marker, expression with epicardial adipocyte size in patients with cardiovascular disease
Q36558881Endothelial acyl-CoA synthetase 1 is not required for inflammatory and apoptotic effects of a saturated fatty acid-rich environment
Q92773391Enhanced myelopoiesis and aggravated arthritis in S100a8-deficient mice
Q36261057Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells
Q37001259Functions of S100 proteins.
Q27316270Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner
Q37711215Hyperglycemia promotes myelopoiesis and impairs the resolution of atherosclerosis
Q35947472In vivo targeting of inflammation-associated myeloid-related protein 8/14 via gadolinium immunonanoparticles.
Q35751879Loss of myeloid related protein-8/14 exacerbates cardiac allograft rejection
Q35063189Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins
Q38125279Molecular biology of atherosclerosis
Q36169181Multiple Evolutionary Origins of Ubiquitous Cu2+ and Zn2+ Binding in the S100 Protein Family
Q50079976MyD88-dependent dendritic and epithelial cell crosstalk orchestrates immune responses to allergens
Q36063184Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes
Q64235528Neutrophil-Derived MRP14 Supports Plasma Cell Commitment and Protects Myeloma Cells from Apoptosis
Q26852048Neutrophils in atherosclerosis: from mice to man
Q38629718Neutrophils produce interleukin 17A (IL-17A) in a dectin-1- and IL-23-dependent manner during invasive fungal infection.
Q38033682Novel insights into the role of S100A8/A9 in skin biology
Q95840940PE_PGRS31-S100A9 Interaction Promotes Mycobacterial Survival in Macrophages Through the Regulation of NF-κB-TNF-α Signaling and Arachidonic Acid Metabolism
Q26747410Resolution of Inflammation: What Controls Its Onset?
Q38725622Review of Rosai-Dorfman Disease: New Insights into the Pathogenesis of This Rare Disorder
Q36333169Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells
Q42717904Runx2 Deletion in Smooth muscle Cells Inhibits Vascular Osteochondrogenesis and Calcification but not Atherosclerotic Lesion Formation.
Q49497885S100 Proteins As an Important Regulator of Macrophage Inflammation.
Q35911792S100 calcium binding proteins and ion channels
Q38061123S100 proteins as diagnostic and prognostic markers in colorectal and hepatocellular carcinoma
Q35627729S100/calgranulins EN-RAGEing the blood vessels: implications for inflammatory responses and atherosclerosis
Q36173951S100A12 expression in thoracic aortic aneurysm is associated with increased risk of dissection and perioperative complications
Q27024450S100A8 and S100A9 in cardiovascular biology and disease
Q60044327S100A8 and S100A9 proteins form part of a paracrine feedback loop between pancreatic cancer cells and monocytes
Q37436729S100A8 and S100A9: DAMPs at the crossroads between innate immunity, traditional risk factors, and cardiovascular disease.
Q35568273S100A8/A9 (calprotectin) is critical for development of glomerulonephritis and promotes inflammatory leukocyte-renal cell interactions
Q89927299S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis
Q50019761S100A9 gene silencing inhibits the release of pro-inflammatory cytokines by blocking the IL-17 signalling pathway in mice with acute pancreatitis.
Q35624711S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis
Q89013999Smooth muscle glucose metabolism promotes monocyte recruitment and atherosclerosis in a mouse model of metabolic syndrome
Q39061766Splenic metabolic activity predicts risk of future cardiovascular events: demonstration of a cardiosplenic axis in humans.
Q21559604Surface acoustic waves enhance neutrophil killing of bacteria
Q35220162TLR9 ligands induce S100A8 in macrophages via a STAT3-dependent pathway which requires IL-10 and PGE2.
Q24307415Target-selective protein S-nitrosylation by sequence motif recognition
Q45396344Targeting the association of calgranulin B (S100A9) with insulin resistance and type 2 diabetes
Q34294433The apolipoprotein-AI mimetic peptide L4F at a modest dose does not attenuate weight gain, inflammation, or atherosclerosis in LDLR-null mice
Q88102825The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion
Q39459619The role of damage- and pathogen-associated molecular patterns in inflammation-mediated vulnerability of atherosclerotic plaques
Q48175299The role of monocytosis and neutrophilia in atherosclerosis
Q38777795Tumor-derived factors modulating dendritic cell function
Q39442043UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance
Q92072946Weighted Gene Co-Expression Network Analysis Identifies Critical Genes in the Development of Heart Failure After Acute Myocardial Infarction

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