scholarly article | Q13442814 |
P50 | author | Lucy Golden-Mason | Q47412530 |
Vijay Kuchroo | Q87889159 | ||
P2093 | author name string | Brent E Palmer | |
Hugo R Rosen | |||
Lucy Golden-Mason | |||
Brian J McMahon | |||
Nasim Kassam | |||
David R Gretch | |||
Lisa Townshend-Bulson | |||
Nicole Castelblanco | |||
Stephen Livingston | |||
P2860 | cites work | Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus | Q27469800 |
PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion | Q27477628 | ||
Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression | Q27478366 | ||
Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction | Q27481027 | ||
Global epidemiology of hepatitis C virus infection | Q27860799 | ||
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions | Q28146072 | ||
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity | Q28281686 | ||
Three-color flow cytometry detection of intracellular cytokines in peripheral blood mononuclear cells: comparative analysis of phorbol myristate acetate-ionomycin and phytohemagglutinin stimulation | Q28359797 | ||
Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells | Q28754733 | ||
Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection | Q29620795 | ||
Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression | Q34118755 | ||
PD-1 and its ligands in T-cell immunity | Q36791446 | ||
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection | Q36979967 | ||
Novel strategies to eliminate persistent viral infections | Q37079434 | ||
Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection | Q37728408 | ||
TIMs: central regulators of immune responses | Q42287215 | ||
Cutting edge: programmed death-1 expression is increased on immunocytes in chronic hepatitis C virus and predicts failure of response to antiviral therapy: race-dependent differences | Q42977043 | ||
Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells | Q42982580 | ||
Differential antigenic hierarchy associated with spontaneous recovery from hepatitis C virus infection: implications for vaccine design | Q43001324 | ||
Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence | Q43032677 | ||
Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: correlation with clinical disease stages | Q43036009 | ||
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections | Q45733084 | ||
Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin | Q48053615 | ||
Prospective analysis of effector and regulatory CD4+ T cells in chronic HCV patients undergoing combination antiviral therapy. | Q50568011 | ||
Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction | Q80641790 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | virus | Q808 |
Hepatitis C virus | Q708693 | ||
hepatitis C | Q154869 | ||
overexpression | Q61643320 | ||
P304 | page(s) | 9122-9130 | |
P577 | publication date | 2009-07-08 | |
P1433 | published in | Journal of Virology | Q1251128 |
P1476 | title | Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells | |
P478 | volume | 83 |
Q28553032 | A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation |
Q24301928 | A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection |
Q41980551 | A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are major sheddases of T cell immunoglobulin and mucin domain 3 (Tim-3) |
Q28542702 | A regulatory polymorphism in HAVCR2 modulates susceptibility to HIV-1 infection |
Q37898079 | A spatial view of the CD8+ T-cell response: the case of HCV. |
Q35835755 | Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. |
Q47556597 | Acute Stimulation Generates Tim-3-expressing Th1-type CD4 T Cells That Persist In Vivo and Show Enhanced Effector Function |
Q37805839 | Adaptive Immunity to the Hepatitis C Virus |
Q37682489 | Adaptive immune response during hepatitis C virus infection. |
Q26753195 | Adaptive immunity in the liver |
Q37973905 | Adaptive immunity to Anaplasma pathogens and immune dysregulation: implications for bacterial persistence |
Q28483967 | Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children |
Q36068258 | Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs |
Q35031602 | An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction |
Q40956750 | An increased number of PD-1+ and Tim-3+ CD8+ T cells is involved in immune evasion in gastric cancer |
Q35178139 | Analysis of monocytic and granulocytic myeloid-derived suppressor cells subsets in patients with hepatitis C virus infection and their clinical significance |
Q30637447 | AntiCD3Fv fused to human interleukin-3 deletion variant redirected T cells against human acute myeloid leukemic stem cells |
Q49785595 | Antitumor effect of membrane-type Tim-3 on hepatocellular carcinoma Hepa1-6 cells of ICR mice |
Q36193004 | Apoptosis of tumor infiltrating effector TIM-3+CD8+ T cells in colon cancer |
Q33670670 | Association of T-cell immunoglobulin and mucin domain-containing molecule 3 (Tim-3) polymorphisms with susceptibility and disease progression of HBV infection |
Q36377233 | Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion. |
Q26782799 | Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators |
Q43426048 | Blockade of Tim-3 signaling restores the virus-specific CD8⁺ T-cell response in patients with chronic hepatitis B. |
Q35679577 | Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence |
Q40536621 | CD14+ monocyte-derived galectin-9 induces natural killer cell cytotoxicity in chronic hepatitis C. |
Q37495787 | CD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells |
Q33718778 | CD8(+) T-Cell Responses in Acute Hepatitis C Virus Infection. |
Q33408423 | Characteristics of splenic CD8+ T cell exhaustion in patients with hepatitis C. |
Q36665452 | Characterization of age-associated exhausted CD8⁺ T cells defined by increased expression of Tim-3 and PD-1. |
Q36299762 | Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer |
Q39000980 | Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection. |
Q39761212 | Co-inhibitory molecules: Controlling the effectors or controlling the controllers? |
Q42369857 | Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer. |
Q42239888 | Comparison of dynamic expressions of Tim-3 and PD-1 in the brains between toxoplasmic encephalitis-resistant BALB/c and -susceptible C57BL/6 mice |
Q36016560 | Contact-dependent interference with invariant NKT cell activation by herpes simplex virus-infected cells |
Q34093225 | Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection |
Q27490355 | Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C |
Q39987703 | DNA demethylation of the TIM-3 promoter is critical for its stable expression on T cells |
Q100385905 | Decrease of T-cells exhaustion markers programmed cell death-1 and T-cell immunoglobulin and mucin domain-containing protein 3 and plasma IL-10 levels after successful treatment of chronic hepatitis C |
Q40042407 | Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection |
Q36760150 | Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection |
Q33916693 | Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells |
Q42282987 | Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection. |
Q42240917 | Effect of the infectious dose and the presence of hepatitis C virus core gene on mouse intrahepatic CD8 T cells |
Q37893320 | Emerging Tim-3 functions in antimicrobial and tumor immunity |
Q38806960 | Emerging role of immunotherapy in urothelial carcinoma-Future directions and novel therapies |
Q30420186 | Enhanced Tim3 activity improves survival after influenza infection |
Q34100837 | Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with Chlamydia muridarum |
Q34033862 | Enhancement of SIV-specific cell mediated immune responses by co-administration of soluble PD-1 and Tim-3 as molecular adjuvants in mice |
Q45362051 | Exhausted or just sleeping: awakening virus-specific responses in chronic hepatitis C virus infection |
Q34550643 | Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques |
Q99400630 | Expression of Inhibitory Receptors on T and NK Cells Defines Immunological Phenotypes of HCV Patients with Advanced Liver Fibrosis |
Q34699537 | Expression of a broad array of negative costimulatory molecules and Blimp-1 in T cells following priming by HIV-1 pulsed dendritic cells |
Q93019262 | Expression of programmed cell death protein 1 and T-cell immunoglobulin- and mucin-domain-containing molecule-3 on peripheral blood CD4+CD8+ double positive T cells in patients with chronic hepatitis C virus infection and in subjects who spontaneous |
Q37964746 | Failure of innate and adaptive immune responses in controlling hepatitis C virus infection |
Q64100514 | FcγR-Binding Is an Important Functional Attribute for Immune Checkpoint Antibodies in Cancer Immunotherapy |
Q33941340 | Features of responding T cells in cancer and chronic infection. |
Q43119125 | Follicular CD8+ T Cells: Origin, Function and Importance during HIV Infection. |
Q37284860 | Functional Characteristics of the Gut Microbiome in C57BL/6 Mice Differentially Susceptible to Plasmodium yoelii |
Q34789276 | Galectin-9 and IL-21 mediate cross-regulation between Th17 and Treg cells during acute hepatitis C. |
Q35986628 | Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection |
Q55285607 | Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions. |
Q38316374 | Galectin-9 regulates T helper cell function independently of Tim-3. |
Q27314881 | Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response |
Q33923368 | Galectin-9: Diverse roles in hepatic immune homeostasis and inflammation |
Q36055483 | Generalized Liver- and Blood-Derived CD8+ T-Cell Impairment in Response to Cytokines in Chronic Hepatitis C Virus Infection |
Q30402699 | Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time |
Q40947997 | HCV-infected cells and differentiation increase monocyte immunoregulatory galectin-9 production. |
Q92134294 | HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules |
Q42998454 | HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression |
Q37462730 | HCV-specific interleukin-21+CD4+ T cells responses associated with viral control through the modulation of HCV-specific CD8+ T cells function in chronic hepatitis C patients. |
Q36760035 | HIV-specific CD8+ T cells from elite controllers are primed for survival. |
Q57038997 | HSV-1 latency and the kinetics of reactivation are regulated by a complex network of interactions between HVEM, its ligands (gD, BTLA, LIGHT and CD160) and LAT |
Q24607794 | HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications |
Q37106235 | Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection |
Q38807353 | Hepatitis A virus cellular receptor 2 (HAVCR2) is decreased with viral infection and regulates pro-labour mediators OA. |
Q65002126 | Hepatitis C Virus Genetic Variability, Human Immune Response, and Genome Polymorphisms: Which Is the Interplay? |
Q38036576 | Hepatitis C virus-mediated modulation of cellular immunity |
Q26750792 | Host nucleotide polymorphism in hepatitis B virus-associated hepatocellular carcinoma |
Q37676100 | How chronic viral infections impact on antigen-specific T-cell responses |
Q34374800 | IL-10 mediated regulation of liver inflammation during acute murine cytomegalovirus infection |
Q35858092 | IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma |
Q92249477 | IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors |
Q26765459 | Immune Checkpoint Modulators: An Emerging Antiglioma Armamentarium |
Q38853678 | Immune Response and Mortality Risk Relate to Distinct Lung Microbiomes in Patients with HIV and Pneumonia |
Q47554770 | Immune checkpoint inhibition: prospects for prevention and therapy of hepatocellular carcinoma. |
Q53685582 | Immune checkpoint receptors: homeostatic regulators of immunity. |
Q38020961 | Immune checkpoints in central nervous system autoimmunity. |
Q34178628 | Immune control and failure in HCV infection--tipping the balance |
Q33750375 | Immune derangement occurs in patients with H7N9 avian influenza |
Q38334024 | Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees. |
Q52348457 | Immune regulation by Tim-3. |
Q38902559 | Immune regulation in chronic hepatitis C virus infection |
Q38885002 | Immune responses and immunopathology in acute and chronic viral hepatitis |
Q26866955 | Immune responses to HCV and other hepatitis viruses |
Q37137360 | Immune suppression in tumors as a surmountable obstacle to clinical efficacy of cancer vaccines |
Q34291105 | Immunization with Different Viral Antigens Alters the Pattern of T Cell Exhaustion and Latency in Herpes Simplex Virus Type 1-Infected Mice |
Q39262779 | Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses |
Q42024872 | Immunotherapy of hepatocellular carcinoma: Unique challenges and clinical opportunities |
Q39090226 | Impaired functional responses in follicular lymphoma CD8+TIM-3+ T lymphocytes following TCR engagement. |
Q34960553 | Impaired hepatitis B vaccine responses during chronic hepatitis C infection: involvement of the PD-1 pathway in regulating CD4(+) T cell responses |
Q36237064 | Increased bovine Tim-3 and its ligand expressions during bovine leukemia virus infection |
Q35123912 | Increased frequency of Tim-3 expressing T cells is associated with symptomatic West Nile virus infection |
Q36103979 | Increased program cell death-1 expression on T lymphocytes of patients with progressive multifocal leukoencephalopathy |
Q41856139 | Induction of Multiple Immune Regulatory Pathways with Differential Impact in HCV/HIV Coinfection |
Q37402534 | Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells |
Q35783318 | Inhibitory Receptors Beyond T Cell Exhaustion. |
Q38206528 | Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy? |
Q41035955 | Innate and Adaptive Immune Responses in Chronic HCV Infection |
Q34073021 | Innate immune function in placenta and cord blood of hepatitis C--seropositive mother-infant dyads |
Q38837469 | Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation. |
Q37625429 | Liver environment and HCV replication affect human T-cell phenotype and expression of inhibitory receptors |
Q30409150 | Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice |
Q34343795 | Loss and dysfunction of Vδ2⁺ γδ T cells are associated with clinical tolerance to malaria |
Q40414240 | Memory re-differentiation and reduced lymphocyte activation in chronic HCV-infected patients receiving direct-acting antivirals. |
Q38899741 | MicroRNA-155 regulates interferon-γ production in natural killer cells via Tim-3 signalling in chronic hepatitis C virus infection |
Q55400314 | Model of the adaptive immune response system against HCV infection reveals potential immunomodulatory agents for combination therapy. |
Q26744635 | Modulation of Innate Immune Mechanisms to Enhance Leishmania Vaccine-Induced Immunity: Role of Coinhibitory Molecules |
Q40461629 | Molecular characterization of T-cell immunoglobulin mucin domain-3 and Galectin-9 genes of swamp- and riverine-type water buffaloes. |
Q38091548 | Molecular signatures of T-cell inhibition in HIV-1 infection |
Q28086907 | Mutational escape of CD8+ T cell epitopes: implications for prevention and therapy of persistent hepatitis virus infections |
Q34505690 | Natural Killer Cells in Viral Hepatitis |
Q36509345 | Negative CD4 + TIM-3 signaling confers resistance against cold preservation damage in mouse liver transplantation |
Q56889626 | Not All Immune Checkpoints Are Created Equal |
Q57049820 | Notch2-dependent DC2s mediate splenic germinal center responses |
Q64885088 | Observed Changes in Natural Killer and T cell Phenotypes with Evaluation of Immune Outcome in a Longitudinal Cohort Following Sofosbuvir-Based Therapy for Chronic Hepatitis C Infection. |
Q34603687 | Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus |
Q56892392 | Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes |
Q37706634 | Overexpression of herpes simplex virus glycoprotein K (gK) alters expression of HSV receptors in ocularly-infected mice |
Q36194853 | PD-1 and BTLA and CD8(+) T-cell "exhaustion" in cancer: "Exercising" an alternative viewpoint |
Q35649732 | PD-1 and Tim-3 Pathways Regulate CD8+ T Cells Function in Atherosclerosis |
Q36346893 | PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy |
Q91636348 | PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4+ and CD8+ T Cells During BVDV Infection in vitro |
Q35786326 | Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells |
Q37046087 | Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults |
Q40997923 | Plasma soluble Tim-3 emerges as an inhibitor in sepsis: sepsis contrary to membrane Tim-3 on monocytes |
Q35883043 | Positive and negative regulation of cellular immune responses in physiologic conditions and diseases |
Q97527205 | Producing Soluble Human Programmed Cell Death Protein-1: A Natural Supporter for CD4+T Cell Cytotoxicity and Tumor Cells Apoptosis |
Q26781481 | Programmed death-1/programmed death-L1 signaling pathway and its blockade in hepatitis C virus immunotherapy |
Q54995947 | Receptors That Inhibit Macrophage Activation: Mechanisms and Signals of Regulation and Tolerance. |
Q34772857 | Reduced naive CD4 T cell numbers and impaired induction of CD27 in response to T cell receptor stimulation reflect a state of immune activation in chronic hepatitis C virus infection |
Q40475655 | Regulation of HBV-specific CD8(+) T cell-mediated inflammation is diversified in different clinical presentations of HBV infection. |
Q34017074 | Regulation of T cell responses by the receptor molecule Tim-3. |
Q37700859 | Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection |
Q64966359 | Restoration of HCV-Specific Immune Responses with Antiviral Therapy: A Case for DAA Treatment in Acute HCV Infection. |
Q42978256 | Reversal of nonstructural protein 3-specific CD4(+) T cell dysfunction in patients with persistent hepatitis C virus infection |
Q26768530 | Role of Tim-3 in hepatitis B virus infection: An overview |
Q41013010 | Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication |
Q41087941 | Roles of the programmed cell death 1, T cell immunoglobulin mucin-3, and cluster of differentiation 288 pathways in the low reactivity of invariant natural killer T cells after chronic hepatitis B virus infection |
Q58618392 | Sequential monitoring of TIM-3 mRNA expression in blood and urine samples of renal transplant recipients |
Q54944142 | Stimulation of Camel Polyclonal Antibody against Human T cell Immunoglobulin and Mucin 3. |
Q85066472 | Suppression of HIV Replication by Antiretroviral Therapy Reduces TIM-3 Expression on HIV-Specific CD8+ T Cells |
Q37702049 | T cell Ig and mucin domain proteins and immunity |
Q28510998 | T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases |
Q39078341 | T cell exhaustion: from pathophysiological basics to tumor immunotherapy |
Q37385510 | T cell immunoglobulin and mucin domain-containing molecule 3 on CD14+ monocytes serves as a novel biological marker for diabetes duration in type 2 diabetes mellitus |
Q35571333 | T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses. |
Q43182638 | T cell immunopathogenesis and immunotherapeutic strategies for chronic hepatitis B virus infection |
Q27003510 | T cell responses in hepatitis C virus infection: historical overview and goals for future research |
Q37272020 | T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia. |
Q35164131 | T lymphocyte surface expression of exhaustion markers as biomarkers of the efficacy of chemotherapy for tuberculosis |
Q34127437 | T-Cell Dysfunction and Inhibitory Receptors in Hepatitis C Virus Infection |
Q33721890 | T-bet, a Th1 transcription factor regulates the expression of Tim-3. |
Q28083810 | T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance |
Q34102010 | T-cell exhaustion: characteristics, causes and conversion |
Q38514244 | T-cell responses in hepatitis B and C virus infection: similarities and differences |
Q37763998 | TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity |
Q47133354 | TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1. |
Q28117255 | TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway |
Q90723714 | TIM-3 and CEACAM1 do not interact in cis and in trans |
Q37729313 | TIM-3 as a Target for Cancer Immunotherapy and Mechanisms of Action |
Q38138901 | TIM-3 as a novel therapeutic target for eradicating acute myelogenous leukemia stem cells |
Q33761878 | TIM-3 is a potential prognostic marker for patients with solid tumors: A systematic review and meta-analysis |
Q36487481 | TIM-3 regulates innate immune cells to induce fetomaternal tolerance. |
Q56897131 | TIM-3, a Possible Target for Immunotherapy in Cancer and Chronic Viral Infections |
Q35954111 | TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection |
Q91062988 | TIM3 comes of age as an inhibitory receptor |
Q36845835 | TIM3(+)FOXP3(+) regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer |
Q34161493 | Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity |
Q41923721 | Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection |
Q92381606 | The Absence of Lymphotoxin-α, a Herpesvirus Entry Mediator (HVEM) Ligand, Affects Herpes Simplex Virus 1 Infection In Vivo Differently than the Absence of Other HVEM Cellular Ligands |
Q47717100 | The Effect of Inhibitory Signals on the Priming of Drug Hapten-Specific T Cells That Express Distinct Vβ Receptors |
Q30634989 | The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia |
Q44953373 | The Lung Microbiome and Airway Disease |
Q36451717 | The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis |
Q38373689 | The bitter side of sweet: the role of Galectin-9 in immunopathogenesis of viral infections. |
Q36760218 | The frequency of CD127(+) hepatitis C virus (HCV)-specific T cells but not the expression of exhaustion markers predicts the outcome of acute HCV infection. |
Q35193019 | The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism |
Q38171224 | The impact of the TIM gene family on tumor immunity and immunosuppression |
Q83524808 | The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway |
Q36917904 | The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells. |
Q41834044 | The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms |
Q40657449 | The relevance of Tim-3 polymorphisms and F protein to the outcomes of HCV infection |
Q42143302 | The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1. |
Q33412416 | The role of T cell immunoglobulin and mucin domain-3 in immune thrombocytopenia |
Q35928357 | The role of coinhibitory signaling pathways in transplantation and tolerance |
Q34632187 | The role of dendritic cells in viral persistence |
Q26800735 | The role of microenvironment and immunity in drug response in leukemia |
Q34239730 | Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection |
Q84952652 | Thinking inside the box: how T cell inhibitory receptors signal |
Q33909020 | Tim-3 and its role in regulating anti-tumor immunity |
Q36181681 | Tim-3 blocking rescue macrophage and T cell function against Mycobacterium tuberculosis infection in HIV+ patients. |
Q28506567 | Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection |
Q34634058 | Tim-3 expression defines regulatory T cells in human tumors |
Q34364103 | Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity |
Q34704849 | Tim-3 expression on peripheral T cell subsets correlates with disease progression in hepatitis B infection |
Q28586438 | Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock |
Q30432023 | Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection |
Q34335966 | Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection |
Q50125564 | Tim-3, Lag-3, and TIGIT. |
Q36384423 | Tim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions |
Q36586341 | Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease. |
Q45358316 | Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma. |
Q28505971 | Tim3 binding to galectin-9 stimulates antimicrobial immunity |
Q93377252 | Tipping the balance: inhibitory checkpoints in intestinal homeostasis |
Q38236249 | Too much of a good thing? Tim-3 and TCR signaling in T cell exhaustion |
Q40794710 | Type I Interferon Elevates Co-Regulatory Receptor Expression on CMV- and EBV-Specific CD8 T Cells in Chronic Hepatitis C. |
Q82261749 | Up-regulation of Tim-3 expression contributes to development of burn-induced T cell immune suppression in mice |
Q36014245 | Up-regulation of Tim-3 is associated with poor prognosis of patients with colon cancer |
Q35174419 | Up-regulation of Tim-3 on T cells during acute simian immunodeficiency virus infection and on antigen specific responders |
Q35839496 | Update on hepatitis C virus-specific immunity |
Q51063368 | Upregulated expression of Tim-3 involved in the process of toxoplasmic encephalitis in mouse model. |
Q37055901 | Upregulation of TIM-3 and PD-1 on CD4+ and CD8+ T Cells Associated with Dysfunction of Cell-Mediated Immunity after Colorectal Cancer Operation |
Q34161579 | Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients |
Q34462234 | Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. |
Q37657501 | Using EAE to better understand principles of immune function and autoimmune pathology |
Q38223279 | Viral (hepatitis C virus, hepatitis B virus, HIV) persistence and immune homeostasis |
Q38677715 | Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment |