Continuous Combined Estrogen Plus Progestin and Endometrial Cancer: The Women's Health Initiative Randomized Trial

scientific article published on 14 December 2015

Continuous Combined Estrogen Plus Progestin and Endometrial Cancer: The Women's Health Initiative Randomized Trial is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JNCI/DJV350
P932PMC publication ID5072373
P698PubMed publication ID26668177

P50authorJoAnn E. MansonQ6204013
Susan D. ReedQ114942444
P2093author name stringC Chen
B V Howard
J Wactawski-Wende
R Haque
R T Chlebowski
T E Rohan
C A Thomson
G L Anderson
G E Sarto
C D Runowicz
A K Aragaki
M S Simon
P2860cites workRisks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trialQ27860743
Estrogen carcinogenesis in breast cancerQ28292500
Increased Risk of Endometrial Carcinoma among Users of Conjugated EstrogensQ28320364
Long-term postmenopausal hormone therapy and endometrial cancerQ33650188
Progesterone: the ultimate endometrial tumor suppressor.Q33773307
The 2012 Hormone Therapy Position Statement of The North American Menopause SocietyQ34161400
Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized TrialQ34208463
Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: A Systematic Review to Update the U.S. Preventive Services Task Force RecommendationsQ34287536
National use of postmenopausal hormone therapy: annual trends and response to recent evidenceQ34288307
Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effectsQ34317537
Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer.Q34321877
Menopausal hormone therapy and risk of endometrial cancerQ34345110
Endometrial cancer and hormone-replacement therapy in the Million Women StudyQ34415404
Symptom experience after discontinuing use of estrogen plus progestinQ34433581
The contribution of postmenopausal hormone use cessation to the declining incidence of breast cancerQ34555256
Unequal risks for breast cancer associated with different hormone replacement therapies: results from the E3N cohort studyQ34576753
Breast cancer incidence, 1980-2006: combined roles of menopausal hormone therapy, screening mammography, and estrogen receptor statusQ34581334
The decrease in breast-cancer incidence in 2003 in the United StatesQ34620356
Health risks and benefits 3 years after stopping randomized treatment with estrogen and progestinQ34758422
Breast cancer after use of estrogen plus progestin in postmenopausal womenQ34938322
Paradoxical Clinical Effect of Estrogen on Breast Cancer Risk: A “New” Biology of Estrogen-induced ApoptosisQ35002418
Long-term use of continuous-combined estrogen-progestin hormone therapy and risk of endometrial cancerQ35510465
The Epidemiology of Endometrial and Ovarian CancerQ35676052
Fertility-sparing treatment of endometrial cancer: options, outcomes and pitfallsQ35886066
Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women's Health Initiative randomised placebo-controlled trialQ36143058
Is estrogen plus progestin menopausal hormone therapy safe with respect to endometrial cancer risk?Q36189328
Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trialQ36851595
Biological roles of estrogen and progesterone in human endometrial carcinoma--new developments in potential endocrine therapy for endometrial cancerQ36929282
Type I and II endometrial cancers: have they different risk factors?Q36977055
Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit?Q37277121
Reproductive factors and postmenopausal hormone use in relation to endometrial cancer risk in the Nurses' Health Study cohort 1976-2004.Q37442687
Estrogen Plus Progestin and Breast Cancer Incidence and Mortality in Postmenopausal WomenQ37480990
Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trialsQ37658616
Catch it before it kills: progesterone, obesity, and the prevention of endometrial cancerQ37661580
Declining incidence of breast cancer after decreased use of hormone-replacement therapy: magnitude and time lags in different countriesQ37923626
Global consensus statement on menopausal hormone therapy.Q38089075
Menopausal symptoms and treatment-related effects of estrogen and progestin in the Women's Health InitiativeQ39367613
Antitumor action of physiological estradiol on tamoxifen-stimulated breast tumors grown in athymic mice.Q40879219
Progesterone induces adult mammary stem cell expansionQ42471079
Noncardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II).Q42679385
Menopausal hormone therapy and risk of endometrial carcinoma among postmenopausal women in the European Prospective Investigation Into Cancer and NutritionQ42852626
Menopausal hormone therapy and breast cancer risk: impact of different treatments. The European Prospective Investigation into Cancer and NutritionQ43520576
Risks of endometrial cancer associated with different hormone replacement therapies in the E3N cohort, 1992-2008.Q43781057
Effects of estrogen plus progestin on gynecologic cancers and associated diagnostic procedures: the Women's Health Initiative randomized trialQ44602959
Association of Exogenous Estrogen and Endometrial CarcinomaQ46021645
Impact of weight change and weight cycling on risk of different subtypes of endometrial cancerQ46427223
The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy (CHART study). A randomized controlled trialQ50617188
Histologic alterations in endometrial hyperplasia and well-differentiated carcinoma treated with progestinsQ50970377
Recent changes in endometrial cancer trends among menopausal-age US womenQ51212025
Case-control study of postmenopausal hormone replacement therapy and endometrial cancerQ52930339
Body Mass Index, Hormone Replacement Therapy, and Endometrial Cancer Risk: A Meta-AnalysisQ56525963
Implementation of the women's health initiative study designQ57055364
Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI TrialQ70918505
Hormone replacement therapy with estrogen or estrogen plus medroxyprogesterone acetate is associated with increased epithelial proliferation in the normal postmenopausal breastQ73276429
Endometrial carcinoma risks among menopausal estrogen plus progestin and unopposed estrogen users in a cohort of postmenopausal womenQ80394797
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
endometrial cancerQ944777
P577publication date2015-12-14
P1433published inJournal of the National Cancer InstituteQ400279
P1476titleContinuous Combined Estrogen Plus Progestin and Endometrial Cancer: The Women's Health Initiative Randomized Trial
P478volume108

Reverse relations

cites work (P2860)
Q58804285A study of the application of TAP combined with transvaginal ultrasound in the diagnosis of early-stage endometrial cancer
Q64891209Cancer Progress and Priorities: Uterine Cancer.
Q92500366Chronic Exposure of Mice to Bisphenol-A Alters Uterine Fibroblast Growth Factor Signaling and Leads to Aberrant Epithelial Proliferation
Q59805381Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis
Q52579984Effect of metformin use on the risk and prognosis of endometrial cancer: a systematic review and meta-analysis
Q91909252Effects of hormone therapy on recurrence in endometrial cancer survivors: a nationwide study using the Korean Health Insurance Review and Assessment Service database
Q92795160Estrogen Enhances Endometrial Cancer Cells Proliferation by Upregulation of Prohibitin
Q60728526Exogenous Hormone Use and Endometrial Cancer in U.S. Black Women
Q57689276Hormone replacement therapy for women previously treated for endometrial cancer
Q48516369Hormone therapy as a management strategy for lung metastasis after 5 years of endometrial cancer: A case report and literature review
Q38975101Hormone-replacement therapy: current thinking
Q64108528Increased Incidence of Endometrial Cancer Following the Women's Health Initiative: An Assessment of Risk Factors
Q38976756Intentional Weight Loss and Endometrial Cancer Risk
Q58592781Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Nummer 032/034-OL, April 2018) - Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors o
Q30238978Long-term hormone therapy for perimenopausal and postmenopausal women
Q28077183Major clinical research advances in gynecologic cancer in 2015
Q40045531Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women's Health Initiative Randomized Trials
Q38700757Safety and benefit considerations for menopausal hormone therapy
Q42229710Why women choose compounded bioidentical hormone therapy: lessons from a qualitative study of menopausal decision-making.

Search more.