| scholarly article | Q13442814 |
| P356 | DOI | 10.1172/JCI119309 |
| P8608 | Fatcat ID | release_d37ors3xejbqzneabridav3ipa |
| P932 | PMC publication ID | 507966 |
| P698 | PubMed publication ID | 9119990 |
| P5875 | ResearchGate publication ID | 14098316 |
| P2093 | author name string | Wang H | |
| Malbon CC | |||
| Nuovo GJ | |||
| Sivaraman VS | |||
| P2860 | cites work | Elevated content of the tyrosine kinase substrate phospholipase C-gamma 1 in primary human breast carcinomas | Q24559979 |
| How MAP kinases are regulated | Q28609360 | ||
| Activation of the Ras signalling pathway in human breast cancer cells overexpressing erbB-2 | Q28678734 | ||
| Tyrosine kinase receptor--nuclear protooncogene interactions in breast cancer | Q35271751 | ||
| In situ detection of PCR-amplified HIV-1 nucleic acids and tumor necrosis factor cDNA in cervical tissues. | Q35832863 | ||
| Signal transduction via the MAP kinases: proceed at your own RSK. | Q36381460 | ||
| Agonist regulation of gene expression of adrenergic receptors and G proteins | Q40867496 | ||
| MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts | Q41628329 | ||
| Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts | Q42492215 | ||
| Cancer statistics, 1995. | Q43686273 | ||
| Mammalian beta 1- and beta 2-adrenergic receptors. Immunological and structural comparisons | Q70151267 | ||
| MAP kinase module: role in the control of cell proliferation | Q71992334 | ||
| Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma | Q72388344 | ||
| Raf-1 protein expression in human breast cancer cells | Q72452835 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | breast cancer | Q128581 |
| P304 | page(s) | 1478-1483 | |
| P577 | publication date | 1997-04-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Hyperexpression of mitogen-activated protein kinase in human breast cancer | |
| P478 | volume | 99 |
| Q36037262 | 3D culture of Her2+ breast cancer cells promotes AKT to MAPK switching and a loss of therapeutic response |
| Q47784163 | A Rationale for Targeting Extracellular Regulated Kinases ERK1 and ERK2 in Glioblastoma |
| Q35104763 | A decade of tyrosine kinases: from gene discovery to therapeutics |
| Q48341367 | A lab-on-a-chip for monolith-based preconcentration and electrophoresis separation of phosphopeptides |
| Q54096122 | A lymphoma growth inhibitor blocks some but not all prolactin-stimulated signaling pathways. |
| Q37387466 | A novel variant of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cells |
| Q42029877 | A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase |
| Q38708251 | A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability. |
| Q42798912 | Activation of extracellular signal-regulated kinase 1/2 inhibits type I collagen expression by human skin fibroblasts |
| Q74428408 | Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma |
| Q34132949 | Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization |
| Q40811155 | Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line |
| Q34781601 | Active erk regulates microtubule stability in H-ras-transformed cells |
| Q37399268 | Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity |
| Q33992717 | AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer |
| Q40977946 | Altered Gq/G11 guanine nucleotide regulatory protein expression in a rat model of hepatocellular carcinoma: role in mitogenesis |
| Q39304192 | Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9. |
| Q39418968 | Antimetastatic effects and mechanisms of apo-8'-lycopenal, an enzymatic metabolite of lycopene, against human hepatocarcinoma SK-Hep-1 cells |
| Q34016286 | Apoptosis and melanogenesis in human melanoma cells induced by anthrax lethal factor inactivation of mitogen-activated protein kinase kinase |
| Q33816025 | Associations between clinicopathological prognostic factors and pAkt, pMAPK and topoisomerase II expression in breast cancer |
| Q39780631 | BAG-1 overexpression attenuates luminal apoptosis in MCF-10A mammary epithelial cells through enhanced RAF-1 activation. |
| Q64130726 | Benzo[a]pyrene-induced cell cycle progression is through ERKs/cyclin D1 pathway and requires the activation of JNKs and p38 mapk in human diploid lung fibroblasts |
| Q33652374 | Biochanin A Modulates Cell Viability, Invasion, and Growth Promoting Signaling Pathways in HER-2-Positive Breast Cancer Cells |
| Q28368373 | Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo |
| Q35210178 | Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice |
| Q54068363 | Both FGF1 and bcl-x synthesis are necessary for the reduction of apoptosis in retinal pigmented epithelial cells by FGF2: role of the extracellular signal-regulated kinase 2. |
| Q39263970 | Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail signaling pathway. |
| Q37039023 | CYP1A1 regulates breast cancer proliferation and survival |
| Q39783585 | Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway |
| Q35070726 | Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness |
| Q36079223 | Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention |
| Q41916859 | Central role of protein kinase Cepsilon in constitutive activation of ERK1/2 and Rac1 in the malignant cells of hairy cell leukemia |
| Q37750770 | Clinical overview of sorafenib in breast cancer |
| Q47123785 | Combined targeting of Raf and Mek synergistically inhibits tumorigenesis in triple negative breast cancer model systems |
| Q35303180 | Complex prolactin crosstalk in breast cancer: new therapeutic implications |
| Q59881138 | Constitutive ERK1/2 Activation in Esophagogastric Rib Bone Marrow Micrometastatic Cells Is MEK-independent |
| Q47718793 | Constitutively tyrosine phosphorylated p52 Shc in breast cancer cells: correlation with ErbB2 and p66 Shc expression |
| Q36017569 | Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells |
| Q33470005 | Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells |
| Q33959863 | Differences in integrin expression and signaling within human breast cancer cells |
| Q38273722 | Differential regulation of MAP kinase cascade in human colorectal tumorigenesis |
| Q35757179 | Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity |
| Q34507528 | Distinct gene expression profiles in ovarian cancer linked to Lynch syndrome |
| Q37355092 | Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines |
| Q36626059 | Dual blockade of EGFR and ERK1/2 phosphorylation potentiates growth inhibition of breast cancer cells |
| Q46418277 | ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis |
| Q46592752 | ERK1/2 inhibition increases antiestrogen treatment efficacy by interfering with hypoxia-induced downregulation of ERalpha: a combination therapy potentially targeting hypoxic and dormant tumor cells. |
| Q36694670 | ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours. |
| Q44384358 | ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer |
| Q34064164 | ERK2 enters the nucleus by a carrier-independent mechanism |
| Q37302065 | ERα-XPO1 Cross Talk Controls Tamoxifen Sensitivity in Tumors by Altering ERK5 Cellular Localization. |
| Q36397319 | Effect of phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. |
| Q40741654 | Effect of prolonged hydroxytamoxifen treatment of MCF-7 cells on mitogen activated kinase cascade. |
| Q36430224 | Effects of MAP kinase inhibitors on epidermal growth factor-induced neoplastic transformation of human keratinocytes |
| Q54977616 | Effects of PTEN Loss and Activated KRAS Overexpression on Mechanical Properties of Breast Epithelial Cells. |
| Q43766091 | Effects of marine sponge extracts on mitogen-activated protein kinase (MAPK/ERK(1,2)) activity in SW-13 human adrenal carcinoma cells |
| Q42524158 | Elevated JNK activation contributes to the pathogenesis of human brain tumors |
| Q54953677 | Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer. |
| Q35084786 | Endocrine-responsive breast cancer and strategies for combating resistance |
| Q40977937 | Enhanced Gi-protein-mediated mitogenesis following chronic ethanol exposure in a rat model of experimental hepatocellular carcinoma |
| Q42820312 | Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38. |
| Q34118830 | Epidermal growth factor receptor (EGFR) transactivation by estrogen via the G-protein-coupled receptor, GPR30: a novel signaling pathway with potential significance for breast cancer |
| Q35134513 | Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer |
| Q36326248 | ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases |
| Q40430785 | Essential role of p38gamma in K-Ras transformation independent of phosphorylation |
| Q28245969 | Estrogen receptor alpha in human breast cancer: occurrence and significance |
| Q37092668 | Exposure to estrogen and ionizing radiation causes epigenetic dysregulation, activation of mitogen-activated protein kinase pathways, and genome instability in the mammary gland of ACI rats |
| Q36616070 | Expression and prognostic relevance of activated extracellular-regulated kinases (ERK1/2) in breast cancer |
| Q28580406 | Extracellular signal-regulated kinase 7, a regulator of hormone-dependent estrogen receptor destruction |
| Q37480927 | Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression. |
| Q91675540 | FAM53A Affects Breast Cancer Cell Proliferation, Migration, and Invasion in a p53-Dependent Manner |
| Q35004480 | Farnesyltransferase inhibitors in breast cancer therapy |
| Q33572280 | Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity |
| Q40738340 | Future treatment modalities for meningiomas: targeting of neurofibromatosis type 2 and Ras-regulated pathways. |
| Q34638973 | GADD45α induction by nickel negatively regulates JNKs/p38 activation via promoting PP2Cα expression |
| Q36961082 | Gene-based analysis of the fibroblast growth factor receptor signaling pathway in relation to breast cancer in African American women: the AMBER consortium |
| Q40543091 | Genetic alterations of the NRP/B gene are associated with human brain tumors |
| Q54517252 | Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor). |
| Q37482022 | Genetic variation in the insulin, insulin-like growth factor, growth hormone, and leptin pathways in relation to breast cancer in African-American women: the AMBER consortium |
| Q34484372 | Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs |
| Q33325484 | Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells |
| Q43829384 | Growth and characterization of N-methyl-N-nitrosourea-induced mammary tumors in intact and ovariectomized rats |
| Q33717222 | High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886) |
| Q46770101 | In Silico Drug-Designing Studies on Flavanoids as Anticolon Cancer Agents: Pharmacophore Mapping, Molecular Docking, and Monte Carlo Method-Based QSAR Modeling |
| Q30444938 | In situ visualization of intratumor growth factor signaling: immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms |
| Q73156229 | Increased activity and expression of MAP kinase in HCC model rats induced by 3'-methyl-4-dimethylamino-azobenzene |
| Q41913592 | Increased expression of mitogen-activated protein kinase and its upstream regulating signal in human gastric cancer |
| Q40346066 | Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38. |
| Q39955774 | Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells |
| Q33967999 | Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. |
| Q37213805 | Integrated analysis of breast cancer cell lines reveals unique signaling pathways |
| Q42795900 | Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation |
| Q39752824 | JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70. |
| Q36996036 | Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells |
| Q51265005 | Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers. |
| Q44010956 | MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance. |
| Q35207726 | MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association |
| Q43621540 | MEK (MAPKK) inhibitors. Part 2: structure-activity relationships of 4-anilino-3-cyano-6,7-dialkoxyquinolines |
| Q73093705 | MEK inhibition enhances paclitaxel-induced tumor apoptosis |
| Q77966155 | MEK wars, a new front in the battle against cancer |
| Q40147018 | MEK/ERK-dependent uPAR expression is required for motility via phosphorylation of P70S6K in human hepatocarcinoma cells |
| Q34946215 | MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis |
| Q54338262 | MKK6 is upregulated in human esophageal, stomach, and colon cancers. |
| Q24320171 | MNK1 and MNK2 regulation in HER2-overexpressing breast cancer lines |
| Q47281356 | MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation |
| Q44689165 | Matrix metalloproteinases (MMP), EMMPRIN (extracellular matrix metalloproteinase inducer) and mitogen-activated protein kinases (MAPK): co-expression in metastatic serous ovarian carcinoma |
| Q34586077 | Mediation of estrogen mitogenic effect in human breast cancer MCF-7 cells by PC-cell-derived growth factor (PCDGF/granulin precursor). |
| Q54224159 | Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity. |
| Q84098237 | Metastatic function of BMP-2 in gastric cancer cells: the role of PI3K/AKT, MAPK, the NF-κB pathway, and MMP-9 expression |
| Q33618363 | MicroRNA-382-5p aggravates breast cancer progression by regulating the RERG/Ras/ERK signaling axis. |
| Q81649991 | Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells |
| Q79124323 | Mitogen-activated protein kinases (MAPK) as predictors of clinical outcome in serous ovarian carcinoma in effusions |
| Q36327729 | Mitogenic signal transduction pathways in meningiomas: novel targets for meningioma chemotherapy? |
| Q24801341 | Modulating sensitivity to drug-induced apoptosis: the future for chemotherapy? |
| Q42508624 | Molecular subtyping of mammary-like adenocarcinoma of the vulva shows molecular similarity to breast carcinomas. |
| Q36955081 | Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer |
| Q37286664 | Multiplex Gene Expression Profiling of 16 Target Genes in Neoplastic and Non-Neoplastic Canine Mammary Tissues Using Branched-DNA Assay |
| Q40897148 | Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation. |
| Q91290944 | NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer |
| Q35622050 | New insights into estrogen receptor function in human breast cancer |
| Q36877009 | New prospects for management and treatment of inoperable and recurrent skull base meningiomas |
| Q47891394 | Nitroxides tempol and tempo induce divergent signal transduction pathways in MDA-MB 231 breast cancer cells |
| Q37343475 | Noonan, Costello and cardio-facio-cutaneous syndromes: dysregulation of the Ras-MAPK pathway |
| Q33842800 | Oestrogen and growth factor cross-talk and endocrine insensitivity and acquired resistance in breast cancer |
| Q35230305 | Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway |
| Q42808394 | Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity |
| Q64955344 | Oncogenic Signaling in Tumorigenesis and Applications of siRNA Nanotherapeutics in Breast Cancer. |
| Q40610753 | Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells |
| Q44346549 | Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer |
| Q24322705 | P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase |
| Q22000770 | PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture |
| Q40939473 | Paradoxical activation of Raf by a novel Raf inhibitor |
| Q40601264 | Peroxisome proliferator-activated receptor-gamma activation inhibits tumor progression in non-small-cell lung cancer. |
| Q43635626 | Phosphorylation of ERK1/2 mitogen-activated protein kinase is associated with poor response to anti-hormonal therapy and decreased patient survival in clinical breast cancer |
| Q44064304 | Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera |
| Q33843989 | Phosphorylation of the transcription factor Ets-1 by ERK2: rapid dissociation of ADP and phospho-Ets-1. |
| Q44744096 | Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma |
| Q40706864 | Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2). |
| Q42463310 | Promoter analysis of the human p44 mitogen-activated protein kinase gene (MAPK3): transcriptional repression under nonproliferating conditions |
| Q39412384 | Protein kinase D1 stimulates proliferation and enhances tumorigenesis of MCF-7 human breast cancer cells through a MEK/ERK-dependent signaling pathway |
| Q36068428 | Proteolytic-antiproteolytic balance and its regulation in carcinogenesis. |
| Q40858535 | RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells |
| Q39426062 | RNAi-mediated knockdown of ERK1/2 inhibits cell proliferation and invasion and increases chemosensitivity to cisplatin in human osteosarcoma U2-OS cells in vitro |
| Q38310978 | Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b |
| Q46202262 | Ras activation in human breast cancer |
| Q36639126 | Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells |
| Q36755844 | Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology |
| Q37619838 | Reduced miR-550a-3p leads to breast cancer initiation, growth, and metastasis by increasing levels of ERK1 and 2. |
| Q40828652 | Regulation of heparin-binding EGF-like growth factor expression in Ha-ras transformed human mammary epithelial cells |
| Q35584927 | Regulation of matrix metalloproteinases: an overview |
| Q54032958 | Regulation of proliferation-survival decisions is controlled by FGF1 secretion in retinal pigmented epithelial cells. |
| Q28565817 | Renal expression and activity of the germinal center kinase SK2 |
| Q53423587 | Rho GTPases are over-expressed in human tumors. |
| Q36624071 | Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters |
| Q53336578 | Role of Gab2 in mammary tumorigenesis and metastasis. |
| Q33407429 | Simultaneous inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways augment the sensitivity to actinomycin D in Ewing sarcoma |
| Q33312289 | Small-molecule based delivery systems for alkylating antineoplastic compounds. |
| Q27630416 | Solution structure of ERK2 binding domain of MAPK phosphatase MKP-3: structural insights into MKP-3 activation by ERK2 |
| Q74355558 | Stimulation of the mitogen-activated protein kinase pathway antagonizes TRAIL-induced apoptosis downstream of BID cleavage in human breast cancer MCF-7 cells |
| Q27765381 | Structural basis of inhibitor selectivity in MAP kinases |
| Q53392573 | Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. |
| Q35054868 | Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways |
| Q44485786 | Synthesis and MEK1 inhibitory activities of imido-substituted 2-chloro-1,4-naphthoquinones |
| Q73334770 | Synthesis and structure-activity relationships of 3-cyano-4-(phenoxyanilino)quinolines as MEK (MAPKK) inhibitors |
| Q40512067 | Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839). |
| Q104795161 | Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides |
| Q35968411 | Targeting the mitogen-activated protein kinase cascade to treat cancer |
| Q74237951 | Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion |
| Q47858529 | Terminal differentiation of human breast cancer through PPAR gamma |
| Q50714059 | The 3'-untranslated region of the Ste20-like kinase SLK regulates SLK expression. |
| Q34241295 | The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors |
| Q36061535 | The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling |
| Q39023984 | The Ras/Raf/MEK/ERK signaling pathway and its role in the occurrence and development of HCC. |
| Q37293348 | The RasGAP gene, RASAL2, is a tumor and metastasis suppressor |
| Q36546319 | The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence |
| Q81405014 | The differentiation of benign and malignant thyroid nodules |
| Q39030548 | The effects of p38 gene silencing on breast cancer cells. |
| Q24633325 | The functional contrariety of JNK |
| Q41036869 | The hyaluronan receptor RHAMM regulates extracellular-regulated kinase |
| Q46950108 | The mitogen-activated protein kinase pathway can inhibit TRAIL-induced apoptosis by prohibiting association of truncated Bid with mitochondria |
| Q82633614 | The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma |
| Q33995206 | The potential role of extracellular regulatory kinase in the survival of patients with early stage adenocarcinoma |
| Q34316122 | The ras signaling pathway in mammary tumorigenesis and metastasis. |
| Q34639829 | The role of c-erbB-2/HER2/neu in breast cancer progression and metastasis |
| Q28390036 | The role of cadmium and nickel in estrogen receptor signaling and breast cancer: metalloestrogens or not? |
| Q30308930 | The role of mitogen-activated protein (MAP) kinase in breast cancer |
| Q37468213 | The silent estrogen receptor--can we make it speak? |
| Q24323035 | Thrombin receptor overexpression in malignant and physiological invasion processes |
| Q33969423 | Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294. |
| Q35578521 | Triptolide inhibits human breast cancer MCF-7 cell growth via downregulation of the ERα-mediated signaling pathway |
| Q28368422 | Tumor promoter arsenite activates extracellular signal-regulated kinase through a signaling pathway mediated by epidermal growth factor receptor and Shc. |
| Q37086205 | VEGF promotes gastric cancer development by upregulating CRMP4. |
| Q36791090 | YB-1 is a Transcription/Translation Factor that Orchestrates the Oncogenome by Hardwiring Signal Transduction to Gene Expression |
| Q34519896 | ZD1839 (Iressa), a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, potently inhibits the growth of EGFR-positive cancer cell lines with or without erbB2 overexpression |
| Q33585060 | mRNA expression of DOK1-6 in human breast cancer |
| Q36687990 | p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion |
| Q33563109 | shRNA interference for extracellular signal-regulated kinase 2 can inhibit the growth of esophageal cancer cell line Eca109. |
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