DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes.

scientific article published on 15 September 2009

DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1024655194
P356DOI10.1186/1476-8518-7-4
P932PMC publication ID2754477
P698PubMed publication ID19754943
P5875ResearchGate publication ID26812791

P50authorAlexandrina SartoriQ56945230
Vania BonatoQ73871099
P2093author name stringCélio L Silva
Deison S Lima
Arlete Am Coelho-Castelo
Patrícia Rm Souza
Rubens R Santos
P2860cites workIntramuscular injection of interleukin-10 plasmid DNA prevented autoimmune diabetes in miceQ44540413
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetesQ46512140
Characterization of the memory/activated T cells that mediate the long-lived host response against tuberculosis after bacillus Calmette-Guérin or DNA vaccination.Q52032470
Protection against tuberculosis by a plasmid DNA vaccine.Q53968477
Therapy of tuberculosis in mice by DNA vaccination.Q54085325
Autoimmune diabetes induced by the beta-cell toxin STZ. Immunity to the 60-kDa heat shock protein and to insulin.Q54198243
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.Q55066037
Insulin-mimicking anti-idiotypic antibodies in development of spontaneous autoimmune diabetes in BB/E ratsQ68611947
The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitusQ71420898
Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunityQ73209258
Genetic aspects and microenvironment affect expression of CD18 and VLA-4 in experimental tuberculosisQ74471095
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signalsQ77704341
Immune regulatory effect of pHSP65 DNA therapy in pulmonary tuberculosis: activation of CD8+ cells, interferon-gamma recovery and reduction of lung injuryQ80454652
Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progressionQ80523271
Immunomodulation and protection induced by DNA-hsp65 vaccination in an animal model of arthritisQ81422020
DNA vaccinesQ93896322
Identification and characterization of protective T cells in hsp65 DNA-vaccinated and Mycobacterium tuberculosis-infected mice.Q33748060
Regulatory T cells in autoimmmunity*.Q33904108
Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcriptionQ34201095
Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD MiceQ34276533
NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cellsQ34390898
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contributionQ34504668
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing TregsQ34546789
C-C chemokine-encoding DNA vaccines enhance breakdown of tolerance to their gene products and treat ongoing adjuvant arthritisQ35126948
Heat-shock proteins induce T-cell regulation of chronic inflammationQ36085622
Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetesQ36377373
Intranasal administration of insulin peptide B: 9-23 protects NOD mice from diabetesQ36796917
Recent advances in DNA vaccines for autoimmune diseasesQ37386307
Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.Q37476298
Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.Q37925551
Mouse models of insulin dependent diabetes: low-dose streptozocin-induced diabetes and nonobese diabetic (NOD) mice.Q39482381
Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes MellitusQ39998473
Insulin-dependent diabetes mellitus as an autoimmune diseaseQ40648707
Diagnosis and treatment of pre-insulin dependent diabetesQ40866289
Regulatory Th2-type T cell lines against insulin and GAD peptides derived from orally- and nasally-treated NOD mice suppress diabetesQ40953893
Suppressive immunization with DNA encoding a self-peptide prevents autoimmune disease: modulation of T cell costimulationQ40964815
Diabetogenic T-cell clonesQ41127610
Cytokines induce the development of functionally heterogeneous T helper cell subsetsQ41732572
Vaccination with DNA encoding an immunodominant myelin basic protein peptide targeted to Fc of immunoglobulin G suppresses experimental autoimmune encephalomyelitisQ42063824
Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signalingQ42416289
Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient miceQ44149442
P4510describes a project that usesImageJQ1659584
P921main subjectinsulitisQ922215
P304page(s)4
P577publication date2009-09-15
P1433published inJournal of immune based therapies and vaccinesQ27719416
P1476titleDNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
P478volume7

Reverse relations

cites work (P2860)
Q50980823Attenuation of experimental asthma by mycobacterial protein combined with CpG requires a TLR9-dependent IFN-γ-CCR2 signalling circuit.
Q50974904Bacille Calmette-Guérin/DNAhsp65 prime-boost is protective against diabetes in non-obese diabetic mice but not in the streptozotocin model of type 1 diabetes.
Q38872408Brugia malayi soluble and excretory-secretory proteins attenuate development of streptozotocin-induced type 1 diabetes in mice
Q38096300Challenges in the research and development of new human vaccines.
Q26779956Complexity and Controversies over the Cytokine Profiles of T Helper Cell Subpopulations in Tuberculosis
Q39388911Filarial Abundant Larval Transcript Protein ALT-2: An Immunomodulatory Therapeutic Agent for Type 1 Diabetes.
Q50507569Recombinant DNA immunotherapy ameliorate established airway allergy in a IL-10 dependent pathway.
Q38872412Therapeutic potential of the immunomodulatory proteins Wuchereria bancrofti L2 and Brugia malayi abundant larval transcript 2 against streptozotocin-induced type 1 diabetes in mice.
Q34086118Toxicological effects of nickel chloride on IgA+ B Cells and sIgA, IgA, IgG, IgM in the intestinal mucosal immunity in broilers
Q37683473pVAXhsp65 Vaccination Primes for High IL-10 Production and Decreases Experimental Encephalomyelitis Severity.

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