Combination of nanoindentation and quantitative backscattered electron imaging revealed altered bone material properties associated with femoral neck fragility

scientific article published on 12 September 2009

Combination of nanoindentation and quantitative backscattered electron imaging revealed altered bone material properties associated with femoral neck fragility is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00223-009-9289-8
P932PMC publication ID2759010
P698PubMed publication ID19756347
P5875ResearchGate publication ID26814155

P50authorPeter FratzlQ18412191
Nigel LoveridgeQ55033484
Nadja Fratzl-ZelmanQ61822864
P2093author name stringM Weber
J Reeve
B M Misof
K Klaushofer
P Roschger
A Gourrier
P2860cites workThe mineralization density of iliac crest bone from children with osteogenesis imperfectaQ30635476
A combined atomic force microscopy and nanoindentation technique to investigate the elastic properties of bone structural units.Q33193984
Construction of the femoral neck during growth determines its strength in old age.Q33284564
A new scanning electron microscopy approach to the quantification of bone mineral distribution: backscattered electron image grey-levels correlated to calcium K alpha-line intensitiesQ70877642
The role of collagen in the declining mechanical properties of aging human cortical boneQ77975607
The design of mineralised hard tissues for their mechanical functions.Q33774058
Materials become insensitive to flaws at nanoscale: lessons from natureQ34195073
Periosteal remodeling at the femoral neck in nonhuman primatesQ34543466
Bone fragility and collagen cross-links.Q34586748
Diagnosis of osteoporosis and assessment of fracture riskQ34678969
Mechanisms of osteoporosis therapy: a bone strength perspectiveQ35701996
Femoral neck fragility: genes or environment?Q35991844
Bone architecture and fractureQ36203379
The role of collagen in bone strengthQ36338176
Bone quality--the material and structural basis of bone strength and fragilityQ36488553
Bone strength: current conceptsQ36532574
Structural basis of growth-related gain and age-related loss of bone strengthQ36718805
Bone mineralization density distribution in health and disease.Q37039215
Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic womenQ43705379
Age-related changes in the collagen network and toughness of boneQ44058103
Periosteal bone formation--a neglected determinant of bone strengthQ44524233
The effect of zoledronic acid on the intrinsic material properties of healing bone: an indentation studyQ44803023
Bone mineralization density and femoral neck fragilityQ45082928
BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures.Q46016578
Bone matrix quality and plasma homocysteine levelsQ46148214
Composite bounds on the elastic modulus of bone.Q46276969
The role of mineralization and organic matrix in the microhardness of bone tissue from controls and osteoporotic patients.Q46277120
Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controlsQ46281109
Effects of 3- and 5-year treatment with risedronate on bone mineralization density distribution in triple biopsies of the iliac crest in postmenopausal womenQ46281552
Association of COLIA1 Sp1 alleles with defective bone nodule formation in vitro and abnormal bone mineralization in vivoQ46283733
The mechanical consequences of variation in the mineral content of boneQ46286385
Biomechanical implications of mineral content and microstructural variations in cortical bone of horse, elk, and sheep calcaneiQ46292086
Mineral crystals in calcified tissues: a comparative study by SAXS.Q46297259
Effects of bisphosphonates on matrix mineralizationQ46368102
Femoral neck fragility in women has its structural and biomechanical basis established by periosteal modeling during growth and endocortical remodeling during agingQ47397551
Femoral neck trabecular bone: loss with aging and role in preventing fracture.Q51640359
Intracapsular hip fracture and the region-specific loss of cortical bone: analysis by peripheral quantitative computed tomography.Q52059123
Relation between age, femoral neck cortical stability, and hip fracture risk.Q53851469
Intracapsular hip fracture: increased cortical remodeling in the thinned and porous anterior region of the femoral neck.Q54074832
From brittle to ductile fracture of boneQ63761665
Pamidronate does not adversely affect bone intrinsic material properties in children with osteogenesis imperfectaQ63761677
Nanoscale Deformation Mechanisms in BoneQ63761684
Two different correlations between nanoindentation modulus and mineral content in the bone–cartilage interfaceQ63761697
Scanning Small Angle X-ray Scattering Analysis of Human Bone SectionsQ63761801
Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsiesQ63761811
Post-translational modifications in the collagen of human osteoporotic femoral headQ68200580
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectnanoindentationQ1549892
P304page(s)335-343
P577publication date2009-09-12
P1433published inCalcified Tissue InternationalQ5018771
P1476titleCombination of nanoindentation and quantitative backscattered electron imaging revealed altered bone material properties associated with femoral neck fragility
P478volume85

Reverse relations

cites work (P2860)
Q6405175050 years of scanning electron microscopy of bone—a comprehensive overview of the important discoveries made and insights gained into bone material properties in health, disease, and taphonomy
Q34402472Age-dependence of power spectral density and fractal dimension of bone mineralized matrix in atomic force microscope topography images: potential correlates of bone tissue age and bone fragility in female femoral neck trabeculae.
Q33588406At the moment of occurrence of a fragility hip fracture, men have higher mechanical properties values in comparison with women.
Q44488522Atomic force microscopy characterization of the external cortical bone surface in young and elderly women: potential nanostructural traces of periosteal bone apposition during aging.
Q38066387Bone mineralization: from tissue to crystal in normal and pathological contexts
Q38364893Bone's Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment.
Q35809047Clinical profiles and risk factors for outcomes in older patients with cervical and trochanteric hip fracture: similarities and differences
Q30446436Computational and experimental methodology for site-matched investigations of the influence of mineral mass fraction and collagen orientation on the axial indentation modulus of lamellar bone
Q41299466Distribution of mesoscale elastic properties and mass density in the human femoral shaft
Q55001621Effects of Moisture Content and Loading Profile on Changing Properties of Bone Micro-Biomechanical Characteristics.
Q36449001Fourier transform infrared imaging of femoral neck bone: reduced heterogeneity of mineral-to-matrix and carbonate-to-phosphate and more variable crystallinity in treatment-naive fracture cases compared with fracture-free controls
Q28080834Fragility of Bone Material Controlled by Internal Interfaces
Q84417569Human bone material characterization: integrated imaging surface investigation of male fragility fractures
Q33958167Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior
Q53752406Intrinsic material property differences in bone tissue from patients suffering low-trauma osteoporotic fractures, compared to matched non-fracturing women.
Q35590473Lathyrism-induced alterations in collagen cross-links influence the mechanical properties of bone material without affecting the mineral
Q57901229Mechanical Behavior of Osteoporotic Bone at Sub-Lamellar Length Scales
Q30457555Microfibril orientation dominates the microelastic properties of human bone tissue at the lamellar length scale.
Q46291893Mineralization pattern of vertebral bone material following fragility fracture of the spine
Q52879709Modeling of femoral neck cortical bone for the numerical simulation of ultrasound propagation.
Q49974253Multiscale characterization of cortical bone composition, microstructure, and nanomechanical properties in experimentally induced osteoporosis
Q46291288Nanoindentation measurements of biomechanical properties in mature and newly formed bone tissue surrounding an implant
Q33828962New laboratory tools in the assessment of bone quality
Q88993244On the Relation of Bone Mineral Density and the Elastic Modulus in Healthy and Pathologic Bone
Q37720674Presence of pyrophosphate in bone from an atypical femoral fracture site: A case report.
Q47232182Quantitative ultrasound of cortical bone in the femoral neck predicts femur strength: results of a pilot study
Q33923122Reduced tissue-level stiffness and mineralization in osteoporotic cancellous bone
Q34224609Relating micromechanical properties and mineral densities in severely suppressed bone turnover patients, osteoporotic patients, and normal subjects
Q35731108Relationship of bone mineralization density distribution (BMDD) in cortical and cancellous bone within the iliac crest of healthy premenopausal women.
Q39170719Role of cortical bone in hip fracture
Q46285103Sclerostin deficiency is linked to altered bone composition
Q47272523Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients.
Q37253650Spatial distribution of the trace elements zinc, strontium and lead in human bone tissue
Q39785113Synchrotron radiation micro X-ray fluorescence spectroscopy of thin structures in bone samples: comparison of confocal and color X-ray camera setups
Q30439769The fragile elderly hip: mechanisms associated with age-related loss of strength and toughness
Q38855221Tissue-Level Mechanical Properties of Bone Contributing to Fracture Risk

Search more.