| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1048997066 |
| P356 | DOI | 10.1007/S00223-015-9971-Y |
| P698 | PubMed publication ID | 25712256 |
| P5875 | ResearchGate publication ID | 272841346 |
| P50 | author | Ego Seeman | Q41546810 |
| P2093 | author name string | Y Bala | |
| P2860 | cites work | Characterization of osteoclasts from patients harboring a G215R mutation in ClC-7 causing autosomal dominant osteopetrosis type II | Q24672242 |
| Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling | Q28240767 | ||
| Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength | Q28274891 | ||
| Heterogeneous glycation of cancellous bone and its association with bone quality and fragility | Q28482286 | ||
| The mineralization density of iliac crest bone from children with osteogenesis imperfecta | Q30635476 | ||
| Water-mediated structuring of bone apatite | Q30689261 | ||
| Abnormal mineral composition of osteogenesis imperfecta bone as determined by electron probe X-ray microanalysis on conventional and cryosections | Q30715453 | ||
| Cement lines of secondary osteons in human bone are not mineral-deficient: new data in a historical perspective | Q30794151 | ||
| Microindentation for in vivo measurement of bone tissue mechanical properties in humans. | Q30979077 | ||
| Bisphosphonate treatment modifies canine bone mineral and matrix properties and their heterogeneity. | Q33665130 | ||
| Osteopontin deficiency increases bone fragility but preserves bone mass | Q33872326 | ||
| Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys | Q33874897 | ||
| Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior | Q33958167 | ||
| Age-related changes in the plasticity and toughness of human cortical bone at multiple length scales. | Q34004460 | ||
| Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. | Q34009569 | ||
| Relating micromechanical properties and mineral densities in severely suppressed bone turnover patients, osteoporotic patients, and normal subjects | Q34224609 | ||
| Mean wall thickness of trabecular bone packets in the human iliac crest: changes with age | Q34285855 | ||
| Deuterium nuclear magnetic resonance unambiguously quantifies pore and collagen-bound water in cortical bone | Q34341153 | ||
| Preferred collagen fiber orientation in the human mid-shaft femur. | Q47398741 | ||
| Nanomechanics of collagen fibrils under varying cross-link densities: atomistic and continuum studies | Q48004374 | ||
| The effect of bone microstructure on the initiation and growth of microcracks. | Q50776740 | ||
| Changes in the contents of enzymatic immature, mature, and non-enzymatic senescent cross-links of collagen after once-weekly treatment with human parathyroid hormone (1-34) for 18 months contribute to improvement of bone strength in ovariectomized m | Q51536719 | ||
| Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. | Q51565506 | ||
| Cellular kinetics of the bone remodeling sequence in the rat. | Q51861953 | ||
| The associations between mineral crystallinity and the mechanical properties of human cortical bone. | Q51897048 | ||
| The bone-remodeling transient: implications for the interpretation of clinical studies of bone mass change. | Q52370918 | ||
| Mechanical and mineral properties of osteogenesis imperfecta human bones at the tissue level. | Q53066949 | ||
| Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength. | Q53478410 | ||
| New observations on bone quality in mild primary hyperparathyroidism as determined by quantitative backscattered electron imaging. | Q53501557 | ||
| Infrared imaging of calcified tissue in bone biopsies from adults with osteomalacia. | Q54068398 | ||
| Effect of treatment for 6 months with human parathyroid hormone (1-34) peptide in ovariectomized cynomolgus monkeys (Macaca fascicularis). | Q54078325 | ||
| Bone and Tooth Mineralization: Why Apatite? | Q56976746 | ||
| Osteonal crack barriers in ovine compact bone | Q57880021 | ||
| The effects of ageing and changes in mineral content in degrading the toughness of human femora | Q59295442 | ||
| Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture | Q34434711 | ||
| Dilatational band formation in bone | Q34468075 | ||
| A biomechanical analysis of the effects of resorption cavities on cancellous bone strength | Q34551219 | ||
| Bone mineralization is elevated and less heterogeneous in adults with type 2 diabetes and osteoarthritis compared to controls with osteoarthritis alone | Q34565606 | ||
| Mineral changes in osteoporosis: a review | Q34600560 | ||
| Determinants of microdamage in elderly human vertebral trabecular bone | Q34606313 | ||
| The degree of mineralization of bone tissue measured by computerized quantitative contact microradiography | Q34645375 | ||
| New insights into the effects of primary hyperparathyroidism on the cortical and trabecular compartments of bone | Q35021479 | ||
| Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties | Q35086326 | ||
| Effects of non-enzymatic glycation on cancellous bone fragility. | Q35429093 | ||
| Non-enzymatic glycation alters microdamage formation in human cancellous bone. | Q35429148 | ||
| Bone strength in primary hyperparathyroidism | Q35541117 | ||
| Decreased bone turnover and deterioration of bone structure in two cases of pycnodysostosis | Q35740740 | ||
| Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue. | Q35741491 | ||
| How tough is brittle bone? Investigating osteogenesis imperfecta in mouse bone | Q35771774 | ||
| Association of BMD and FRAX score with risk of fracture in older adults with type 2 diabetes | Q35780843 | ||
| Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta mice. | Q36125953 | ||
| The role of collagen in bone strength | Q36338176 | ||
| Bone quality--the material and structural basis of bone strength and fragility | Q36488553 | ||
| Relations between tensile impact properties and microstructure of compact bone | Q36581938 | ||
| Crosslink in bone collagen in Paget's disease | Q36589280 | ||
| Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes--a meta-analysis | Q36636165 | ||
| Insights into material and structural basis of bone fragility from diseases associated with fractures: how determinants of the biomechanical properties of bone are compromised by disease. | Q36697904 | ||
| Hypophosphatemic rickets is associated with disruption of mineral orientation at the nanoscale in the flat scapula bones of rachitic mice with development | Q36852696 | ||
| Bone quality determined by Fourier transform infrared imaging analysis in mild primary hyperparathyroidism | Q36938387 | ||
| Spectroscopic markers of bone quality in alendronate-treated postmenopausal women | Q37149051 | ||
| Biological co-adaptation of morphological and composition traits contributes to mechanical functionality and skeletal fragility | Q37150659 | ||
| Pentosidine and increased fracture risk in older adults with type 2 diabetes | Q37257534 | ||
| Use of FTIR spectroscopic imaging to identify parameters associated with fragility fracture. | Q37315942 | ||
| Combination of nanoindentation and quantitative backscattered electron imaging revealed altered bone material properties associated with femoral neck fragility | Q37380294 | ||
| The contribution of collagen crosslinks to bone strength | Q37404948 | ||
| Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus | Q37598559 | ||
| In vivo assessment of bone quality in postmenopausal women with type 2 diabetes | Q37652868 | ||
| Bone mineralization: from tissue to crystal in normal and pathological contexts | Q38066387 | ||
| Diabetes, collagen, and bone quality | Q38195566 | ||
| Collagen modifications in postmenopausal osteoporosis: advanced glycation endproducts may affect bone volume, structure and quality | Q38216337 | ||
| During sideways falls proximal femur fractures initiate in the superolateral cortex: evidence from high-speed video of simulated fractures. | Q39971210 | ||
| Bone water | Q41200047 | ||
| Composition of the cement line and its possible mechanical role as a local interface in human compact bone | Q41421023 | ||
| Bone tissue in Paget's disease of bone. Ultrastructure and Immunocytology | Q41614469 | ||
| Changes in the impact energy absorption of bone with age | Q41686776 | ||
| The influence of water removal on the strength and toughness of cortical bone. | Q41760891 | ||
| Fluoride effects on bone formation and mineralization are influenced by genetics | Q41953831 | ||
| Homocysteine suppresses the expression of the collagen cross-linker lysyl oxidase involving IL-6, Fli1, and epigenetic DNA methylation | Q41986504 | ||
| The relative contributions of non-enzymatic glycation and cortical porosity on the fracture toughness of aging bone | Q42161678 | ||
| Collagen packing and mineralization. An x-ray scattering investigation of turkey leg tendon. | Q42584065 | ||
| Evolving data about subtrochanteric fractures and bisphosphonates | Q43119630 | ||
| Effects of long-term alendronate treatment on postmenopausal osteoporosis bone material properties | Q43689965 | ||
| Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women | Q43705379 | ||
| Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density | Q43842242 | ||
| Severe dental fluorosis in a Tanzanian population consuming water with negligible fluoride concentration | Q43952553 | ||
| Changes in bone remodeling rate influence the degree of mineralization of bone | Q44254005 | ||
| Intermittent intravenous administration of the bisphosphonate ibandronate prevents bone loss and maintains bone strength and quality in ovariectomized cynomolgus monkeys | Q44313218 | ||
| Contribution of raloxifene and calcium and vitamin D3 supplementation to the increase of the degree of mineralization of bone in postmenopausal women | Q44582475 | ||
| Calculation of porosity and osteonal cement line effects on the effective fracture toughness of cortical bone in longitudinal crack growth | Q44873441 | ||
| Decreased bone remodeling and porosity are associated with improved bone strength in ovariectomized cynomolgus monkeys treated with denosumab, a fully human RANKL antibody | Q45419865 | ||
| Time sequence of secondary mineralization and microhardness in cortical and cancellous bone from ewes. | Q46273860 | ||
| The degree and distribution of cortical bone mineralization in the human femoral shaft change with age and sex in a microradiographic study | Q46274926 | ||
| The role of mineralization and organic matrix in the microhardness of bone tissue from controls and osteoporotic patients. | Q46277120 | ||
| Collagen maturity, glycation induced-pentosidine, and mineralization are increased following 3-year treatment with incadronate in dogs | Q46277861 | ||
| In situ examination of the time-course for secondary mineralization of Haversian bone using synchrotron Fourier transform infrared microspectroscopy | Q46279213 | ||
| The bone mineralization density distribution as a fingerprint of the mineralization process | Q46280296 | ||
| Degree of mineralization-related collagen crosslinking in the femoral neck cancellous bone in cases of hip fracture and controls | Q46281109 | ||
| Effects of 3- and 5-year treatment with risedronate on bone mineralization density distribution in triple biopsies of the iliac crest in postmenopausal women | Q46281552 | ||
| Reductions in degree of mineralization and enzymatic collagen cross-links and increases in glycation-induced pentosidine in the femoral neck cortex in cases of femoral neck fracture | Q46282165 | ||
| Bone mineral and collagen quality in iliac crest biopsies of patients given teriparatide: new results from the fracture prevention trial | Q46283704 | ||
| Bone quality of the newest bone formed after two years of teriparatide therapy in patients who were previously treatment-naïve or on long-term alendronate therapy | Q46284190 | ||
| Trends in trabecular architecture and bone mineral density distribution in 152 individuals aged 30-90 years. | Q46284757 | ||
| Sclerostin deficiency is linked to altered bone composition | Q46285103 | ||
| The tensile properties of single osteons | Q46287519 | ||
| Symmetrically reduced stiffness and increased extensibility in compression and tension at the mineralized fibrillar level in rachitic bone. | Q46289492 | ||
| Bone micromechanical properties are compromised during long-term alendronate therapy independently of mineralization. | Q46292054 | ||
| Significant deterioration in nanomechanical quality occurs through incomplete extrafibrillar mineralization in rachitic bone: evidence from in-situ synchrotron X-ray scattering and backscattered electron imaging | Q46292105 | ||
| Mechanistic aspects of fracture and R-curve behavior in human cortical bone. | Q46614188 | ||
| Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite | Q46620565 | ||
| Extracellular post-translational modifications of collagen are major determinants of biomechanical properties of fetal bovine cortical bone | Q46791836 | ||
| Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra. | Q46840159 | ||
| Mineral particle size in children with osteogenesis imperfecta type I is not increased independently of specific collagen mutations | Q47196656 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 308-326 | |
| P577 | publication date | 2015-02-25 | |
| P1433 | published in | Calcified Tissue International | Q5018771 |
| P1476 | title | Bone's Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment | |
| P478 | volume | 97 |
| Q95266430 | Altered topological blueprint of trabecular bone associates with skeletal pathology in humans |
| Q91521103 | Antiresorptive and anabolic agents in the prevention and reversal of bone fragility |
| Q37214385 | Assessing the inter- and intra-animal variability of in vivo OsteoProbe skeletal measures in untreated dogs. |
| Q30234636 | Bone Quality in Chronic Kidney Disease: Definitions and Diagnostics. |
| Q51751793 | Bone quality changes associated with aging and disease: a review. |
| Q46987405 | Insights into the bisphosphonate holiday: a preliminary FTIRI study |
| Q40543803 | Irreversible Deterioration of Cortical and Trabecular Microstructure Associated With Breastfeeding |
| Q49974253 | Multiscale characterization of cortical bone composition, microstructure, and nanomechanical properties in experimentally induced osteoporosis |
| Q59126536 | Rethinking Bone Disease in Kidney Disease |
| Q55359589 | Soy protein improves tibial whole-bone and tissue-level biomechanical properties in ovariectomized and ovary-intact, low-fit female rats. |
| Q53699099 | The Role of Matrix Composition in the Mechanical Behavior of Bone. |
| Q46276556 | The incorporation of fluoride and strontium in hydroxyapatite affects the composition, structure, and mechanical properties of human cortical bone |
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