Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring.

scientific article published on May 1998

Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI1567
P932PMC publication ID508805
P698PubMed publication ID9593773
P5875ResearchGate publication ID13689936

P50authorRobert S LindsayQ40664138
P2093author name stringC J Kenyon
J R Seckl
A Burchell
M J Nyirenda
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Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.Q35766616
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Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysisQ35995063
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Adult glucose and lipid metabolism may be programmed during fetal lifeQ40481088
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Impaired suppression of gluconeogenesis induced by overexpression of a noninsulin-responsive phosphoenolpyruvate carboxykinase geneQ41518429
Hepatocyte nuclear factor 1 and the glucocorticoid receptor synergistically activate transcription of the rat insulin-like growth factor binding protein-1 geneQ42447067
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Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis.Q48715758
Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat.Q48845874
Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone.Q51578750
Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice.Q51586289
Factors underlying significant underestimations of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity.Q51630433
Abnormalities in hepatic enzyme activities during development of diabetes in db mice.Q51684165
Cushing's syndrome: diagnostic criteria.Q52131428
Development regulation of basal and hormone-inducible phosphoenolpyruvate carboxykinase gene expression in chick embryo liver in vivo.Q52218316
Neonatal programming of androgen responsiveness of liver of adult rats.Q54036792
Glucocorticoid-Induced Insulin Resistance: Dexamethasone Inhibits the Activation of Glucose Transport in Rat Skeletal Muscle by Both Insulin- and Non-Insulin-Related StimuliQ54176504
Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the ratQ57659942
Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cellsQ59071105
Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?Q59921596
11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta- reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulationsQ61865428
Determination of phosphoenolpyruvate carboxykinase activity with deoxyguanosine 5′-diphosphate as nucleotide substrateQ66919799
Prenatal exposure to prednisone in humans and animals retards intrauterine growthQ67399513
A new microtechnique for the analysis of the human hepatic microsomal glucose-6-phosphatase systemQ69828920
Glucocorticoids regulate the induction of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetesQ72083309
Elevated levels of umbilical cord plasma corticotropin-releasing hormone in growth-retarded fetusesQ72165950
Differences in temperature-sensitive receptor binding of glucocorticoids in spontaneously hypertensive and normotensive Wistar-Kyoto ratsQ72339103
The effects of cortisol on hepatic and renal gluconeogenic enzyme activities in the sheep fetus during late gestationQ72817595
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectglucoseQ37525
glycobiologyQ899224
glucose intoleranceQ2661464
P304page(s)2174-2181
P577publication date1998-05-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleGlucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring
P478volume101

Reverse relations

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