Mechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism

scientific article published in December 1990

Mechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI114940
P932PMC publication ID329842
P698PubMed publication ID2254458
P5875ResearchGate publication ID20900530

P50authorJohn E. GerichQ112187461
P2093author name stringJ J Reilly
D M Bier
A Consoli
N Nurjhan
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Conversion of DL-lactate-2-C14 or -3-C14 or pyruvate-2-C14 to blood glucose in humans: effects of diabetes, insulin, tolbutamide, and glucose loadQ33945033
Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitusQ34541876
Metabolic fate of extracted glucose in normal human myocardiumQ34564456
Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissuesQ34577909
Studies of pancreatic alpha cell function in normal and diabetic subjectsQ35576866
Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in manQ35581333
Skeletal muscle glycolysis, oxidation, and storage of an oral glucose loadQ35588419
The measurement of metabolite exchange across muscle bedsQ39700102
Glucose-Lactate Inter-Relations in ManQ39915500
In-vivo Measurement of Glucose and Alanine Metabolism with Stable Isotopic TracersQ40819450
Contribution of impaired muscle glucose clearance to reduced postabsorptive systemic glucose clearance in NIDDM.Q41208158
Determination of stable isotopic enrichment in individual plasma amino acids by chemical ionization mass spectrometryQ41436732
Sample site selection for tracer studies applying a unidirectional circulatory approachQ41879509
Effects of streptozocin-induced diabetes on glucose metabolism and lactate release by isolated fat cells from young lean and older, moderately obese ratsQ42505096
Insulin inhibition of overnight glucose production and gluconeogenesis from lactate in NIDDM.Q43562862
Increased Rate of Cori Cycle in Obese Subjects With NIDDM and Effect of Weight ReductionQ47183976
Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM.Q51621177
Quantification of the relative impairment in actions of insulin on hepatic glucose production and peripheral glucose uptake in non-insulin-dependent diabetes mellitus.Q51627070
Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes.Q51628168
Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus.Q51649670
The disposal of an intravenously administered amino acid load across the human forearm.Q51651060
The effect of chronic sulfonylurea therapy on hepatic glucose production in non-insulin-dependent diabetes.Q51651477
Circulating Alanine Disposal in Diabetes MellitusQ51665139
Measurement of leucine metabolism in man from a primed, continuous infusion of L-[1-3C]leucine.Q52762397
Glutamine and Glutamate Metabolism in Normal and Diabetic SubjectsQ53855118
Glucose uptake in human adipose tissueQ68206142
Evaluation of the isotopic equilibration between lactate and pyruvateQ68304736
Increased resting metabolic rates in obese subjects with non-insulin-dependent diabetes mellitus and the effect of sulfonylurea therapyQ69990093
Measurement of L-[1-14C]leucine kinetics in splanchnic and leg tissues in humans. Effect of amino acid infusionQ70210986
Physiological hypercortisolemia increases proteolysis, glutamine, and alanine productionQ70212857
Lactate extraction during net lactate release in legs of humans during exerciseQ70284388
Muscle mass: reliable indicator of protein-energy malnutrition severity and outcomeQ71604077
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectgluconeogenesisQ191835
L-alanineQ218642
P304page(s)2038-2045
P577publication date1990-12-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism
P478volume86

Reverse relations

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