Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells

scientific article published on 11 August 2009

Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1535-7163.MCT-09-0051
P932PMC publication ID2762647
P698PubMed publication ID19671752
P5875ResearchGate publication ID26733260

P50authorMelissa J. MooreQ85954688
P2093author name stringPaula J Grabowski
Billy W Day
Andreas Vogt
Brian J Albert
Kazunori Koide
Kristine O'Brien
Miaosheng Li
Nancy L Czaicki
Peter A McPherson
Sami Osman
Vincent Destefino
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Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factorsQ36233711
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The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicingQ39934103
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Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.Q40104313
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Liriodenine inhibits the proliferation of human hepatoma cell lines by blocking cell cycle progression and nitric oxide-mediated activation of p53 expressionQ40434571
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Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activitiesQ40554037
Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.Q40766489
A new functional role for P-glycoprotein: efflux pump for benzo(alpha)pyrene in human breast cancer MCF-7 cellsQ41090899
The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactionsQ42501935
Characterization of a new human diploid cell strain, IMR-90.Q42802708
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High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazoleQ44502481
Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis.Q44564121
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Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probesQ45122363
Total synthesis of FR901464, an antitumor agent that regulates the transcription of oncogenes and tumor suppressor genesQ46967605
How rapidly do epoxides nonspecifically form covalent bonds with thiols in water?Q46973459
The use of cell fusion in the analysis of gene action.Q54361169
Amplification and expression of genes associated with multidrug resistance in mammalian cells.Q54428089
DNA damage, cytotoxicity and free radical formation by mitomycin C in human cellsQ64390214
New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of actionQ73070075
On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) aza-dEpoB: a Mitsunobu inversion at C15 in pre-epothilone fragmentsQ73860256
FR901464: total synthesis, proof of structure, and evaluation of synthetic analoguesQ74603704
Total synthesis of the potent antitumor macrolides pladienolide B and DQ80165304
Synthesis of a C4-epi-C1-C6 fragment of FR901464 using a novel bromolactolizationQ80831613
P433issue8
P921main subjectmultiple drug resistanceQ643839
P304page(s)2308-2318
P577publication date2009-08-11
P1433published inMolecular Cancer TherapeuticsQ2363144
P1476titleMeayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells
P478volume8

Reverse relations

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