scholarly article | Q13442814 |
P50 | author | Melissa J. Moore | Q85954688 |
P2093 | author name string | Paula J Grabowski | |
Billy W Day | |||
Andreas Vogt | |||
Brian J Albert | |||
Kazunori Koide | |||
Kristine O'Brien | |||
Miaosheng Li | |||
Nancy L Czaicki | |||
Peter A McPherson | |||
Sami Osman | |||
Vincent Destefino | |||
P2860 | cites work | Protein modularity of alternatively spliced exons is associated with tissue-specific regulation of alternative splicing | Q24812842 |
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei | Q27860728 | ||
Exon silencing by UAGG motifs in response to neuronal excitation | Q28469128 | ||
Requirement for p53 and p21 to sustain G2 arrest after DNA damage | Q29547667 | ||
Targeting multidrug resistance in cancer | Q29616803 | ||
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes | Q29618293 | ||
Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product | Q33234444 | ||
Better conditions for mammalian in vitro splicing provided by acetate and glutamate as potassium counterions | Q33613199 | ||
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors | Q34419716 | ||
P53 mRNA controls p53 activity by managing Mdm2 functions | Q34927261 | ||
Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors | Q36233711 | ||
DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas | Q36352667 | ||
Splicing regulation in neurologic disease | Q36610357 | ||
Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue | Q36864845 | ||
Neuronal regulation of alternative pre-mRNA splicing | Q36951678 | ||
Disparate proteome reactivity profiles of carbon electrophiles | Q39599022 | ||
The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing | Q39934103 | ||
Antitumor compounds based on a natural product consensus pharmacophore | Q39940545 | ||
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. | Q40104313 | ||
SAP155 Binds to ceramide-responsive RNA cis-element 1 and regulates the alternative 5' splice site selection of Bcl-x pre-mRNA. | Q40264404 | ||
Liriodenine inhibits the proliferation of human hepatoma cell lines by blocking cell cycle progression and nitric oxide-mediated activation of p53 expression | Q40434571 | ||
A scalable high-content cytotoxicity assay insensitive to changes in mitochondrial metabolic activity | Q40543612 | ||
Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities | Q40554037 | ||
Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis. | Q40766489 | ||
A new functional role for P-glycoprotein: efflux pump for benzo(alpha)pyrene in human breast cancer MCF-7 cells | Q41090899 | ||
The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions | Q42501935 | ||
Characterization of a new human diploid cell strain, IMR-90. | Q42802708 | ||
The emerging role of splicing factors in cancer | Q43244074 | ||
High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole | Q44502481 | ||
Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis. | Q44564121 | ||
New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities | Q44729411 | ||
Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes | Q45122363 | ||
Total synthesis of FR901464, an antitumor agent that regulates the transcription of oncogenes and tumor suppressor genes | Q46967605 | ||
How rapidly do epoxides nonspecifically form covalent bonds with thiols in water? | Q46973459 | ||
The use of cell fusion in the analysis of gene action. | Q54361169 | ||
Amplification and expression of genes associated with multidrug resistance in mammalian cells. | Q54428089 | ||
DNA damage, cytotoxicity and free radical formation by mitomycin C in human cells | Q64390214 | ||
New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action | Q73070075 | ||
On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) aza-dEpoB: a Mitsunobu inversion at C15 in pre-epothilone fragments | Q73860256 | ||
FR901464: total synthesis, proof of structure, and evaluation of synthetic analogues | Q74603704 | ||
Total synthesis of the potent antitumor macrolides pladienolide B and D | Q80165304 | ||
Synthesis of a C4-epi-C1-C6 fragment of FR901464 using a novel bromolactolization | Q80831613 | ||
P433 | issue | 8 | |
P921 | main subject | multiple drug resistance | Q643839 |
P304 | page(s) | 2308-2318 | |
P577 | publication date | 2009-08-11 | |
P1433 | published in | Molecular Cancer Therapeutics | Q2363144 |
P1476 | title | Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells | |
P478 | volume | 8 |
Q46298922 | A Challenging Pie to Splice: Drugging the Spliceosome. |
Q100513059 | A Comprehensive Overview of Structure-Activity Relationships of Small-Molecule Splicing Modulators Targeting SF3B1 as Anticancer Agents |
Q35826664 | A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis |
Q50033988 | Alternative Splicing as a Target for Cancer Treatment. |
Q26852848 | Alternative splicing for diseases, cancers, drugs, and databases |
Q38735423 | Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems |
Q38060535 | Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms |
Q38675125 | Biosynthesis of polyketides by trans-AT polyketide synthases |
Q37511674 | Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs |
Q35891380 | Computational discovery of pathway-level genetic vulnerabilities in non-small-cell lung cancer |
Q26823040 | Defects in spliceosomal machinery: a new pathway of leukaemogenesis |
Q38712211 | Discoveries, target identifications, and biological applications of natural products that inhibit splicing factor 3B subunit 1. |
Q38017093 | Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders |
Q46189717 | Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer. |
Q34098699 | Garbled messages and corrupted translations |
Q36966213 | Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43 |
Q90598040 | Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation |
Q38583533 | Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing |
Q35301222 | Identification of small molecule inhibitors of pre-mRNA splicing |
Q30775411 | Influenza Virus mRNA Trafficking Through Host Nuclear Speckles. |
Q33567881 | Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus |
Q35619558 | Inhibition of vemurafenib-resistant melanoma by interference with pre-mRNA splicing |
Q36566585 | Interchangeable SF3B1 inhibitors interfere with pre-mRNA splicing at multiple stages |
Q93229701 | MBNL1 alternative splicing isoforms play opposing roles in cancer |
Q26738664 | Modulating splicing with small molecular inhibitors of the spliceosome |
Q33739302 | Multivalent peptidic linker enables identification of preferred sites of conjugation for a potent thialanstatin antibody drug conjugate |
Q38286217 | Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance |
Q38028093 | Pre-mRNA splicing in disease and therapeutics |
Q34551455 | Pre-mRNA splicing is a determinant of nucleosome organization |
Q36873605 | Regulation of primary response genes in B cells |
Q90429889 | Role of Alternative Splicing in Prostate Cancer Aggressiveness and Drug Resistance in African Americans |
Q36485554 | Ruthenium-Catalyzed Olefin Metathesis after Tetra-n-butylammonium Fluoride-Mediated Desilylation |
Q36333518 | SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes |
Q42915987 | Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide |
Q36447664 | Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy |
Q34246700 | Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation |
Q39500409 | Splicing enhances recruitment of methyltransferase HYPB/Setd2 and methylation of histone H3 Lys36. |
Q38187632 | Splicing factor mutations and cancer |
Q61803522 | Splicing modulator FR901464 is a potential agent for colorectal cancer in combination therapy |
Q36485574 | Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464. |
Q39587350 | Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing |
Q36780738 | Targeting RNA splicing for disease therapy |
Q34047259 | Targeting Splicing in the Treatment of Myelodysplastic Syndromes and Other Myeloid Neoplasms. |
Q38826234 | The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1. |
Q34206752 | The Use of 3,5,4'-Tri-O-acetylresveratrol as a Potential Pro-drug for Resveratrol Protects Mice from γ-Irradiation-Induced Death |
Q38033985 | The development and application of small molecule modulators of SF3b as therapeutic agents for cancer. |
Q21090175 | The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing |
Q38057608 | The spliceosome as a target of novel antitumour drugs |
Q42775893 | Total RNA-seq to identify pharmacological effects on specific stages of mRNA synthesis |
Q26864185 | smFRET studies of the 'encounter' complexes and subsequent intermediate states that regulate the selectivity of ligand binding |
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