| scholarly article | Q13442814 |
| P50 | author | Angus Lamond | Q21165211 |
| David W. Gray | Q55175940 | ||
| P2093 | author name string | Ursula Ryder | |
| Reinhard Lührmann | |||
| Timur Samatov | |||
| Stuart McElroy | |||
| Andrea Pawellek | |||
| Andrew Woodland | |||
| Lee Mitchell | |||
| P2860 | cites work | Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes | Q24596441 |
| The spliceosome: design principles of a dynamic RNP machine | Q28131809 | ||
| Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities | Q40554037 | ||
| Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A | Q42146150 | ||
| Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis | Q42412081 | ||
| Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506. | Q43739453 | ||
| A pragmatic approach to the analysis of DNA histograms with a definable G1 peak | Q44745760 | ||
| Single base-pair substitutions in exon-intron junctions of human genes: nature, distribution, and consequences for mRNA splicing | Q48084485 | ||
| Isolation of an active step I spliceosome and composition of its RNP core | Q50336090 | ||
| Splicing factor SF3b as a target of the antitumor natural product pladienolide | Q50672786 | ||
| Identification of SAP155 as the Target of GEX1A (Herboxidiene), an Antitumor Natural Product | Q57228552 | ||
| Splicing-dependent and -independent modes of assembly for intron-encoded box C/D snoRNPs in mammalian cells | Q73727076 | ||
| Isoginkgetin inhibits tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression | Q79377409 | ||
| Pladienolides, new substances from culture of Streptomyces platensis Mer-11107. II. Physico-chemical properties and structure elucidation | Q80109396 | ||
| Manipulation of alternative splicing by a newly developed inhibitor of Clks | Q28249376 | ||
| Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged | Q28297381 | ||
| Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing | Q29547470 | ||
| Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes | Q29618293 | ||
| Lessons learnt from assembling screening libraries for drug discovery for neglected diseases | Q33309109 | ||
| Searching for a wrench to throw into the splicing machine | Q33310593 | ||
| A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators | Q33357493 | ||
| Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay | Q34159087 | ||
| siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells | Q34227843 | ||
| Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation | Q34246700 | ||
| Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein | Q34285180 | ||
| A high-throughput splicing assay identifies new classes of inhibitors of human and yeast spliceosomes | Q34774635 | ||
| A stereoselective synthesis of (+)-herboxidiene/GEX1A. | Q34787886 | ||
| Stalling of spliceosome assembly at distinct stages by small-molecule inhibitors of protein acetylation and deacetylation | Q34887390 | ||
| RNA interference knockdown of hU2AF35 impairs cell cycle progression and modulates alternative splicing of Cdc25 transcripts | Q35128178 | ||
| Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy | Q35221624 | ||
| A Quantitative High-Throughput In Vitro Splicing Assay Identifies Inhibitors of Spliceosome Catalysis | Q35826664 | ||
| The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B | Q35907914 | ||
| The spliceosome: a novel multi-faceted target for therapy | Q36189908 | ||
| Alternative splicing: a new drug target of the post-genome era. | Q36301914 | ||
| Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles | Q36783515 | ||
| Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis | Q36964344 | ||
| Test-firing ammunition for spliceosome inhibition in cancer | Q37339144 | ||
| Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells | Q37388994 | ||
| Golgi Bypass: Skirting Around the Heart of Classical Secretion | Q37858330 | ||
| Alternative splicing in human tumour viruses: a therapeutic target? | Q38022066 | ||
| Cajal bodies: where form meets function | Q38050096 | ||
| The spliceosome as a target of novel antitumour drugs | Q38057608 | ||
| Biological validation that SF3b is a target of the antitumor macrolide pladienolide | Q39461667 | ||
| Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing | Q39587350 | ||
| Rapid-response splicing reporter screens identify differential regulators of constitutive and alternative splicing. | Q39608589 | ||
| Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation | Q39705452 | ||
| UV-induced fragmentation of Cajal bodies. | Q39745903 | ||
| The biflavonoid isoginkgetin is a general inhibitor of Pre-mRNA splicing | Q39934103 | ||
| Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. | Q40104313 | ||
| A sequence motif in the simian virus 40 (SV40) early core promoter affects alternative splicing of transcribed mRNA. | Q40164682 | ||
| Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing | Q40534782 | ||
| P433 | issue | 50 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 16 | |
| P304 | page(s) | 34683-34698 | |
| P577 | publication date | 2014-10-03 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Identification of small molecule inhibitors of pre-mRNA splicing. | |
| P478 | volume | 289 |
| Q46298922 | A Challenging Pie to Splice: Drugging the Spliceosome. |
| Q51220040 | A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore |
| Q36076436 | ATPγS stalls splicing after B complex formation but prior to spliceosome activation |
| Q50033988 | Alternative Splicing as a Target for Cancer Treatment. |
| Q38735423 | Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems |
| Q57753844 | DHX15 regulates CMTR1-dependent gene expression and cell proliferation |
| Q38712211 | Discoveries, target identifications, and biological applications of natural products that inhibit splicing factor 3B subunit 1. |
| Q55437377 | Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling. |
| Q52659676 | Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA splicing factors during adipogenesis. |
| Q92081372 | Emerging Therapeutic Opportunities Based on Current Knowledge of Uveal Melanoma Biology |
| Q48235204 | Flow cytometric analysis identifies changes in S and M phases as novel cell cycle alterations induced by the splicing inhibitor isoginkgetin. |
| Q93337951 | Function, clinical application, and strategies of Pre-mRNA splicing in cancer |
| Q36114523 | Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma |
| Q40506281 | Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana). |
| Q30360791 | Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation. |
| Q28396973 | Identification of hub genes of pneumocyte senescence induced by thoracic irradiation using weighted gene co‑expression network analysis |
| Q26738664 | Modulating splicing with small molecular inhibitors of the spliceosome |
| Q40611609 | Mutagenesis of ARS2 Domains To Assess Possible Roles in Cell Cycle Progression and MicroRNA and Replication-Dependent Histone mRNA Biogenesis |
| Q35558057 | Novel and emerging targeted-based cancer therapy agents and methods |
| Q36447664 | Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy |
| Q49389328 | Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy |
| Q34047259 | Targeting Splicing in the Treatment of Myelodysplastic Syndromes and Other Myeloid Neoplasms. |
| Q55137359 | Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity. |
| Q35789105 | The Natural Product N-Palmitoyl-l-leucine Selectively Inhibits Late Assembly of Human Spliceosomes |
| Q42775893 | Total RNA-seq to identify pharmacological effects on specific stages of mRNA synthesis |
| Q36368952 | Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas |
Search more.