Radiation-induced reductions in neurogenesis are ameliorated in mice deficient in CuZnSOD or MnSOD.

scientific article published on 22 August 2009

Radiation-induced reductions in neurogenesis are ameliorated in mice deficient in CuZnSOD or MnSOD. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.FREERADBIOMED.2009.08.016
P932PMC publication ID2767469
P698PubMed publication ID19703553
P5875ResearchGate publication ID26763721

P50authorMarta Andres-MachQ41138802
Radoslaw RolaQ59221030
P2093author name stringTatiana Suarez
John R Fike
Ting-Ting Huang
Kathleen R Lamborn
Charles L Limoli
Yani Zou
Jennifer Baure
Kelly Fishman
Munjal Acharya
P2860cites workFree radicals and antioxidants in normal physiological functions and human diseaseQ21710698
Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase.Q24671735
Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalanceQ24813418
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate agingQ28191739
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseasesQ28269333
Brain inflammation and adult neurogenesis: the dual role of microgliaQ28288892
Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophyQ28508937
VEGF links hippocampal activity with neurogenesis, learning and memoryQ28578381
Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouseQ28585450
Running enhances neurogenesis, learning, and long-term potentiation in miceQ29391363
Mammalian neural stem cellsQ29547657
Thiol chemistry and specificity in redox signalingQ29615000
Inflammatory Blockade Restores Adult Hippocampal NeurogenesisQ29619037
Replacement of media in cell culture alters oxygen toxicity: possible role of lipid aldehydes and glutathione transferase in oxygen toxicityQ30451433
Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrusQ30479359
Review of oxidative stress in brain and spinal cord injury: suggestions for pharmacological and nutritional management strategiesQ33545928
The use of transgenic and mutant mice to study oxygen free radical metabolismQ33836208
The radioresponse of the central nervous system: a dynamic processQ33900796
Environmental enrichment enhances neurogenesis and improves functional outcome after cranial irradiationQ34002090
Irradiation induces neural precursor-cell dysfunctionQ34142734
Radiation injury and neurogenesisQ34184545
Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat.Q34206312
Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.Q34215922
The glial identity of neural stem cellsQ34272912
Radiation response of neural precursor cells: linking cellular sensitivity to cell cycle checkpoints, apoptosis and oxidative stressQ34284372
Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesisQ34329749
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in lifeQ34366017
High-LET radiation induces inflammation and persistent changes in markers of hippocampal neurogenesisQ34454332
A new mouse model for temporal- and tissue-specific control of extracellular superoxide dismutaseQ34477148
Why new neurons? Possible functions for adult hippocampal neurogenesis.Q34515994
Regulation of neuronal proliferation and differentiation by nitric oxideQ35141387
New roles for astrocytes: redefining the functional architecture of the brainQ35548558
On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studiesQ35548964
Lack of extracellular superoxide dismutase (EC-SOD) in the microenvironment impacts radiation-induced changes in neurogenesisQ35915960
Reactive oxygen species and synaptic plasticity in the aging hippocampusQ35947873
The role of reactive free radicals in ischemic preconditioning--clinical and evolutionary implications.Q36204139
Redox regulation of precursor cell function: insights and paradoxesQ36342622
Adaptive mechanisms to oxidative stress during agingQ36404562
Role and relevance of neurocognitive assessment in clinical trials of patients with CNS tumorsQ36416761
Sources and targets of reactive oxygen species in synaptic plasticity and memoryQ36529803
Managing the cognitive effects of brain tumor radiation therapyQ36619790
Radiation response of neural precursor cells.Q36716071
Cellular niches for endogenous neural stem cells in the adult brainQ37017943
Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and agingQ37090048
The dual functions of thiol-based peroxidases in H2O2 scavenging and signalingQ37170915
Neural precursor cells and central nervous system radiation sensitivityQ37195860
Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disordersQ37254517
Redox state is a central modulator of the balance between self-renewal and differentiation in a dividing glial precursor cellQ37397172
Cell-density-dependent regulation of neural precursor cell function.Q37619408
Age-related losses of cognitive function and motor skills in mice are associated with oxidative protein damage in the brainQ38793015
Fractionated X-radiation treatment can elicit an inducible-like radioprotective response that is not dependent on the intrinsic cellular X-radiation resistance/sensitivityQ40226471
Therapeutic irradiation and brain injuryQ40298944
Neuropsychological effects of cranial radiation: current knowledge and future directionsQ40596222
Free radicals in biology: oxidative stress and the effects of ionizing radiationQ40620886
Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathyQ40720858
Cranial irradiation alters the behaviorally induced immediate-early gene arc (activity-regulated cytoskeleton-associated protein)Q41138748
Pathogenesis of irradiation-induced cognitive dysfunctionQ41236059
Hydrogen peroxide or heat shock induces resistance to hydrogen peroxide in Chinese hamster fibroblastsQ41458386
Cell differentation, aging and cancer: The possible roles of superoxide and superoxide dismutasesQ41549359
Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system.Q41554782
Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiationQ42639860
Differential sensitivity of murine astrocytes and neurons from different brain regions to injuryQ43612001
Neuroprotective effect of eicosapentaenoic acid in hippocampus of rats exposed to gamma-irradiationQ43931409
Transgenic and mutant mice for oxygen free radical studiesQ44041075
Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice.Q44399500
Irradiation attenuates neurogenesis and exacerbates ischemia-induced deficitsQ44781224
A role for adult neurogenesis in spatial long-term memory.Q45226040
Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats.Q45310403
Protective effects of melatonin against ethanol-induced reactive gliosis in hippocampus and cortex of young and aged ratsQ46495133
Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ionsQ46842814
Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus.Q46881337
Oxidative stress in brain ischemia.Q48283261
Demyelination: the role of reactive oxygen and nitrogen speciesQ48283279
Molecular manipulations of extracellular superoxide dismutase: functional importance for learningQ48296270
Sex- and APOE isoform-dependent effects of radiation on cognitive function.Q48346300
Spatial learning and memory deficits after whole-brain irradiation are associated with changes in NMDA receptor subunits in the hippocampus.Q48346310
Integration of new neurons into functional neural networks.Q48361346
Aged SOD overexpressing mice exhibit enhanced spatial memory while lacking hippocampal neurogenesisQ48364211
Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.Q48691176
Adverse long-term effects of brain radiotherapy in adult low-grade glioma patientsQ48868837
Inhibition of neurogenesis interferes with hippocampus-dependent memory function.Q50948959
Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies.Q54299544
Dual role of nitric oxide in adult neurogenesisQ60589501
Glial cell type-specific responses to menadione-induced oxidative stressQ73978549
Estimation of nuclear population from microtome sectionsQ82126847
P433issue10
P921main subjectneurogenesisQ1456827
P304page(s)1459-1467
P577publication date2009-08-22
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleRadiation-induced reductions in neurogenesis are ameliorated in mice deficient in CuZnSOD or MnSOD.
P478volume47

Reverse relations

cites work (P2860)
Q34852226Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.
Q36074438Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53
Q37133488Characterizing low dose and dose rate effects in rodent and human neural stem cells exposed to proton and gamma irradiation
Q44478692Consequences of ionizing radiation-induced damage in human neural stem cells
Q33705495Defining functional changes in the brain caused by targeted stereotaxic radiosurgery
Q48891839Effects of Cu,Zn-superoxide dismutase on cell proliferation and neuroblast differentiation in the mouse dentate gyrus
Q37606455Functional consequences of radiation-induced oxidative stress in cultured neural stem cells and the brain exposed to charged particle irradiation
Q36453492Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction
Q35123948Impairment of adult hippocampal neural progenitor proliferation by methamphetamine: role for nitrotyrosination.
Q64229215Intermittent fasting increases the expressions of SODs and catalase in granule and polymorphic cells and enhances neuroblast dendrite complexity and maturation in the adult gerbil dentate gyrus
Q39434278Jeju ground water containing vanadium enhances antioxidant systems in human liver cells
Q36545682Lithium increases proliferation of hippocampal neural stem/progenitor cells and rescues irradiation-induced cell cycle arrest in vitro.
Q64259148Loss of C/EBPδ Exacerbates Radiation-Induced Cognitive Decline in Aged Mice due to Impaired Oxidative Stress Response
Q93337870Mitochondria as central regulators of neural stem cell fate and cognitive function
Q37768190Modifying radiation damage
Q38534833Oxidative Stress and Adult Neurogenesis
Q26825832Oxidative stress and adult neurogenesis--effects of radiation and superoxide dismutase deficiency
Q35685206Oxidative stress and redox regulation on hippocampal-dependent cognitive functions
Q31123395PROBING THE IMPACT OF GAMMA-IRRADIATION ON THE METABOLIC STATE OF NEURAL STEM AND PRECURSOR CELLS USING DUAL-WAVELENGTH INTRINSIC SIGNAL TWO-PHOTON EXCITED FLUORESCENCE.
Q28392715Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications
Q34474463Paradoxical relationship between Mn superoxide dismutase deficiency and radiation-induced cognitive defects
Q42722452Prenatal carbofuran exposure inhibits hippocampal neurogenesis and causes learning and memory deficits in offspring
Q37982394Redox balance- and radiation-mediated alteration in hippocampal neurogenesis
Q37617667Redox-modulated phenomena and radiation therapy: the central role of superoxide dismutases
Q38937611Relationship between irradiation-induced neuro-inflammatory environments and impaired cognitive function in the developing brain of mice
Q44253783Repeated administration of PEP-1-Cu,Zn-superoxide dismutase and PEP-1-peroxiredoxin-2 to senescent mice induced by D-galactose improves the hippocampal functions
Q47987524Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation.
Q45066738Role of NADPH oxidase in radiation-induced pro-oxidative and pro-inflammatory pathways in mouse brain.
Q34729943Targeted overexpression of mitochondrial catalase prevents radiation-induced cognitive dysfunction
Q26740230The impact of high and low dose ionising radiation on the central nervous system
Q34141823Whole brain radiation-induced impairments in learning and memory are time-sensitive and reversible by systemic hypoxia
Q38150963Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications

Search more.