| scholarly article | Q13442814 |
| P356 | DOI | 10.1128/JVI.78.9.4498-4507.2004 |
| P8608 | Fatcat ID | release_2zp3xxg4hbadpak4fqmobsesry |
| P932 | PMC publication ID | 387686 |
| P698 | PubMed publication ID | 15078930 |
| P2093 | author name string | Andrew D Yurochko | |
| Ian B DeMeritt | |||
| Liesl E Milford | |||
| P2860 | cites work | Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris | Q77386469 |
| Transcriptional coordination of the genes encoding catalytic (CK2alpha) and regulatory (CK2beta) subunits of human protein kinase CK2 | Q77593716 | ||
| Viral threat to newborns under radar | Q77713143 | ||
| The NF-kappa B and I kappa B proteins: new discoveries and insights | Q24313579 | ||
| IKAP is a scaffold protein of the IkappaB kinase complex | Q24316436 | ||
| IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex | Q24316469 | ||
| Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation | Q24316905 | ||
| IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation | Q24321727 | ||
| A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB | Q24321775 | ||
| IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK | Q24321797 | ||
| A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO) | Q24538937 | ||
| IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity | Q24554217 | ||
| Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli | Q24568220 | ||
| Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B | Q24648375 | ||
| Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation | Q24650561 | ||
| Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity | Q27860643 | ||
| Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation | Q28140878 | ||
| The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation | Q28252726 | ||
| Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate | Q28280916 | ||
| NF-kappaB: pivotal mediator or innocent bystander in atherogenesis? | Q28346544 | ||
| Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradation | Q28571179 | ||
| Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway | Q28615706 | ||
| Inflammation in atherosclerosis | Q29547428 | ||
| TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB | Q29614706 | ||
| Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation | Q29614709 | ||
| The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta | Q29617188 | ||
| The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B | Q29618194 | ||
| TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B-like enhancer binding activity which displaces constitutive factors | Q33609443 | ||
| Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex | Q33663188 | ||
| Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant | Q33782001 | ||
| Replication of wild-type and mutant human cytomegalovirus in life-extended human diploid fibroblasts | Q33787378 | ||
| The human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression | Q33797024 | ||
| Control of apoptosis by Rel/NF-kappaB transcription factors | Q33797163 | ||
| Proinflammatory potential of cytomegalovirus infection. specific inhibition of cytomegalovirus immediate-early expression in combination with antioxidants as a novel treatment strategy? | Q33854376 | ||
| Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway | Q33957986 | ||
| Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions | Q33961826 | ||
| Constitutive phosphorylation of I kappa B alpha by casein kinase II | Q33994452 | ||
| NF-kappaB signaling and human disease | Q34264609 | ||
| Nuclear factor kappa-B and the heart | Q34333586 | ||
| Do pathogens accelerate atherosclerosis? | Q34389205 | ||
| NF-kappa B: a crucial transcription factor for glial and neuronal cell function | Q34428983 | ||
| The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection | Q34743775 | ||
| An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis | Q34755471 | ||
| Involvement of NF-kappaB signalling in skin physiology and disease. | Q34980890 | ||
| Absence of IE1 p72 protein function during low-multiplicity infection by human cytomegalovirus results in a broad block to viral delayed-early gene expression | Q34998851 | ||
| NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection | Q35149538 | ||
| High prevalence of latently present cytomegalovirus in arterial walls of patients suffering from grade III atherosclerosis | Q35811381 | ||
| Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters | Q35845633 | ||
| The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection | Q35887796 | ||
| Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. | Q35913517 | ||
| Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infection | Q36090467 | ||
| Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells | Q36161015 | ||
| Promoter-regulatory region of the major immediate early gene of human cytomegalovirus | Q36252923 | ||
| Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B. | Q36295396 | ||
| Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability | Q36557754 | ||
| Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha | Q36560731 | ||
| Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element. | Q36781988 | ||
| A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation | Q37248409 | ||
| Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion | Q37353803 | ||
| Cervical carcinoma and human cytomegalovirus | Q38287008 | ||
| NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation | Q38342724 | ||
| Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes | Q39602194 | ||
| Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters | Q39879958 | ||
| Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation | Q40018293 | ||
| Distinct functional properties of IkappaB alpha and IkappaB beta | Q40023354 | ||
| Cytomegalovirus and atherosclerosis | Q40375291 | ||
| Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha | Q40401245 | ||
| Severe liver degeneration in mice lacking the IkappaB kinase 2 gene | Q40962152 | ||
| Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid | Q41107899 | ||
| Rel/NF-kappaB/IkappaB proteins and cancer | Q41171323 | ||
| The human cytomegalovirus major immediate-early gene | Q41454473 | ||
| Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. | Q41565250 | ||
| Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase | Q41644582 | ||
| Nuclear factor kappaB subunits induce epithelial cell growth arrest | Q41756058 | ||
| Limb and skin abnormalities in mice lacking IKKalpha | Q42470314 | ||
| IKKalpha controls formation of the epidermis independently of NF-kappaB. | Q42502421 | ||
| Nuclear factor-kappaB is selectively and markedly activated in humans with unstable angina pectoris | Q43493913 | ||
| Activation of I kappa b kinase by herpes simplex virus type 1. A novel target for anti-herpetic therapy | Q43626729 | ||
| Stable expression of functional human cytomegalovirus immediate-early proteins IE1 and IE2 in HeLa cells | Q43796828 | ||
| I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function | Q43950649 | ||
| Cytomegalovirus associated inflammatory heart muscle disease. | Q44761783 | ||
| Human cytomegalovirus infection and expression in human malignant glioma. | Q44991512 | ||
| A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease: the atherosclerosis risk in communities (ARIC) study | Q45741610 | ||
| Role of Rel/NF-kappaB transcription factors during the outgrowth of the vertebrate limb. | Q46700056 | ||
| A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus | Q48378635 | ||
| Sp1 as a target site for metal-induced perturbations of transcriptional regulation of developmental brain gene expression | Q48443106 | ||
| Multiple proteolytic systems, including the proteasome, contribute to CFTR processing | Q50337154 | ||
| Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis. | Q52188586 | ||
| Reduced mRNA expression of the DNA demethylase, MBD2, in human colorectal and stomach cancers. | Q53417456 | ||
| Cytomegalovirus as a possible cause of a disease resembling infectious mononucleosis. | Q54641160 | ||
| Polymerase chain reaction to detect human cytomegalovirus in livers of infants with neonatal hepatitis | Q55036966 | ||
| Human cytomegalovirus infection of the major leukocyte subpopulations and evidence for initial viral replication in polymorphonuclear leukocytes from viremic patients | Q67506305 | ||
| High rate of concurrent genital infections with human cytomegalovirus and human papillomaviruses in cervical cancer patients | Q70466647 | ||
| Potential role of human cytomegalovirus and p53 interaction in coronary restenosis | Q72041267 | ||
| I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B | Q72571349 | ||
| Host response to cytomegalovirus infection as a determinant of susceptibility to coronary artery disease: sex-based differences in inflammation and type of immune response | Q73186322 | ||
| Characterization of the recombinant IKK1/IKK2 heterodimer. Mechanisms regulating kinase activity | Q73819243 | ||
| High anti-cytomegalovirus (CMV) IgG antibody titer is associated with coronary artery disease and may predict post-coronary balloon angioplasty restenosis | Q74471681 | ||
| Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices | Q74591086 | ||
| Human cytomegalovirus binding to human monocytes induces immunoregulatory gene expression | Q77320669 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| Cytomegalovirus | Q6946 | ||
| P304 | page(s) | 4498-4507 | |
| P577 | publication date | 2004-05-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Activation of the NF-kappaB pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter | |
| P478 | volume | 78 |
| Q35347846 | A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection |
| Q40147737 | Activation of the virus-induced IKK/NF-kappaB signalling axis is critical for the replication of human cytomegalovirus in quiescent cells. |
| Q33862714 | Adenoviral targeting of gene expression to tumors |
| Q92809182 | Bright and Early: Inhibiting Human Cytomegalovirus by Targeting Major Immediate-Early Gene Expression or Protein Function |
| Q33326039 | Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic mandibular development |
| Q36517563 | Cytomegalovirus inhibition of embryonic mouse tooth development: a model of the human amelogenesis imperfecta phenocopy |
| Q90747910 | Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7 |
| Q33645055 | Cytomegalovirus, Macrophages and Breast Cancer. |
| Q33256757 | Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model |
| Q36207868 | Dendritic cells in viral pathogenesis: protective or defective? |
| Q34545941 | Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation |
| Q90748167 | Expanding the Known Functional Repertoire of the Human Cytomegalovirus pp71 Protein |
| Q46486801 | Geldanamycin, a potent and specific inhibitor of Hsp90, inhibits gene expression and replication of human cytomegalovirus |
| Q38694359 | Global Screening of Antiviral Genes that Suppress Baculovirus Transgene Expression in Mammalian Cells |
| Q33701853 | HCMV IL-10 suppresses cytokine expression in monocytes through inhibition of nuclear factor-kappaB. |
| Q37611836 | HCMV reprogramming of infected monocyte survival and differentiation: a Goldilocks phenomenon |
| Q41918747 | HCMV utilizes a non-traditional STAT1 activation cascade via signaling through EGFR and integrins to efficiently promote the motility, differentiation, and polarization of infected monocytes |
| Q34178155 | Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling |
| Q35167034 | Heteromerization of human cytomegalovirus encoded chemokine receptors |
| Q39913109 | Hexamethylene bisacetamide can convert nonpermissive human cells to a permissive state for expressing the major immediate-early genes of human cytomegalovirus by up-regulating NF-kappaB activity |
| Q89862076 | Human Cytomegalovirus (HCMV) Reactivation in the Mammary Gland Induces a Proinflammatory Cytokine Shift in Breast Milk |
| Q41919640 | Human Cytomegalovirus IE2 86 kDa Protein Induces STING Degradation and Inhibits cGAMP-Mediated IFN-β Induction |
| Q33912815 | Human Cytomegalovirus Latency: Approaching the Gordian Knot |
| Q40303671 | Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-κB-Activating Factors through Direct Downregulation of IKKα and IKKβ. |
| Q36736892 | Human Cytomegalovirus Promotes Survival of Infected Monocytes via a Distinct Temporal Regulation of Cellular Bcl-2 Family Proteins |
| Q39100413 | Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells. |
| Q37548510 | Human Cytomegalovirus US28: a functionally selective chemokine binding receptor |
| Q39291106 | Human cytomegalovirus IE86 attenuates virus- and tumor necrosis factor alpha-induced NFkappaB-dependent gene expression |
| Q28474716 | Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA |
| Q39321145 | Human cytomegalovirus blocks tumor necrosis factor alpha- and interleukin-1beta-mediated NF-kappaB signaling |
| Q51976108 | Human cytomegalovirus immediate-early-gene expression disrupts embryogenesis in transgenic Drosophila. |
| Q33964039 | Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. |
| Q37145244 | Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirus |
| Q98664285 | Identification of a novel signaling complex containing host chemokine receptor CXCR4, Interleukin-10 receptor, and human cytomegalovirus US27 |
| Q36414448 | Infection of vascular endothelial cells with human cytomegalovirus under fluid shear stress reveals preferential entry and spread of virus in flow conditions simulating atheroprone regions of the artery |
| Q35940905 | Inhibition of IKKα by BAY61-3606 Reveals IKKα-Dependent Histone H3 Phosphorylation in Human Cytomegalovirus Infected Cells |
| Q39599295 | Inhibition of the FACT Complex Reduces Transcription from the Human Cytomegalovirus Major Immediate Early Promoter in Models of Lytic and Latent Replication |
| Q54597465 | Interaction of the human cytomegalovirus particle with the host cell induces hypoxia-inducible factor 1 alpha. |
| Q47147600 | Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection |
| Q35024244 | Lipopolysaccharide, tumor necrosis factor alpha, or interleukin-1beta triggers reactivation of latent cytomegalovirus in immunocompetent mice |
| Q33854683 | Metabolomics in drug target discovery |
| Q36049383 | MicroRNA silencing improves the tumor specificity of adenoviral transgene expression |
| Q57009346 | Modulation of the NFκb Signalling Pathway by Human Cytomegalovirus |
| Q41955869 | Murine cytomegalovirus virion-associated protein M45 mediates rapid NF-κB activation after infection |
| Q42065930 | NF-kappaB-mediated activation of the chemokine CCL22 by the product of the human cytomegalovirus gene UL144 escapes regulation by viral IE86. |
| Q42174351 | NF-κB, CRE and YY1 elements are key functional regulators of CMV promoter-driven transient gene expression in CHO cells |
| Q34793671 | New cell-signaling pathways for controlling cytomegalovirus replication |
| Q40311765 | Nicotine treatment alters NF-kappaB expression in human cytomegalovirus-infected ARPE-19 cells |
| Q40481090 | Posttranscriptional suppression of interleukin-6 production by human cytomegalovirus. |
| Q28193489 | Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression |
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| Q90051675 | Pseudorabies virus infection of epithelial cells leads to persistent but aberrant activation of the NF-κB pathway, inhibiting hallmark NF-κB-induced pro-inflammatory gene expression |
| Q38760564 | Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappaB binding sites in the enhancer |
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| Q40303024 | Stimulation of interferon-beta gene expression by human cytomegalovirus via nuclear factor kappa B and phosphatidylinositol 3-kinase pathway |
| Q54538485 | TNF-α expression in Schwann cells is induced by LPS and NF-κB-dependent pathways. |
| Q82858263 | The Elk-1 and serum response factor binding sites in the major immediate-early promoter of human cytomegalovirus are required for efficient viral replication in quiescent cells and compensate for inactivation of the NF-kappaB sites in proliferating |
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| Q41776844 | The SCHOOL of nature: IV. Learning from viruses |
| Q58559675 | The Viral Tegument Protein pp65 Impairs Transcriptional Upregulation of IL-1β by Human Cytomegalovirus through Inhibition of NF-kB Activity |
| Q39462585 | The cytomegaloviral protein pUL138 acts as potentiator of tumor necrosis factor (TNF) receptor 1 surface density to enhance ULb'-encoded modulation of TNF-α signaling |
| Q34594875 | The human cytomegalovirus UL26 protein antagonizes NF-κB activation |
| Q35857513 | The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha |
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