Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death

scientific article published on 18 August 2009

Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109.050443
P8608Fatcat IDrelease_hcdehgprcja3pfnef3iv42wmkm
P932PMC publication ID2781500
P698PubMed publication ID19690167

P50authorKelly V. RugglesQ38359897
Mahajabeen PadamseeQ54701821
Peter OelkersQ73241341
P2093author name stringOmar Jabado
Stephen L Sturley
Lisa Wilcox
Jeanne Garbarino
Aaron Turkish
Diana D'Ambrosio
Nicole Ramsey
P2860cites workCharacterization of Two Human Genes Encoding Acyl Coenzyme A:Cholesterol Acyltransferase-related EnzymesQ22003886
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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
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Summaries of Affymetrix GeneChip probe level dataQ27860888
A novel cytochrome b5-like domain is linked to the carboxyl terminus of the Saccharomyces cerevisiae delta-9 fatty acid desaturaseQ27930825
An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growthQ27931980
Synthesis of Triacylglycerols by the Acyl-Coenzyme A:Diacyl-Glycerol Acyltransferase Dga1p in Lipid Particles of the Yeast Saccharomyces cerevisiaeQ27933343
A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast.Q27933801
Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activityQ27934818
Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profileQ27935813
Transcriptional profiling identifies two members of the ATP-binding cassette transporter superfamily required for sterol uptake in yeastQ27939046
Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinaseQ27940004
Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamilyQ28118125
Yeast transformation: a model system for the study of recombinationQ28264331
Sterol esterification in yeast: a two-gene processQ28280662
ASNA-1 positively regulates insulin secretion in C. elegans and mammalian cellsQ28287432
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistanceQ28291556
Identification of a targeting factor for posttranslational membrane protein insertion into the ERQ28294726
Characterization of the murine phosphatidylethanolamine N-methyltransferase-2 geneQ28592992
Bacterial iron homeostasisQ29615095
The DGA1 gene determines a second triglyceride synthetic pathway in yeast.Q30667251
Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cellsQ31582971
limmaGUI: a graphical user interface for linear modeling of microarray dataQ33205531
affylmGUI: a graphical user interface for linear modeling of single channel microarray dataQ33233003
Lipid Synthesis During Sporulation of Saccharomyces cerevisiaeQ33785944
Intracellular lipid particles of eukaryotic cellsQ34040250
Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammalsQ34245400
Isolation and characterization of OLE1, a gene affecting fatty acid desaturation from Saccharomyces cerevisiae.Q34507873
Triglyceride accumulation protects against fatty acid-induced lipotoxicityQ34866329
Acetate Utilization and Macromolecular Synthesis During Sporulation of YeastQ35157175
Fatty acid-induced beta cell apoptosis: a link between obesity and diabetesQ35923385
Unsaturated fatty acids inhibit transcription of the sterol regulatory element-binding protein-1c (SREBP-1c) gene by antagonizing ligand-dependent activation of the LXR.Q35926317
Regulation of triglyceride metabolism. I. Eukaryotic neutral lipid synthesis: "Many ways to skin ACAT or a DGAT".Q36649458
Regulation of Triglyceride Metabolism. III. Emerging role of lipid droplet protein ADFP in health and diseaseQ36694766
Development of the FUN-1 family of fluorescent probes for vacuole labeling and viability testing of yeastsQ36869468
Saturated with fat: new perspectives on lipotoxicityQ37388367
Protein phosphatase type 2Calpha and 2Cbeta are involved in fatty acid-induced apoptosis of neuronal and endothelial cellsQ40279973
Regulation of reactive oxygen species (ROS) production by C18 fatty acids in Jurkat and Raji cells.Q40488322
Comparative toxicity of oleic acid and linoleic acid on Jurkat cells.Q40528132
Regulation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiaeQ41004914
A Yeast Mutant Showing Diagnostic Markers of Early and Late ApoptosisQ42065466
In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activityQ42167410
Novel mechanism of chronic exposure of oleic acid-induced insulin release impairment in rat pancreatic beta-cellsQ42496498
Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeastQ42583843
Oxygen stress: a regulator of apoptosis in yeastQ42797452
Palmitate-induced apoptosis can occur through a ceramide-independent pathwayQ43559742
Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetesQ43833528
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophagesQ44542540
A yeast strain lacking lipid particles bears a defect in ergosterol formationQ44904778
Homoeostatic systems for sterols and other lipidsQ46771462
Storage lipid synthesis is non-essential in yeastQ52544739
Ultrastructural studies of neutral lipid localisation in StreptomycesQ52870046
Metabolism of emulsions containing medium- and long-chain triglycerides or interesterified triglyceridesQ58199153
Regulation of phosphatidylethanolamine methyltransferase and phospholipid methyltransferase by phospholipid precursors in Saccharomyces cerevisiaeQ68062160
Lipid metabolism in Achlya: studies of lipid turnover during developmentQ68230468
Separation and Analysis of Phospholipids by Thin Layer ChromatographyQ72101573
An acyl-CoA:cholesterol acyltransferase (ACAT)-related gene is involved in the accumulation of triacylglycerols in Saccharomyces cerevisiaeQ73424914
Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phaseQ73918457
Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic ratsQ79372285
Use of mixture models in a microarray-based screening procedure for detecting differentially represented yeast mutantsQ83218424
P4510describes a project that useslimmaQ112236343
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
cell deathQ2383867
P304page(s)30994-31005
P577publication date2009-08-18
P1433published inJournal of Biological ChemistryQ867727
P1476titleSterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death
P478volume284

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