| scholarly article | Q13442814 |
| P50 | author | Stephen E. Gould | Q60729331 |
| P2093 | author name string | Domagoj Vucic | |
| Wayne J Fairbrother | |||
| Eugene Varfolomeev | |||
| Kerry Zobel | |||
| Harvey Wong | |||
| Kristina West | |||
| Bruno Alicke | |||
| J Michael Elliott | |||
| Justin M Scheer | |||
| Avi Ashkenazi | |||
| P2860 | cites work | A unified model for apical caspase activation | Q28609101 |
| The Bcl2 family: regulators of the cellular life-or-death switch | Q29614982 | ||
| NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation | Q29618715 | ||
| IAP proteins: blocking the road to death's door | Q29619844 | ||
| Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. | Q34124538 | ||
| The many roles of FAS receptor signaling in the immune system | Q34205697 | ||
| XIAP discriminates between type I and type II FAS-induced apoptosis | Q34205704 | ||
| Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes | Q34360719 | ||
| A common allosteric site and mechanism in caspases | Q34595353 | ||
| Alterations in the apoptotic machinery and their potential role in anticancer drug resistance | Q35567264 | ||
| Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies | Q35743108 | ||
| Caspase activation, inhibition, and reactivation: a mechanistic view | Q35845173 | ||
| Promoting apoptosis as a strategy for cancer drug discovery | Q36292878 | ||
| The inhibitors of apoptosis (IAPs) as cancer targets | Q36851057 | ||
| The inhibitor of apoptosis proteins as therapeutic targets in cancer | Q36975583 | ||
| Targeting the extrinsic apoptosis pathway in cancer | Q37169988 | ||
| IAP-targeted therapies for cancer | Q37302745 | ||
| Directing cancer cells to self-destruct with pro-apoptotic receptor agonists | Q37319386 | ||
| Cooperation of the agonistic DR5 antibody apomab with chemotherapy to inhibit orthotopic lung tumor growth and improve survival | Q39910426 | ||
| A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling | Q40033734 | ||
| A role for proapoptotic BID in the DNA-damage response | Q40381562 | ||
| Mechanisms and genes of cellular suicide | Q40605270 | ||
| Malonate-assisted purification of human caspases | Q46414574 | ||
| Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo | Q48548442 | ||
| Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma. | Q51788134 | ||
| The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest | Q57272464 | ||
| Development of novel drugs targeting inhibitors of apoptosis | Q83472151 | ||
| Mechanism of XIAP-mediated inhibition of caspase-9 | Q24296916 | ||
| IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis | Q24300707 | ||
| IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis | Q24300734 | ||
| c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation | Q24607621 | ||
| Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis | Q24609324 | ||
| Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family | Q24670396 | ||
| Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs | Q27643305 | ||
| Structural and functional analysis of the interaction between the agonistic monoclonal antibody Apomab and the proapoptotic receptor DR5 | Q27649718 | ||
| Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition | Q28115131 | ||
| The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins | Q28117866 | ||
| Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins | Q28117928 | ||
| Death receptors: signaling and modulation | Q28280897 | ||
| cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination | Q28284721 | ||
| Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis | Q28511080 | ||
| P433 | issue | 50 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | 34553-34560 | |
| P577 | publication date | 2009-10-23 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists | |
| P478 | volume | 284 |
| Q33618500 | Analysis of inhibitor of apoptosis protein family expression during mammary gland development |
| Q36604919 | Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation |
| Q37777758 | Antagonists of IAP proteins as cancer therapeutics |
| Q82038296 | Association of XIAP and P2X7 receptor expression with lymph node metastasis in papillary thyroid carcinoma |
| Q37502782 | Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression |
| Q39126075 | Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling |
| Q33968452 | Enhanced anti-tumor activity of a new curcumin-related compound against melanoma and neuroblastoma cells |
| Q42251118 | FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis. |
| Q35657414 | Fas death receptor signalling: roles of Bid and XIAP. |
| Q90089266 | Genomically informed small-molecule drugs overcome resistance to a sustained-release formulation of an engineered death receptor agonist in patient-derived tumor models |
| Q36219516 | Harnessing programmed cell death as a therapeutic strategy in rheumatic diseases |
| Q33869744 | Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells |
| Q53642353 | Human islet cells are killed by BID-independent mechanisms in response to FAS ligand. |
| Q38886482 | Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis |
| Q33632016 | Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. |
| Q47438495 | Inhibition of IAP (inhibitor of apoptosis) proteins represses inflammatory status via nuclear factor-kappa B pathway in murine endometriosis lesions |
| Q47221521 | Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy |
| Q34673169 | Inhibitor of apoptosis proteins (IAPs) may be effective therapeutic targets for treating endometriosis. |
| Q37875078 | Inhibitor of apoptosis proteins: fascinating biology leads to attractive tumor therapeutic targets |
| Q90250942 | LCL161, a SMAC-mimetic, Preferentially Radiosensitizes Human Papillomavirus-negative Head and Neck Squamous Cell Carcinoma |
| Q34912378 | Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells. |
| Q37269029 | NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppression |
| Q34022690 | New insights into apoptosis signaling by Apo2L/TRAIL. |
| Q33841579 | Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs) |
| Q47600992 | Pathways of tumor development and progression in drug-induced nonmelanoma skin cancer: a new hope or the next great confusion? |
| Q37784920 | Proapoptotic DR4 and DR5 signaling in cancer cells: toward clinical translation |
| Q39642704 | Smac mimetic compounds potentiate interleukin-1beta-mediated cell death |
| Q26864204 | Small-molecule SMAC mimetics as new cancer therapeutics |
| Q37980321 | Targeting IAP proteins for therapeutic intervention in cancer |
| Q33868788 | Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells |
| Q38937890 | Ubiquitination profiling identifies sensitivity factors for IAP antagonist treatment |
| Q38239689 | X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy. |
| Q28591258 | cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production |
| Q39266738 | cIAP2 represses IKKα/β-mediated activation of MDM2 to prevent p53 degradation |
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