SnoN activates p53 directly to regulate aging and tumorigenesis

scientific article published on 27 August 2012

SnoN activates p53 directly to regulate aging and tumorigenesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1474-9726.2012.00857.X
P932PMC publication ID3897278
P698PubMed publication ID22805162
P5875ResearchGate publication ID229159335

P2093author name stringKunxin Luo
Deng Pan
Qingwei Zhu
Irina M Conboy
Michael J Conboy
P2860cites workUsing mice to examine p53 functions in cancer, aging, and longevityQ37748214
Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissuesQ38293690
Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration.Q39766282
Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.Q40649890
A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.Q51790182
Regulation of p53: intricate loops and delicate balancesQ78674009
Negative feedback regulation of TGF-beta signaling by the SnoN oncoproteinQ22010706
PML regulates p53 acetylation and premature senescence induced by oncogenic RasQ22254666
The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteinsQ24302423
Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signalingQ24316291
Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cellsQ24534996
Isolation of human cDNA clones of ski and the ski-related gene, snoQ24635631
Two faces of p53: aging and tumor suppressionQ24681014
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferationQ28117650
Atmospheric carbon dioxide concentrations over the past 60 million yearsQ28144787
PML interaction with p53 and its role in apoptosis and replicative senescenceQ28204830
SnoN functions as a tumour suppressor by inducing premature senescenceQ28585092
PML is a direct p53 target that modulates p53 effector functionsQ28586691
Blinded by the Light: The Growing Complexity of p53Q29547590
Modes of p53 regulationQ29615657
Structure, dynamics and functions of promyelocytic leukaemia nuclear bodiesQ29620390
p53 mutant mice that display early ageing-associated phenotypesQ29622826
Modulation of mammalian life span by the short isoform of p53.Q30312095
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR.Q30480527
"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normallyQ34369829
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells.Q34786450
Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesisQ34992779
SnoN in mammalian development, function and diseasesQ35069771
PML is induced by oncogenic ras and promotes premature senescenceQ35201220
Dual role of SnoN in mammalian tumorigenesisQ35641680
Mouse models of senile osteoporosisQ36089638
p53 brings a new twist to the Smad signaling networkQ37204667
Ski and SnoN, potent negative regulators of TGF-beta signalingQ37359949
Tied up in loops: positive and negative autoregulation of p53.Q37746500
P433issue5
P304page(s)902-911
P577publication date2012-08-27
P1433published inAging CellQ2221073
P1476titleSnoN activates p53 directly to regulate aging and tumorigenesis
P478volume11

Reverse relations

cites work (P2860)
Q57050279A novel system-level approach using RNA-sequencing data identifies miR-30-5p and miR-142a-5p as key regulators of apoptosis in myocardial infarction
Q36994817Exploring Transcription Factors-microRNAs Co-regulation Networks in Schizophrenia
Q40375353Modulation of host cell SUMOylation facilitates efficient development of Plasmodium berghei and Toxoplasma gondii
Q37745263NGS-based transcriptome profiling reveals biomarkers for companion diagnostics of the TGF-β receptor blocker galunisertib in HCC.
Q49383418Relevance of the p53-MDM2 axis to aging
Q36992698SnoN Antagonizes the Hippo Kinase Complex to Promote TAZ Signaling during Breast Carcinogenesis
Q37498907SnoN in regulation of embryonic development and tissue morphogenesis
Q33616166Stem cells as vehicles for youthful regeneration of aged tissues.
Q98288395The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A
Q90374946The regulatory protein SnoN antagonizes activin/Smad2 protein signaling and thereby promotes adipocyte differentiation and obesity in mice
Q62060038Transcriptional cofactors Ski and SnoN are major regulators of the TGF-β/Smad signaling pathway in health and disease

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