Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes

scientific article published on March 2013

Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/CS20120239
P932PMC publication ID3903000
P698PubMed publication ID23057846
P5875ResearchGate publication ID232234448

P50authorAnna DominiczakQ4766963
Andrea DegasperiQ55095173
Ian P SaltQ56876361
Michael P. MurphyQ37391317
Christian DellesQ43096626
P2093author name stringWilliam H Miller
Angela Logan
Carlene A Hamilton
Hagar A Ibrahim
Jane A Dymott
Ruth M Mackenzie
P2860cites workEffects of nitric oxide and superoxide on relaxation in human artery and veinQ56970954
Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteriesQ73762643
Possible involvement of the alpha1 isoform of 5'AMP-activated protein kinase in oxidative stress-stimulated glucose transport in skeletal muscle.Q44802854
Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosisQ44954085
Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo. Role of mitochondrial reactive nitrogen speciesQ44987425
AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress.Q46037787
Inhibition of tumor necrosis factor alpha-stimulated monocyte adhesion to human aortic endothelial cells by AMP-activated protein kinaseQ46359191
Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cellsQ46523954
Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cellsQ46738375
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cellsQ46870176
AMPKalpha1 regulates the antioxidant status of vascular endothelial cellsQ47801068
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stressQ24633606
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Coronary heart disease in patients with diabetes: part I: recent advances in prevention and noninvasive managementQ28218905
Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental toolsQ28241521
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinaseQ28567006
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damageQ29616101
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteriaQ29616614
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells?Q29618095
AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomesQ34059872
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinaseQ34236772
Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veinsQ34333678
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.Q34438345
Mitochondria as signaling organelles in the vascular endotheliumQ34600173
Early determinants of H2O2-induced endothelial dysfunctionQ35070086
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrixQ35549813
Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratioQ35888893
Coronary heart disease in patients with diabetes: part II: recent advances in coronary revascularization.Q36732931
Mitochondrial dysfunction in atherosclerosis.Q36749083
Comorbidity in patients undergoing coronary artery bypass graft surgery: impact on outcome and implications for cardiac rehabilitationQ37234346
AMPK: a key regulator of energy balance in the single cell and the whole organism.Q37249357
Activation and signaling by the AMP-activated protein kinase in endothelial cellsQ37553770
Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cellsQ40331177
Identification of nitric oxide as an endogenous activator of the AMP-activated protein kinase in vascular endothelial cellsQ41901421
Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinaseQ42075557
AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633Q42582636
The regulation of AMP-activated protein kinase by H(2)O(2).Q42825708
Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthaseQ43952389
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cellsQ44468960
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.Q44489729
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
patientQ181600
endotheliumQ111140
reactive oxygen speciesQ424361
coronary artery diseaseQ844935
P304page(s)403-411
P577publication date2013-03-01
P1433published inClinical ScienceQ372419
P1476titleMitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes
P478volume124

Reverse relations

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