scholarly article | Q13442814 |
P356 | DOI | 10.1161/CIRCRESAHA.108.187567 |
P8608 | Fatcat ID | release_ycnii2ruk5dhjlv3igexc3qlb4 |
P932 | PMC publication ID | 2761102 |
P698 | PubMed publication ID | 19131647 |
P5875 | ResearchGate publication ID | 23766421 |
P50 | author | Ming-Daw Tsai | Q40453365 |
P2093 | author name string | Wei Sun | |
Zhen Chen | |||
Yi Zhu | |||
Mei-I Su | |||
Pang-Hung Hsu | |||
John Y-J Shyy | |||
Yi Fu | |||
Songqin Pan | |||
I-Chen Peng | |||
Kathryn DeFea | |||
P2860 | cites work | Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase | Q40622130 |
Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay | Q41758439 | ||
Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities | Q41764509 | ||
Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase | Q42437220 | ||
Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase | Q43568413 | ||
Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A. | Q43812771 | ||
Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism | Q44182985 | ||
Adiponectin stimulates production of nitric oxide in vascular endothelial cells. | Q44565932 | ||
Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors | Q44846597 | ||
Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle | Q44987298 | ||
AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress. | Q46037787 | ||
Statins activate AMP-activated protein kinase in vitro and in vivo | Q46230916 | ||
Estradiol-mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase. | Q46557763 | ||
Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling | Q46847423 | ||
AMP-activated protein kinase subunit interactions: beta1:gamma1 association requires beta1 Thr-263 and Tyr-267. | Q46851056 | ||
Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway. | Q53551231 | ||
Modulation of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase activity by phosphorylation. Role of serine 871. | Q54638032 | ||
Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells. | Q55043111 | ||
Specificity determinants for the AMP-activated protein kinase and its plant homologue analysed using synthetic peptides. | Q55065507 | ||
Enhanced electron flux and reduced calmodulin dissociation may explain "calcium-independent" eNOS activation by phosphorylation | Q57219989 | ||
Endothelial nitric-oxide synthase (type III) is activated and becomes calcium independent upon phosphorylation by cyclic nucleotide-dependent protein kinases | Q73441813 | ||
AMP-activated protein kinase phosphorylation of endothelial NO synthase | Q74456171 | ||
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt | Q22010149 | ||
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation | Q22010150 | ||
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling | Q22241925 | ||
Regulation of AMP-activated protein kinase by a pseudosubstrate sequence on the gamma subunit | Q24294651 | ||
The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity | Q24554361 | ||
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor | Q28299224 | ||
Specificity and mechanism of action of some commonly used protein kinase inhibitors | Q28344791 | ||
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine | Q29547539 | ||
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? | Q29618095 | ||
Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635. | Q33184040 | ||
Mammalian nitric oxide synthases | Q33631306 | ||
Enzymatic function of nitric oxide synthases | Q33847576 | ||
Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. | Q33950554 | ||
Nitric oxide insufficiency, platelet activation, and arterial thrombosis | Q34234301 | ||
5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments | Q35070875 | ||
eNOS at a glance | Q35782010 | ||
Endothelial function: cardiac events | Q36019119 | ||
Endothelial-cardiomyocyte interactions in cardiac development and repair | Q36387870 | ||
Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation | Q36535244 | ||
AMP-activated protein kinase as a drug target. | Q36551887 | ||
AMP-activated protein kinase in the heart: role during health and disease | Q36749088 | ||
Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli. | Q38292157 | ||
P433 | issue | 4 | |
P921 | main subject | endothelium | Q111140 |
phosphorylation | Q242736 | ||
P304 | page(s) | 496-505 | |
P577 | publication date | 2009-01-08 | |
P1433 | published in | Circulation Research | Q2599020 |
P1476 | title | AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633 | |
P478 | volume | 104 |
Q36527961 | AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension |
Q39331294 | AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System. |
Q37864217 | AMP-activated protein kinase and metabolic control |
Q54618184 | AMP-activated protein kinase inhibits homocysteine-induced dysfunction and apoptosis in endothelial progenitor cells. |
Q52430975 | AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension. |
Q33689169 | AMPK activation--protean potential for boosting healthspan |
Q47369070 | AMPK and cardiac remodelling. |
Q34807222 | AMPK in cardiovascular health and disease |
Q35094436 | AMPK inhibition in health and disease |
Q26995682 | AMPK: a cellular metabolic and redox sensor. A minireview |
Q60921233 | AMPK: a therapeutic target of heart failure-not only metabolism regulation |
Q34059872 | AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes |
Q48242829 | Activation of AMP-activated protein kinase by metformin ablates angiotensin II-induced endoplasmic reticulum stress and hypertension in mice in vivo |
Q33796165 | Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase |
Q33533561 | Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts |
Q34502017 | Activation of AMPK stimulates heme oxygenase-1 gene expression and human endothelial cell survival |
Q42075557 | Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase |
Q38450680 | Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries. |
Q38014474 | Adipokines and the cardiovascular system: mechanisms mediating health and disease |
Q35859734 | Adiponectin and cardiovascular health: an update |
Q30370241 | Adiponectin and insulin cross talk: the microvascular connection. |
Q26821925 | Adiponectin as a potential biomarker of vascular disease |
Q41472144 | Adrenocorticotropic Hormone and PI3K/Akt Inhibition Reduce eNOS Phosphorylation and Increase Cortisol Biosynthesis in Long-Term Hypoxic Ovine Fetal Adrenal Cortical Cells |
Q38228952 | Advances in endothelial shear stress proteomics. |
Q37012154 | Asiatic Acid Protects against Cardiac Hypertrophy through Activating AMPKα Signalling Pathway |
Q123351354 | Asiatic acid: a review on its polypharmacological properties and therapeutic potential against various Maladies |
Q55035878 | Atorvastatin acutely reduces the reactivity to spasmogens in rat aorta: implication of the inhibition of geranylgeranylation and MYPT-1 phosphorylation. |
Q34761461 | Atorvastatin enhance efficacy of mesenchymal stem cells treatment for swine myocardial infarction via activation of nitric oxide synthase. |
Q44487639 | Atorvastatin inhibits homocysteine-induced endoplasmic reticulum stress through activation of AMP-activated protein kinase |
Q47916169 | Camptothecin promotes the production of nitric oxide that triggers subsequent S-nitrosoproteome-mediated signaling cascades in endothelial cells. |
Q34383575 | Cardiovascular impact of drugs used in the treatment of diabetes |
Q28081013 | Cellular and molecular biology of aging endothelial cells |
Q37173867 | Cellular signaling and NO production |
Q34918014 | Chronic activation of AMP-activated protein kinase prevents 20-hydroxyeicosatetraenoic acid-induced endothelial dysfunction. |
Q90448263 | Chronic dosing with metformin plus bosentan decreases in vitro pulmonary artery contraction from isolated arteries in adults with pulmonary hypertension |
Q39529407 | Comparison of cardioprotective efficacy resulting from a combination of atorvastatin and ischaemic post-conditioning in diabetic and non-diabetic rats |
Q35112954 | Compound C stimulates heme oxygenase-1 gene expression via the Nrf2-ARE pathway to preserve human endothelial cell survival |
Q46826234 | Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release |
Q41913584 | Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L. |
Q26864590 | Differential Role of Leptin and Adiponectin in Cardiovascular System |
Q39226994 | Dose dependent effects of cadmium on tumor angiogenesis. |
Q89861714 | Early intervention with Didang decoction delays macrovascular lesions in diabetic rats through regulating AMP-activated protein kinase signaling pathway |
Q97523709 | Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related Diseases |
Q28394686 | Effects of AMP-activated protein kinase in cerebral ischemia |
Q54485839 | Effects of acute and chronic atorvastatin on cardioprotection of ischemic postconditioning in isolated rat hearts. |
Q41365636 | Effects of metformin in experimental stroke |
Q38849620 | Effects of shear stress on endothelial cells: go with the flow |
Q58742216 | Endothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation |
Q36417731 | Endothelial Gata5 transcription factor regulates blood pressure |
Q38082465 | Endothelial dysfunction in (pre)diabetes: characteristics, causative mechanisms and pathogenic role in type 2 diabetes |
Q26852572 | Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like receptor family pyrin domain-containing protein 3 inflammasome in atherosclerosis |
Q89870340 | Endothelial mechanobiology |
Q33841044 | Endothelial nitric oxide synthase is central to skeletal muscle metabolic regulation and enzymatic signaling during exercise in vivo |
Q38597218 | Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms |
Q26752894 | Endothelial nitric oxide synthase: a potential therapeutic target for cerebrovascular diseases |
Q54639442 | Endothelium-dependent vasorelaxation to the AMPK activator AICAR is enhanced in aorta from hypertensive rats and is NO and EDCF dependent. |
Q35769564 | Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans |
Q51722308 | Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPKα2. |
Q28536018 | Green tea extract increases mRNA expression of enzymes which influence epigenetic marks in newborn female offspring from undernourished pregnant mother |
Q34384055 | Heparin cofactor II, a serine protease inhibitor, promotes angiogenesis via activation of the AMP-activated protein kinase-endothelial nitric-oxide synthase signaling pathway. |
Q55070081 | High-fat diet induces endothelial dysfunction through a down-regulation of the endothelial AMPK-PI3K-Akt-eNOS pathway. |
Q42591269 | How to protect liver graft with nitric oxide |
Q35229424 | Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis |
Q35173223 | Impaired expression of uncoupling protein 2 causes defective postischemic angiogenesis in mice deficient in AMP-activated protein kinase α subunits |
Q83749924 | Implication of AMP-activated protein kinase in transient receptor potential vanilloid type 1-mediated activation of endothelial nitric oxide synthase |
Q51145526 | Kidney-specific genetic deletion of both AMPK α-subunits causes salt and water wasting. |
Q54517073 | Liver X receptor agonist alleviated high glucose-induced endothelial progenitor cell dysfunction via inhibition of reactive oxygen species and activation of AMP-activated protein kinase. |
Q40361468 | Mathematical model for shear stress dependent NO and adenine nucleotide production from endothelial cells |
Q57822222 | Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease |
Q57822218 | Mechanisms of Vascular Aging |
Q35324163 | Mechanistic analysis of nonoxygenated hypothermic machine perfusion's protection on warm ischemic kidney uncovers greater eNOS phosphorylation and vasodilation |
Q38238017 | Mechanistic perspectives of calorie restriction on vascular homeostasis |
Q46478331 | Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission |
Q34616393 | Metformin exaggerates phenylephrine-induced AMPK phosphorylation independent of CaMKKβ and attenuates contractile response in endothelium-denuded rat aorta |
Q34505650 | Metformin is not just an antihyperglycaemic drug but also has protective effects on the vascular endothelium |
Q35599981 | Metformin treatment improves erectile function in an angiotensin II model of erectile dysfunction. |
Q41661696 | Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats. |
Q37518840 | Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes |
Q37655580 | Molecular mechanisms underlying the activation of eNOS. |
Q50848558 | Molecular modeling and simulation of the human eNOS reductase domain, an enzyme involved in the release of vascular nitric oxide. |
Q54192529 | Morus alba extract modulates blood pressure homeostasis through eNOS signaling. |
Q63976786 | Muscle Insulin Resistance and the Inflamed Microvasculature: Fire from Within |
Q36422628 | N-cadherin coordinates AMP kinase-mediated lung vascular repair |
Q33943727 | New insight into adiponectin role in obesity and obesity-related diseases |
Q58121145 | New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis |
Q47807793 | Nitric oxide-heat shock protein axis in menopausal hot flushes: neglected metabolic issues of chronic inflammatory diseases associated with deranged heat shock response. |
Q37887771 | Nitric oxide: a guardian for vascular grafts? |
Q38876119 | Omics-based approaches to understand mechanosensitive endothelial biology and atherosclerosis |
Q36410664 | PPARδ activation protects endothelial function in diabetic mice. |
Q58599881 | PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis |
Q33754395 | Perivascular adipose tissue inhibits endothelial function of rat aortas via caveolin-1. |
Q37671282 | Perivascular fat, AMP-activated protein kinase and vascular diseases. |
Q42723806 | Phosphorylation of CHOP (C/EBP Homologous Protein) by the AMP-Activated Protein Kinase Alpha 1 in Macrophages Promotes CHOP Degradation and Reduces Injury-Induced Neointimal Disruption In Vivo |
Q51284981 | Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. |
Q36407484 | Pim1 kinase promotes angiogenesis through phosphorylation of endothelial nitric oxide synthase at Ser-633. |
Q35812975 | Plasticity of microvascular oxygenation control in rat fast-twitch muscle: effects of experimental creatine depletion |
Q34586633 | Platelet-endothelial cell adhesion molecule-1 regulates endothelial NO synthase activity and localization through signal transducers and activators of transcription 3-dependent NOSTRIN expression |
Q45981849 | Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase. |
Q54393648 | Prolonged AMP-activated protein kinase induction impairs vascular functions. |
Q50074049 | Protective Effects of Methotrexate against Proatherosclerotic Cytokines: A Review of the Evidence. |
Q37793322 | Protective effects of AMP-activated protein kinase in the cardiovascular system |
Q34718182 | Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats |
Q35925959 | Regulation of NAD(P)H oxidases by AMPK in cardiovascular systems |
Q36206138 | Regulation of Overnutrition-Induced Cardiac Inflammatory Mechanisms |
Q36249066 | Regulation of cardiac miR-208a, an inducer of obesity, by rapamycin and nebivolol |
Q38158116 | Regulation of eNOS enzyme activity by posttranslational modification. |
Q53065024 | Regulatory effect of AMP-activated protein kinase on pulmonary hypertension induced by chronic hypoxia in rats: in vivo and in vitro studies. |
Q59135667 | Repurposing existing drugs for cardiovascular risk management: a focus on methotrexate |
Q36860450 | Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension |
Q34570751 | Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism |
Q28483611 | Role of Ca2+ in the control of H2O2-modulated phosphorylation pathways leading to eNOS activation in cardiac myocytes |
Q33840570 | Role of the energy sensor AMP-activated protein kinase in renal physiology and disease |
Q33933093 | Shear stress, SIRT1, and vascular homeostasis |
Q37502786 | Shear-induced endothelial mechanotransduction: the interplay between reactive oxygen species (ROS) and nitric oxide (NO) and the pathophysiological implications |
Q47292284 | Snf1 (Sucrose Nonfermenting 1)-Related Kinase Promotes Angiogenesis In Vivo |
Q37992099 | Submaximal PPARγ activation and endothelial dysfunction: new perspectives for the management of cardiovascular disorders |
Q38808467 | Targeting the NO/superoxide ratio in adipose tissue: relevance to obesity and diabetes management |
Q36563042 | The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches |
Q92617115 | Therapeutic Potential of Oxytocin in Atherosclerotic Cardiovascular Disease: Mechanisms and Signaling Pathways |
Q28534586 | Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death |
Q42943354 | Tongxinluo reduces myocardial no-reflow and ischemia-reperfusion injury by stimulating the phosphorylation of eNOS via the PKA pathway |
Q90308406 | VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1 |
Q38419222 | Vascular AMPK as an attractive target in the treatment of vascular complications of obesity. |
Q42482105 | α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation |
Search more.