scholarly article | Q13442814 |
P2093 | author name string | Miao Zhang | |
Qilong Wang | |||
Shengnan Wu | |||
Zhonglin Xie | |||
Ming-Hui Zou | |||
Gloria Torres | |||
Changhan Ouyang | |||
P2860 | cites work | C-peptide activates AMPKα and prevents ROS-mediated mitochondrial fission and endothelial apoptosis in diabetes | Q37251110 |
In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I | Q37267054 | ||
Endothelial cell-specific liver kinase B1 deletion causes endothelial dysfunction and hypertension in mice in vivo | Q37678614 | ||
Mitochondrial dynamics in peripheral neuropathies | Q38175425 | ||
Hypertension and insulin resistance: implications of mitochondrial dysfunction | Q38272560 | ||
Redox Homeostasis and Mitochondrial Dynamics. | Q38545789 | ||
AMPK regulates ER morphology and function in stressed pancreatic β-cells via phosphorylation of DRP1. | Q39104609 | ||
Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis | Q39937641 | ||
Direct Endothelial Nitric Oxide Synthase Activation Provides Atheroprotection in Diabetes-Accelerated Atherosclerosis. | Q40791385 | ||
AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633 | Q42582636 | ||
Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice | Q42809915 | ||
Primary preventive effect of metformin upon atherosclerosis in patients with type 2 diabetes mellitus | Q43199472 | ||
Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes | Q44882775 | ||
Estradiol-mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase. | Q46557763 | ||
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells | Q46870176 | ||
Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase | Q46917092 | ||
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction. | Q50952957 | ||
Inhibition to DRP1 translocation can mitigate p38 MAPK-signaling pathway activation in GMC induced by hyperglycemia. | Q52952699 | ||
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. | Q53194946 | ||
Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis. | Q53648299 | ||
NADPH Oxidase 1 Plays a Key Role in Diabetes Mellitus–Accelerated Atherosclerosis | Q56991358 | ||
Dietary supplementation with fish oil alters the expression levels of proteins governing mitochondrial dynamics and prevents high-fat diet-induced endothelial dysfunction | Q87771640 | ||
Dysregulation of HSG triggers vascular proliferative disorders | Q24301690 | ||
Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress | Q27330478 | ||
Biochemistry and molecular cell biology of diabetic complications | Q28131781 | ||
Mitochondrial fusion and fission in cell life and death | Q28299119 | ||
Redox regulation of endothelial cell fate | Q28392484 | ||
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy | Q29615616 | ||
Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus | Q29616284 | ||
Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo | Q33675689 | ||
Activation of NAD(P)H oxidase by tryptophan-derived 3-hydroxykynurenine accelerates endothelial apoptosis and dysfunction in vivo. | Q33922718 | ||
AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes | Q34059872 | ||
Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis | Q34447321 | ||
Oxidative stress as a mechanism of added sugar-induced cardiovascular disease | Q34452521 | ||
Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology | Q34479807 | ||
TZDs reduce mitochondrial ROS production and enhance mitochondrial biogenesis | Q34601950 | ||
Hypochlorous acid via peroxynitrite activates protein kinase Cθ and insulin resistance in adipocytes | Q34665300 | ||
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice | Q35043474 | ||
Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury | Q35056744 | ||
Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis | Q35114963 | ||
Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus | Q35144163 | ||
Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells. | Q35529133 | ||
Drp1-mediated mitochondrial abnormalities link to synaptic injury in diabetes model | Q35532253 | ||
Disruption of renal tubular mitochondrial quality control by Myo-inositol oxygenase in diabetic kidney disease | Q35658612 | ||
Mitochondrial fission contributes to mitochondrial dysfunction and insulin resistance in skeletal muscle | Q35665651 | ||
Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells | Q35754670 | ||
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions | Q35781399 | ||
Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy | Q36225147 | ||
Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. | Q36642535 | ||
Effects of metformin versus glipizide on cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease | Q36782688 | ||
Endothelial mitochondria: contributing to vascular function and disease | Q36803365 | ||
Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. | Q37245109 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | metformin | Q19484 |
mitochondrial fission | Q6881852 | ||
atherosclerosis | Q12252367 | ||
P304 | page(s) | 193-205 | |
P577 | publication date | 2016-10-13 | |
P1433 | published in | Diabetes | Q895262 |
P1476 | title | Metformin Suppresses Diabetes-Accelerated Atherosclerosis via the Inhibition of Drp1-Mediated Mitochondrial Fission | |
P478 | volume | 66 |
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