A polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction

scientific article published on March 2013

A polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1097/FPC.0B013E32835D247F
P932PMC publication ID3912740
P698PubMed publication ID23337848
P5875ResearchGate publication ID234823311

P50authorMarkus PerolaQ28050040
Mordechai MuszkatQ43141188
Jussi PostiQ55572519
Mika ScheininQ60732950
Daniel KurnikQ85342261
Gbenga G SofoworaQ117270558
P2093author name stringAmir Snapir
C Michael Stein
Perttu Salo
Saku Ruohonen
Laura Valve
P2860cites workMeta-analysis in genome-wide association studiesQ24273398
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
A haplotype map of the human genomeQ24679827
PI3K and PKC contribute to membrane depolarization mediated by alpha2-adrenoceptors in the canine isolated mesenteric veinQ24810915
Clonidine‐induced nitric oxide‐dependent vasorelaxation mediated by endothelial α2‐adrenoceptor activationQ28362700
Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivoQ28385491
Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cellsQ33884851
Clinical pharmacology, physiology and pathophysiology of superficial veins--2Q34346189
The mechanism of action of alpha 2-adrenoceptors in human isolated subcutaneous resistance arteriesQ35872705
Smooth muscle signalling pathways in health and diseaseQ37217197
Interpretation of tests of heterogeneity and bias in meta-analysisQ37329334
Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers.Q39861416
A new technique for recording compliance of human hand veinsQ42113407
Alpha 2-adrenergic receptors activate phospholipase C in renal epithelial cells.Q42519759
Alpha2-adrenergic receptor-induced vascular constriction in blacks and whitesQ44680942
Alpha 1A-adrenergic receptor polymorphism and vascular responseQ44922998
Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor responseQ46466416
Variation in the alpha2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo.Q46495946
Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjectsQ53514987
Subtypes of functional alpha1- and alpha2-adrenoceptorsQ53940936
Evaluation and application of the linear variable differential transformer technique for the assessment of human dorsal hand vein alpha-receptor activityQ70104661
Genetic aspects of variability in superficial vein responsiveness to norepinephrineQ70138742
Functional assessment of recombinant human alpha(2)-adrenoceptor subtypes with cytosensor microphysiometryQ73295609
Familial studies of heritability of α1-adrenergic receptor responsiveness in superficial veins*Q73794607
Signal transduction by protein kinase C in mammalian cellsQ77793400
Dorsal hand vein responses to the α₁-adrenoceptor agonist phenylephrine do not predict responses to the α₂-adrenoceptor agonist dexmedetomidineQ82831094
Calcium sensitization involved in dexmedetomidine-induced contraction of isolated rat aortaQ84810733
P433issue3
P921main subjectvasoconstrictionQ1067506
P304page(s)127-134
P577publication date2013-03-01
P1433published inPharmacogenetics and GenomicsQ10534561
P1476titleA polymorphism in the protein kinase C gene PRKCB is associated with α2-adrenoceptor-mediated vasoconstriction
P478volume23

Reverse relations

cites work (P2860)
Q49923465Evolving Mechanisms of Vascular Smooth Muscle Contraction Highlight Key Targets in Vascular Disease
Q39034887Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population
Q39291350Lack of Association Between Adrenoreceptor Genotype and the Vasoconstriction Response to Dexmedetomidine
Q47131231Protein Kinase C as Regulator of Vascular Smooth Muscle Function and Potential Target in Vascular Disorders

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