An epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohort

scientific article published on 24 October 2016

An epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohort is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1018700748
P356DOI10.1038/IJO.2016.184
P932PMC publication ID5209267
P698PubMed publication ID27773939

P50authorDale SandlerQ37376725
Jack A. TaylorQ42767532
Lauren WilsonQ57560641
Sophia HarlidQ63686907
P2093author name stringZ Xu
P2860cites workFrom obesity to diabetes and cancer: epidemiological links and role of therapiesQ26767027
In utero exposure to diethylstilbestrol and blood DNA methylation in women ages 40-59 years from the sister studyQ27312948
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DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?Q28729719
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DNA methylation arrays as surrogate measures of cell mixture distributionQ30530775
CpG sites associated with cigarette smoking: analysis of epigenome-wide data from the Sister StudyQ30794295
SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferationQ33958723
Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesityQ34080577
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.Q34329517
DNA methylation and body-mass index: a genome-wide analysisQ34410116
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Th1/Th17 plasticity is a marker of advanced β cell autoimmunity and impaired glucose tolerance in humansQ34756902
Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.Q35368842
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune responseQ35698515
Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumferenceQ35785914
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated lociQ35821136
Angiopoietin-like 4 (Angptl4) protein is a physiological mediator of intracellular lipolysis in murine adipocytesQ35868142
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese womenQ36035666
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Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα productionQ36395658
Decreased NK cells in patients with head and neck cancer determined in archival DNA.Q36405942
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control studyQ36496178
Epigenetic associations of type 2 diabetes and BMI in an Arab populationQ36513963
Attenuation of leptin and insulin signaling by SOCS proteinsQ36607776
Epigenome-wide association study of breast cancer using prospectively collected sister study samplesQ36843610
DNA methylation of lipid-related genes affects blood lipid levelsQ37234351
Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stressQ37362114
Epigenetics in adipose tissue, obesity, weight loss, and diabetesQ37446658
Genetic association analysis of 30 genes related to obesity in a European American populationQ37538462
Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairsQ37663303
Association of two polymorphisms within and near SOCS3 gene with obesity in three nationalities in Xinjiang province of ChinaQ37728771
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CD247, a novel T cell-derived diagnostic and prognostic biomarker for detecting disease progression and severity in patients with type 2 diabetes.Q39103543
Dietary patterns and weight change: 15-year longitudinal study in Australian adults.Q39965251
Genetic influences on the response of body fat and fat distribution to positive and negative energy balances in human identical twinsQ41481417
6C.05: STK39 AND WNK1 ARE POTENTIAL HYPERTENSION SUSCEPTIBILITY GENES IN THE BELHYPGEN COHORT.Q41647945
The effect of genetic variation of the retinoic acid receptor-related orphan receptor C gene on fatness in cattleQ41810533
Tumor necrosis factor-a augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradationQ43202271
A functional variant in the serine-threonine kinase coding gene is associated with hypertension: a case-control study in a Finnish population, the Tampere adult population cardiovascular risk studyQ45231823
DNA methylation map of human atherosclerosisQ46425260
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesityQ47314567
DNA methylation and gene expression patterns in adipose tissue differ significantly within young adult monozygotic BMI-discordant twin pairs.Q48114680
Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1.Q50718467
Expression of STK39 in peripheral blood of hypertension patients and the relationship between its genetic polymorphism and blood pressure.Q51292800
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.Q53802117
Xylosyltransferase I variants and their impact on abdominal aortic aneurysmsQ80758195
Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitusQ86244111
Pathogenic T helper type 17 cells contribute to type 1 diabetes independently of interleukin-22Q86547079
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDNA methylationQ874745
P304page(s)194-199
P577publication date2016-10-24
P1433published inInternational Journal of ObesityQ6051519
P1476titleAn epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohort
P478volume41

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cites work (P2860)
Q64977838An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.
Q40317688Association between DNA methylation at SOCS3 gene and body mass index might be due to familial confounding
Q90065794Body Mass Index Drives Changes in DNA Methylation: A Longitudinal Study
Q88601015Burly1 is a mouse QTL for lean body mass that maps to a 0.8-Mb region of chromosome 2
Q47661868Cell-type deconvolution from DNA methylation: a review of recent applications
Q41661037Critical Role of the Human ATP-Binding Cassette G1 Transporter in Cardiometabolic Diseases
Q55475236DNA methylation in human lipid metabolism and related diseases.
Q92451817DNA methylome profiling in identical twin pairs discordant for body mass index
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Q92058631Epigenetic mortality predictors and incidence of breast cancer
Q45073386Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond
Q41695097Epigenome-wide association studies for breast cancer risk and risk factors
Q64121823Epigenome-wide association study in peripheral white blood cells involving insulin resistance
Q92839240IL-8 -251A/T and +781C/T polymorphisms were associated with risk of breast cancer in a Chinese population
Q57305946Inference about causation between body mass index and DNA methylation in blood from a twin family study
Q47248476Novel associations between blood DNA methylation and body mass index in middle-aged and older adults
Q89767681Placental DNA methylation changes associated with maternal prepregnancy BMI and gestational weight gain
Q92263563Psychotropic drug-induced genetic-epigenetic modulation of CRTC1 gene is associated with early weight gain in a prospective study of psychiatric patients
Q92840662Reduced CRHR-2 in placental tissues is associated with the high DNA methylation of CRHR-2 promoter in idiopathic preterm birth
Q55690521Vitamin D, DNA methylation, and breast cancer.

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