Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond

scientific article published on 23 October 2017

Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JNUTBIO.2017.10.004
P932PMC publication ID5866737
P698PubMed publication ID29154162

P2093author name stringZhiyong Cheng
Fabio A Almeida
Louise Zheng
P2860cites workHypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunctionQ37039788
Blood lipids influence DNA methylation in circulating cellsQ37040432
DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes riskQ37082673
Recent developments on the role of epigenetics in obesity and metabolic diseaseQ37084777
FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytesQ37143203
DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistanceQ37230787
Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesityQ37308106
Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish menQ37350189
Muscle Contraction Induces Acute Hydroxymethylation of the Exercise-Responsive Gene Nr4a3.Q37528467
An epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohortQ37553115
Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesityQ37571427
Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies.Q37639793
DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients.Q37649597
Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expressionQ37671785
The Akt-SREBP nexus: cell signaling meets lipid metabolism.Q37684518
Cross-tissue comparisons of leptin and adiponectin: DNA methylation profilesQ37692537
ATP-binding cassette proteins involved in glucose and lipid homeostasisQ37749201
The role of mitochondria in insulin resistance and type 2 diabetes mellitusQ37930956
36 h fasting of young men influences adipose tissue DNA methylation of LEP and ADIPOQ in a birth weight-dependent mannerQ33587463
TET enzymes, TDG and the dynamics of DNA demethylation.Q33715010
Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic isletsQ33787509
The epigenetic signature of systemic insulin resistance in obese womenQ33895274
Regulation of insulin secretion: role of mitochondrial signallingQ33914248
Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesityQ33965673
Open chromatin profiling in mice livers reveals unique chromatin variations induced by high fat dietQ34140973
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass indexQ34211781
Global DNA methylation is associated with insulin resistance: a monozygotic twin studyQ34243835
Acute exercise remodels promoter methylation in human skeletal muscle.Q34260142
Epigenome-wide association study of fasting blood lipids in the Genetics of Lipid-lowering Drugs and Diet Network studyQ34406002
DNA methylation and body-mass index: a genome-wide analysisQ34410116
Targeting mitochondrial alterations to prevent type 2 diabetes--evidence from studies of dietary redox-active compoundsQ34412057
Obesity accelerates epigenetic aging of human liverQ34441968
Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetesQ34516412
An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twinsQ34833062
An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss.Q34994872
Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretionQ35112943
Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed miceQ35227126
Dietary modifications, weight loss, and changes in metabolic markers affect global DNA methylation in Hispanic, African American, and Afro-Caribbean breast cancer survivorsQ35239448
Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.Q35368842
Platelet mitochondrial DNA methylation: a potential new marker of cardiovascular diseaseQ35505135
Formation and activation of thermogenic fat.Q35561446
Epigenetic patterns in successful weight loss maintainers: a pilot studyQ35577833
Transcriptional control and hormonal response of thermogenic fat.Q35589477
Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and womenQ35619519
Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolismQ35641736
Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humansQ35776712
Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumferenceQ35785914
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated lociQ35821136
Energy balance and its components: implications for body weight regulationQ35826443
Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistanceQ35863452
Tissue specific DNA methylation of CpG islands in normal human adult somatic tissues distinguishes neural from non-neural tissues.Q35878561
HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT.Q35881871
Lipid-induced mitochondrial stress and insulin action in muscleQ35947486
Novel epigenetic determinants of type 2 diabetes in Mexican-American familiesQ35999273
The updated biology of hypoxia-inducible factorQ36001994
The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese womenQ36035666
Cardiometabolic Risk Factor Changes Observed in Diabetes Prevention Programs in US Settings: A Systematic Review and Meta-analysisQ36086147
Adiposity is associated with DNA methylation profile in adipose tissueQ36107643
Targeting FoxO1 with AS1842856 suppresses adipogenesisQ36183882
Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET ProteinsQ36194904
Mitochondrial dysfunction in white adipose tissueQ36198938
An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after trainingQ36211250
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization ApproachQ36251303
An Interactive Computer Session to Initiate Physical Activity in Sedentary Cardiac Patients: Randomized Controlled TrialQ36273084
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancersQ36280667
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetesQ36410632
Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate LevelsQ36433576
Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American familiesQ36485619
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control studyQ36496178
Epigenetic associations of type 2 diabetes and BMI in an Arab populationQ36513963
High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring.Q36628050
DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework.Q36820782
Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhoodQ36833354
Associations between whole peripheral blood fatty acids and DNA methylation in humansQ36903216
Arachidonic and oleic acid exert distinct effects on the DNA methylome.Q36956881
Mitochondrial Epigenetic Changes Link to Increased Diabetes Risk and Early-Stage Prediabetes IndicatorQ36958809
PPARGC1α gene DNA methylation variations in human placenta mediate the link between maternal hyperglycemia and leptin levels in newbornsQ37031287
SREBPs: metabolic integrators in physiology and metabolismQ37966406
Inflammation and lipid signaling in the etiology of insulin resistanceQ38007632
Novel links between HIFs, type 2 diabetes, and metabolic syndromeQ38024200
Epigenetic flexibility in metabolic regulation: disease cause and prevention?Q38070622
Adipose tissue browning and metabolic healthQ38154504
Prevention of type 2 diabetes; a systematic review and meta-analysis of different intervention strategiesQ38183131
Mitochondrial alteration in type 2 diabetes and obesity: an epigenetic link.Q38189524
Epigenetics and human obesity.Q38190867
Epigenetic adaptation to regular exercise in humansQ38196210
Mitochondrial function/dysfunction in white adipose tissueQ38240308
Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes.Q38264613
Epigenetics and metabolism.Q38353919
Genetic alterations of DNA methylation machinery in human diseasesQ38459846
DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetesQ38528435
Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patientsQ38668121
Lateral Thinking: How Histone Modifications Regulate Gene ExpressionQ38679432
Hepatic DPP4 DNA Methylation Associates With Fatty Liver.Q38725135
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposityQ38779718
Environmental Health and Long Non-coding RNAsQ38846322
The role of diet and exercise in the transgenerational epigenetic landscape of T2DM.Q38867791
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetesQ38888130
Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue: a randomized controlled trial.Q38919684
A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiationQ38960282
Mitochondrial Adaptation in Nonalcoholic Fatty Liver Disease: Novel Mechanisms and Treatment StrategiesQ39041789
Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liverQ39136510
Mitochondrial homeostasis in adipose tissue remodeling.Q39155209
Hypoxia-inducible factor (HIF)-3alpha is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2.Q39711333
Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans.Q40210114
Fetal Hyperglycemia Changes Human Preadipocyte Function in Adult LifeQ40330806
DNA 5-hydroxymethylation in human adipose tissue differs between subcutaneous and visceral adipose tissue depotsQ40486688
Epigenome-wide association study identifies TXNIP gene associated with type 2 diabetes mellitus and sustained hyperglycemiaQ41068625
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell functionQ41316289
PPAR-gamma: adipogenic regulator and thiazolidinedione receptorQ41755813
Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetesQ42216029
Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor γ coactivator 1α promoter.Q42870876
Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent mannerQ43089854
Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypesQ43111069
Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density.Q43282402
Mitochondria and metabolic homeostasisQ43741919
Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver diseaseQ43761846
Differential DNA methylation patterns between high and low responders to a weight loss intervention in overweight or obese adolescents: the EVASYON studyQ44757043
A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissueQ21563356
Genetic studies of body mass index yield new insights for obesity biologyQ22305005
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretionQ24650896
MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeuticsQ26796668
Mitochondrial fatty acid oxidation in obesityQ26820838
DNA methylation in mammalsQ26852141
Mechanisms and metabolic implications of regional differences among fat depotsQ27004113
Genetic and epigenetic control of metabolic healthQ27026287
Chromatin Modifications Associated With Diabetes and ObesityQ27028212
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
The cell biology of fat expansionQ28084054
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose toleranceQ28186874
Effectiveness of a worksite-based weight loss randomized controlled trial: the worksite studyQ28390945
Functions of DNA methylation: islands, start sites, gene bodies and beyondQ29547260
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiationQ29617398
Mitochondrial dysfunction and type 2 diabetesQ29617913
Adipocytokines: mediators linking adipose tissue, inflammation and immunityQ29619393
Mechanisms for insulin resistance: common threads and missing linksQ29620447
Exercise prevents maternal high-fat diet-induced hypermethylation of the Pgc-1α gene and age-dependent metabolic dysfunction in the offspringQ30457309
Effect of regression from prediabetes to normal glucose regulation on long-term reduction in diabetes risk: results from the Diabetes Prevention Program Outcomes StudyQ30533186
Isolation of Mouse Stromal Vascular Cells for Monolayer CultureQ45053644
Leptin and TNF-alpha promoter methylation levels measured by MSP could predict the response to a low-calorie diet.Q45123069
Weight loss after gastric bypass surgery in human obesity remodels promoter methylationQ45130608
Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia responseQ45829201
Methylation levels of the SCD1 gene promoter and LINE-1 repeat region are associated with weight change: an intervention studyQ47173375
PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects--impact of 5 days of high-fat overfeedingQ47198497
DNA Methylation and Hydroxymethylation Levels in Relation to Two Weight Loss Strategies: Energy-Restricted Diet or Bariatric Surgery.Q47373483
Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes PathogenesisQ48095510
DNA methylation and gene expression patterns in adipose tissue differ significantly within young adult monozygotic BMI-discordant twin pairs.Q48114680
5-hydroxymethylcytosine in DNA repair: A new player or a red herring?Q48342500
Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeedingQ48884219
Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle.Q50992296
PGC1α promoter methylation in blood at 5-7 years predicts adiposity from 9 to 14 years (EarlyBird 50).Q51102461
Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action.Q51271391
Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.Q53802117
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in bloodQ57736683
Insulin Resistance in the Defense against ObesityQ58197108
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genesQ60056998
DNA methylation of leptin and adiponectin promoters in children is reduced by the combined presence of obesity and insulin resistance.Q64923100
Energy balance and obesityQ84510561
P921main subjectnutrition disorderQ1361144
P304page(s)1-10
P577publication date2017-10-23
P1433published inJournal of Nutritional BiochemistryQ15716705
P1476titleEpigenetic reprogramming in metabolic disorders: nutritional factors and beyond
P478volume54

Reverse relations

cites work (P2860)
Q92537636A Maternal High-Fat Diet Induces DNA Methylation Changes That Contribute to Glucose Intolerance in Offspring
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