| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Salvatore Cuzzocrea | Q56957753 |
| P2093 | author name string | Emanuela Esposito | |
| P2860 | cites work | Nitric oxide and peroxynitrite in health and disease | Q24645400 |
| The endocannabinoid system as an emerging target of pharmacotherapy | Q24648473 | ||
| Adenosine receptors: therapeutic aspects for inflammatory and immune diseases | Q24651475 | ||
| Nitric oxide and superoxide in inflammation and immune regulation. | Q27863326 | ||
| Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein) | Q28252462 | ||
| Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion | Q28345800 | ||
| Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403 | Q28349680 | ||
| Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury | Q28511628 | ||
| Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice | Q28592978 | ||
| Peroxynitrite reactions and formation in mitochondria | Q28610681 | ||
| The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide | Q28611706 | ||
| Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide | Q29547245 | ||
| Superoxide radical and superoxide dismutases | Q29614204 | ||
| Peroxynitrite: biochemistry, pathophysiology and development of therapeutics | Q29615424 | ||
| Gene therapy with extracellular superoxide dismutase protects conscious rabbits against myocardial infarction | Q30417743 | ||
| Effects of the superoxide radical scavenger superoxide dismutase, and of the hydroxyl radical scavenger mannitol, on reperfusion injury in isolated rabbit hearts | Q30834859 | ||
| Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase | Q30994005 | ||
| Peroxynitrite induced nitration and inactivation of myofibrillar creatine kinase in experimental heart failure | Q32077774 | ||
| Cu/Zn-superoxide dismutase gene attenuates ischemia-reperfusion injury in the rat kidney. | Q43812816 | ||
| Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis | Q43816241 | ||
| Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic | Q43837387 | ||
| Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor | Q44087051 | ||
| A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs | Q44194513 | ||
| Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines | Q44232110 | ||
| Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction | Q44319426 | ||
| Hemodynamic determinants of mortality in human septic shock | Q44478113 | ||
| The adrenochrome pathway. A potential catabolic route for adrenaline metabolism in inflammatory disease | Q44784720 | ||
| Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats | Q44933518 | ||
| Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid. A novel mechanism for nitric oxide-mediated protein modification | Q45183098 | ||
| Reactivity of 2',7'-dichlorodihydrofluorescein and dihydrorhodamine 123 and their oxidized forms toward carbonate, nitrogen dioxide, and hydroxyl radicals | Q45193493 | ||
| Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity | Q46070812 | ||
| Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury | Q46234801 | ||
| Protective mechanisms of a metalloporphyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants | Q46398346 | ||
| Characterization of the cytoprotective action of peroxynitrite decomposition catalysts | Q47982104 | ||
| Selective inhibition of the activity of inducible nitric oxide synthase prevents the circulatory failure, but not the organ injury/dysfunction, caused by endotoxin | Q48001412 | ||
| Metalloporphyrins are potent inhibitors of lipid peroxidation | Q48226744 | ||
| Manganese superoxide dismutase overexpression attenuates MPTP toxicity. | Q48332030 | ||
| Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury | Q48562268 | ||
| Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both | Q50126739 | ||
| Enhanced generation of leukotriene B4 and superoxide radical from calcium ionophore (A23187) stimulated human neutrophils after priming with interferon-alpha. | Q50507652 | ||
| Monocyte stimulation by reactive oxygen species: role of superoxide and intracellular Ca2+. | Q50515758 | ||
| Reactive oxygen species produced by liver mitochondria of rats in sepsis. | Q52540249 | ||
| Low doses of superoxide dismutase and a stable prostacyclin analogue protect in myocardial ischemia and reperfusion | Q54068458 | ||
| A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock. | Q54461995 | ||
| Mast cells as a source of superoxide anions and nitric oxide-like factor: relevance to histamine release. | Q54704233 | ||
| EUK-8 a synthetic catalytic scavenger of reactive oxygen species protects isolated iron-overloaded rat heart from functional and structural damage induced by ischemia/reperfusion. | Q55066740 | ||
| Lecithinized Cu, Zn-superoxide dismutase limits the infarct size following ischemia-reperfusion injury in rat hearts in vivo | Q95721646 | ||
| Metalloporphyrin class of therapeutic catalytic antioxidants | Q33720584 | ||
| Peroxynitrite scavenging by metalloporphyrins and thiolates | Q33991773 | ||
| Free radical production and angiotensin | Q34028489 | ||
| Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia | Q34111409 | ||
| Inflammatory roles of P-selectin | Q34169805 | ||
| Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants. | Q34284896 | ||
| The signaling pathways induced by neutrophil-endothelial cell adhesion | Q34611195 | ||
| Superoxide, superoxide dismutase and ischemic injury | Q34757538 | ||
| Reactive oxygen species and endothelial activation | Q34757570 | ||
| The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock | Q35025367 | ||
| Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure | Q35027134 | ||
| Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo | Q35044475 | ||
| Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine | Q35052402 | ||
| Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock | Q35214654 | ||
| The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase | Q35873190 | ||
| Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. | Q35913809 | ||
| Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology | Q35933719 | ||
| Endothelial dysfunction and reactive oxygen species production in ischemia/reperfusion and nitrate tolerance | Q36002488 | ||
| Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst | Q36087920 | ||
| NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease | Q36110357 | ||
| Nitrosative stress and pharmacological modulation of heart failure | Q36145124 | ||
| Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells | Q36220524 | ||
| Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide | Q36376397 | ||
| Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects | Q36380660 | ||
| Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning | Q36416372 | ||
| Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo | Q36431848 | ||
| Nitric oxide activates cyclooxygenase enzymes. | Q36457941 | ||
| Peroxynitrite activates ERK via Raf-1 and MEK, independently from EGF receptor and p21Ras in H9C2 cardiomyocytes | Q36478588 | ||
| Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils | Q36529236 | ||
| Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils | Q36532906 | ||
| Possible therapies of septic shock: based on animal studies and clinical trials | Q36612093 | ||
| Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches | Q36665320 | ||
| Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease | Q36734840 | ||
| Sepsis and the heart. | Q36910137 | ||
| The tragedy of TRIUMPH for nitric oxide synthesis inhibition in cardiogenic shock: where do we go from here? | Q36978197 | ||
| Oxidative inactivation of key mitochondrial proteins leads to dysfunction and injury in hepatic ischemia reperfusion | Q37002521 | ||
| The chemistry of peroxynitrite: implications for biological activity | Q37073008 | ||
| Sepsis: time to reconsider the concept | Q37145786 | ||
| Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite | Q37370840 | ||
| Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia | Q37681145 | ||
| Peroxynitrite is an essential component of cytokines production mechanism in human monocytes through modulation of nuclear factor-kappa B DNA binding activity | Q38294793 | ||
| Oxidative stress induces NF kappa B DNA binding and inducible NOS mRNA in human epithelial cells. | Q38309878 | ||
| Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice. | Q38547659 | ||
| Participation of superoxide anions at the prostaglandin phase of carrageenan foot-oedema | Q39106321 | ||
| Oxygen-derived free radicals in postischemic tissue injury | Q39492590 | ||
| Superoxide dismutase for therapeutic use: clinical experience, dead ends and hopes | Q39564943 | ||
| Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones | Q39615110 | ||
| Neutrophil-mediated vascular injury | Q39657198 | ||
| Leukocyte-endothelial interactions | Q39845907 | ||
| Treatment of circulatory shock. Use of sympathomimetic and related vasoactive agents | Q40309727 | ||
| The Role of the l-arginine: Nitric Oxide Pathway in Circulatory Shock | Q40392297 | ||
| The formation of peroxynitrite in vivo from nitric oxide and superoxide | Q40513159 | ||
| Pathological implications of nitric oxide, superoxide and peroxynitrite formation | Q40857191 | ||
| Free radicals as mediators of tissue injury and disease | Q40895574 | ||
| Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock | Q40908234 | ||
| Reactions between nitric oxide, superoxide, and peroxynitrite: footprints of peroxynitrite in vivo | Q40945747 | ||
| Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface | Q41022057 | ||
| Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury. | Q41128813 | ||
| Oxidative damage and tyrosine nitration from peroxynitrite | Q41129375 | ||
| The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. | Q41151395 | ||
| Neutrophil accumulation in ischemic canine myocardium. Insights into time course, distribution, and mechanism of localization during early reperfusion | Q41188965 | ||
| Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy | Q41191851 | ||
| Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger | Q41226484 | ||
| Suppression of fibrosarcoma metastasis by elevated expression of manganese superoxide dismutase | Q41448596 | ||
| Superoxide: a two-edged sword | Q41547134 | ||
| Prevention of reperfusion-induced, free radical-mediated acute endothelial injury by superoxide dismutase as an effective tool to delay/prevent chronic renal allograft failure: a review | Q41589339 | ||
| SOD2: a new type of tumor-suppressor gene? | Q41623526 | ||
| Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan-induced shock | Q41942222 | ||
| Direct measurement of myocardial free radical generation in an in vivo model: effects of postischemic reperfusion and treatment with human recombinant superoxide dismutase | Q41958075 | ||
| Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin-induced intestinal damage | Q41988922 | ||
| Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions | Q42101310 | ||
| Intercellular adhesion molecule-1 gene expression in human endothelial cells. Differential regulation by tumor necrosis factor-alpha and phorbol myristate acetate | Q42453127 | ||
| Myocardial cell damage and cardiovascular changes due to i.v. infusion of adrenochrome in rats. | Q42613776 | ||
| Effect of norepinephrine on the outcome of septic shock | Q42632719 | ||
| Computer-aided design (CAD) of Mn(II) complexes: superoxide dismutase mimetics with catalytic activity exceeding the native enzyme | Q43582097 | ||
| Detoxification of reactive oxygen species by a nonpeptidyl mimic of superoxide dismutase cures acetaminophen-induced acute liver failure in the mouse | Q43601194 | ||
| Mechanisms of peroxynitrite decomposition catalyzed by FeTMPS, a bioactive sulfonated iron porphyrin | Q43616050 | ||
| Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation | Q43669469 | ||
| The superoxide dismutase mimetic MnTBAP prevents Fas-induced acute liver failure in the mouse | Q43812746 | ||
| Microcirculatory approach to the treatment of circulatory shock with a new analog of vasopressin, (2-phenylalanine, 8-ornithine)vasopressin | Q67741818 | ||
| Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide | Q67913773 | ||
| American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis | Q68141412 | ||
| Direct and respiratory chain-mediated redox cycling of adrenochrome | Q68457352 | ||
| Ischemia-reperfusion injury and free radical involvement in gastric mucosal disorders | Q68609828 | ||
| Superoxide dismutase and catalase in skin flaps during venous occlusion and reperfusion | Q68871412 | ||
| Superoxide dismutase enhances recovery following myocardial ischemia | Q70101971 | ||
| Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies | Q71069881 | ||
| EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine | Q71513307 | ||
| Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema | Q71546642 | ||
| Comparison of the cardiovascular effects of two novel superoxide dismutase mimetics, SC-55858 and SC-54417, in conscious dogs | Q71546679 | ||
| Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury | Q71736276 | ||
| Measurement of nitric oxide and peroxynitrite generation in the postischemic heart. Evidence for peroxynitrite-mediated reperfusion injury | Q71763431 | ||
| Peroxynitrite causes DNA damage and oxidation of thiols in rat thymocytes [corrected] | Q71778936 | ||
| Free radicals in reperfusion-induced arrhythmias: study with EUK 8, a novel nonprotein catalytic antioxidant | Q71820907 | ||
| EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage | Q71907872 | ||
| Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide | Q72035255 | ||
| Superoxide dismutase mimetics inhibit neutrophil-mediated human aortic endothelial cell injury in vitro | Q72068555 | ||
| Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo | Q72196565 | ||
| Abnormal vascular tone, defective oxygen transport and myocardial failure in human septic shock | Q72212424 | ||
| Anti-inflammatory effects of recombinant human manganese superoxide dismutase on adjuvant arthritis in rats | Q72417268 | ||
| Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion | Q72460791 | ||
| Intercellular adhesion molecule 1 (ICAM-1) expression and its role in neutrophil-induced ischemia-reperfusion injury in rat liver | Q72615916 | ||
| A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats | Q73066471 | ||
| Overexpression of CuZnSOD in coronary vascular cells attenuates myocardial ischemia/reperfusion injury | Q73082159 | ||
| Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: a prospective, randomized study | Q73182846 | ||
| Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites | Q73317141 | ||
| Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia | Q73321077 | ||
| Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite | Q73425760 | ||
| Clastogenic Factors In Plasma Of HIV-1 Infected Patients Activate HIV-1 Replication In Vitro: Inhibition By Superoxide Dismutase | Q73494718 | ||
| Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion | Q73842160 | ||
| Dual role of nitric oxide in myocardial ischemia-reperfusion | Q73918640 | ||
| Superoxide dismutase in development of obliterative bronchiolitis | Q74019527 | ||
| Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure | Q74114005 | ||
| Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock | Q74624318 | ||
| Computer-Aided Design (CAD) of Synzymes: Use of Molecular Mechanics (MM) for the Rational Design of Superoxide Dismutase Mimics | Q74833386 | ||
| Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion | Q77089411 | ||
| Superoxide dismutase mimetic with catalase activity, EUK-134, attenuates the multiple organ injury and dysfunction caused by endotoxin in the rat | Q77505743 | ||
| Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites:implications in inflammation | Q78020191 | ||
| Effect of reactive oxygen metabolites on endothelial permeability: role of nitric oxide and iron | Q78183953 | ||
| Oxidative stress in cardiovascular disease: a new avenue toward future therapeutic approaches | Q80551173 | ||
| Beneficial effects of FeTSPP, a peroxynitrite decomposition catalyst, in a mouse model of spinal cord injury | Q80703689 | ||
| Therapeutic manipulations of peroxynitrite | Q81192523 | ||
| Chronic obstructive pulmonary disease | Q93936786 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 494-508 | |
| P577 | publication date | 2009-06-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Role of nitroso radicals as drug targets in circulatory shock | |
| P478 | volume | 157 |
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| Q37174392 | NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite |
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