| scholarly article | Q13442814 |
| P50 | author | Maxwell Afari Gyamfi | Q110534975 |
| P2093 | author name string | Frank J Gonzalez | |
| John M Cullen | |||
| Ricardo M Richardson | |||
| Emmanuel M Awumey | |||
| Krisstonia Spruiell | |||
| P2860 | cites work | SXR, a novel steroid and xenobiotic-sensing nuclear receptor | Q22003995 |
| Identification of a nuclear receptor for bile acids | Q22010058 | ||
| The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions | Q24310512 | ||
| Identification of a novel gene encoding an insulin-responsive glucose transporter protein | Q24338976 | ||
| Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans | Q24605470 | ||
| Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity | Q24617406 | ||
| The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity | Q24630723 | ||
| Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction | Q24646162 | ||
| Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators | Q24652367 | ||
| Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase | Q28215845 | ||
| The mechanisms of action of PPARs | Q28216953 | ||
| A role for brown adipose tissue in diet-induced thermogenesis | Q28253495 | ||
| An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway | Q28263744 | ||
| Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene | Q28289436 | ||
| The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution | Q28378587 | ||
| Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis | Q28507525 | ||
| Liver X receptors regulate de novo lipogenesis in a tissue-specific manner in C57BL/6 female mice. | Q51471193 | ||
| Hepatic and extrahepatic responses to insulin in NIDDM and nondiabetic humans. Assessment in absence of artifact introduced by tritiated nonglucose contaminants. | Q54331251 | ||
| The role of retinoid X receptor alpha in regulating alcohol metabolism. | Q54593072 | ||
| Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions | Q57249776 | ||
| Role of leptin in fat regulation | Q59062544 | ||
| Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice | Q59328728 | ||
| Dietary calcium attenuation of body fat gain during high-fat feeding in mice | Q59504002 | ||
| Hepatic mitochondrial DNA deletion in alcoholics: association with microvesicular steatosis | Q72371132 | ||
| Obesity as an adaptation to a high-fat diet: evidence from a cross-sectional study | Q72890203 | ||
| Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in | Q73218533 | ||
| Low plasma leptin in response to dietary fat in diabetes- and obesity-prone mice | Q73674120 | ||
| Diagnosis and interpretation of steatosis and steatohepatitis | Q77654767 | ||
| Peroxisomal and mitochondrial fatty acid beta-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor alpha and peroxisomal fatty acyl-CoA oxidase. Genotype correlation with fatty liver phenotype | Q77926979 | ||
| Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation | Q78025580 | ||
| Regenerative capacity differs between micro- and macrovesicular hepatic steatosis | Q81297061 | ||
| AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism | Q29617261 | ||
| Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity | Q29619156 | ||
| Nuclear receptors and lipid physiology: opening the X-files | Q29619362 | ||
| Carnitine acyltransferases: functional significance of subcellular distribution and membrane topology | Q33832294 | ||
| Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites | Q33837172 | ||
| A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway | Q33945905 | ||
| Activation of pregnane X receptor by pregnenolone 16 α-carbonitrile prevents high-fat diet-induced obesity in AKR/J mice | Q34313944 | ||
| Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. | Q34327135 | ||
| Pregnane X Receptor and Constitutive Androstane Receptor at the Crossroads of Drug Metabolism and Energy Metabolism | Q34359458 | ||
| An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. | Q34732527 | ||
| Bile acid regulation of gene expression: roles of nuclear hormone receptors. | Q34803254 | ||
| Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis | Q35995063 | ||
| The genetics of human obesity | Q36036700 | ||
| Impaired glucose tolerance: is there a case for pharmacologic intervention? | Q36084150 | ||
| Chronic exposure to rifaximin causes hepatic steatosis in pregnane X receptor-humanized mice | Q36379917 | ||
| Fat in the liver: diagnosis and characterization | Q36396122 | ||
| Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver | Q36482946 | ||
| The role of AMP kinase in diabetes | Q36819043 | ||
| PXR ablation alleviates diet-induced and genetic obesity and insulin resistance in mice | Q36867493 | ||
| Nonalcoholic fatty liver disease: pathogenesis and potential for nuclear receptors as therapeutic targets | Q37029290 | ||
| AMP activated protein kinase: a next generation target for total metabolic control. | Q37030884 | ||
| Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice | Q37130242 | ||
| New developments in adipogenesis | Q37408916 | ||
| Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes | Q37493137 | ||
| Relatively low plasma leptin concentrations precede weight gain in Pima Indians | Q38348967 | ||
| Agreement between laboratory results and on-site pathology testing using Bayer DCA2000+ and Cholestech LDX point-of-care methods in remote Australian Aboriginal communities | Q39740996 | ||
| Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene. | Q40106533 | ||
| Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity | Q40379756 | ||
| Humanized xenobiotic response in mice expressing nuclear receptor SXR. | Q41753938 | ||
| Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesis | Q42488444 | ||
| The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease | Q43235201 | ||
| Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR. | Q43683607 | ||
| Relationship between visceral adiposity and intramyocellular lipid content in two rat models of insulin resistance | Q45029538 | ||
| Insulin induces the translocation of GLUT4 from a unique intracellular organelle to transverse tubules in rat skeletal muscle | Q46374050 | ||
| Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes | Q46747714 | ||
| NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet. | Q46748175 | ||
| Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression | Q46813713 | ||
| Hepatocyte retinoid X receptor alpha-dependent regulation of lipid homeostasis and inflammatory cytokine expression contributes to alcohol-induced liver injury | Q46920813 | ||
| Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance | Q47886909 | ||
| The PREgnane X receptor gene-humanized mouse: a model for investigating drug-drug interactions mediated by cytochromes P450 3A. | Q48645885 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | obesity | Q12174 |
| glycobiology | Q899224 | ||
| glucose | Q37525 | ||
| P1104 | number of pages | 18 | |
| P304 | page(s) | 3244-3261 | |
| P577 | publication date | 2013-12-20 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Role of pregnane X receptor in obesity and glucose homeostasis in male mice | |
| P478 | volume | 289 |
| Q56534254 | A selective gut bacterial bile salt hydrolase alters host metabolism |
| Q35920926 | Aryl hydrocarbon receptor deficiency protects mice from diet-induced adiposity and metabolic disorders through increased energy expenditure |
| Q26822721 | Biology of PXR: role in drug-hormone interactions |
| Q38648917 | Dietary regulation of adiponectin by direct and indirect lipid activators of nuclear hormone receptors |
| Q47100840 | Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a pregnane X receptor-centric view |
| Q36380561 | Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin allocation by dietary lipids and environmental toxicants |
| Q39324093 | Functions of pregnane X receptor in self-detoxification. |
| Q88605029 | High fat diet induced obesity is mitigated in Cyp3a-null female mice |
| Q36244500 | IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity. |
| Q33631366 | Irisin Is Regulated by CAR in Liver and Is a Mediator of Hepatic Glucose and Lipid Metabolism |
| Q90381179 | Marine Ligands of the Pregnane X Receptor (PXR): An Overview |
| Q28071265 | Molecular Pathogenesis of NASH |
| Q30251861 | Novel functions of PXR in cardiometabolic disease |
| Q38768048 | Nuclear receptors and nonalcoholic fatty liver disease |
| Q38378655 | Nuclear receptors in vascular biology. |
| Q50117089 | PXR: More Than Just a Master Xenobiotic Receptor |
| Q36573579 | Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis. |
| Q37243869 | Pregnane X Receptor and Cancer: Context-Specificity is Key. |
| Q35962050 | Pregnane X Receptor-Humanized Mice Recapitulate Gender Differences in Ethanol Metabolism but Not Hepatotoxicity |
| Q53023338 | Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms. |
| Q47419101 | Pregnane X receptor promotes ethanol-induced hepatosteatosis in mice |
| Q91483621 | Rifampicin Alters Metformin Plasma Exposure but Not Blood Glucose Levels in Diabetic Tuberculosis Patients |
| Q33756030 | Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice |
| Q38678741 | Targeting nuclear receptors for the treatment of fatty liver disease |
| Q90449180 | Transcriptomic responses of hypothalamus to acute exercise in type 2 diabetic Goto-Kakizaki rats |
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