scholarly article | Q13442814 |
P356 | DOI | 10.1038/SJ.IJO.0801209 |
P698 | PubMed publication ID | 10849588 |
P50 | author | Xu-Feng Huang | Q30511302 |
P2093 | author name string | L H Storlien | |
S Lin | |||
T C Thomas | |||
P2860 | cites work | Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity | Q22241899 |
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Weight-reducing effects of the plasma protein encoded by the obese gene | Q29617934 | ||
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Diet-induced obese mice develop peripheral, but not central, resistance to leptin | Q37362925 | ||
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus | Q38342613 | ||
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Current views on obesity | Q40986157 | ||
The pharmacologic approach to the treatment of obesity | Q41518654 | ||
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Inhibition of food response to intracerebroventricular injection of leptin is attenuated in rats with diet-induced obesity | Q48601029 | ||
Adipose tissue leptin production and plasma leptin kinetics in humans | Q71150204 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | obesity | Q12174 |
P304 | page(s) | 639-646 | |
P577 | publication date | 2000-05-01 | |
P1433 | published in | International Journal of Obesity | Q6051519 |
P1476 | title | Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice | |
P478 | volume | 24 |
Q40618191 | A Licorice Ethanolic Extract with Peroxisome Proliferator-Activated Receptor-γ Ligand-Binding Activity Affects Diabetes in KK-Ay Mice, Abdominal Obesity in Diet-Induced Obese C57BL Mice and Hypertension in Spontaneously Hypertensive Rats |
Q37478197 | A Mouse Model of Diet-Induced Obesity Resembling Most Features of Human Metabolic Syndrome |
Q46407015 | A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse |
Q36298292 | A camera-phone based study reveals erratic eating pattern and disrupted daily eating-fasting cycle among adults in India. |
Q42015971 | A high salt diet inhibits obesity and delays puberty in the female rat. |
Q36815297 | A high-fat diet decreases AMPK activity in multiple tissues in the absence of hyperglycemia or systemic inflammation in rats |
Q39473547 | A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice |
Q37086232 | A high-fat diet supplemented with fish oil improves metabolic features associated with type 2 diabetes |
Q37462425 | A nutrigenomic framework to identify time-resolving responses of hepatic genes in diet-induced obese mice |
Q38755564 | APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion |
Q33965790 | AT1 receptor blockade alters nutritional and biometric development in obesity-resistant and obesity-prone rats submitted to a high fat diet |
Q30487953 | Accelerated recovery from acute hypoxia in obese mice is due to obesity-associated up-regulation of interleukin-1 receptor antagonist |
Q38721779 | Access to nicotine in drinking water reduces weight gain without changing caloric intake on high fat diet in male C57BL/6J mice |
Q46888836 | Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice |
Q34779049 | Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease. |
Q26800025 | Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity |
Q58778932 | Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet |
Q33513320 | Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure |
Q52144834 | Analysis of neuron-astrocyte metabolic cooperation in the brain of db/db mice with cognitive decline using 13C NMR spectroscopy. |
Q84583848 | Anorexic vs. metabolic effects of central leptin infusion in rats of various ages and nutritional states |
Q36924205 | Antcin K, a Triterpenoid Compound from Antrodia camphorata, Displays Antidiabetic and Antihyperlipidemic Effects via Glucose Transporter 4 and AMP-Activated Protein Kinase Phosphorylation in Muscles |
Q34381186 | Anti-diabetic effect of balanced deep-sea water and its mode of action in high-fat diet induced diabetic mice |
Q33931073 | Anti-obesity effect of an isoflavone fatty acid ester on obese mice induced by high fat diet and its potential mechanism |
Q42376281 | Anti-obesity effect of robusta fermented with Leuconostoc mesenteroides in high-fat diet-induced obese mice |
Q37440329 | Anti-obesity effects of traditional and standardized meju in high-fat diet-induced obese C57BL/6J mice |
Q73293527 | Antiobesity and antidiabetic effects of brain-derived neurotrophic factor in rodent models of leptin resistance |
Q87184652 | Beneficial effects of hydro-alcoholic extract of Caralluma fimbriata against high-fat diet-induced insulin resistance and oxidative stress in Wistar male rats |
Q57255670 | Cardiovascular Actions of Leptin in the Subfornical Organ are Abolished by Diet-Induced Obesity |
Q36080486 | Catestatin (chromogranin A(352-372)) and novel effects on mobilization of fat from adipose tissue through regulation of adrenergic and leptin signaling |
Q39206330 | Central glucagon-like peptide 1 receptor-induced anorexia requires glucose metabolism-mediated suppression of AMPK and is impaired by central fructose |
Q50440819 | Changes in gene expression and sensitivity of cocaine reward produced by a continuous fat diet. |
Q89835099 | Characterizing the Retinal Phenotype in the High-Fat Diet and Western Diet Mouse Models of Prediabetes |
Q64107015 | Chronic High-Fat Diet Exacerbates Sexually Dimorphic Pomctm1/tm1 Mouse Obesity |
Q43966428 | Chronic ethanol consumption increases plasma leptin levels and alters leptin receptors in the hypothalamus and the perigonadal fat of C57BL/6 mice |
Q37483110 | Chrysophanic Acid Suppresses Adipogenesis and Induces Thermogenesis by Activating AMP-Activated Protein Kinase Alpha In vivo and In vitro |
Q90316983 | Circulating leptin levels are associated with adiposity in survivors of childhood brain tumors |
Q58789162 | Cold exposure promotes obesity and impairs glucose homeostasis in mice subjected to a high‑fat diet |
Q46288245 | Combination of β-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet |
Q58760731 | Cyclin-dependent kinase 4 is a preclinical target for diet-induced obesity |
Q48097245 | Cytokine-mediated inflammation mediates painful neuropathy from metabolic syndrome |
Q46811140 | Decreased intestinal nutrient response in diet-induced obese rats: role of gut peptides and nutrient receptors |
Q37050630 | Dehydroeburicoic Acid from Antrodia camphorata Prevents the Diabetic and Dyslipidemic State via Modulation of Glucose Transporter 4, Peroxisome Proliferator-Activated Receptor α Expression and AMP-Activated Protein Kinase Phosphorylation in High-Fat |
Q34615425 | Diet and gastrointestinal bypass-induced weight loss: the roles of ghrelin and peptide YY. |
Q48542374 | Diet-induced changes in hypothalamic pro-opio-melanocortin mRNA in the rat hypothalamus |
Q53886784 | Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice. |
Q33815101 | Diet-induced effects on neuronal and glial elements in the middle-aged rat hippocampus |
Q39436138 | Diet-induced obesity has neuroprotective effects in murine gastric enteric nervous system: involvement of leptin and glial cell line-derived neurotrophic factor |
Q38790215 | Dietary Shiitake Mushroom (Lentinus edodes) Prevents Fat Deposition and Lowers Triglyceride in Rats Fed a High-Fat Diet. |
Q38089575 | Dietary components in the development of leptin resistance |
Q38014600 | Dietary factors affect food reward and motivation to eat. |
Q35608714 | Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice |
Q47860039 | Dietary nitrite reverses features of postmenopausal metabolic syndrome induced by high-fat diet and ovariectomy in mice |
Q50454502 | Dietary restriction reduces blood lipids and ameliorates liver function of mice with hyperlipidemia. |
Q46682226 | Dietary strawberry powder reduces blood glucose concentrations in obese and lean C57BL/6 mice, and selectively lowers plasma C-reactive protein in lean mice |
Q49612956 | Diets High in Fat or Fructose Differentially Modulate Bone Health and Lipid Metabolism |
Q44522507 | Differential effects of fatty acids and exercise on body weight regulation and metabolism in female Wistar rats |
Q55417875 | Differential effects of high fat diet and diet-induced obesity on skeletal acquisition in female C57BL/6J vs. FVB/NJ Mice. |
Q47606062 | Differential physiological responses to central leptin overexpression in male and female rats. |
Q35040219 | Differential responses of hepatic endoplasmic reticulum stress and inflammation in diet-induced obese rats with high-fat diet rich in lard oil or soybean oil |
Q47868205 | Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity |
Q41868317 | Downregulation of RelA (p65) by Rapamycin Inhibits Murine Adipocyte Differentiation and Reduces Fat Mass of C57BL/6J Mice despite High Fat Diet |
Q33772367 | Early overnutrition results in early-onset arcuate leptin resistance and increased sensitivity to high-fat diet |
Q46943798 | Early stage of obesity potentiates nitric oxide reduction during the development of renal failure |
Q34844098 | Effect of Argyreia speciosa root extract on cafeteria diet-induced obesity in rats |
Q36782016 | Effect of Cheonggukjang supplementation upon hepatic acyl-CoA synthase, carnitine palmitoyltransferase I, acyl-CoA oxidase and uncoupling protein 2 mRNA levels in C57BL/6J mice fed with high fat diet |
Q33845495 | Effect of a high-fat diet in development of colonic adenoma in an animal model |
Q57826548 | Effect of different intensities of physical activity on cardiometabolic markers and vascular and cardiac function in adult rats fed with a high-fat high-carbohydrate diet |
Q47363942 | Effect of food deprivation or short-term Western diet feeding on BDNF protein expression in the hypothalamic arcuate, paraventricular, and ventromedial nuclei |
Q39324576 | Effect of peripherally administered leptin antagonist on whole body metabolism and bone microarchitecture and biomechanical properties in the mouse |
Q88412501 | Effects of Angelica dahurica on obesity and fatty liver in mice |
Q90657745 | Effects of Gut Microbiota on Leptin Expression and Body Weight Are Lessened by High-fat Diet in Mice |
Q46090303 | Effects of a physical and energetic challenge on male California mice (Peromyscus californicus): modulation by reproductive condition. |
Q37462887 | Effects of atherogenic diet on hepatic gene expression across mouse strains |
Q36853022 | Effects of chronic central leptin infusion on proopiomelanocortin and neurotensin gene expression in the rat hypothalamus |
Q99576137 | Effects of high fat diet and maternal binge-like alcohol consumption and their influence on cocaine response in female mice offspring |
Q37246527 | Effects of the Cellcultured Acanthopanax senticosus Extract on Antioxidative Defense System and Membrane Fluidity in the Liver of Type 2 Diabetes Mouse |
Q98177178 | Elafin inhibits obesity, hyperglycemia, and liver steatosis in high-fat diet-treated male mice |
Q40544270 | Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle |
Q34329517 | Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3. |
Q36281656 | Excess Linoleic Acid Increases Collagen I/III Ratio and "Stiffens" the Heart Muscle Following High Fat Diets |
Q46779704 | Exercise training promotes cardioprotection through oxygen-sparing action in high fat-fed mice |
Q47368615 | Factors predicting nongenetic variability in body weight gain induced by a high-fat diet in inbred C57BL/6J mice |
Q36008526 | Fasting-induced reductions in cardiovascular and metabolic variables occur sooner in obese versus lean mice. |
Q54641117 | Fat deposition pattern and mechanism in response to dietary lipid levels in grass carp, Ctenopharyngodon idellus. |
Q41903348 | Four-Week Consumption of Malaysian Honey Reduces Excess Weight Gain and Improves Obesity-Related Parameters in High Fat Diet Induced Obese Rats |
Q46375508 | Fructose-induced leptin resistance: discovery of an unsuspected form of the phenomenon and its significance. Focus on "Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding," by Shapiro et al. |
Q33493427 | Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program |
Q33825537 | Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse. |
Q48598795 | Green tea (-)-epigallocatechin-3-gallate counteracts daytime overeating induced by high-fat diet in mice |
Q55346929 | Hedonic Eating and the "Delicious Circle": From Lipid-Derived Mediators to Brain Dopamine and Back. |
Q34706389 | Hepatic gene expression profiles are altered by dietary unsalted korean fermented soybean (chongkukjang) consumption in mice with diet-induced obesity |
Q39728657 | Hexosamine biosynthetic pathway activity in leptin resistant sucrose-drinking rats |
Q37146523 | High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance |
Q41654655 | High fat diet augments amphetamine sensitization in mice: Role of feeding pattern, obesity, and dopamine terminal changes |
Q50000860 | High fat diet sensitizes fibromyalgia-like pain behaviors in mice via tumor necrosis factor alpha. |
Q40169192 | High fat diet-induced obesity increases the formation of colon polyps induced by azoxymethane in mice |
Q36102802 | High-Fat, High-Calorie Diet Enhances Mammary Carcinogenesis and Local Inflammation in MMTV-PyMT Mouse Model of Breast Cancer |
Q30586174 | High-Fat-Diet-Induced Weight Gain Ameliorates Bone Loss without Exacerbating AβPP Processing and Cognition in Female APP/PS1 Mice |
Q47275063 | High-calcium diet with whey protein attenuates body-weight gain in high-fat-fed C57Bl/6J mice. |
Q83531125 | High-fat diet alters gene expression in the liver and colon: links to increased development of aberrant crypt foci |
Q53593111 | High-fat diet decreases energy expenditure and expression of genes controlling lipid metabolism, mitochondrial function and skeletal system development in the adipose tissue, along with increased expression of extracellular matrix remodelling- and i |
Q46946960 | High-fat diet exposure increases dopamine D2 receptor and decreases dopamine transporter receptor binding density in the nucleus accumbens and caudate putamen of mice |
Q42711721 | High-fat diet-induced hypertension and autonomic imbalance are associated with an upregulation of CART in the dorsomedial hypothalamus of mice. |
Q37803278 | High-fat diet-induced obesity in animal models |
Q37112827 | Hyperleptinemia is associated with parameters of low-grade systemic inflammation and metabolic dysfunction in obese human beings |
Q33627582 | Hyperleptinemia is required for the development of leptin resistance |
Q36300428 | Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity |
Q36509764 | Hypothalamic phosphatidylinositol 3-kinase pathway of leptin signaling is impaired during the development of diet-induced obesity in FVB/N mice |
Q46747353 | Hypothalamic phosphatidylinositol 3-kinase-phosphodiesterase 3B-cyclic AMP pathway of leptin signalling is impaired following chronic central leptin infusion |
Q38341044 | Impact of Obesity and Leptin on Protein Expression Profiles in Mouse Colon |
Q50278777 | Impaired intestinal afferent nerve satiety signalling and vagal afferent excitability in diet induced obesity in the mouse |
Q35951065 | In Vitro and in Vivo Anti-Diabetic Effects of Anthocyanins from Maqui Berry (Aristotelia chilensis). |
Q33813278 | Inactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake |
Q90333177 | Increased adiposity by feeding growing rats a high-fat diet results in iron decompartmentalisation |
Q34547482 | Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice |
Q92886447 | Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet |
Q27320899 | Insights into the molecular mechanisms of the anti-atherogenic actions of flavonoids in normal and obese mice |
Q64275760 | Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice |
Q45210539 | Integrative systems analysis of diet-induced obesity identified a critical transition in the transcriptomes of the murine liver and epididymal white adipose tissue |
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Q92107340 | Interleukin-13 and its signaling pathway is associated with obesity-related colorectal tumorigenesis |
Q35222301 | Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons |
Q35088709 | Intracellular leptin-signaling pathways in hypothalamic neurons: the emerging role of phosphatidylinositol-3 kinase-phosphodiesterase-3B-cAMP pathway |
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Q58586958 | Invalidation of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Reduces Diet-Induced Low-Grade Inflammation and Adiposity |
Q92050501 | L-Arabinose Elicits Gut-Derived Hydrogen Production and Ameliorates Metabolic Syndrome in C57BL/6J Mice on High-Fat-Diet |
Q58549325 | Leptin Selectively Regulates Nutrients Metabolism in Nile Tilapia Fed on High Carbohydrate or High Fat Diet |
Q54708917 | Leptin action is modified by an interaction between dietary fat content and ambient temperature. |
Q26865989 | Leptin as regulator of pulmonary immune responses: involvement in respiratory diseases |
Q39972653 | Leptin infusion and obesity in mouse cause alterations in the hypothalamic melanocortin system |
Q54038740 | Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain. |
Q34571659 | Leptin resistance and obesity |
Q44462706 | Leptin resistance in mice is determined by gender and duration of exposure to high-fat diet |
Q37151048 | Leptin resistance: a prediposing factor for diet-induced obesity |
Q43915861 | Leptin responsiveness in mice that ectopically express agouti protein |
Q73342203 | Leptin responsiveness of juvenile rats: proof of leptin function within the physiological range |
Q35630443 | Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance |
Q37179795 | Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice |
Q35990442 | Leptin: at the crossroads of energy balance and systemic inflammation |
Q36438742 | Lipid phosphatases as drug discovery targets for type 2 diabetes. |
Q46397407 | Liver TAG transiently decreases while PL n-3 and n-6 fatty acids are persistently elevated in insulin resistant mice |
Q45924315 | Long term effects of high fat and sucrose diets on obesity and lymphocyte proliferation in mice. |
Q47198622 | Long-term effects of exogenous leptin on body weight and fat in post-obese female rats |
Q62563676 | Low and High Fat Diets Inconsistently Induce Obesity in C57BL/6J Mice and Obesity Compromises n-3 Fatty Acid Status |
Q51733170 | Low-Fat Diet With Caloric Restriction Reduces White Matter Microglia Activation During Aging. |
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Q37628465 | Mass Spectrometry-Based Metabolomic and Lipidomic Analyses of the Effects of Dietary Platycodon grandiflorum on Liver and Serum of Obese Mice under a High-Fat Diet |
Q37209135 | Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity. |
Q37200084 | Mechanisms mediating renal sympathetic activation to leptin in obesity |
Q51686950 | Metabolic and behavioral responses to high-fat feeding in mice selectively bred for high wheel-running activity. |
Q34510930 | Methionine-restricted C57BL/6J mice are resistant to diet-induced obesity and insulin resistance but have low bone density |
Q47385008 | Mice with low metabolic rates are not susceptible to weight gain when fed a high-fat diet. |
Q36429301 | Microalgal Oil Supplementation Has an Anti-Obesity Effect in C57BL/6J Mice Fed a High Fat Diet |
Q37252529 | Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload. |
Q35718369 | Moderate intensity physical activity prevents increased blood glucose concentrations, fat pad deposition and cardiac action potential prolongation following diet-induced obesity in a juvenile-adolescent rat model |
Q35259519 | Molecular signatures for obesity and associated disorders identified through partial least square regression models |
Q35796917 | Multimodality imaging of β-cells in mouse models of type 1 and 2 diabetes |
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Q38593744 | New insights in leptin resistance mechanisms in mice |
Q92327805 | Nonalcoholic Fatty Liver Disease Induced by High-Fat Diet in C57bl/6 Models |
Q34318314 | Nutrient sensing, leptin and insulin action |
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Q33894841 | Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching |
Q35765687 | Oestradiol and diet modulate energy homeostasis and hypothalamic neurogenesis in the adult female mouse. |
Q38863968 | Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet |
Q37681857 | PFOS induced lipid metabolism disturbances in BALB/c mice through inhibition of low density lipoproteins excretion |
Q37039729 | PGC-1α expression in murine AgRP neurons regulates food intake and energy balance. |
Q64101623 | Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy Metabolism |
Q36511320 | Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity |
Q42473219 | Phosphodiesterase-3B-cAMP pathway of leptin signalling in the hypothalamus is impaired during the development of diet-induced obesity in FVB/N mice. |
Q44107938 | Phyllodulcin, a Natural Sweetener, Regulates Obesity-Related Metabolic Changes and Fat Browning-Related Genes of Subcutaneous White Adipose Tissue in High-Fat Diet-Induced Obese Mice |
Q38324686 | Physical activity opposes coronary vascular dysfunction induced during high fat feeding in mice. |
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Q35092933 | Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL/6J mice. |
Q47398788 | RNA-Sequencing of Drosophila melanogaster Head Tissue on High-Sugar and High-Fat Diets |
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Q36578767 | Selective loss of leptin receptors in the ventromedial hypothalamic nucleus results in increased adiposity and a metabolic syndrome |
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Q48141076 | Short-term high-fat diet increases the presence of astrocytes in the hypothalamus of C57BL6 mice without altering leptin sensitivity. |
Q42014982 | Silk and silkworm pupa peptides suppress adipogenesis in preadipocytes and fat accumulation in rats fed a high-fat diet |
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Q36665054 | Time-dependent behavioral, neurochemical, and metabolic dysregulation in female C57BL/6 mice caused by chronic high-fat diet intake. |
Q34275922 | Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet |
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Q43849983 | Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes |
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