Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice

scientific article published on 07 January 2020

Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41366-019-0513-Y
P698PubMed publication ID31911662

P2093author name stringJianping Weng
Fen Xu
Zonglan Chen
Huimin Gu
Huanyi Cao
Beisi Lin
Wanrong Guo
P2860cites workPatients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor AgonistQ60173685
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Exendin-4 Improves Nonalcoholic Fatty Liver Disease by Regulating Glucose Transporter 4 Expression in ob/ob MiceQ34097903
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Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcriptionQ42247586
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SIRT1 mediates the effect of GLP-1 receptor agonist exenatide on ameliorating hepatic steatosisQ43412126
Comparison of the effects on glycaemic control and β-cell function in newly diagnosed type 2 diabetes patients of treatment with exenatide, insulin or pioglitazone: a multicentre randomized parallel-group trial (the CONFIDENCE study).Q43769439
Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid contentQ46770144
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 studyQ47956183
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Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation.Q51484711
Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.Q54095921
Chronic leptin treatment stimulates lipid oxidation in immortalized and primary mouse skeletal muscle cells.Q54778713
Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.Q55033199
The role of leptin in human lipid and glucose metabolism: the effects of acute recombinant human leptin infusion in young healthy malesQ59326156
Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J miceQ59328728
Leptin Directly Alters Lipid Partitioning in Skeletal MuscleQ59515980
P433issue4
P304page(s)937-947
P577publication date2020-01-07
P1433published inInternational Journal of ObesityQ6051519
P1476titleShort-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice
P478volume44

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