review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S00018-009-0188-Y |
P698 | PubMed publication ID | 19915993 |
P50 | author | Francisco J. Blanco | Q16251242 |
Inés G. Muñoz | Q42859143 | ||
Maria J Marcaida | Q48547074 | ||
P2093 | author name string | Guillermo Montoya | |
Jesús Prieto | |||
P2860 | cites work | Mutations specific to the xeroderma pigmentosum group E Ddb- phenotype | Q24322600 |
Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line | Q24514763 | ||
Intertwined structure of the DNA-binding domain of intron endonuclease I-TevI with its substrate. | Q24535579 | ||
Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells | Q24535831 | ||
Mutations altering the cleavage specificity of a homing endonuclease | Q24537781 | ||
X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase. | Q24538965 | ||
Familial porphyria cutanea tarda: characterization of seven novel uroporphyrinogen decarboxylase mutations and frequency of common hemochromatosis alleles | Q24539508 | ||
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae | Q24548535 | ||
Behavior of restriction-modification systems as selfish mobile elements and their impact on genome evolution | Q24555229 | ||
Characterization of the restriction site of a prokaryotic intron-encoded endonuclease | Q24558625 | ||
A general two-metal-ion mechanism for catalytic RNA | Q24562157 | ||
Computational redesign of endonuclease DNA binding and cleavage specificity | Q24569661 | ||
Strand-specific contacts and divalent metal ion regulate double-strand break formation by the GIY-YIG homing endonuclease I-BmoI | Q64387785 | ||
The genetics of the hereditary xeroderma pigmentosum syndrome | Q64387883 | ||
Selection of a remote cleavage site by I-tevI, the td intron-encoded endonuclease | Q64389592 | ||
Epidermal morphogenesis and induction of the 67 kD keratin polypeptide by culture of human keratinocytes at the liquid-air interface | Q68940208 | ||
New approaches to understanding Lesch-Nyhan disease | Q71073952 | ||
Xeroderma pigmentosum. Complementation group C and malignant melanoma | Q71268962 | ||
New tumor formation on split-thickness skin grafted areas in xeroderma pigmentosum | Q73271909 | ||
Structural parsimony in endonuclease active sites: should the number of homing endonuclease families be redefined? | Q73280737 | ||
Resurfacing the dorsum of the hand in a patient with Xeroderma pigmentosum | Q73579786 | ||
A similar active site for non-specific and specific endonucleases | Q74523726 | ||
Relationship of the C242T p22phox gene polymorphism to angiographic coronary artery disease and endothelial function | Q78107902 | ||
Chronic granulomatous disease caused by mutations other than the common GT deletion in NCF1, the gene encoding the p47phox component of the phagocyte NADPH oxidase | Q80260413 | ||
Autoimmune polyendocrinopathy--candidosis--ectodermal dystrophy (APECED): autosomal recessive inheritance | Q93594572 | ||
Homing endonuclease structure and function | Q34473961 | ||
Does heterozygous beta-thalassemia confer a protection against coronary artery disease? | Q34474608 | ||
Gene therapy: X-SCID transgene leukaemogenicity | Q34567588 | ||
Modeling the therapeutic efficacy of p53 restoration in tumors | Q34593294 | ||
New founder germline mutations of CDKN2A in melanoma-prone families and multiple primary melanoma development in a patient receiving levodopa treatment. | Q34626994 | ||
Evolutionarily conserved and functionally important residues in the I-CeuI homing endonuclease | Q34630818 | ||
Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells | Q34636305 | ||
Statistical modeling and analysis of the LAGLIDADG family of site-specific endonucleases and identification of an intein that encodes a site-specific endonuclease of the HNH family | Q34645548 | ||
Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells | Q34784813 | ||
The nicking homing endonuclease I-BasI is encoded by a group I intron in the DNA polymerase gene of the Bacillus thuringiensis phage Bastille | Q35109019 | ||
Segregation analysis with uncertain ascertainment: application to Fanconi anemia | Q35245762 | ||
Identification and characterization of nine RFLPs at the adenosine deaminase (ADA) locus | Q35248529 | ||
New types of conserved sequence domains in DNA-binding regions of homing endonucleases | Q35296069 | ||
N-terminal RAG1 frameshift mutations in Omenn's syndrome: internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role in vivo for the N-terminal domains. | Q35850311 | ||
RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair. | Q35856709 | ||
Mobile group II introns | Q35965810 | ||
Crystallization and preliminary X-ray studies of I-PpoI: a nuclear, intron-encoded homing endonuclease from Physarum polycephalum | Q36280256 | ||
Uroporphyrinogen 3 cosynthetase in human congenital erythropoietic porphyria | Q36448840 | ||
Hematopoietic stem-cell transplantation | Q36461248 | ||
Analysis of DNA double-strand break repair pathways in mice | Q36517406 | ||
Differential usage of non-homologous end-joining and homologous recombination in double strand break repair | Q36522562 | ||
Related homing endonucleases I-BmoI and I-TevI use different strategies to cleave homologous recognition sites | Q36529061 | ||
A protein encoded by a group I intron in Aspergillus nidulans directly assists RNA splicing and is a DNA endonuclease | Q36546473 | ||
A mobile group I intron from Physarum polycephalum can insert itself and induce point mutations in the nuclear ribosomal DNA of saccharomyces cerevisiae | Q36661174 | ||
Co-ordination of DNA single strand break repair | Q36661965 | ||
Characterization of I-Ppo, an intron-encoded endonuclease that mediates homing of a group I intron in the ribosomal DNA of Physarum polycephalum | Q36714793 | ||
Meganucleases and DNA double-strand break-induced recombination: perspectives for gene therapy | Q36737863 | ||
Interaction of the intron-encoded mobility endonuclease I-PpoI with its target site | Q36827630 | ||
Expression of protein-coding genes embedded in ribosomal DNA. | Q36850001 | ||
Structural biology of the tumor suppressor p53. | Q37137883 | ||
Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease | Q37146915 | ||
I-TevI, the endonuclease encoded by the mobile td intron, recognizes binding and cleavage domains on its DNA target | Q37586978 | ||
Intron-encoded endonuclease I-TevI binds as a monomer to effect sequential cleavage via conformational changes in the td homing site. | Q37625189 | ||
The structural basis of damaged DNA recognition and endonucleolytic cleavage for very short patch repair endonuclease | Q33941852 | ||
Genetic analysis of the Chlamydomonas reinhardtii I-CreI mobile intron homing system in Escherichia coli | Q33971499 | ||
Gene conversion tracts from double-strand break repair in mammalian cells | Q33995776 | ||
Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI. | Q34064923 | ||
A 76-kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: possible involvement in the genesis of the Philadelphia chromosome translocation | Q34076060 | ||
Mutations in severe combined immune deficiency (SCID) due to JAK3 deficiency. | Q34098712 | ||
The phage T4 nrdB intron: a deletion mutant of a version found in the wild | Q34114074 | ||
A self-splicing group I intron in the DNA polymerase gene of Bacillus subtilis bacteriophage SPO1. | Q34157210 | ||
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells | Q34200585 | ||
Adenosine deaminase deficiency: Frequency and comparative pathology in autosomally recessive severe combined immunodeficiency | Q34218448 | ||
Double-strand-break-induced homologous recombination in mammalian cells | Q34253008 | ||
Natural history of paroxysmal nocturnal hemoglobinuria | Q34296074 | ||
An intron in the nuclear ribosomal DNA of Didymium iridis codes for a group I ribozyme and a novel ribozyme that cooperate in self-splicing | Q34336918 | ||
Beyond homing: competition between intron endonucleases confers a selective advantage on flanking genetic markers | Q34371890 | ||
Group I intron homing in Bacillus phages SPO1 and SP82: a gene conversion event initiated by a nicking homing endonuclease | Q34435844 | ||
The DNA polymerase genes of several HMU-bacteriophages have similar group I introns with highly divergent open reading frames | Q24606570 | ||
Structural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factor | Q24630148 | ||
Fractured genes: a novel genomic arrangement involving new split inteins and a new homing endonuclease family | Q24649588 | ||
Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae | Q24652685 | ||
Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease | Q24654113 | ||
High-frequency modification of plant genes using engineered zinc-finger nucleases | Q24654686 | ||
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences | Q24670002 | ||
The restriction fold turns to the dark side: a bacterial homing endonuclease with a PD-(D/E)-XK motif | Q24673408 | ||
Homing endonuclease I-CreI derivatives with novel DNA target specificities | Q24674606 | ||
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes | Q24684053 | ||
The recent transfer of a homing endonuclease gene | Q24802877 | ||
In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombination | Q24811303 | ||
Potentiation of gene targeting in human cells by expression of Saccharomyces cerevisiae Rad52 | Q24813430 | ||
A novel endonuclease mechanism directly visualized for I-PpoI | Q27620540 | ||
Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site | Q27625320 | ||
The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites | Q27630852 | ||
Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence | Q27639613 | ||
Catalytic domain structure and hypothesis for function of GIY-YIG intron endonuclease I-TevI | Q27639807 | ||
Crystal structure of the thermostable archaeal intron-encoded endonuclease I-DmoI | Q27639829 | ||
Design, activity, and structure of a highly specific artificial endonuclease | Q27639919 | ||
Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI | Q27641297 | ||
The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity | Q27642627 | ||
Mutability of an HNH nuclease imidazole general base and exchange of a deprotonation mechanism | Q27644841 | ||
Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway | Q27650402 | ||
Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering | Q27652711 | ||
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases | Q27652792 | ||
Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins | Q27653454 | ||
Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution | Q27730328 | ||
The structure of I-Crel, a group I intron-encoded homing endonuclease | Q27739151 | ||
DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI | Q27764571 | ||
The role of metals in catalysis by the restriction endonuclease BamHI | Q27765729 | ||
DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI | Q27765995 | ||
Directed evolution and substrate specificity profile of homing endonuclease I-SceI. | Q27936586 | ||
Role of the interdomain linker in distance determination for remote cleavage by homing endonuclease I-TevI. | Q38290691 | ||
R.KpnI, an HNH superfamily REase, exhibits differential discrimination at non-canonical sequences in the presence of Ca2+ and Mg2+. | Q38302770 | ||
Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor | Q38336787 | ||
Degenerate DNA recognition by I-PpoI endonuclease. | Q38340018 | ||
Purification, biochemical characterization and protein-DNA interactions of the I-CreI endonuclease produced in Escherichia coli | Q38342598 | ||
Profile of the DNA recognition site of the archaeal homing endonuclease I-DmoI. | Q38346827 | ||
Substrate binding and turnover by the highly specific I-PpoI endonuclease. | Q38362623 | ||
An in vivo selection system for homing endonuclease activity | Q39538487 | ||
Biochemical characterization of I-CmoeI reveals that this H-N-H homing endonuclease shares functional similarities with H-N-H colicins | Q39600917 | ||
Configuration of the catalytic GIY-YIG domain of intron endonuclease I-TevI: coincidence of computational and molecular findings | Q39728000 | ||
Mammalian gene targeting with designed zinc finger nucleases | Q40371944 | ||
A family of nuclear homing endonucleases. | Q40410128 | ||
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis | Q40562330 | ||
Self-splicing group I intron in cyanobacterial initiator methionine tRNA: evidence for lateral transfer of introns in bacteria | Q40793395 | ||
Tissue-specific alternative splicing in the human INK4a/ARF cell cycle regulatory locus | Q40935835 | ||
AG dinucleotide insertion in a patient with chronic granulomatous disease lacking cytosolic 67-kD protein. | Q41328402 | ||
Activity and specificity of the bacterial PD-(D/E)XK homing endonuclease I-Ssp6803I. | Q41425873 | ||
Identification of a single HNH active site in type IIS restriction endonuclease Eco31I. | Q42009522 | ||
Phage T4 SegB protein is a homing endonuclease required for the preferred inheritance of T4 tRNA gene region occurring in co-infection with a related phage | Q42028906 | ||
Molecular basis for alpha-thalassemia associated with the structural mutant hemoglobin Suan-Dok (alpha 2 109leu----arg) | Q42138102 | ||
Metal-dependent DNA cleavage mechanism of the I-CreI LAGLIDADG homing endonuclease | Q42168586 | ||
Unconventional GIY-YIG homing endonuclease encoded in group I introns in closely related strains of the Bacillus cereus group | Q42183439 | ||
Genetic correction of DNA repair-deficient/cancer-prone xeroderma pigmentosum group C keratinocytes | Q42444805 | ||
Cleavage and recognition pattern of a double-strand-specific endonuclease (I-creI) encoded by the chloroplast 23S rRNA intron of Chlamydomonas reinhardtii | Q42603591 | ||
The catalytic group-I introns of the psbA gene of chlamydomonas reinhardtii : core structures, ORFs and evolutionary implications | Q42607861 | ||
SegG endonuclease promotes marker exclusion and mediates co-conversion from a distant cleavage site | Q42612439 | ||
Functional characterization of isoschizomeric His-Cys box homing endonucleases from Naegleria | Q42638572 | ||
A novel group I intron-encoded endonuclease specific for the anticodon region of tRNA(fMet) genes | Q42645053 | ||
In vivo mobility of a group I twintron in nuclear ribosomal DNA of the myxomycete Didymium iridis | Q42658745 | ||
I-NjaI, a nuclear intron-encoded homing endonuclease from Naegleria, generates a pentanucleotide 3' cleavage-overhang within a 19 base-pair partially symmetric DNA recognition site | Q42690366 | ||
Thermodynamics of DNA target site recognition by homing endonucleases. | Q42920176 | ||
HNH family subclassification leads to identification of commonality in the His-Me endonuclease superfamily | Q43104961 | ||
Distance determination by GIY-YIG intron endonucleases: discrimination between repression and cleavage functions | Q43257111 | ||
Selfish DNA: new abode for homing endonucleases | Q43439091 | ||
Engineering of restriction endonucleases: using methylation activity of the bifunctional endonuclease Eco57I to select the mutant with a novel sequence specificity | Q44356433 | ||
Acute intermittent porphyria--impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties | Q45775369 | ||
Questions linger about unexplained gene-therapy trial death | Q45858907 | ||
Genetic correction of sickle cell disease: insights using transgenic mouse models | Q45864964 | ||
Identification of 217 unreported mutations in the F8 gene in a group of 1,410 unselected Italian patients with hemophilia A. | Q45874679 | ||
Haemophilia B mutations in Sweden: a population-based study of mutational heterogeneity | Q45876762 | ||
Deterministic regulation of hematopoietic stem cell self-renewal and differentiation. | Q46163240 | ||
Cancer in xeroderma pigmentosum and related disorders of DNA repair | Q46465906 | ||
Silent exonic mutations in the low-density lipoprotein receptor gene that cause familial hypercholesterolemia by affecting mRNA splicing | Q46654772 | ||
RAG proteins shepherd double-strand breaks to a specific pathway, suppressing error-prone repair, but RAG nicking initiates homologous recombination | Q47765927 | ||
Detection of RAG mutations and prenatal diagnosis in families presenting with either T-B- severe combined immunodeficiency or Omenn's syndrome | Q47940148 | ||
Oligomeric structure diversity within the GIY-YIG nuclease family | Q48020673 | ||
I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition | Q48416651 | ||
Mutations and polymorphisms in the human ornithine transcarbamylase (OTC) gene. | Q48492547 | ||
Identification of a new subfamily of HNH nucleases and experimental characterization of a representative member, HphI restriction endonuclease. | Q51121910 | ||
From monomeric to homodimeric endonucleases and back: engineering novel specificity of LAGLIDADG enzymes. | Q51154994 | ||
Hin4II, a new prototype restriction endonuclease from Haemophilus influenzae RFL4: discovery, cloning and expression in Escherichia coli. | Q51280499 | ||
High-frequency homologous recombination in plants mediated by zinc-finger nucleases. | Q51327085 | ||
Custom zinc-finger nucleases for use in human cells. | Q51391970 | ||
Chimeras of the homing endonuclease PI-SceI and the homologous Candida tropicalis intein: a study to explore the possibility of exchanging DNA-binding modules to obtain highly specific endonucleases with altered specificity. | Q51715930 | ||
Three-dimensional modeling of the I-TevI homing endonuclease catalytic domain, a GIY-YIG superfamily member, using NMR restraints and Monte Carlo dynamics. | Q52050322 | ||
Coincidence of cleavage sites of intron endonuclease I-TevI and critical sequences of the host thymidylate synthase gene. | Q54497541 | ||
The td intron endonuclease I-TevI makes extensive sequence-tolerant contacts across the minor groove of its DNA target. | Q55549287 | ||
CD40 Ligand Gene Defects Responsible for X-Linked Hyper-IgM Syndrome | Q55670500 | ||
Identical mutations in RAG1 or RAG2 genes leading to defective V(D)J recombinase activity can cause either T-B-severe combined immune deficiency or Omenn syndrome | Q55670920 | ||
The Structure of I-CeuI Homing Endonuclease: Evolving Asymmetric DNA Recognition from a Symmetric Protein Scaffold | Q57240373 | ||
Two-domain structure of the td intron-encoded endonuclease I-TevI correlates with the two-domain configuration of the homing site | Q59622199 | ||
Molecular background of polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome in a Polish population: novel AIRE mutations and an estimate of disease prevalence | Q59697428 | ||
Clinical and immunologic consequences of a somatic reversion in a patient with X-linked severe combined immunodeficiency | Q61701733 | ||
The maturase encoded by a group I intron from Aspergillus nidulans stabilizes RNA tertiary structure and promotes rapid splicing | Q62696756 | ||
Identification of mutations in the uroporphyrinogen III cosynthase gene in German patients with congenital erythropoietic porphyria | Q64046016 | ||
A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy | Q28142117 | ||
Group II introns: structure and catalytic versatility of large natural ribozymes | Q28188097 | ||
Enhancing Gene Targeting with Designed Zinc Finger Nucleases | Q28202461 | ||
Chromosomal stability and the DNA double-stranded break connection | Q28205315 | ||
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 | Q28210584 | ||
Nucleases and helicases take center stage in homologous recombination | Q28241737 | ||
Highly efficient endogenous human gene correction using designed zinc-finger nucleases | Q28243157 | ||
Mechanism of homologous recombination: mediators and helicases take on regulatory functions | Q28259452 | ||
Gene targeting using zinc finger nucleases | Q28265983 | ||
The double-strand-break repair model for recombination | Q28267259 | ||
A review of the molecular genetics of the human alpha-globin gene cluster | Q28268949 | ||
Systematic analysis of molecular defects in the ferrochelatase gene from patients with erythropoietic protoporphyria | Q28270688 | ||
Mutations in human CPO gene predict clinical expression of either hepatic hereditary coproporphyria or erythropoietic harderoporphyria | Q28272057 | ||
Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways | Q28275827 | ||
Isolation and characterization of new homing endonuclease specificities at individual target site positions | Q28277286 | ||
DNA binding and cleavage by the HNH homing endonuclease I-HmuI | Q28277295 | ||
Engineering of large numbers of highly specific homing endonucleases that induce recombination on novel DNA targets | Q28283796 | ||
Molecular characterization of homozygous variegate porphyria | Q28288554 | ||
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases | Q28307957 | ||
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells | Q28511551 | ||
Pathways of DNA double-strand break repair during the mammalian cell cycle | Q28608969 | ||
Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility | Q28775736 | ||
Single-strand break repair and genetic disease | Q29615347 | ||
Chimeric nucleases stimulate gene targeting in human cells | Q29615384 | ||
Restoration of p53 function leads to tumour regression in vivo | Q29618727 | ||
Generation of induced pluripotent stem cells using recombinant proteins | Q29619162 | ||
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue | Q29620725 | ||
Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design | Q30789079 | ||
Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site | Q30883432 | ||
Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system | Q31029529 | ||
Phylogenomic analysis of the GIY-YIG nuclease superfamily | Q33241531 | ||
Altered target site specificity variants of the I-PpoI His-Cys box homing endonuclease | Q33295151 | ||
Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences | Q33319940 | ||
Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells | Q33774945 | ||
High-frequency gene targeting in Arabidopsis plants expressing the yeast RAD54 gene | Q33922824 | ||
Peripheral blood stem cells for allogeneic transplantation: a review | Q33937058 | ||
P433 | issue | 5 | |
P304 | page(s) | 727-748 | |
P577 | publication date | 2010-03-01 | |
P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
P1476 | title | Homing endonucleases: from basics to therapeutic applications | |
P478 | volume | 67 |
Q37874949 | Artificial DNA cutters for DNA manipulation and genome engineering |
Q53206635 | Bricks and blueprints: methods and standards for DNA assembly. |
Q34661562 | Circular permutation of a synthetic eukaryotic chromosome with the telomerator |
Q40396022 | Creating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases. |
Q36323430 | Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification. |
Q37606361 | Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA. |
Q33791259 | Development of synthetic selfish elements based on modular nucleases in Drosophila melanogaster |
Q34080512 | Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells |
Q38950047 | EheA from Exiguobacterium sp. yc3 is a novel thermostable DNase belonging to HNH endonuclease superfamily. |
Q35883835 | Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold. |
Q90142616 | Enzyme-Mediated Endogenous and Bioorthogonal Control of a DNAzyme Fluorescent Sensor for Imaging Metal Ions in Living Cells |
Q48001268 | Fight against malaria with genetically modified mosquitoes |
Q37664073 | Gene conversion in human genetic disease |
Q37874216 | Generation of novel nucleases with extended specificity by rational and combinatorial strategies. |
Q37894826 | Genetic strategies for the treatment of sickle cell anaemia |
Q34982862 | Genetic therapies for cystic fibrosis lung disease |
Q42657054 | Genome sequence of temperate bacteriophage Psymv2 from Antarctic Dry Valley soil isolate Psychrobacter sp. MV2. |
Q35193924 | HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs |
Q27023722 | Homing endonucleases: DNA scissors on a mission |
Q35621488 | Homing endonucleases: from genetic anomalies to programmable genomic clippers |
Q45858948 | Insertion of Group II Intron-Based Ribozyme Switches into Homing Endonuclease Genes |
Q50508358 | Invasion of protein coding genes by green algal ribosomal group I introns. |
Q27664531 | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus |
Q37979243 | Molecular scissors for in situ cellular repair |
Q35991442 | Monomeric site-specific nucleases for genome editing |
Q27678463 | Non-specific protein-DNA interactions control I-CreI target binding and cleavage |
Q38025056 | Recent advances in targeted genome engineering in mammalian systems |
Q37991511 | Restriction endonucleases: natural and directed evolution |
Q39875872 | Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats |
Q33844698 | Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. |
Q35070354 | TALE-PvuII fusion proteins--novel tools for gene targeting. |
Q27670974 | Tapping natural reservoirs of homing endonucleases for targeted gene modification |
Q38146885 | Targeted mutagenesis tools for modelling psychiatric disorders. |
Q38254476 | Technology developments in biological tools for targeted genome surgery |
Q51054238 | Three new active members of the I-OnuI family of homing endonucleases. |
Q37853621 | Transient DNA / RNA-protein interactions. |
Q61947456 | Understanding the indirect DNA read-out specificity of I-CreI Meganuclease |
Q36559275 | Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system |
Q27696542 | Visualizing phosphodiester-bond hydrolysis by an endonuclease |
Q41124443 | rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion protein |
Search more.